PODCAST · science
QuidelOrtho Science BYTES Podcast
by QuidelOrtho
A monthly podcast for lab professionals covering current advancements in science and technology that can impact better patient care.
Episodes
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Episode 61: The cost of uncertainty: Infection, antibiotics and the race to prevent sepsis
The latest episode of QuidelOrtho Science Bytes covers one of the most daunting challenges in the ER today: Quickly identifying and treating sepsis patients. Host Josh Casey sits down with QuidelOrtho's Medical Science Liaison Chris Sanchez, MSN, RN, to hear about emerging approaches to quicker...
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Episode 60: Speed, stewardship and cardiac care: ADLM 2026 highlights
The latest episode of QuidelOrtho Science Bytes takes listeners inside the 2026 ADLM Annual Conference, where experts discussed emerging technologies and diagnostic innovations shaping the future of healthcare. Host Stephanie Kleewein speaks with three industry experts about advances in…
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From 2025 to 2026: How the drug landscape is changing
The latest episode of QuidelOrtho Science Bytes explores how the overdose crisis has evolved from 2025 to 2026 and what these changes mean for laboratories and healthcare providers. Host Josh Casey is joined by Vonda McAllister, Director of Global Product Management at QuidelOrtho, to discuss...
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What we wish we knew: Understanding HDFN
Our latest episode of QuidelOrtho Science Bytes explores hemolytic disease of the fetus and newborn (HDFN) – a complex and often misunderstood condition that can have life-threatening consequences during pregnancy. Host Michelle Mullens is joined by Bethany Weathersby, Founder of the Allo Hope...
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Understanding and addressing syphilis trends in the United States
Our latest episode of QuidelOrtho Science Bytes addresses a public health paradox: while early-stage syphilis cases in the U.S. are declining, congenital syphilis continues to rise despite being entirely preventable. Host Josh Casey is joined by Andrea Ott‑Vasconi, Director of Scientific Affairs...
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Every minute matters: The power of high-sensitivity troponin
Our latest episode of QuidelOrtho Science Bytes features Dr. Lindy Carlstrom, Global Medical Affairs Manager for Acute Care, unpacking how high-sensitivity troponin is reshaping early cardiac diagnosis, where seconds matter most. From detecting heart injury earlier and reducing emergency…
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Blood Donor Awareness
Our 55th episode of QuidelOrtho Science Bytes features Michelle Mullens, Global Portfolio Marketing Manager for Transfusion Medicine, diving into the evolving realities of today’s blood supply, and why steady, year‑round donation is critical to modern healthcare. From the constant demand driven…
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2025 Diagnostic Trends and Innovations
Our 54th episode of QuidelOrtho Science Bytes features Jonathan Siegrist, PhD, Executive Vice President of Research & Development and Chief Technology Officer, exploring the breakthroughs shaping diagnostics in 2025. From high-sensitivity troponin testing for faster cardiac care to non-invasive...
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Don’t Wait for the Wake-Up Call
Our 53rd episode of QuidelOrtho Science Bytes features Dr. Qian Ding, MD, PhD, exploring why early detection of diabetes is a clinical and economic imperative. From identifying silent disease progression to leveraging smarter lab platforms, early testing empowers clinicians to intervene sooner,...
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The Power of informatics in Clinical Decision-Making
Our 52nd episode of QuidelOrtho Science Bytes features George Wierschem, Senior Global Product Manager – informatics, discussing how informatics is transforming clinical labs. From streamlining workflows to strengthening cybersecurity, informatics helps labs turn data into decisions – faster,...
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Through the Shades of Illness, Testing Brings Clarity
This episode features Dr. Terry O’Neil, President and Medical Director of Urgent Care Pros, discussing why testing is essential when symptoms overlap during respiratory season. With conditions like strep, flu, RSV and COVID-19 often appearing similar at the outset, timely diagnostics provide...
