PODCAST · science
Out of the Blue: An AJRCCM Podcast
by American Thoracic Society
The Out of the Blue podcast takes you out of the pages of the American Journal of Respiratory and Critical Care Medicine and into the minds of the most brilliant researchers in the fields of respiratory, critical care, and sleep medicine.
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100
Electronic Cigarette Vapor with Nicotine Causes Airway Mucociliary Dysfunction
Maor Sauler is joined by Drs. Samuel Chung, Matthias Salathe, and Mehmet Kesimer to discuss the article “Electronic Cigarette Vapor with Nicotine Causes Airway Mucociliary Dysfunction Preferentially via TRPA1 Receptors
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99
Perspectives on Burnout from Pulmonary, Critical Care, and Sleep Medicine Division Directors
Dr. Michael Lanspa sits down with Dr. Seppo Rinne to discuss burnout from the perspectives of pulmonary, critical care, and sleep medicine division directors.
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98
Best of the Blue in 2019
Join our podcast hosts Nitin Seam MD and John Fleetham MD as they share their thoughts on some of the most interesting papers related to pulmonary, critical care and sleep medicine published in the AJRCCM in 2019.
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97
Supra-Physiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients
Dr. Michael Lanspa sits down with Dr. Edward Palmer to discuss the paper “The Association Between Supra-Physiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients: A Multi-Centre Observational Cohort Study”.
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96
BAL Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications
Dr. Maor Sauler is joined by Drs. Nathaniel Weathington and Brian Modena to discuss the article “BAL Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications”.
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95
Diagnosis and Treatment of Adults with Community-acquired Pneumonia
Dr. John Fleetham is joined by Drs. Metlay and Waterer to discuss the American Thoracic Society and Infectious Diseases Society of America's official clinical practice guideline on diagnosing and treating adults with CAP.
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94
Evaluation and Management of Obesity Hypoventilation Syndrome
Dr. John Fleetham is joined by Dr. Babak Mokhlesi to discuss the recently published ATS Guideline on the evaluation and treatment of OHS.
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93
ATS Conference Issue 2019
Dr. Jadwiga Wedzicha, editor-in-chief of the American Journal of Respiratory and Critical Care Medicine, joins Nitin Seam to discuss several important papers from 5/1/19 Blue Journal.
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92
Long-term Outcome After Prolonged Mechanical Ventilation: A Long-Term Acute-Care Hospital Study
Dr. Trish Kritek is joined by Drs. Jubran and Nava to discuss the paper “Long-term Outcome After Prolonged Mechanical Ventilation: A Long-Term Acute-Care Hospital Study”
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91
Symptom Subtypes of OSA Predict Incidence of Cardiovascular Outcome
Dr. John Fleetham is joined by Drs. Diego Mazzotti and Henry Yaggi to discuss the paper "Symptom Subtypes of Obstructive Sleep Apnea Predict Incidence of Cardiovascular Outcomes".
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90
The Combination of Atomoxetine and Oxybutynin Greatly Reduces OSA Severity
Dr. John Fleetham is joined by Luigi Taranto Montemurro, MD, Andrew Wellman, MD, PhD, and Seva Polotsky, MD, PhD to discuss the impact the combination of Atomoxetine and Oxybutynin has on reducing the severity of obstructive sleep apnea.
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89
The Asthma Issue
Dr. Nitin Seam discusses important papers from the special 2/15/19 AJRCCM asthma issue with deputy editor Dr. Fernando D. Martinez and associate editor Dr. Leonardo Fabbri.
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88
Management of Malignant Pleural Effusion Clinical Practice Guideline
David Feller Kopman and Daniel Sterman join Nitin Seam to discuss the recent Clinical Practice Guideline on Management of Malignant Pleural Effusions published in the 10/1/18 American Journal of Respiratory and Critical Care Medicine.
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87
Determinants of Intensive Care Unit Telemedicine Effectiveness: An Ethnographic Study
Dr. Trish Kritek sits down with Dr. Jeremy Kahn to discuss what organizational factors may impact the clinical effectiveness of ICU telemedicine programs.
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86
Best of the Blue in 2018
Nitin Seam, Trish Kritek and John Fleetham review their favorite podcasts discussions of important articles in AJRCCM in 2018.
