PODCAST · health
RheumaCast
by Dr. Denis Poddubnyy
RheumaCast dives into the latest developments in rheumatology, offering in-depth discussions on research, clinical advances, and expert comments. Each episode sheds light on significant publications, upcoming events, and evolving trends in the field. Perfect for rheumatologists, healthcare professionals, and researchers eager to stay at the forefront of rheumatology.
Episodes
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Subclinical Psoriatic Arthritis: Does it Really Exist?
In this episode of RheumaCast, we discuss the evolving concept of subclinical psoriatic arthritis and the challenges associated with its definition and clinical relevance. The episode explores current frameworks describing the transition from psoriasis to psoriatic arthritis, highlighting the...
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What is the relevance of structural damage in psoriatic arthritis?
In this episode of RheumaCast, we discuss the functional consequences of structural joint damage in psoriatic arthritis based on data from a large, prospectively followed cohort. While inflammation is often considered the main driver of impaired physical function, this study provides a more…
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Do we need new therapies in spondyloarthritis?
This episode of RheumaCast explores why many individuals with axial spondyloarthritis (axSpA) fail to achieve remission, despite access to advanced therapies. The discussion centers on two key factors often overlooked in daily practice: diagnostic inaccuracy and the presence of non-inflammatory...
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Sex Differences in Treatment Response in Axial Spondyloarthritis
In this episode of RheumaCast, we explore new data from the international PROOF cohort on sex-specific differences in achieving disease control in axial spondyloarthritis (axSpA). The authors present compelling evidence that women with non-radiographic axSpA (nr-axSpA) are significantly less…
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The Imaging Crisis in Axial Spondyloarthritis: Between Early Diagnosis and Overdiagnosis
In this episode of RheumaCast, we dive into the ongoing debate around imaging in axial spondyloarthritis (axSpA). While MRI has revolutionized early detection of sacroiliitis, it has also created new diagnostic challenges. We discuss why bone marrow edema alone is not enough for a confident...
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Why Treatment Fails in Axial Spondyloarthritis — And What We Can Do About It
In this episode of RheumaCast, we discuss one of the most frustrating aspects of axial spondyloarthritis (axSpA): treatment failure. Despite the availability of multiple biologic and targeted therapies, over half of patients do not achieve remission. What causes this non-response? We explore two...
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Sacroiliac Joint Variants: When Normal Anatomy Mimics Disease
In this episode of RheumaCast, we explore how anatomical variations of the sacroiliac joints (SIJ) can complicate the diagnosis and management of axial spondyloarthritis (axSpA). We walk you through common SIJ variants—such as crescent-shaped ilium, accessory joints, and transitional…
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Statistical Pitfalls in Rheumatology Research: 15 Tips from an Expert
In this episode of RheumaCast, we delve into common statistical missteps in rheumatology research—and how to avoid them. Professor Stian Lydersen shares insights from reviewing over 700 manuscripts for Annals of the Rheumatic Diseases and RMD Open. From handling missing data to the proper use of...
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Understanding Nociplastic Pain: What It Is and How to Treat It
In this episode, we explore a compelling review that tracesthe evolution of our understanding of nociplastic pain—from fibrositis to fibromyalgia and beyond. 🧠 Key Takeaways from the Discussion: ✅ The shift from peripheral to central painmechanisms in fibromyalgia ✅ How nociplastic…
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How to Detect Enthesitis? A Multicenter Study Comparing Ultrasound and Physical Examination in Spondyloarthritis
In this episode we discuss a recent multicenter study involving over 400 patients with spondyloarthritis, which explored the detection of enthesitis.Researchers compared ultrasound findings with physical examinations to assess agreement between the two methods across various lower limb entheses…
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EULAR Recommendations: Targeted Therapy in Inflammatory Arthritis and Cancer History
A new episode focusses on the recently published 2024 EULAR points to consider on the initiation of targeted therapies in patients with inflammatory arthritis and a history of cancer. This importnat guideline provides practical advice for rheumatologists navigating the complexities of managing...