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Staying Vigilant Against Respiratory Illnesses This School Year
Our 50th episode of QuidelOrtho Science Bytes features Dr. Jonathan Temte, a leading public health expert, discussing how schools, families, and healthcare providers can stay ahead of respiratory illnesses this school year. As students return to classrooms, familiar viruses like flu, RSV, and...
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How Urgent Diagnostic Testing Can Help Prevent Drug Overdose Deaths
In this episode, you'll hear a conversation with our own Vonda McAllister about the critical role of rapid diagnostic testing in helping prevent drug overdose deaths. Discover how early detection in emergency departments enables timely interventions when patients present with altered mental…
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Bloodlines: The Connection Between Blood Donation and Patient Health
In this episode, you'll hear a conversation with transfusion medicine expert Michelle Mullens about how blood donation underpins patient health and the critical role it plays in healthcare. Discover how donated blood is vital not only for trauma care, but also for cancer treatments, chronic...
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Diagnostic Pathways to Women’s Health and Wellness
In this episode, you'll hear a conversation with three women's health experts about how early diagnostic testing is transforming care for heart disease, STIs, and preeclampsia. Discover how proactive screening empowers women, supports personalized care, and helps shift healthcare from reaction to...
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Beyond burnout: Key factors and strategies to solve the laboratory staffing crisis
In this episode, we spotlight the essential yet often-overlooked role of medical laboratory technologists – the backbone of today’s healthcare. With 70% of clinical decisions relying on lab results, these professionals face challenges including staffing shortages, rising diagnostic demands…
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Under attack: Sepsis and patient safety in the age of antibiotic resistance
This episode discusses the growing threat of sepsis, a life-threatening condition caused by the body's overwhelming response to an infection. It explores the connection between the rise in sepsis cases and the increasing problem of antibiotic resistance, highlighting the importance of effective...
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Take heart: How Point-of-Care Cardiac Diagnostics Save Time and Lives
In this episode, we’ll discuss the importance of cardiac testing at the point of care with two renowned experts on the topic, doctors Martin Than and Paul Collinson. Both of our guests today have extensive experience on the front lines of patient care and have witnessed firsthand how…
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Value of Metrics in the Laboratory Environment
In this episode, we’ll explore how quality performance metrics are transforming clinical laboratory operations and why measuring the details – from accuracy to turnaround times – are essential for improving everything from test results to patient care. About Our Speaker: Johanna Miller, Global...
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Preventing Rh Disease, the evolution from discovery to ongoing challenges
Rh disease remains a significant health challenge, particularly impacting expectant mothers and their newborns. In this episode of Science Bytes, Dr. Steven Spitalnik discusses the milestones in Rh disease treatment, the ongoing challenges and future opportunities to combat this condition. About...
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Spotlight on syphilis: Breaking the chain with early detection
The syphilis epidemic in the U.S. is a growing public health crisis, with rates increasing by 76% from 2018 to 2022. Syphilis is preventable and curable, but early detection is key—especially for pregnant women, where timely testing can prevent congenital syphilis. Don’t miss this episode on the...
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She's not 'just tired': Exposing the hidden thyroid epidemic in women
Did you know that women are 10 times more likely than men to develop a thyroid condition, yet often remain undiagnosed due to medical bias and lack of awareness? We often see women present themselves to an emergency department with health concerns that are brushed off as “stress” or...
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Identifying Lesion-Causing Viral Pathogens
The World Health Organization estimates 3.7 billion people under age 50 (67%) globally have herpes simplex virus type 1 (HSV-1) infection, the main cause of oral herpes, and 491 million people aged 15–49 (13%) worldwide have a herpes simplex virus type 2 (HSV-2) infection, the main cause of…
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Hyperhemolysis Syndrome in the Patient With Sickle Cell Disease
Sickle cell disease (SCD) patients are at risk of developing multiple complications from transfusions, including alloimmunization to red blood cell antigens, delayed hemolytic transfusion reactions and hyperhemolysis syndrome (HHS). While HHS is a rare complication of repeat blood transfusions in...
