Parkinson's Disease Podcasts by No Silver Bullet

In this special annual review, we are joined by Dr Simon Stott, Director of Research at Cure Parkinson's. Simon shares his key Parkinson’s research takeaways from 2025 and discusses the breakthrough results he is looking for in 2026.If you find our webinars helpful, please Subscribe to NoSilverBullet4PD. By following us, you are helping our community become more visible on the internet. This allows us to reach more people worldwide living with Parkinson’s, giving them the opportunity to access vital expertise and a holistic strategy for managing their condition.00:00 – Introduction05:15 – Dr Simon Stott: Cure Parkinson’s Research Overview 15:30 – 2025 Research Takeaways: Trials and Triumphs 35:45 – Looking Ahead: What to expect in 2026 50:10 – Audience Q&A 01:05:00 – Closing Remarks & Next Webinar AnnouncementWebsites:https://cureparkinsons.org.uk/https://nosilverbullet4pd.comhttps://pdbuddy.app/Follow us on Instagram: @nosilverbullet4pdThis session is for information and education purposes only. If you are seeking medical advice, please consult a medical professional. Full disclaimer details can be found here: https://nosilverbullet4pd.com/disclamer-.html 

Is it possible to repair the brain in Parkinson's disease? In this special webinar, we are joined by Professor Roger Barker from the University of Cambridge to answer that very question.Professor Barker is a global leader in cell-based therapies and a Principal Investigator at the Cambridge Stem Cell Institute. In this talk, he breaks down the science of replacing lost dopamine cells, the history of fetal tissue transplants, and the exciting new era of stem cell trials.He discusses the potential for a "one-off" treatment that could restore dopamine levels to normal, the challenges of past trials, and what the future holds for people living with Parkinson's today.About the Speaker: Professor Roger Barker is a Professor of Clinical Neuroscience and Consultant Neurologist at Addenbrooke’s Hospital, Cambridge. He leads the Stem-PD clinical trial and is a central figure in the global G-Force PD consortium, working to bring stem cell therapies to the clinic.About NoSilverBullet4PD: We are a Parkinson's support group. We believe that while there is no single "silver bullet," there is plenty of "silver buckshot"—tools and knowledge to help us live better.⚠️ MEDICAL DISCLAIMER: This content is for informational and educational purposes only and is not intended as a substitute for professional medical advice. Always consult your physician or specialist regarding your Parkinson's treatment and care.JOIN OUR COMMUNITY: Want more expert insights? Register for our webinars and updates at https://nosilverbullet4pd.com/

Join Beatrice from PD Buddy and Curaleaf UK experts Dr Mark Weatherall and Dr Simon Erridge for a clear and practical discussion on medical cannabis in Parkinson’s care.Interest in medical cannabis is growing among people with Parkinson’s, but so is confusion. Many people with Parkinson's are unsure about what cannabis can help with, how to access it legally, or why some products work while others don’t.  To bring clarity, Beatrice, the founder of the PD Buddy app, invited two specialists from Curaleaf UK for a straightforward discussion focused on real-life concerns: Which symptoms might cannabis help? What’s the difference between medical and recreational products? How do you know what dose or format is right? What are the risks? How does someone begin the process of getting a prescription?Throughout the session, the conversation stays practical and grounded in everyday challenges faced by people with Parkinson’s — sleep, pain, stiffness, and overall quality of life. The goal is not to promote cannabis, but to provide reliable information so people can make safer, better-informed choices.Medical cannabis is regulated very differently around the world. What is allowed, and how it is prescribed, varies widely. Nothing we discuss today should be taken as medical or legal advice, and we encourage everyone to check the rules in their own country, state or region.

In this interview, Beatrice Zatorska, Founder of PD Buddy app sits down with Scott McLeod, co-founder of StrydAR, to explore their groundbreaking Parkinson’s Walking Glasses. These glasses use Visual Cueing technology, inspired by fighter pilot helmets, to help people with Parkinson’s overcome common mobility challenges such as freezing of gait, slowness, and balance issues.We cover everything from how the holographic cue works, what symptoms it targets, and how quickly people notice improvements in walking, posture, and confidence. Scott explains when and how to use the glasses, whether prescription lenses are needed, and what the cost and trial options look like.The conversation also dives into personal stories from users, unexpected benefits like improved confidence and mental well-being, and what’s next for StrydAR — including upcoming trials and new features.If you or someone you know is living with Parkinson’s and struggling with walking or freezing, this interview offers practical insight into an innovative tool designed to make daily life safer and more independent.Please note that this session is for informational and educational purposes only. If you are seeking medical advice, please consult a qualified healthcare professional.👉 Learn more about StrydAR: https://www.parkinsonswalkingglasses.... 👉 Download PD Buddy App for free: https://pdbuddy.app/

We were delighted to host Dr Briana De Miranda on the topic of "How the environment affects Parkinson's Disease and what you can do about it."As Parkinson's diagnoses continue to rise worldwide, increasing attention is being given to the role of environmental factors in the disease's onset and progression, and to the practical steps we can take to better protect ourselves from these risks.Briana De Miranda, Ph.D., is a Neurotoxicologist and Associate Professor of Neurology in the Killion Center for Neurodegeneration at the University of Alabama at Birmingham. Her research focuses on environmental risks for neurodegenerative diseases, integrating expertise in toxicology, pharmacology, and neuroscience. Her interdisciplinary research is aimed at understanding how neurodegeneration is caused by environmental exposures, and finding ways to treat or prevent neurologic disorders caused by toxic risk factors.More about the speaker:-https://scholars.uab.edu/16563-briana-de-mirandahttps://www.parkinson.org/living-with-parkinsons/stories/briana-de-mirandahttps://www.linkedin.com/in/briana-de-miranda-3196a231https://www.sciencedirect.com/science/article/pii/S0969996121000619

We were delighted to host Carl Beech, the creator of the Beech Band, a new wearable device to manage Parkinson’s symptoms.Carl was 51 when he was diagnosed with Young-Onset Parkinson’s.  He began to experience slurring and a rapidly worsening stammer. Faced with the loss of speech, he nearly gave up hope. But then, while experimenting with a therapeutic tapping technique, he had a personal breakthrough – rhythmic tapping allowed him to regulate his speech and relieve his stammer. This led to an idea: what if this could be turned into a wearable device that could help many more people?Today, Carl will be sharing his experience with the Beech Band. After 13 months of wearing the device Carl has experienced remarkable changes to his symptoms. Since its release in July over 15,000 have been sold and there have been very positive reactions from user. Whilst this story is inspiring and hopeful,  it’s important to remember that Parkinson’s is complex, and no single approach works for everyone and that the positive responses are anecdotal. The Beech Band is a wellness device, not a medical treatment, so please speak with your medical team if you have any concerns about using the device or are considering any changes to your medication.More information on the device can be found here:-https://www.beechband.com/https://www.facebook.com/p/BeechBand-61563836532593/https://www.instagram.com/beechband/?hl=enhttps://www.tiktok.com/@beechband

We are delighted to once again host Dr. Matthew Phillips, who presented on:"Optimising Parkinson’s: Essential Therapies".Matt joined us first back in Feb 2023 when he presented "Intermittent Fasting & Keto & Diet Strategies" which has had over 100,000 views since and can still be watched on our YouTube channel https://www.youtube.com/@nosilverbullet4pd998/videosIn this new session, Dr Phillips will offer a broader framework to help people with Parkinson’s navigate and combine various therapeutic options, going well beyond the fasting and ketogenic protocols explored in his previous talks. 

