Neurology Minute

In part one of this series, Dr. Justin Abbatemarco and Dr. Alberto Priori discussed the use of artificial intelligence in neurology among peers, not just trainees.  Show citation:  Vozzi C, Sibilla M, Sandri D, et al. Education Research: Bridging the Artificial Intelligence Training Gap: Evidence from a National Survey of Italian Neurology Residents. Neurol Educ. 2026;5(1):e200289. Published 2026 Jan 27. doi:10.1212/NE9.0000000000200289  

In the September episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost discuss BrainHealth.com and the AAN's expanding brain health movement.  Stay informed by watching the President's Spotlight video.  

In the fifth episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss dexamethasone and listeria meningitis. 

In the fourth episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss the use of dexamethasone in the treatment of pneumococcal meningitis.

In the first installment of this series, Dr. Aaron Zelikovich and Dr. Bhaskar Roy discuss how emerging treatments for myasthenia gravis compare to one another.  Show citation:  McLaren NP, Rosati M, Zhong W, et al. Comparison of the Efficacy and Safety of Myasthenia Gravis Treatments: A Bayesian Network Meta-Analysis. Neurology. 2026;107(3):e218351. doi:10.1212/WNL.0000000000218351  

Dr. Jason Crowell and Ka-Ho Wong discuss national trends in Medicare reimbursement for inpatient neurologic care.  Show citation:  Wong KH, Castillo M, King J, et al. National Trends in Medicare Charges and Reimbursement for Inpatient Neurologic Care, 2013-2023. Neurology. 2026;107(6):e218460. doi:10.1212/WNL.0000000000218460 

In the third episode of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss HSV encephalitis and dexamethasone. 

In part two of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss pegivirus-associated encephalomyelitis. 

In part one of this series, Dr. Paul Crane and Dr. Prashanth Ramachandran discuss acute necrotizing encephalopathy.

In this lab minute, Dr. Stacey Clardy reviews the role of vitamin B12 testing in neurologic practice. 

In part two of this series, Dr. Dara Albert and Dr. Daniel Freedman discuss key unanswered questions in infantile epilepsy and future research priorities.  Show citation:  Freedman D, Babatunde I, Morgan RL, et al. American Epilepsy Society Clinical Practice Guideline: Infantile Epilepsy. Epilepsy Curr. 2026;26(3):174-202. Published 2026 Apr 8. doi:10.1177/15357597261433266  

Dr. Shuvro Roy and Prof. Catherine Jutzeler discussed how age influences neurologic and functional recovery after spinal cord injury and how these findings could inform treatment and future clinical trials.  Show citation:  Pavese C, Scivoletto G, Puci M, et al. The Relationship Between Age and Recovery After Spinal Cord Injury: A Longitudinal Cohort Study. Neurology. 2026;106(2):e214516. doi:10.1212/WNL.0000000000214516    

Dr. Greg Cooper and Dr. Chloe Hill discuss comparing virtual and in-person neurology outpatient visits for new patients. Show citation:  Hill CE, Lin CC, Harris A, et al. Virtual vs In-Person Neurologic Ambulatory Care: A Case-Control Study of Subsequent Health Care Utilization. Neurology. 2026;106(10):e214989. doi:10.1212/WNL.0000000000214989 

In this lab minute, Dr. Stacey Clardy discusses Tolosa Hunt syndrome

Dr. Margarita Fedorova talks with Dr. Sunanjay Bajaj about the Consortium of Neurology Residents and Fellows (CNRF).  Visit the AAN website to learn more about the CNRF.  Connect with the AAN's Consortium of Neurology Residents and Fellows on Synapse. 