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Sigma Metrics and the Value of Real World Evidence
Six Sigma is a popular way to measure quality. Sigma metrics have been adapted for the clinical laboratory by incorporating observed accuracy, precision and total error allowed (TEa). In vitro diagnostic (IVD) manufacturers have used Six Sigma to assess the quality of their assays using a small...
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A Comprehensive Discussion of Reference Intervals
Reference intervals (RIs) are a fundamental decision support tool used by clinicians and lab professionals to interpret laboratory reports and assess an individual’s health status. The establishment of reference intervals, however, can be challenging due to many physiological factors that…
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The Surprising Benefits of Becoming a Repeat Blood Donor
Each year 4.5 million lives are saved by blood transfusions thanks to blood donations. More than 118 million units of blood are donated worldwide every year but less than 10% of people who can donate blood will give. These repeat blood donors enjoy benefits of their own while providing their...
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Managing Febrile Transfusion Reactions
Transfusion reactions are adverse events associated with the transfusion of whole blood or one of its components. They range in severity from minor to life-threatening and can occur during a transfusion, termed acute transfusion reactions, or days to weeks later, termed delayed transfusion...
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Partial D Phenotype and Hemolytic Disease in Babies
Alloimmune hemolytic disease of the fetus and newborn (HDFN) may occur when a pregnant woman has an antibody against an antigen on the fetal red cells inherited from the father. Many antibodies to red blood cell antigens can cause HDFN, including those from the ABO, Rh, and other blood group...
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The Role of IVD To Detect Thyroid Disorders and Ensure Proper Treatment
According to the American Thyroid Association, as many as 60 percent of those with a thyroid disorder are unaware of their condition, and women are 5 to 8 times more likely than men to develop thyroid disease. If left untreated, thyroid dysfunction increases an individual’s risk for other serious...
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How Are Blood Groups Discovered?
The fascinating history of the discovery of blood groups goes back to 1900 with the breakthrough that came when Dr. Karl Landsteiner, an Austrian scientist, discovered three human blood groups. These were the A, B, and O blood groups. Two students who worked with Karl Landsteiner discovered the...
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The Evolving Cybersecurity Environment in Laboratories
The cybersecurity landscape continues to evolve. Health Care Companies Are the #1 Target for Cyberattacks and Data Breaches. The pace of the release of cybersecurity guidance and regulations for medical devices across the globe has been accelerating. Globally, some regulatory bodies have…
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Diagnostic Testing for Type I/II Diabetes and Associated Complications
World Diabetes Day takes place each year in the month of November, created to raise awareness about the disease. Diabetes is a global health threat diabetes with the number of people living with diabetes continuing to rise. Diagnostic testing is one of the major tools to help prevent and manage…
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Resolving Antibodies to High-Prevalence Antigens
High-prevalence antigens occur in greater than 99% of the population. Antibodies to high-prevalence antigens are rare and may be difficult to identify due to the lack of antigen-negative panel cells for these antigens. Examples of antibodies to high-prevalence antigens are: anti-k, anti-Kpb,...
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Understanding sepsis, its detection and treatment strategies
Sepsis occurs when the body’s immune system responds to an infection and injures its own tissues and organs. It is a medical emergency, requiring early detection and treatment as it can lead to septic shock, multi-organ failure, and death. One in five deaths worldwide is associated with sepsis…
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Key Learnings on Rare Blood Programs
A rare donor program is a collaborative effort of many blood centers and/or hospitals to combine their rare donor resources to supply what they have to patients in need. These centers work to identify rare donors by screening methods and inclusion in database systems. Learn in this episode what...
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The Need for Safe and Reliable Blood Donations for the Sickle Cell Disease Population
In Sickle Cell Disease (SCD) patients, one of the most critical treatments is a blood transfusion. A blood transfusion is used to provide normal red blood cells to the patient’s body. Red blood cell transfusions help lessen anemia and reduce the blood’s viscosity, allowing it to flow more freely,...