We are delighted to share this update from Dr Sackner-Bernstein, following his previous webinar titled “Why I Am Optimistic That We Might Have a Silver Bullet for PD.”In this new update, he builds on the key ideas from his earlier presentation and shares the latest developments that continue to fuel his optimism.Dr Sackner-Bernstein is the author of a 2021 peer-reviewed study published in The Journal of Parkinson’s Disease, where he proposed that the standard treatment approach to Parkinson’s might actually be the opposite of what is most effective. We had the pleasure of hosting him last year, and we’re excited to hear his latest insights.If you’d like a deeper dive into this topic, you can find our full conversation from June last year on our YouTube channel.Please note: This content is for informational and educational purposes only. For medical advice, please consult your healthcare provider.Thank you,The No Silver Bullet Team

We are delighted to share with you our latest recording  featuring Dr. Alfonso Fasano, a world-renowned neurologist and researcher, presenting “New Allies Against Parkinson’s: Adaptive DBS & Subcutaneous Foslevodopa”.🌟 What to ExpectThis webinar will explore two groundbreaking treatments that are changing the landscape of Parkinson’s care:Adaptive Deep Brain Stimulation (aDBS): Learn how this technology personalizes stimulation in real time to better manage symptoms and reduce side effects.Subcutaneous Foslevodopa: Discover how this new delivery method could offer smoother and more continuous relief from motor fluctuations, potentially replacing traditional oral medications.👨‍⚕️ About the SpeakerDr. Alfonso Fasano is a neurologist specializing in movement disorders, with roles in both Italy and Canada. He is Professor of Neurology at Humanitas University and Head of Neurology at Humanitas Research Hospital in Milan. He also holds a professorship in the Department of Medicine (Division of Neurology) at the University of Toronto and is a staff neurologist at Toronto Western Hospital and the Hospital for Sick Children.Dr. Fasano’s main research interests include using advanced technologies—such as infusion pumps and brain stimulation—to treat Parkinson’s disease, tremor, and walking disorders. He has published over 500 scientific articles, and serves on the editorial boards of leading journals in neurology and movement disorders. He is also actively involved in clinical trials and international research groups.

"Women’s Health & Parkinson’s", a special webinar in collaboration with the PD Buddy App in now available as a PodcastThis session explores the connection between menopause, hormones, and Parkinson’s, providing valuable insights and practical strategies to help you navigate these changes.Led by Dr. Tanya Denne, ND, a naturopathic doctor and researcher, the webinar covers key topics such as hormone replacement therapy (HRT), fatigue, nutrition, gut health, and more. Through evidence-based approaches and real-world case studies, Dr. Denne bridges the gap between neurology, primary care, and holistic wellness—offering tangible takeaways to help you optimise your health and care plan.This event is brought to you in partnership with the PD Buddy App (https://pdbuddy.app/ a free digital tool designed to support people with Parkinson’s and their caregivers. PD Buddy helps you organise routines, track symptoms, and access expert resources, making it easier to manage day-to-day life with Parkinson’s.If you have questions following this webinar, please do not hesitate to contact Dr Denne on:[email protected]

We were delighted to welcome Dr. Wayne Markman, CEO of SYMBYX, for an insightful update on the latest clinical trials using light therapy to ease Parkinson’s symptoms. SYMBYX stands out for its strong focus on evidence-based innovation, investing significantly in medical research to better understand and validate the role of light therapy in Parkinson’s care.For a deeper dive into the science and potential benefits, check out our earlier interview with Dr. Markman from November 2023 on our YouTube channel.This session is intended for informational and educational purposes only. If you're seeking medical advice, please consult a healthcare professional.

Thank you to Prof Malu Tansey who joined us to share her expertise on the topic of "Inflammation and Parkinson's and what we can do about it"This presentation was excellent and we encourage you to watch it and the Q&A that followed as you will certainly come away with a better understanding of this complicated topic.About the Speaker:-Malú Gámez Tansey, Ph.D., is a Professor of Neurology and the James Caplin Chair in Alzheimer’s Disease at Indiana University School of Medicine and Director of Neuroimmunology Research Group & Executive Associate Director of Education at the Stark Neuroscience Research Institute.Her lab focuses on the role of inflammation and immune system responses in brain health and neurodegenerative disease, with particular focus on central-peripheral neuroimmune crosstalk and the gut-brain axis, with the long-term goal of developing better therapies to prevent and/or delay these diseases.Dr. Tansey obtained her B.S/M.S in Biological Sciences from Stanford University and her Ph.D. in Cell Regulation from UT Southwestern, followed by post-doctoral work in neuroscience at Washington University. She returned to academia as an Assistant Professor of Physiology at UT Southwestern in 2002 and was recruited to Emory University School of Medicine as a tenured Associate Professor in 2009. After 10 years at Emory and rising to the rank of Full Professor, in 2019, she was recruited to the Department of Neuroscience in the College of Medicine at the University of Florida as the Fixel Chair in Neuroscience and Neurology and Director of the Centre for Translational Research in Neurodegenerative Disease. She also served on the executive committees for the McKnight Brain Institute and the Fixel Institute for Neurological Diseases.

We recently hosted two webinars on Mucuna pruriens, a tropical legume rich in levodopa. The first, with Dr. Roberto Cilia, focused on the use of Mucuna in low-income countries where levodopa is often unavailable or unaffordable. The second, with Dr. Rafael Maldonado, took a broader perspective. Due to continued interest and questions on mucuna, we organised today’s session with Dr. Tanya Denne.Since 2010, Dr. Denne has researched Mucuna for its potential in treating Parkinson's.  Having been mentored by Dr. Laurie Mischley, she chose her Naturopathic Medical School with a focus on serving the Parkinson's community.Dr. Denne treats the whole person with a personalized, holistic approach and specializes in optimizing care plans and addressing treatment gaps. Driven by her passion for public health, she joined Dr. Roberto Cilia in Ghana in February to help tackle Parkinson's care in countries where Mucuna is sometimes all they have. This session is intended for informational and educational purposes only. If you're seeking medical advice, please consult a healthcare professional. For those who are new to us, “No Silver Bullet” is managed by Mark Limebear and myself, with the goal of sharing valuable Parkinson's expertise.Our mission is to empower you with knowledge and motivation to make informed choices about adapting your lifestyle to manage your symptoms and slow disease progression.We also share recordings of our webinars on YouTube and Spotify. You can find the details on our website: nosilverbullet4pd.com.If you have questions following this webinar, please do not hesitate to contact Dr Denne on:[email protected]

We are delighted to share with you our latest recording "A new Parkinson's test- hope or hype?" a webinar on the alpha-synuclein seed amplification assay (αSyn-SAA), presented by the M J Fox Foundation as a significant breakthrough in the search for a Parkinson's biomarker.With the growing interest surrounding αSyn-SAA, it’s crucial for patients and their families to understand both its potential benefits and limitations.About the Speaker:-Dr. Alberto Espay is Professor and Endowed Chair of the James and Joan Gardner Center for Parkinson's Disease at the University of Cincinnati.He has published over 300 research articles and 8 books, including Common Movement Disorders Pitfalls, which received the Highly Commended BMA Medical Book Award in 2013 and Brain Fables, the Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer them, co-authored with Parkinson's patient and advocate Benjamin Stecher, selected by the Association of American Publishers for the PROSE Award honouring the best scholarly work in Neuroscience published in 2020.With colleagues at the University of Cincinnati, he recently launched the first biomarker study of aging (CCBPstudy.com), designed to match people with neurodegenerative disorders to available therapies from which they are most biologically suitable to benefit, regardless of their clinical diagnoses.