Dr. Aaron Zelikovich discusses the efficacy and anthropometric effect of vamorolone with prednisone and deflazacort. Show citation:  Clemens PR, Berglund A, Schiava M, et al. Vamorolone for Duchenne Muscular Dystrophy: A Cross-Trial Efficacy Comparison With Classic Corticosteroids From the FOR-DMD Trial. Neurology. 2026;107(1):e214756. doi:10.1212/WNL.0000000000214756 

In part one of this series, Dr. Dara Albert and Dr. Daniel Freedman share their key takeaways from the recent guideline. Show citation:  Freedman D, Babatunde I, Morgan RL, et al. American Epilepsy Society Clinical Practice Guideline: Infantile Epilepsy. Epilepsy Curr. 2026;26(3):174-202. Published 2026 Apr 8. doi:10.1177/15357597261433266  

Dr. Jessica Ailani and Dr. Serena Orr discuss the genetic risk of migraine and post-traumatic headache in children.  Show citation:  Orr SL, Hershey AD, Kurowski BG, et al. Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study. Neurol Genet. 2026;12(2):e200371. Published 2026 Apr 1. doi:10.1212/NXG.0000000000200371 

Dr. Aaron S. Zelikovich discusses the phase 3 NIMBLE trial of cemdisiran, an siRNA targeting complement component 5, for the treatment of generalized myasthenia gravis.  Show citation:  Vu T, Habib AA, Jacob S, et al. Efficacy and safety of cemdisiran siRNA in myasthenia gravis (NIMBLE): a double-blind, randomised, placebo-controlled, phase 3 trial. Lancet. 2026;407(10540):1712-1725. doi:10.1016/S0140-6736(26)00690-2 

Dr. Zohaib Siddiqi shares clinical pearls on negative myoclonus. 

Dr. Margarita Fedorova discusses the use of troriluzole for spinocerebellar ataxia.  Show citations:  https://www.neurology.org/doi/10.1212/WNL.0000000000209018  https://clinicaltrials.gov/study/NCT06034886  https://clinicaltrials.gov/study/NCT02960893 

Drs. Paul Crane, Fiifi Duodu, and Malya Sahu discuss neuroimmunology and multiple sclerosis diagnosis in Africa, including challenges and efforts to improve care.  Show citation:  Sahu M, Chomba M, Duodu F, Diaz MM, Sokhi D, Saylor D. The Current State of Diagnostics for Neuroimmunological Disorders in Africa. J Cent Nerv Syst Dis. 2025;17:11795735251385319. Published 2025 Nov 19. doi:10.1177/11795735251385319 

Dr. Elizabeth Coon and Dr. Lucy Norcliffe-Kaufmann discuss the mechanism-based therapy with ampreloxetine for neurogenic orthostatic hypotension in multiple system atrophy, highlighting recent clinical trial results and future directions.  Show citation:  Freeman R, Kaufmann H, Biaggioni I, et al. Mechanism-Based Therapy With Ampreloxetine for Neurogenic Orthostatic Hypotension in Multiple System Atrophy: A Randomized Withdrawal Trial. Neurology. 2026;107(3):e218284. doi:10.1212/WNL.0000000000218284 

Dr. Margarita Fedorova explores sex-related differences in the pharmacokinetics of levodopa among levodopa-naïve patients with PD and evaluates their relationships with levodopa-related complications. Show citation:  Conti V, De Bellis E, Corbi G, et al. Sex differences in levodopa pharmacokinetics in early Parkinson's disease: implications on levodopa-related complications. Front Pharmacol. 2026;17:1748932. Published 2026 Apr 7. doi:10.3389/fphar.2026.1748932 

In part two of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the steps to take if you are screening for a psychiatric comorbidity and the results indicate that someone may be positive for depression, anxiety, or another condition.  Show citations:  Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy. Epilepsia. 2022;63(2):316-334. doi:10.1111/epi.17140  Patel AD, Baca C, Franklin G, et al. Quality improvement in neurology: Epilepsy Quality Measurement Set 2017 update. Neurology. 2018;91(18):829-836. doi:10.1212/WNL.0000000000006425  

In the August episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost highlight how the AAN's growing representation within the AMA strengthens the voice of neurology.  Stay informed by watching the President's Spotlight video.  

In part two of this series, Drs. Shuvro Roy, Jiwon Oh, and Amit Bar-Or discuss the results of the FENhance 1 and 2 trials looking at fenebrutinib in relapsing  MS.  For more information, please read about the abstract that was presented at the 2026 AAN Annual Meeting.  Read more about the Fenebrutinib Trial. 

