Out Loud with Dr. Makkani

In this episode of Out Loud, Dr. Makkani is joined by Dr. Aryanna Amini, a board-certified family medicine physician with additional certification in sports medicine and obesity medicine.They talk about what obesity medicine actually looks like beyond the online noise around GLP-1 medications. The conversation covers obesity as a chronic medical condition, the stigma patients carry, realistic expectations with GLP-1s, muscle preservation, strength training, compounded medications, access, nutrition, and why weight alone should not be the only measure of health.They also discuss how social media has shaped the way patients think about weight loss, why many patients feel shame even asking for help, and what more thoughtful, weight-neutral obesity care can look like in real clinical practice.This episode is a grounded physician-to-physician conversation about obesity, GLP-1s, metabolic health, and treating patients without judgment.Dr. Amini's social media: @draryannaaminiDr. Makkani's social media: @drmakkani

GLP-1 medications have changed the way we treat obesity, diabetes, and metabolic disease.In this episode, I talk about compounded GLP-1s, online prescribing, and why the process around these medications matters — including dosing, follow-up, patient selection, and informed consent.This is not a conversation about fear. It is a conversation about treating these medications with the medical oversight they deserve.

Women’s health is finally being talked about more openly and that matters.But somewhere along the way, hormones, cortisol, inflammation, gut health, perimenopause, PCOS, supplements, and “wellness” became one of the biggest industries on the internet.In this episode of Out Loud, Dr. Makkani talks about why so many women have felt dismissed for years, why online health content can feel validating, and how fear-based wellness marketing can turn women’s bodies into another optimization project.Women deserve thoughtful, evidence-based conversations about their health without being dismissed by medicine or manipulated by marketing.Episode 2: When Women’s Health Became a Social Media Industry

Out Loud with Dr. Makkani is a podcast about medicine, wellness, aesthetics, misinformation, and the realities of modern healthcare from the perspective of a board-certified internal medicine physician.Some episodes break down confusing health trends and viral medical claims. Some explore the systems, burnout, and frustrations shaping the way patients experience healthcare today. Others are honest conversations with physicians, creators, researchers, and people working inside health and wellness.This is where evidence-based medicine meets real life.Thoughtful. Grounded. Honest. Human.