Join us for a deep dive into the sleep challenges faced by Parkinson's patients and the potential solutions with Prof S Overeem!Prof. Overeem is a distinguished clinical somnologist and sleep researcher renowned for his expertise in sleep medicine (he was recommended to us by Prof. Bas Bloem). He practices at the Center for Sleep Medicine Kempenhaeghe in the Netherlands, a leading institution dedicated to diagnosing and treating sleep disorders. His clinical focus encompasses a wide range of somnological conditions, with particular interests in narcolepsy, hypersomnias, parasomnias, and sleep disorders associated with Parkinson’s disease.In 2015, he became a senior researcher at Eindhoven University of Technology where he established a pioneering research program aimed at developing innovative diagnostic methods for sleep and its related disorders. He was appointed full professor in June 2017, solidifying his role as a leader in the field.Outside of his professional pursuits, Prof. Overeem enjoys exploring the depths of the ocean and the expanses of the sky, indulging his passions as an avid scuba diver and private pilot.

We are delighted to share with you our presentation by Dr. Rafael Maldonado, and expert on Mucuna, seen by a growing number of PwP as a credible support for Pharmaceutical Levodopa and potentially an alternative for some. Remember, you must consult with your own Medical team before changing or starting any new medication of any type.Dr. Rafael González is a renowned neurologist in Granada with more than four decades of medical experience. He is a renowned specialist who combines clinical practice with teaching as an associate professor at the University of Granada. His extensive training includes an Honorary Research Fellow at the Royal Free Hospital in London and a PhD in Medicine from the University of Granada. He is an expert in Parkinson's, Alzheimer's, headaches, memory loss, epilepsy, stroke and gait disorders.During his extensive and successful professional career, Dr Prof. González Maldonado has treated numerous patients in prestigious medical centres and hospitals. In addition, he is the author of various books on neurological pathologies such as Parkinson's, as well as numerous essays and other medical publications. In 2017, he was the winner of the Top Doctors Awards, which rewards the most valued medical professionals in the private sector.Currently, he works as a neurologist in a private Neurology practice in Granada, the Neuroconsulta Clinic. In addition, it also serves patients from all over the world thanks to online consultations

Dr Simon Stott gives us his inciteful annual review of the main PD research takeaways from 2024 and the research results he will be looking for in 2025.Dr Stott is the Director of Research at Cure Parkinson's. The trust is an international supporter of both lab- and clinic-based research on Parkinson's and aims to find treatments that will slow, halt or reverse the condition.Originally from New Zealand, Simon has more than 20 years of experience in the field of Parkinson's research - in both the academic and biotech sectors. He has been involved in lab-based research as well as clinical studies.He also maintains the 'Science of Parkinson's' website (www.scienceofparkinsons.com), which attempts to explain in plain English the research currently being conducted on Parkinson's.Cure Parkinson's trust:-https://cureparkinsons.org.uk/IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...Want alerts for future speaker sessions? Email us at [email protected] can follow us on social mediaInstagram:-    / nosilverbullet4pd   Twitter:-   / nsb4pd  TikTok   / nosilverbullet4pd  

Dr Dorsey is one of the World's leading experts on PD and delivers his expertise in a very refreshing direct no nonsense way.Dr Ray Dorsey is a professor of neurology and director of the Center for Human Experimental Therapeutics at the University of Rochester Medical Center. He is working to identify and eliminate the root causes of Parkinson's disease. He is co-author of the book, "Ending Parkinson's Disease" in which he, Bas Bloem, Michael Okun and Todd Sherer lay out a plan to help prevent Parkinson's and improve care and treatment.He has just announced the publication of "The Parkinson's Plan" co written with Dr. Michael Okun and available for pre order, just email  [email protected] for a linkDr. Dorsey is investigating new treatments for movement disorders and is working on ways to improve the way care is delivered for individuals with Parkinson's disease and other neurological disorders. Using simple web-based video conferencing, he and his colleagues are seeking to provide care to individuals with Parkinson's disease.

It’s time to reframe our thinking and take a new approach to Parkinson's disease! Despite 200+ years of effort, we do not have a system to predict, prevent, halt, or reverse Parkinson’s. Dr Mischley explores the notion that the problem lies in the lens through which we’ve been viewing it, the approaches we’ve been taking, and the assumptions we’ve been making.Provider bias: Dopamine has been a distraction and obstacle for disease-modification research. Subjective measures are better in early PD.Industry bias.Floor effects for crude measurement systems: Phase 3 studies keep failing because the tools we’ve been using to determine severity aren’t sensitive in newly-diagnosed people in disease-modification research studies. Study designs are flawed. People that enroll in studies probably not same as global population.Providers’ opinion that Parkinson’s is “irreversible and progressive” is outdated and contributes to the problem."What works” and “what providers know how to teach” and “what insurance will pay for” are often not aligned.The systems - and access to the systems - play a role in determining outcomes.We already have tools to make Parkinson’s preventable and reversible that we’re not using.This revised patient-centered, evidence-based pragmatic paradigm will include education, symptom tracking, goal-setting, counseling, laboratory tests to screen for nutritional deficiencies, counseling regarding diet, daily physical activity, social health, and strategies to encourage financial stability.About the speaker:-Dr. Laurie Mischley, ND PhD MPH studied naturopathic medicine (ND) at Bastyr University and epidemiology (MPH) and nutritional sciences (PhD) at the University of Washington and she maintains appointments at both Universities. Her work is focused on identifying the nutritional requirements unique to individuals with Parkinson’s Disease (PD) and has published on coenzyme Q10, lithium, NAD+, and glutathione deficiency (www.lauriemischley.com). She is Principal Investigator of the Modifiable Variables in Parkinsonism (MVP) Study (https://mvp-study.com/), which is attempting to describe why some people with PD progress slower than others. She is working on ways to study, package and deliver evidence-based lifestyle modification as a therapeutic strategy. She founded:-The Parkinson Center for Pragmatic Research (https://parkinson-cpr.com/) The Canine scent-based PD screening tool, ParK-9 (https://park-9.com/), Developed a patient-reported outcome measure to assess PD severity (https://pd-symptoms.com/), built the Parkinson Symptom Tracking (PRO-PD) App, which is available free on iSO or AndroidIs instructor of the online series, Parkinson School (https://www.parkinson-school.com/) for which she has kindly given our No Silver Bullet community  free access for a limited time using the code NOSILVERBULLET

Dr Roberto Cilia spoke to us on the topic of  "Mucuna Pruriens and the future of Parkinson's care in low income countries"There is much discussion by PwP as to the benefits of using this "natural " form of Levadopa as an alternative or in addition to prescribed Levadopa so it is very interesting to hear this presentation and the answers to the very high number of questions in the Q&A that follows it.Roberto's main focus is on using mucuna to treat Parkinson's patients in countries where levodopa is either not available or not affordable. This is a great opportunity to learn about this important legume!Dr. Roberto Cilia is a renowned movement disorder specialist based in Milan, Italy. With extensive experience in neurology, he has dedicated his career to improving the lives of patients suffering from Parkinson's disease and other movement disorders.

We are delighted to be able to share with you our latest interview with Dr Filip Scheperjans who shared with us his fantastic work on "The importance of the gut-brain axis in Parkinson's" which was followed by an excellent Q & A session. More about our expert:-Dr. Filip Scheperjans is a leading expert in neurology, specialising in treating Parkinson’s disease and focusing on advanced methods and gastrointestinal symptoms.He earned his Licentiate of Medicine from the University of Düsseldorf in 2006 and completed his Neurology specialisation at the University of Helsinki in 2013. In 2008, he received his Doctor of Medical Science, focusing on neuroanatomy, and became Associate Professor in 2020 at the University of Helsinki.Dr. Scheperjans investigates the relationship between gastrointestinal symptoms and the microbiome in Parkinson’s disease, exploring novel treatment strategies. His work includes advanced therapies like drug infusions and deep-brain stimulation, supported by major organisations such as the Academy of Finland and the Michael J. Fox Foundation.