In part one of this series, Drs. Shuvro Roy, Jiwon Oh, and Amit Bar-Or discuss the results of the fenebrutinib trial and highlight the key takeaways that healthcare providers should be aware of.   For more information, please read about the abstract that was presented at the 2026 AAN Annual Meeting.  Read more about the Fenebrutinib Trial. 

In part one of this series, Dr. Halley Alexander and Dr. Heidi Munger Clary discuss the best methods for screening patients with epilepsy in a clinical setting. Show citations:  Mula M, Brodie MJ, de Toffol B, et al. ILAE clinical practice recommendations for the medical treatment of depression in adults with epilepsy. Epilepsia. 2022;63(2):316-334. doi:10.1111/epi.17140  Patel AD, Baca C, Franklin G, et al. Quality improvement in neurology: Epilepsy Quality Measurement Set 2017 update. Neurology. 2018;91(18):829-836. doi:10.1212/WNL.0000000000006425  

In the second episode of this series, Dr. Dara Albert and Dr. Jon Stone discuss the future of FND and the innovative topics presented at the conference. 

In part two of this series, Dr. Stacey Clardy and Dr. John Ney discuss what neurologists should do differently after reading this article.  Show citation: Ney J, Fenton B, Grinberg AS, et al. Association of Military Sexual Trauma With Migraine and Migraine-Related Health Care Utilization Among Post-9/11 US Veterans. Neurol Clin Pract. 2026;16(3):e200618. doi:10.1212/CPJ.0000000000200618  

In the first episode of this series, Dr. Dara Albert and Dr. Jon Stone emphasize the main takeaway from this year's conference that should be taught to residents. 

In the first part of this series, Dr. Stacey Clardy and Dr. John Ney discuss the key clinical messages for all practicing neurologists.   Show citation: Ney J, Fenton B, Grinberg AS, et al. Association of Military Sexual Trauma With Migraine and Migraine-Related Health Care Utilization Among Post-9/11 US Veterans. Neurol Clin Pract. 2026;16(3):e200618. doi:10.1212/CPJ.0000000000200618  

In this lab minute, Dr. Stacey Clardy discusses Susac syndrome and Behçet disease. 

In this lab minute, Dr. Stacey Clardy discusses human prion disease. 

In this lab minute, Dr. Stacey Clardy discusses human prion disease. 

In the July episode of the President's Spotlight, Dr. Jason Crowell and Dr. Natalia Rost provide a mid-year review of the AAN's progress, highlighting advocacy successes and the growing momentum for brain health worldwide.  Stay informed by watching the President's Spotlight video.  

Dr. Derek Stitt and Dr. Jennifer Morganroth discuss why identifying carrier status is so important.  Show citation:  Morganroth J, Yasek J, Harms M. Preparing Amyotrophic Lateral Sclerosis Clinics to Provide Longitudinal Care for Individuals Carrying ALS Risk Variants. Neurol Genet. 2026;12(4):e200406. Published 2026 Jun 24. doi:10.1212/NXG.0000000000200406  

Dr. Justin Abbatemarco and Sukhun Kang discuss seeding trials and other hidden marketing tactics in clinical trials, and their implications for clinical practice and patient care.  Show citation:  Kang S, Lin I, Ekblom M, and Chang S. Clinical trials that are actually marketing ploys targeting doctors – how seeding trials put profit over patients. The Conversation. 2026;6(5). doi:10.64628/AAI.cxdfhnh9s

Dr. Margarita Fedorova discusses the DRAIN trial and the efficacy of acetazolamide in idiopathic normal pressure hydrocephalus.  Show citation:  Virhammar J, Fasth O, Ekblom M, et al. Safety, tolerability, and efficacy of acetazolamide in idiopathic normal pressure hydrocephalus (DRAIN) in Sweden: a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol. 2026;25(6):550-559. doi:10.1016/S1474-4422(26)00126-2 

Dr. Matthew Robbins discusses the assessment and diagnosis of headache in emergency settings, emphasizing red and green flags to differentiate primary from secondary headaches. This episode provides practical tips for trainees and clinicians to improve headache management. Show citation:  Robbins MS. Diagnosis and Management of Headache: A Review. JAMA. 2021;325(18):1874-1885. doi:10.1001/jama.2021.1640  

