PODCAST · health
PEPtalk
by Jake & Cynthia
A twice-weekly, AI-hosted podcast on the peptide market. Mondays: deep dives — a fast pulse on the big GLP-1 names plus one molecule unpacked in full. Fridays: the week in review — the biggest stories from the lab, the market, and the regulators, all in about fifteen minutes. Hosted by Jake and Cynthia. For research and informational purposes only — not medical advice.
Episodes
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6: Peptalk Week in Review — October 16, 2026
This week the biggest story isn't a trial readout — it's the economy reshaping itself around GLP-1s. Jake and Cynthia unpack Gallup's new numbers (15% of US adults have tried a GLP-1 for weight loss, up from 3% two years ago), the Cornell grocery-receipts study (household spending down 5.3%…
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5: Peptalk Deep Dive — Tesamorelin
Last week: Sermorelin, the elegant idea. This week: Tesamorelin - its bigger sibling, and the evidence heavyweight of the growth hormone peptide world. Jake and Cynthia unpack Tesamorelin — the full forty-four amino acid growth hormone releasing factor with a protective chemical cap, two Phase...
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4: Peptalk Week in Review — October 9, 2026
This week: both Lilly and Novo converged on $499/month cash pricing — and we walk the whole price ladder from list price to TrumpRx to the gray market. Plus: Petrelintide's Phase 2 amylin data (up to 10.7% at 42 weeks with placebo-like tolerability) and its diabetes sister trial, retatrutide's...
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3: Peptalk Deep Dive — Sermorelin
Sermorelin is having a moment. Jake and Cynthia unpack the growth hormone peptide everyone's pivoting to: what it is (a copy of your body's own GHRH signal), how it works (pulsatile, feedback-intact), what the research actually shows (nocturnal GH up, lean mass up in men, skin thickness up in…
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2: Peptalk Week in Review — October 2, 2026
EASD 2026 in Milan turned into a Lilly showcase — and Jake and Cynthia round up the whole week. Stories this week: (1) Retatrutide's full Phase 3 TRIUMPH-1 data — up to 25% weight loss at 80 weeks, plus knee osteoarthritis and sleep apnea improvements — and TRIUMPH-2 in type 2 diabetes published…
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Peptalk Pilot: Deep Dive — NAD+
Welcome to Peptalk! In our pilot episode, Jake and Cynthia go deep on NAD+ (nicotinamide adenine dinucleotide) — one of the most talked-about molecules in the peptide world right now, even though it's not technically a peptide at all. We open with a fast GLP-1 pulse: retatrutide's showstopping…
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ABOUT THIS SHOW
A twice-weekly, AI-hosted podcast on the peptide market. Mondays: deep dives — a fast pulse on the big GLP-1 names plus one molecule unpacked in full. Fridays: the week in review — the biggest stories from the lab, the market, and the regulators, all in about fifteen minutes. Hosted by Jake and Cynthia. For research and informational purposes only — not medical advice.
HOSTED BY
Jake & Cynthia
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Frequently Asked Questions
How many episodes does PEPtalk have?
PEPtalk currently has 6 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is PEPtalk about?
A twice-weekly, AI-hosted podcast on the peptide market. Mondays: deep dives — a fast pulse on the big GLP-1 names plus one molecule unpacked in full. Fridays: the week in review — the biggest stories from the lab, the market, and the regulators, all in about fifteen minutes. Hosted by Jake and...
How often does PEPtalk release new episodes?
PEPtalk has 6 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to PEPtalk?
You can listen to PEPtalk on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts PEPtalk?
PEPtalk is created and hosted by Jake & Cynthia.
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