Prof Sonia Gandhi joined us to share her expertise on how Mitochondria affects PD with an excellent presentation followed by a very probing Q&A by our well informed audience.Prof Gandhi is a leading expert in the process of protein misfolding, in which smaller proteins, monomers, join together to form larger proteins, oligomers, and how this process may drive organellar dysfunction and cell toxicity in neurodegeneration.Sonia obtained a BA in Neuroscience at Trinity College, University of Cambridge, in 1996, and completed her degree in Medicine at New College, University of Oxford, in 1999. She trained in postgraduate medicine at the Hammersmith Hospital, Royal Brompton Hospital, National Hospital for Neurology and Neurosurgery, and Whittington Hospital. Sonia was awarded a Wellcome Clinical Research Training Fellowship to complete a PhD in Neuroscience at UCL Institute of Neurology in 2004. In 2007, she trained as a Specialist registrar in Neurology, and took up an NIHR Lectureship in Neurology at Imperial College in 2009. In 2012 she was awarded a Wellcome Trust Intermediate Clinical Fellowship, and established her laboratory at the UCL Institute of Neurology in October 2013. She was awarded a laboratory secondment to the Francis Crick Institute in 2016

We had the pleasure of a presentation by Dr Jonathan Sackner-Bernstein, MD, on the topic of "Why I am optimistic that we might now have a Silver Bullet for Parkinson's", followed by a Q&A session of almost 50 probing questions from our audience.Dr. Jonathan Sackner-Bernstein is transforming the treatment of Parkinson’s disease (PD). First, he discovered that the brain cells (dopaminergic neurons) in Parkinson’s patients are exposed to excess dopamine, reaching toxic levels. Next, he identified a drug that reverses disease pathology by reducing dopamine levels in 10 studies using laboratory models of PDAs an academic physician, Sackner-Bernstein leverages lessons learned at the US Food and Drug Administration (where he received 2 Commission’s Awards) and the US Defense Advanced Research Projects Agency (in a central role for the launch of the US Biological Technologies Office with its initial focus on neurotechnology).Jonathan’s history of identifying contrarian views is remarkable for consistently being proven correct by subsequent studies and analyses. His optimism that PD will be conquered by reducing dopamine is supported by scientific data. And this drug therapy is poised to enter Phase 2 clinical trials, with data as soon as 6 months following trial launch.More about the speaker:-Dr Sackner-Bernstein is soon to launch a Blog to provide updates so please register here https://www.parkinsonsdisease.blog/A new website has also been launched by Dr Sackner-Bernstein on which you will see his distinguished team including two of our previous speakers, Prof Roger Barker who spoke o Cell replacement therapy and Dr Lorraine Kalia more recently sharing her expertise on Drug replacement so take moment to watch those recordings here on our channel or listen to them on Spotifyhttps://www.rightbrainbio.com/

We had the pleasure of interviewing Dr Michael Okun on the topic of "Practical strategies for living a happier life with Parkinson's".Dr Okun is a worldwide recognised leader on Parkinson’s disease, is the distinguished Professor of Neurology and Director of the Norman Fixel Institute for Neurological Diseases at the University of Florida Health. The UF institute he co-founded with Kelly D. Foote, M.D. is a one-stop patient-centred clinical-research experience for national and international patients seeking care.Dr. Okun has served as the National Medical Director/Advisor for the Parkinson’s Foundation since 2006. His research has been wide ranging and he is best known for his exploration and innovation in neuromodulation and deep brain stimulation. He has published over 600 peer-reviewed articles and his book, “Parkinson's Treatment: 10 Secrets to a Happier Life” was translated into over 20 languages. His most recent books are “Ending Parkinson’s Disease” and “Living with Parkinson’s Disease”. Dr. Okun was recognized in a 2015 White House ceremony by the Obama administration as a Champion of Change for Parkinson’s Disease

We were delighted to host Dr Michelle Sexton who presented on the topic of  "How can medical cannabis help people with Parkinson's" and here is the recording of the event.About the speaker:-Dr. Sexton is an integrative medicine specialist and respected pioneer in the field of medical cannabis. She has over thirty years of experience as a midwife, herbalist, and naturopathic doctor. She completed a postdoctoral fellowship at the University of Washington in the Departments of Pharmacology/Psychiatry and Behavioural Sciences. There, she studied the endocannabinoid system and its roles in neuro-inflammation and neuro-degeneration. To find out more about Michelle here:-Website :-  https://www.ecsdoctor.com/Website for scheduling a patient consultation is https://www.msextonnd.com/Instagram :-   / dr.michellesexton    (@dr.michellesexton) Facebook:    / msextonnd  Michelle's latest book can be found here :- https://shop.ingramspark.com/b/084?U0...IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform etc , in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted....

We were delighted to host Prof Christine Klein who talked to us about "The importance of genetics in finding a cure for Parkinson's".It was a really interesting presentation and followed by a very good Q&A with excellent questions from you our audience, so thank you.It is now a very worthwhile Podcast and video (on our YouTube Channel https://www.youtube.com/channel/UCN2A0vGOY6j13Ed1rV64gPQ/featured ) to help understand more about this important topic.About the speaker:-Christine Klein is a professor of neurology and neurogenetics. She studied medicine in Hamburg, Heidelberg, Luebeck, London, and Oxford before moving to Boston from 1997 to 1999 for a fellowship in molecular neurogenetics. She completed her neurology training at Luebeck University in 2004, followed by a series of summer sabbaticals in movement disorders in Toronto, Canada in 2004 to 2015. Her research has focused on the clinical and molecular genetics of movement disorders and its functional consequences. In 2009, Dr. Klein became director of the newly founded Institute of Neurogenetics in 2013 in Luebeck, Germany.Prof. Klein has published more than 500 scientific papers. She is deputy editor of ‘Movement Disorders’ and associate editor of ‘Annals of Neurology’ and serves as acting past president of the German Neurological Society. Ten of her former mentees have been promoted to the level of assistant, associate or full professor.Find out more about Christine and her great work here:-https://www.neurogenetics-luebeck.de/...https://www.michaeljfox.org/researche...https://www.youtube.com/watch?v=6xVPl...https://www.youtube.com/watch?v=zDkaJ...https://www.linkedin.com/in/christine...

We are excited to share our latest interview with you all, in which Dr Raul Martinez- Fernandez explains the therapy of Focused Ultrasound, a therapy that offers appropriate candidates with an alternative to the more intrusive DBS. It is of course not a replacement for DBS, simply an alternative offering a solution for those with differing symptoms.More about Dr Martinez-Fernandez:-Dr Raul Martinez-Fernandez is a neurologist and clinical researcher, Associate Professor of Medicine at the Neuro research Centre HM CINAC; HM Puerta del Sur Hospital; CEU San Pablo University, Spain.After getting his neurology diploma in Spain in 2008, he trained at the Deep Brain Stimulation department of the National Hospital of Neurology and Neurosurgery – Queen Square (London). Subsequently, he attended a 2-year fellowship in Grenoble (France), the birthplace of modern Functional Neurosurgery, under the wings of Professors Paul Krack and Elena Moro. In Grenoble, he started his PhD in Medical Science that he obtained in 2017. Since 2015 he is coordinator of the high intensity focused ultrasound program in HM CINAC (Madrid), directed by Prof Obeso.He has published several papers on the topic of focused ultrasound in Lancet Neurology and The New England Journal of Medicine. The experience gathered has allowed him to be invited for lecturing worldwide, to provide support to teams which are starting to use the technique, and to receive several research awards.