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85
Prenatal Household Air Pollution is Associated with Impaired Infant Lung Function
Dr. John Fleetham is joined by Drs. Alison Lee and John Balmes to discuss the article "Prenatal Household Air Pollution is Associated with Impaired Infant Lung Function with Sex-Specific Effects: Evidence from GRAPHS, a Cluster Randomized Cookstove Interv
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84
Mortality Changes Associated with Mandated Public Reporting for Sepsis
Trish Kritek is joined by Dr. Mitchell Levy to discuss his article “Mortality Changes Associated with Mandated Public Reporting for Sepsis: The Results of the New York State Initiative”
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83
Diagnosis of IPF Clinical Practice Guideline Part 2
In Part 2 of this discussion of the 2018 ATS/ERS/JRS/ALAT Guideline, we discuss the approach to invasive procedures in suspected IPF and unanswered questions/directions of future research in IPF.
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82
Diagnosis of IPF Clinical Practice Guideline: Part 1
Dr. Nitin Seam moderates a discussion of the 2018 ATS/ERS/JRS/ALAT Guideline with authors Ganesh Raghu and Kevin Wilson. Part 1 discusses the history, how the guideline questions were formulated and the non-invasive workup.
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81
Alternatives to CPAP When Treating Obstructive Sleep Apnea
Dr. Fleetham is joined by Drs. Julia Chapman and Sanjay Patel to discuss their respective article and editorial on alternatives to CPAP and the role Armodafinil could possibly play.
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80
Effect of Supplemental Oxygen on Blood Pressure in Obstructive Sleep Apnea
John Fleetham is joined by Chris Turnbull, lead author of the paper “Effect of Supplemental Oxygen on Blood Pressure in Obstructive Sleep Apnea (SOX): A Randomised, CPAP Withdrawal Trial”.
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79
Nitric Oxide Decreases Acute Kidney Injury and Stage 3 Chronic Kidney Disease after Cardiac Surgery
Drs. Lorenzo Berra and Mark Gladwin join Nitin Seam to discuss an interesting trial looking at the effect of inhaled nitric oxide on hemolysis and renal failure post cardiac surgery
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78
Reclassifying Acute Respirators Syndromey Distres
Dr. Trish Kritek is joined by Drs. Luciano Gattinoni and Taylor Thompson to discuss Gattinoni’s article on the topic.
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77
Do Endobronchial Valves Improve Outcome in Heterogeneous Emphysema?
Drs. Gerard Criner and Gaetan Deslee join Nitin Seam to discuss the results of the multi-center LIBERATE trial, the first endobronchial valve study to follow patients for 12 months.
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76
Phenotyping Pharyngeal Pathophysiology using Polysomnography in Patients with OSA
Dr. Fleetham discusses phenotyping using polysomnography in patients with COPD with Drs. Scott Sands and David Rappoport
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75
The Conference Issue with AJRCCM Editor Jadwiga Wedzicha
Dr. Wedzicha joins Nitin Seam to give her perspective on 3 important papers from the conference issue of the blue journal and to discuss some current and future articles of interest.
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74
Research Priorities in Pathophysiology for SDB in patients with COPD
Drs. Atul Malhotra and Safwan Badr join Dr. Fleetham to discuss the article “Research priorities in pathophysiology for sleep-disordered breathing (SDB)in patients with chronic obstructive pulmonary disease (COPD)”
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73
Can Nocturnal Dexmedetomidine Prevent ICU Delirium?
Nitin Seam discusses this phase II trial published in the Blue Journal with lead study author Dr. Yohanna Skorbik and Dr. Tim Girard
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72
Efficacy of Cisatracurium Compared to Vecuronium in Patients with or at Risk for ARDS
Dr. Trish Kritek is joined by Dr. Marc Moss to discuss the findings and implications of the article “An Observational Study of the Efficacy of Cisatracurium Compared to Vecuronium in Patients with or at Risk for ARDS”.
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71
Do Borderline Pulmonary Artery Pressures Predict Mortality?
Drs. Gabor Kovacs and Brad Maron join Nitin Seam to discuss “Mild Elevation of Pulmonary Arterial Pressure as a Predictor of Mortality”, a paper Dr. Kovacs' group published in the February 2018 issue of the AJRCCM.
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70
An RCT Of Intensified ICS and LABA At The Onset Of URTI To Prevent COPD Exacerbations
Dr. John Fleetham and Prof. Daiana Stolz, MD, MPH discuss the findings of Prof. Stolz’s paper "Intensified therapy with inhaled corticosteroids and LABA at the onset of URTI to prevent COPD exacerbations".
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69
Best of the Blue in 2017
Please listen to our podcast editors give their thoughts on some of the most interesting papers related to pulmonary, critical care and sleep medicine published in American Journal of Respiratory and Critical Care Medicine in 2017.
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68
Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly
Recent evidence suggests that Obstructive Sleep Apnea (OSA) may be a risk factor for developing Mild Cognitive Impairment and Alzheimer’s disease. Dr. John Fleetham and author Ricardo Osorio discuss.