In the second episode of this series, Dr. Dara Albert and Dr. Scott Perry discuss common barriers to transitioning from pediatric to adult care and share practical strategies clinicians can use to support successful patient transitions. Show citation:  Perry MS, Nascimento FA, Pina-Garza JE, et al. Addressing Barriers to Transitioning Pediatric Patients With Epilepsy to Adult Health Care in the United States: A Narrative Review. Neurol Clin Pract. 2026;16(3):e200616. doi:10.1212/CPJ.0000000000200616 

To celebrate 75 years of Neurology®, Dr. Chris Boes and Dr. José Merino discuss the journal's history, its evolution, and what lies ahead for the future of Neurology®.   Read more about the first 75 years of Neurology®.   

In part one of this series, Dr. Dara Albert and Dr. Scott Perry discuss what every neurology resident should know about caring for young adults with epilepsy as they transition from pediatric to adult neurology. Show citation:  Perry MS, Nascimento FA, Pina-Garza JE, et al. Addressing Barriers to Transitioning Pediatric Patients With Epilepsy to Adult Health Care in the United States: A Narrative Review. Neurol Clin Pract. 2026;16(3):e200616. doi:10.1212/CPJ.0000000000200616 

In this episode, Dr. Jonathan Crowe reviews the Capitol Hill Report from June 22nd, discussing milestones related to the Improving Seniors' Timely Access to Care Act.  Stay updated with what's happening on the hill by visiting aan.com/chr.  Learn how you can get involved with AAN advocacy. 

In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy.  Show citation:  Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi:10.1212/WNL.0000000000214466  Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia. 2025;66(11):4162-4182. doi:10.1111/epi.18574 Krauss GL, Elizebath R, Wheless SSJW, et al. Phase III Trial of EpiWatch for Tonic-Clonic Seizure Detection in Children and Adults. Neurology. 2026;2 (2) e000111. doi:10.1212/WN9.0000000000000111 

In the third part of this series, Dr. Halley Alexander explores emerging trends and recent advances in epilepsy.  Show citation:  Tolchin B, Goldstein LH, Reuber M, et al. Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee. Neurology. 2026;106(1):e214466. doi:10.1212/WNL.0000000000214466  Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia. 2025;66(11):4162-4182. doi:10.1111/epi.18574 Krauss GL, Elizebath R, Wheless SSJW, et al. Phase III Trial of EpiWatch for Tonic-Clonic Seizure Detection in Children and Adults. Neurology. 2026;2 (2) e000111. doi:10.1212/WN9.0000000000000111 

In part two of this series, Dr. Halley Alexander discusses seizure types, epilepsy types, and the etiology of epilepsy.  Show citations:  Beniczky S, Trinka E, Wirrell E, et al. Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy. Epilepsia. 2025;66(6):1804-1823. doi:10.1111/epi.18338  Beniczky S, Trinka E, Wirrell E, et al. A practical guide to the updated seizure classification 2025. Epileptic Disord. 2025;27(6):1087-1104. doi:10.1002/epd2.70110 

Dr. Greg Cooper and Dr. Elisabeth Kurpershoek discuss how clinicians communicate uncertainty during Parkinson's disease diagnosis and how this impacts patient trust and understanding.  Show citation:  Hillen MA, Kurpershoek E, Huisman MHB, et al. Clinician Communication About Uncertainty During Parkinson Disease Diagnostic Consultations. Neurol Clin Pract. 2026;16(3):e200613. doi:10.1212/CPJ.0000000000200613 

Dr. Katie Krulisky and Dr. Marcus Pinto discuss the diagnosis and management of hereditary ATTR amyloidosis. Show citation:  Panrudkevich AH, Jones FJS, Shouman K, et al. Sensitivity of Nerve and Skin Biopsy and Fat Aspirate for Amyloid in Symptomatic Hereditary ATTR Amyloidosis With Peripheral Neuropathy. Neurology. 2026;106(11):e218033. doi:10.1212/WNL.0000000000218033