We are delighted to host Dr. Simon Stott again in what is becoming our regular start to the year's presentations. And what better way than to hear Dr. Stott's main PD research takeaways from 2023 and research results he will be looking for in 2024.For those of you who are unfamiliar with Dr. Stott's work, Dr Stott is the Director of Research at Cure Parkinson's. The trust is an international supporter of both lab- and clinic-based research on Parkinson's and aims to find treatments that will slow, halt or reverse the condition.Originally from New Zealand, Simon has more than 20 years of experience in the field of Parkinson's research - in both the academic and biotech sectors. He has been involved in lab-based research as well as clinical studies. He also maintains the 'Science of Parkinson's' website (https://scienceofparkinsons.com/about/), which  explains in plain English the research currently being conducted on Parkinson's.IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform and our Podcast hosting platform so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...Want alerts for future speaker sessions? Email us at [email protected] can follow us on social mediaInstagram:-  https://www.instagram.com/nosilverbul... Twitter:- https://twitter.com/NSB4PDTikTok https://www.tiktok.com/@nosilverbulle...

Light Therapy is an area of great interest and hope for PwP worldwide, as shown by the viewing numbers for our 3 previous NSB4PD sessions over the last 48 months.Here in this interview with  Dr Wayne Markman, CEO of SYMBYX, we explore how photobiomodulation devices directly address the gut, vagus nerve and brain. SYMBYX's mission is to develop medically approved light therapies to reduce chronic Parkinson’s symptoms - early trials and clinical data show improvements across a range of symptoms and with a very high safety profile. SYMBYX are committed to increasing clinical trial evidence supporting light therapy as a complementary and effective intervention that fits into a person with Parkinson's medication, healthy diet and exercise regime.About the speaker:-Dr. Wayne Markman is South African-born and emigrated to the US in 1986 and then to Australia in 2000. Dr. Markman obtained a BA in Economics from Macalester College in 1991 and an MBA from Harvard University in 1996; worked as an investment banker, he decided to pursue a career in medical science at Macquarie University in Sydney, specialising in neuroscience and movement disorders.Dr. Markman worked in a physiotherapy clinic before founding SYMBYX, a company dedicated to developing light therapy devices to alleviate the impact of chronic conditions like Parkinson's.He has been personally affected by PD with several close family members diagnosed previously, so this research has added meaning and focus for himWith a focus on the gut-brain axis, SYMBYX is committed to providing complementary and effective interventions for Parkinson's patients worldwide.By next year, SYMBYX will have completed 4 clinical trials with publications in leading peer reviewed journals and commenced 3 additional large scale randomised control trials investigating motor, non-motor and medication efficacy implications of infrared laser treatment to the gut.This is SYMBYX's website :- https://symbyxbiome.com/IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform so that we can share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-hhttps://www.paypal.com/donate/?hosted...If you want to join our mailing list for future speaker sessions then please email us at [email protected]

Annelien and Richelle delve into a topic that is often overlooked, but holds great importance for them as female Parkinson's Disease (PD) advocates. They shed light on how Parkinson's impacts a woman's life, focusing on the various hormonal stages and how they can affect symptoms and the effectiveness of medication. They bring attention to the challenges of coping with a Parkinson's diagnosis in the face of stigma. Moreover, they discuss the significance of considering sex and gender in treatment and research, emphasizing the need for women to advocate for themselves in order to improve their care and raise awareness among other women. This discussion is open to anyone who identifies as a woman, as well as those who care for PD women, including care partners, family members, health professionals, and researchers working in the field of Parkinson's.Richelle Flanagan is a registered Dietitian and was diagnosed with YOPD shortly after the birth of her second child. She is an ambassador for the World Parkinson Congress in Barcelona, 2023. She is particularly passionate about two areas (1) the importance of diet for PD and (2) the unmet needs of women with PD. She is a co-founder of the Women’s Parkinson’s Project (www.womensparkinsonsproject.com) and co-founder of a digital health start-up (My Moves Matter ; www.mymovesmatter.com), a digital self-care companion to empower people with Parkinson’s to live better lives.Dr. Annelien Oosterbaan is 40 years old and got diagnosed with YOPD 7 years ago. She is a proud mother of 4 children and lives in Rotterdam, the Netherlands. She noticed a cyclic pattern in her PD symptoms and when preparing for her last pregnancy she found out there is such a huge lack of knowledge concerning the hormonal impact on PD symptoms. She made it her personal mission to fix this gender gap and started her research project called 'Women and PD' at the Radboudumc Nijmegen (NL). She just launched the online registry for pregnancy and PD, www.pregspark.com, and is one of the authors of the booklet 'In her shoes' (www.yopdwomen.com).

Some of the most promising disease modifying therapies being developed at the moment are based on drug repurposing (eg Exenatide/Ambroxol), making this webinar essential for anyone suffering from Parkinson's or caring for someone suffering from Parkinson's.Dr Lorraine Kalia shares with us her expertise and brings us up to date with the latest news.Dr. Lorraine Kalia is an associate professor and a clinician-scientist at the University of Toronto in Canada. She is dedicated to Parkinson's disease, both in her clinical practice as a movement disorders neurologist and in her research program as a neuroscientist.She is the co-editor-in-chief of the Journal of Parkinson’s Disease and co-chair of the International Parkinson and Movement Disorder Society Scientific Issues Committee.Her research focuses on understanding the fundamental molecular processes that lead to neurodegeneration in Parkinson’s disease and finding new therapies that can target these molecular culprits to slow down or even stop the disease.Dr. Kalia recently presented at the World Parkinson's Congress in Barcelona.More can be found out about the speaker here:-https://lmp.utoronto.ca/faculty/lorra...Website https://kalialabs.org/To find out the latest trails if you are based in or around Toronto Email [email protected]

We are delighted to welcome back the CEO and Founder of Charconeurotech to tell us more about the CUE1 device to help with Parkinson's symptomsCharco Neurotech, the company behind CUE1, was founded by CEO Lucy Jung and named after Professor Charcot, who discovered the therapeutic effects of vibratory stimulation on Parkinson's in the 19th century. Since then, numerous studies have been conducted on the ability of stimulation to alleviate movement symptoms associated with the disease.CUE1 combines the principles of focussed vibrotactile stimulation and cueing, both of which have been scientifically proven to improve motor performance and reduce freezing of gait in people with Parkinson's. The company's testing has demonstrated clinically significant improvements in motor symptoms, including smoother walking and movement, and better fine motor task performance.https://charconeurotech.com/CUE1 combines the principles of focussed vibrotactile stimulation and cueing, both of which have been scientifically proven to improve motor performance and reduce freezing of gait in people with Parkinson's. The company's testing has demonstrated clinically significant improvements in motor symptoms, including smoother walking and movement, and better fine motor task performance.CUE1 is already being used by around 1,000 people in the UK and Addenbrooke's Hospital in Cambridge, UK, has recently begun trialling the device with its inpatients, as reported in this news article:https://www.cuh.nhs.uk/news/high-tech...To add your name to the waiting list use this link:- https://charconeurotech.com/register-...IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted....