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67
Effect of Obstructive Sleep Apnea Treatment on Renal Function in Patients with Cardiovascular Disease
Dr. John Fleetham and Dr. Doug McEvoy discuss Dr. McEvoy’s paper on the effect of OSA treatment on renal function in patients with cardiovascular disease.
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66
Timing of Antibiotics and Sepsis Mortality: Does Each Hour Truly Matter?
Dr. Nitin Seam is joined by Drs. Vincent Liu and Mervyn Singer to discuss Dr. Liu's paper "The Timing of Early Antibiotics and Hospital Mortality in Sepsis”
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65
The Voice of Surrogate Decision Makers: Family Responses to Prognostic Information in Chronic Critical Illness
Dr. Trish Kritek discusses the findings of this study with lead author Judith E. Nelson.
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64
Is CT Screening For Lung Cancer Generalizable to Older Patients?
In this podcast, we review a comparison of outcomes in patients 65-74 years old from SEER-Medicare and NLST datasets in stage I lung cancer with study first author, Dr. Nichole Tanner as well as Dr. Neal Navani.
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63
Joblessness and Lost Earnings After ARDS in a 1-Year National Multicenter Study
Disclaimer: audio for this episode is slightly distorted; we apologize for any inconvenience. Dr. Trish Kritek discusses the findings of this study with authors Biren Kamdar and Dale Needham.
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62
Randomized Trial of Liposomal Amikacin for Inhalation in Nontuberculous Mycobacterial Lung Disease
Dr. John Fleetham sits down with Dr. Kennth Olivier to discuss the findings of his paper published in the AJRCCM this past March
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61
Part Two - Clinical Practice Guideline: Mechanical Ventilation in ARDS
In part two of the discussion, Drs. Eddy Fan and Nitin Seam discuss the clinical practice guideline recommendations as well as unanswered questions regarding high PEEP, recruitment maneuvers and ECMO in ARDS.
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60
Part 1-Clinical Practice Guideline: Mechanical Ventilation in ARDS
A conversation between Drs. Eddy Fan and Nitin Seam as they discuss the strong recommendations made in the important Clinical Practice Guideline published on mechanical ventilation in adults with ARDS as well as the areas of controversy or uncertainty.
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59
Obstructive Sleep Apnoea and Retinopathy in Patients with Type 2 Diabetes
Dr. John Fleetham speaks with Dr. Abd Tahrani to discuss his article Obstructive Sleep Apnoea and Retinopathy in Patients with Type 2 Diabetes: A Longitudinal Study.
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58
The Long View and the Fast Lane
Dr. Nitin Seam sits down to talk about the future of the Blue Journal with Editor-in-Chief Dr. Jadwiga Wedzicha and Deputy Editor Dr. Laurent Brochard.
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57
Sleep Disordered Breathing: Still the New Kid on the Block
Dr. John Fleetham sits down with Drs. Ayas and Bhattacharjee to discuss their editorial on sleep disordered breathing.
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56
Critical Care Medicine: A Young, Indispensable and Adaptive Discipline
In celebration of the AJRCCM’s 100 year anniversary, Dr. Trish Kritek sits down with Laurent Brochard to discuss the past, present, and future of critical care medicine.
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55
Physiology and COPD in the Blue Journals
In celebration of the AJRCCM’s 100 year anniversary, Dr. John Fleetham sits down with Dr. Peter Calverley to discuss contributions the blue journal has made to the advancement of physiological research of COPD.
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54
Can We Predict Propensity for Asthma Exacerbation?
Dr. Loren Denlinger and Nitin Seam discuss the results of SARP-3 , a multi-center cohort study of adults and children with severe asthma. Dr. Denlinger describes the factors that were found to predict exacerbation-prone asthma.
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53
Balanced Crystalloids versus Saline in the ICU
Dr. Trish Kritek is joined by Dr. Todd Rice to discuss his article “Balanced Crystalloids versus Saline in the Intensive Care Unit: The SALT Randomized Trial”.
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52
GOLD 2017 Report: What You Need to Know
Blue Journal Editor Dr. Jadwiga Wedzicha joins Dr. Nitin Seam to discuss the newly published 2017 GOLD report. Dr. Wedzicha explains the major updates in the report regarding both diagnosis and management of patients with COPD.
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51
Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes in Pediatric Intensive Care
Host Dr. Trish Kritek is joined by Dr. Punkaj Gupta to discuss the effectiveness of 24/7 in-house coverage on children suffering from critical illness.
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ABOUT THIS SHOW
The Out of the Blue podcast takes you out of the pages of the American Journal of Respiratory and Critical Care Medicine and into the minds of the most brilliant researchers in the fields of respiratory, critical care, and sleep medicine.
HOSTED BY
American Thoracic Society
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