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The importance of extended antigen typing in Transfusion Medicine
Review the role of extended antigen typing or phenotyping in Transfusion Medicine. How this practice plays a significant role in the transfusion of sickle cell, thalassemia, and myelodysplastic syndrome patients as well as other chronically transfused patients, preventing the development of…
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The Role of the Lab in Diagnosing and Monitoring Hepatitis C Virus Infection
The World Health Organization estimated that during 2019, 58 million people worldwide were living with the Hepatitis C virus (HCV) which causes inflammation of the liver. All types of hepatitis can be controlled or prevented. There is a cure for Hepatitis C; however, HCV infection is often...
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Laboratory Investigations for Maternal Health Testing
Maternal health refers to the health of the women during pregnancy, childbirth, and the postnatal period. Each stage should be a positive experience, ensuring women and their babies reach their full potential for health and well-being. Prenatal care includes screening and diagnostic tests and…
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Diagnosing Chronic Kidney Disease
It is estimated that between 8 and 10% of the global adult population has some form of kidney damage. Early detection of kidney damage is critical. If left undetected, chronic kidney disease can lead to kidney failure which means regular dialysis treatment or a kidney transplant is necessary for...
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Heart Failure and the role of NT-proBNP
Heart Failure (HF) is a common disease that affects an estimated global population of over 40 million. It is the most frequent cause of hospitalizations in patients over the age of 65, placing a considerable financial and social burden on patients, healthcare providers, and care providers.…
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Role of the Donation Screening Lab
The need for a sufficient supply of safe blood is constant and globally there is an ongoing need for effective blood programs as they are critical to support patient management. The role of the donor/donation screening lab is fundamental to the protection and maintenance of the donor inventory…
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Ensure safety with a Quality Certificate Program
Donor and product safety has improved significantly over the last decade as a consequence of the introduction of measures such as evidence-based blood donor selection criteria. In parallel, the implementation of quality assurance programs based on good manufacturing practices has also played a…
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The Role of the Lab in the Prevention and Management of Diabetes: A Physician’s Perspective
Diabetes is a global health threat diabetes with the number of people living with diabetes continuing to rise. Diagnostic testing is one of the major tools to help prevent and manage the disease. In this podcast episode, we will have a conversation with Dr. Ivan Salgo, Head of Medical, Clinical,...
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Key learnings from COVID-19 for the Labs with Dr. Arturo Casadevall
The COVID-19 pandemic has been already in our lives since late 2019 and the variants surge is rapidly increasing. Is there anything we can learn from the experience? Fast forward to the fall of 2021, what are the recommendations for Hospitals and Laboratories around the world for the current...
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Automation is Possible for All Laboratories
Description: With increasing compliance requirements and resource challenges around the world, there is a growing need for the integration of digital platforms to reduce errors, reduce the need for double checks/signoffs, and provide greater process efficiency. There is a need for laboratories to...
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How to manage Partial D in donors and patients
After the success of our April episode, “Your Lab Journey With the Rh System and Weak D,” we continue the topic. Tune in for a conversation about partial D, the differences, types, and implications it has on transfusion. Sue Johnson serves as director of Versiti’s Specialist in Blood Banking…
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Are Process Excellence and Lean the same thing?
Process Excellence is a proven way to cut costs, raise productivity, and improve service levels. PEx® combines the tools and methodologies of: Six Sigma—measuring and reducing your error and defect rate Lean Thinking—eliminating waste to speed your workflow and deliver better value. Design...
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Overcoming the Challenges of Blood and Plasma Supply with Dr. Pampee Young
Every two seconds someone in the U.S. needs blood. It is essential for surgeries, cancer treatment, chronic illnesses, and traumatic injuries. Whether a patient receives whole blood, red cells, platelets, or plasma, this lifesaving care starts with one person making a generous donation. 1 blood...
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