Dr. Peter Tass from Stanford Medical School talks to us about “The Parkinson's glove & Vibrotactile fingertip stimulation to ease Parkinson’s symptoms”. A very very interesting device currently being trialed in the USA, with huge potential to dramatically improve the lives of many with PDAbout the Speaker:-Peter Tass studied medicine (MD, Ulm and Heidelberg Univ., Germany), physics (PhD, Stuttgart Univ., Germany), and mathematics (diploma, Stuttgart Univ.) and made a Habilitation in physiology (RWTH Aachen University, Germany).Since 2017 he is Professor of Neurosurgery in the Department of Neurosurgery, Stanford University Medical School. Peter Tass investigates and develops neuromodulation techniques for understanding and treating neurologic conditions such as Parkinson’s disease, epilepsy, dysfunction following stroke and tinnitus. He creates invasive and non-invasive therapeutic procedures by means of comprehensive computational neuroscience studies and advanced data analysis techniques.Peter Tass has published more than 170 peer-reviewed papers, is inventor or co-inventor on more than 270 patents and received a number of national and international awards.Stanford lab homepage: https://med.stanford.edu/tass-lab.htmlYou can follow us on social media:-Please also visit our new website: nosilverbullet4pd.com/Instagram:-https://www.instagram.com/nosilverbul...Twitter:- https://twitter.com/NSB4PDTIKTOK https://www.tiktok.com/@nosilverbulle...IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...

If you want to know where to start in addressing your PD symptoms then this is the place and the video to start with. Dr. Mischley gives us a roadmap to what successful people do, linking topics that many of our previous world-leading speakers have spoken to us about before.Much of the session focuses on The Parkinson Symptom Tracker (PRO-PD App) designed as a tool for assessing and tracking symptom severity over time. It is freely available on the iOS and Android app stores. For more information: see https://pd-symptoms.com/ and watch this video by Dr. Mischley https://www.youtube.com/watch?v=5tx8rNBWx4MIf you are interested in participating in research (~ 3 hours per year answering online questions), please consider participating in the ongoing Modifiable Variables in Parkinsonism Study: https://mvp-study.com/About the speaker:-Dr. Laurie Mischley is a naturopathic physician and researcher specialising in the treatment and management of Parkinson's disease (PD). With over 20 years of experience in the field, she has become a leading expert in the use of natural therapies for PD. Dr. Mischley studied naturopathic medicine (ND) at Bastyr University and epidemiology (MPH) and nutritional sciences (PhD) at the University of Washington. Her work is focused on identifying the nutritional requirements unique to individuals with PD. She has published on coenzyme Q10, lithium, glutathione and mitochondrial deficiency in PD. She is Principal Investigator of the Modifiable Variables in Parkinsonism Study (mvp-study.com), which is attempting to describe why some people with PD progress slower than others. Dr. Mischley is working on ways to study, package and deliver evidence-based lifestyle modification as a therapeutic strategy. She founded the canine scent-based PD screening tool, ParK-9, developed a patient-reported outcome measure to assess PD severity (PRO-PD) and is instructor of the online series Parkinson School: https://pd-school.teachable.com/Dr. Mischley maintains a small clinical practice at Seattle Integrative Medicine focused on nutrition and neurological health.You can follow us on social media:-Instagram:-https://www.instagram.com/nosilverbullet4pd/Twitter:- https://twitter.com/NSB4PDAND NOW ON TIKTOK https://www.tiktok.com/@nosilverbulle... @nosilverbullet4pd998  IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted_button_id=WMV6D8DD7CVYUIf you want to join our mailing list for future speaker sessions then please email us at [email protected]

We are all becoming very aware of the huge benefits of exercise with PD but where do you start and what do you need to do?Julie Jones is a very experienced physiotherapist with a specialist interest in Parkinson’s and so is perfectly qualified to guide PwP to get more active and feel the benefits of exercise. This is an excellent and natural follow-up to the presentation by Prof Bas Bloem, also available on this channel and highly recommended if you have not watched it.If you would like a copy of Julie's slides then please email us at [email protected] Julie is a clinical academic fellow, jointly funded by Parkinson’s UK and the Chief Scientist Office and is a senior lecturer at Robert Gordon University. She is also a member of the Strategy Advisory board of Parkinson’s UK in Scotland and chairs the Scotland wide Parkinson’s Active project. She is also a member of the Parkinson’s UK College of Experts grant review panel, and sits on the Research Participation Steering Group at Parkinson’s UK. Within the Parkinson’s Excellence Network, Julie is the co-lead of the Exercise hub, which runs education events to support exercise professionals nationally to improve and develop service provision for people with Parkinson’s.Julie’s current role spans research, clinical and academic. Julie is currently funded to explore the feasibility and acceptability of a multicomponent intervention designed to support physical activity participation among people with Parkinson’s. Julie has an honorary physiotherapy position within NHS Grampian, and her main clinical interests include exercise and gait dysfunction.Julie can be contacted:-The Robert Gordon University  email [email protected] was the keynote speaker in 2022 at The Edinburgh Parkinson's Lecture   • Edinburgh Parkins...  IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...If you want to join our mailing list for future speaker sessions then please email us at [email protected]

We are delighted to bring you Dr. Rick Helmich on the topic of "Managing stress with Parkinson's"Dr. Rick Helmich was recommended to us by Prof Bas Bloem, who considers Rick to be the leading authority in this field. Rick will be discussing stress (both acute and chronic) and the effect that this has on people with Parkinson's disease.Rick's passion is to understand the cerebral mechanisms that lead to neurological diseases and use these insights to develop new therapies for patients with movement disorders. Rick works as a neurologist and associate professor specialising in Parkinson’s disease and tremor disorders at the Radboud University Medical Centre (with Prof Bas Bloem) and at the Donders Institute, both in the Netherlands. Rick is very much inspired by clinical observations in patients and uses neuroimaging and neurophysiology to understand the underlying mechanisms. He is particularly intrigued by the profound effects of psychological stress on many neurological movement disorders, by the way patients can compensate for brain dysfunction, and by the different ways in which tremor can manifest itself.Rick discusses:-1) What is stress?2) Can stress cause Parkinson's?3) How does stress influence Parkinson's?4)What can we do about it?You can follow us on social media:-Instagram:- https://www.instagram.com/nosilverbul...Twitter:- https://twitter.com/NSB4PDAND NOW ON TIKTOK https://www.tiktok.com/@nosilverbulle...IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...If you want to join our mailing list for future speaker sessions then please email us at [email protected]

Dear Friend, We are thrilled to announce the launch of a new YOPN Podcast, featuring an inspiring story about two of our very own co-founders of NoSilverBullet4PD, Michel Planquart and Mark Limebear. Through this podcast, you can discover how their friendship and shared experience of living with Parkinson's disease led them to create a community of support and understanding for those living with the condition. Whether you are living with Parkinson's disease, or know someone who is, this podcast is for you. Listen in and learn how their story of resilience and hope has made a profound impact on so many lives. It's a powerful reminder of the strength that comes when people come together and support each other. YOPN is Young-onset Parkinson's Network https://www.yopnetwork.org/Please share, thank you

Listen to this excellent presentation with a very good Q&A at the end, of Dr. Matthew Phillips exploring the potential therapeutic benefits of metabolic strategies, particularly fasting and ketogenic diets, in neurological disorders.Matt is a clinical and research neurologist at Waikato Hospital, Hamilton, New Zealand. His foremost passion is to explore the potential feasibility, safety, and efficacy of metabolic strategies, particularly fasting and ketogenic diets, in creating alternate metabolic states that may benefit people with a variety of neurological disorders. His team conducted the world’s first randomized studies involving only people with Parkinson’s, followed by Alzheimer’s. Further resources:-Metabolic Strategies in Healthcare paperhttps://www.ncbi.nlm.nih.gov/pmc/arti...Parkinson's RCThttps://movementdisorders.onlinelibra...Metabolic Plan (click Resources)https://www.metabolicneurologist.com/IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. Thank you & just follow this link:-https://www.paypal.com/donate/?hosted...To join our mailing list for future speaker sessions please email us at [email protected]

Dr. Simon Stott talks to us about his main PD research takeaways from 2022 and the research results he will be looking for in 2023.Simon is the Director of Research at Cure Parkinson's. The trust is an international supporter of both lab- and clinic-based research on Parkinson's.Originally from New Zealand, Simon has more than 20 years of experience in the field of Parkinson's research - in both the academic and biotech sectors. He has been involved in lab-based research as well as clinical studies.He also maintains the ‘Science of Parkinson’s’ website, which attempts to explain in plain English the research currently being conducted on Parkinson’s.https://scienceofparkinsons.com/about/Twitter:- https://twitter.com/ScienceofPDCure Parkinson's Trust:-https://cureparkinsons.org.uk/ambroxo...Twitter:- https://twitter.com/CureParkinsonsTPD Frontline:-  https://pdfrontline.com/en/ambroxolIF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...

Dr. Alfonso Fasano is one of the World's leading authorities on Parkinson's disease and joined us to talk about some of his specialties, DBS, Focused Ultrasound, and Infusion Pumps.Dr. Alfonso Fasano holds the Chair in Neuromodulation at the University of Toronto andUniversity Health Network.He is a Professor in the Department of Medicine (Division of Neurology) at the University of Toronto.He is staff neurologist and co-director of the SurgicalProgram for Movement Disorders at Toronto Western Hospital, University Health Network.He is also staff neurologist at the Hospital of Sick Children in Toronto.Dr. Fasano is a Clinician Investigator at the Krembil Research Institute and KITE – Toronto Rehabilitation Hospital.Dr.Fasano leads the Core E (closed-loop capabilities) of the Center for Advancing Neuro Technological Innovation to Application (CRANIA) and sits in the scientific advisory board of the Dystonia Medical Research Foundation and International Essential Tremor Foundation.He’s the chair of the Normal Pressure Hydrocephalus study group and of the Tremor study group of the International Parkinson Movement Disorders Society and the co-chair of the Functional Neurosurgical Working Group of the Parkinson Study Group; he’s also member of the Tremor Research Group.Dr. Fasano received his medical degree from the Catholic University of Rome, Italy, in 2002 and became a neurologist in 2007. After a 2-year fellowship at the University of Kiel, Germany, he completed a PhD in neuroscience at the Catholic University of Rome.His main areas of interest are the treatment of movement disorders with advanced technology (infusion pumps and neuromodulation), pathophysiology, and treatment of tremor and gait disorders. He authored more than 450 scientific papers and book chapters.Dr. Fasano is the co-editor of the section “Gaps and Controversies” of Movement Disorders Journal and editorial board member of Annals of Neurology, Movement Disorders Journal, Movement Disorders Clinical Practice and Parkinsonism and Related Disorders. He is also the principal investigator of several clinical trials.You can find out more about Dr. Fasano here:-https://www.michaeljfox.org/researche...https://www.uhnresearch.ca/researcher...https://vjneurology.com/speaker/alfon...https://www.youtube.com/watch?v=2MHGy...Follow Dr. Fasano onTwitter

Red Light Therapy (Photobiomodulation) & the science behind its possibilities is a growing topic within the Parkinson's community. Listen to this Podcast, the second of two, that No Silver Bullet recorded in Oct 2022 with Dr. Catherine Hamilton.We were delighted to host Dr.Catherine Hamilton, a retired medical practitioner & author of the Red Lights on the Brain blog.  The topic of Catherine's 2nd talk was to update us on developments regarding Red and near-infrared lights and how they help degenerative neurological diseases.The potential health value of red light was recognised over a century ago. It took another 90 years for medical researchers to rediscover the potential, and restart research into the health effects of red and near-infrared light on conditions such as Parkinson’s disease.More information can be found on Catherine's website https://www.wellred.com.au/If you want to build your own device then Catherine has very kindly created a comprehensive guide that you can find on her blog site herehttps://redlightsonthebrain.blog/IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...NB: Please note that we have no commercial relationship with our speakers. We simply organise topics that our members have shown an interest in and are welcome to receive other suggestionsTo get alerts for future speaker sessions email us at [email protected] Twitter:- https://twitter.com/NSB4PDInstagram:- https://www.instagram.com/nosilverbul...

Professor Bloem is one of, if not the World's leading authorities on Parkinson's disease. He shares with us his research on this important topic and helps us understand how to best manage our symptoms through exercise.The expression “citius, fortius, altius” (Latin for “faster, higher, stronger”) is the Olympic motto indicating what is required to achieve athletic excellence. Which of these skills is most important to reach an optimal personal performance was not specified by its creator, Pierre de Coubertin, but a combination is presumably optimal.Similar issues are at play when trying to understand the beneficial outcomes of physical activity on general health and motor functioning in people with neurological disorders such as Parkinson's Disease.---------------------Professor Bas Bloem is consultant neurologist at the Department of Neurology, Radboud University Medical Centre, The Netherlands. He is without a doubt one of the world’s top Parkinson’s specialists and has just received the prestigious Dutch "Stevinpremie" award.Professor Bloem has published over 850 publications and has held too many positions and received too many awards to mention.In 2002, he founded and became director of the Radboud UMC Centre of Expertise for Parkinson & Movement Disorders, which is recognised as a centre of excellence for PD.He also developed ParkinsonNet, an innovative healthcare concept that consists of 70 professional networks for PD patients, covering all of The Netherlands. This initiative has received several awards.IF YOU CAN, PLEASE DONATE TO NO SILVER BULLET 4PD. We are self-funded, so pay for our costs ourselves, which include licenses for our secure Webinar platform, our Podcast hosting platform and soon-to-be-launched paid advertising on Facebook and Instagram so that we can target and share these sessions with more PwP worldwide, in the hope that some of our speaker's content, may improve the symptoms of another PwPThank you & just follow this link:-https://www.paypal.com/donate/?hosted...Want alerts for future speaker sessions? Email us at [email protected] can follow us on social mediaInstagram:-  @nosilverbullet4pd https://www.instagram.com/nosilverbul...Twitter:- @NSB4PD  https://twitter.com/NSB4PD

Simon is the Deputy Director of Research at Cure Parkinson’s reviewing in January 2022, stand-out research that took place in 2021.Simon also gives us his top research tips to look out for in 2022 with the repurposing of drugs.The Cure Parkinson's Trust is an international supporter of both lab- and clinic-based research on Parkinson’s. Originally from New Zealand, Simon has 20 years of experience in the field of Parkinson’s research - in both the academic and biotech sectors. He has been involved in lab-based research as well as clinical studies. He also maintains the ‘Science of Parkinson’s’ website, which attempts to explain in plain English the research currently being conducted on Parkinson’s.The Science of Parkinson's, by Dr. Simon Stott:https://scienceofparkinsons.com/about/Twitter:- https://twitter.com/ScienceofPDCure Parkinson's Trust:-https://cureparkinsons.org.uk/people/...Twitter:- https://twitter.com/CureParkinsonsTInstagram:- https://www.instagram.com/cureparkins...Facebook:- https://www.facebook.com/cureparkinsons/If you want to join our mailing list for future speaker sessions or would like the Powerpoint notes of this session then please email us at [email protected]

This presentation gives an overview in April 2022 of research and clinical development for Parkinson’s, starting with an overview of trends. The 350+ active projects will be categorised by their position on the road to the patient and the objective, whether it is for symptom relief or disease modification. If you would like a link to the presentation slides, just email us at [email protected] a Ph.D. biochemist, Dr. Kevin McFarthing’s career included R&D leadership positions in life sciences research products with Amersham, diagnostics with Serono, and consumer healthcare with Reckitt Benckiser. He is joint editor of the Clinical Trial Highlights section of the Journal of Parkinson’s Disease and a member of the Research Committee of Cure Parkinson’s and is first author on a recent review of the clinical trial pipeline in Parkinson’s (https://content.iospress.com/articles... ). Kevin collates the Parkinson’s Hope List,  a database of potential therapies in research and clinical stages. Here is the link:-https://drive.google.com/file/d/1NeSy...He also chairs the Patient and Public Involvement and Engagement group for the Edmond J Safra Accelerating Clinical Trials in Parkinson’s Disease program. Kevin was diagnosed with Parkinson’s in 2012 at the age of 55.You can follow Kevin's social media on:-Twitter @InnovationFixer

We were delighted to host Lucy Jung CEO and Alex Dallman-Porter COO of Charco Neurotech, discussing their highly anticipated device the CUE1.CUE1 is a small non-invasive device that is worn on the body to administer specialised vibratory stimulation to relieve the movement symptoms of Parkinson’sIt combines the principles of Focussed Vibrotactile Stimulation and Cueing, which have been shown throughout scientific literature to improve motor performance and help with freezing respectively.Their Beta user testers have reported a wide range of benefits including:Smoother walking and movementRegaining the ability to danceHelping fine motor tasksDuring initial user trials, they found that their user’s movement improved by an average of 16%, with every participant feeling some improvement, additive to that of their medication.They have also had reports that the stimulation has a relaxing or reassuring effect, and some have requested to use the device to help with stressful situations like public speaking.To learn more about "How it works" click here https://charconeurotech.com/how-it-wo...Or watch Charco's YouTube Video https://youtu.be/7cQ7XMQ2LWIThe CUE1 is available in the UK / Europe and other countries as regulatory approval is gained.To add your name to the waiting list use this link:- https://charconeurotech.com/waiting-l...If you have any questions then feel free to message Lucy, Alex, and their team using https://charconeurotech.com/waiting-l...You can follow their progress...On Facebook https://www.facebook.com/CharcoLtd/Twitter @CharcoltdInstagram @Charcoltd

Diagnosed with Parkinson’s Disease when he was 7 yrs old, Matt has lived with the disease for forty-six years and has become an expert in his own condition.  His positive attitude is both amazing and very infectious so do take time to watch.This is a rare opportunity to learn from someone who has so much experience with Parkinson’s disease.Matt spends much of his time as an advocate for all things PD.  He has created these videoshttps://www.youtube.com/watch?app=des...https://www.facebook.com/watch/?v=533...https://www.mirror.co.uk/news/uk-news...He works with the Havas Lynx group https://www.youtube.com/c/HAVASLYNX/f...He has a website that raises awareness for PD with a smile and humor so look up https://www.parkylife.com/Follow him on social mediaTwitter https://twitter.com/MattEagles and https://twitter.com/PKYLIFEInstagram https://www.instagram.com/matteagles_... and https://www.instagram.com/parkylife_o...

We were delighted to welcome Joy Milne who shared her incredible story of how she discovered that she could smell Parkinson's Disease on people. Her story is so much more than that so please watch as she shares her journey with us and tells us how she is helping to enable the early detection of this disease.Thank you Joy.Follow Joy on social media Twitter https://twitter.com/stumpw0rk50?lang=enLinks:-https://scienceofparkinsons.com/tag/joy-milne/https://www.youtube.com/watch?v=pbNpfOZZkBk&t=15shttps://www.youtube.com/watch?v=XB0QgwVffvk&t=0shttps://www.manchester.ac.uk/research/beacons/breakthroughs/parkinsons-early-diagnosis/

We were delighted to host Dr.Catherine Hamilton, a retired medical practitioner and author of the Red Lights on the Brain blog.  Together with Ron Brown, an electronics engineer, Catherine established Well Red Pty a company that produces and distributes the "Well Red Coronet".The topic of Catherine's talk was, "Red and near-infrared lights – can they help degenerative neurological diseases?"The potential health value of red light was recognised over a century ago. It took another 90 years for medical researchers to rediscover the potential, and restart research into the health effects of red and near-infrared light on conditions such as Parkinson’s disease.More information can be found on Catherine's website https://www.wellred.com.au/Linkshttps://www.science.org/content/artic...https://parkinsonsdisease.net/news/li...https://www.semanticscholar.org/paper...https://scienceofparkinsons.com/2019/...NB: Please note that we have no commercial relationship with our speakers. We simply organise topics that our members have shown an interest in and are welcome to receive other suggestionsWant alerts for future speaker sessions? Email us at [email protected] us on social mediaInstagram:- @nosilverbullet4pdTwitter:- @NSB4PD

An excellent discussion in which Professor Roger Barker shares his expertise on whether it is possible to repair the brain in Parkinson's disease using cell-based therapies?Questions include:-What is Parkinson's disease?What are we trying to repair in PD?What is the target population for cellular therapy?How close have we come with Dopamine cell transplants on patients so far?Professor Roger Barker is a Professor of Clinical Neuroscience at the University of Cambridge and a Consultant Neurologist at the Addenbrooke’s Hospital Cambridge. He is a primary investigator in the Wellcome – MRC Cambridge Stem Cell Institute and the Director of the MRC funded UKRMP Stem and Engineered cell hub. His research seeks to better define the clinical heterogeneity of two common neurodegenerative disorders, namely Parkinson’s and Huntington’s disease, and their treatment, especially with experimental cell and gene-based approaches.More information can be found with these links:-G-Force PD research http://www.gforce-pd.com/Transeuro Trial https://transeuro.org.uk/Professor Roger Barker https://www.neuroscience.cam.ac.uk/di...Lund University https://www.lunduniversity.lu.se/luca...Want alerts for future speaker sessions? Email us at [email protected] can follow us on social mediaInstagram:- https://www.instagram.com/nosilverbul...Twitter:- https://twitter.com/NSB4PD

Motivated by a friend’s suffering from Parkinson’s, Dr. Sackner-Bernstein focused on a gap in our understanding of the disease: no one had so far measured the amount of dopamine in the dopaminergic neurons of people with Parkinson’s. This is critically important because he believes dopamine is toxic to these cells, which would then be a driver of neuron dysfunction and death, leading to disease progression.He published his analysis last summer in the Journal of Parkinson’s disease showing that these critical neurons do not lack dopamine – they have excess dopamine. This led him to design a clinical trial to test a drug that addresses this newly defined mechanism of disease.About Jonathan:-Dr. Jonathan Sackner-Bernstein was a renowned clinical trialist in cardiology before leaving academics to pursue medical product development, including drug, device, and biologic therapeutics.He served as associate director of the FDA’s device center, where he led diverse programs highlighted by the White House’s first Entrepreneurs-in-Residence program, the Center’s innovation initiative that led to the Breakthrough Devices program and a collaboration between FDA and DARPA to develop systems and products for the Medical Countermeasures Program (focused on responses to chemical, biologic and radiologic mass casualty events).After serving at the FDA, Jonathan consulted for DARPA, with responsibilities including regulatory strategy and commercial transition of their programs/projects. Jonathan supported the launch of DARPA’s Biological Technologies Office, with a primary focus on neuroscience and big data programs.Jonathan’s academic experience ranges from First-in-Human to international trials, as a clinical investigator and trial leader. Sackner-Bernstein held academic appointments in cardiology at Columbia University and North Shore LIJ Health System (Northwell) following training at Mount Sinai Medical Center. He earned his undergraduate degree in electrical engineering at the University of Pennsylvania.More information can be found with these links:-https://www.prnewswire.com/news-relea...https://en.wikipedia.org/wiki/Jonatha...https://www.youtube.com/watch?v=0tSCd...Email us at [email protected] for updates on future sessionsFollow us on social mediaInstagram:- @nosilverbullet4pdTwitter:- @NSB4PD