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What is the impact of sex on treatment response in axial spondyloarthritis?
This study explores the impact of axial spondyloarthritis (axSpA) subtype and sex on the discontinuation of first-line biologic DMARDs (bDMARDs). The key findings indicate that patients with non-radiographic axSpA (nr-axSpA) and female patients are more likely to discontinue bDMARD therapy and...
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ASAS Definition of Difficult-to-Manage Axial Spondyloarthritis
This episode deals with the development of a consensus-based expert definition for difficult-to-manage (D2M) axial spondyloarthritis (axSpA), including treatment-refractory (TR) disease. The Assessment of SpondyloArthritisInternational Society (ASAS) spearheaded this effort through a literature...
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Colchicine or no colchicine in gout patients starting with urate-lowering therapy?
This research investigates the impact of colchicine, a medication used to prevent gout flares, on cardiovascular events in patients initiating urate-lowering therapy. Using a large UK primary care database, the study compared patients prescribed colchicine prophylaxis with those who received no...
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Can you get good medical advice from ChatGPT and similar AI chatbots? An example with back pain.
This study assesses the accuracy and readability of four AI chatbots (ChatGPT 3.5, Bing, Bard, and ChatGPT 4.0) in answering common patient questions about low back pain (LBP). Researchers evaluated responses against established LBP guidelines, finding moderate accuracy overall, but with...
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Extra-Musculoskeletal Manifestations in JAKi-Treated PsA and axSpA Patients
This episode deals with the development of extra-musculoskeletal manifestations (EMMs) in patients with psoriatic arthritis or axial spondyloarthritis treated with a Janus-kinase-1-Inhibitor upadacitinib. The study analyzed data from five clinical trials, comparing upadacitinib to placebo and...
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MRI Inflammation Resolution and Axial Spondyloarthritis Outcomes
This study investigates the link between MRI-detected inflammation and clinical outcomes in axial spondyloarthritis (axSpA) patients treated with a TNF inhibitor etanercept. Using data from the ESTHER trial, the study found a strong association between the resolution of inflammation on MRI and...
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How to differentiate between various causes of osteoproliferation in the hands?
This research article investigates the relationship between osteo-proliferative lesions on finger phalanges, sex, age, and osteoarthritis. Using X-rays of 1153 patients, researchers examined the frequency and location of these lesions, finding that men showed more lesions than women, with age and...
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How to differentiate between osteitis condensans and spondyloarthritis?
This study compares osteitis condensans ilii (OCI) and axial spondyloarthritis (axSpA), focusing on their clinical, laboratory, and MRI characteristics. Researchers found that OCI predominantly affects women and lacks the inflammatory markers typical of axSpA. While both conditions can present…
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TNF Blockade Ineffective for Chronic Low Back Pain Associated with Modic Type 1 Changes on MRI
This episode focuses on a randomized, placebo-controlled trial that evaluated the efficacy of infliximab, a tumor necrosis factor (TNF) inhibitor, in alleviating chronic low back pain in patients with Modic type 1 changes (degenerative disc disease with bone marrow edema) identified on magnetic...
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What is chronic non-bacterial osteitis (CNO)?
This article presents expert consensus recommendations for diagnosing and treating chronic non-bacterial osteitis (CNO) in adults. A systematic review of existing literature and a multidisciplinary expert panel informed the creation of a standardized disease definition and proposed the term "CNO"...
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Low Back Pain and Suspicion of Axial Spondyloarthritis – Does the MRI Protocol Matter?
This episode of RheumaCast deals the long-anticipated global consensus on MRI protocols for the diagnosis and differential diagnosis of axial spondyloarthritis (axSpA). Experts from ASAS and SPARTAN, including radiologists and rheumatologists, have developed a comprehensive, standardized imaging...
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Diagnosis of Axial Spondyloarthritis - Enhancing Rheumatologist-Radiologist Communication
This episode of RheumaCast dives into the latest expert guidelines from the Assessment of Spondyloarthritis International Society (ASAS) for imaging referrals in patients with suspected or confirmed axial spondyloarthritis (axSpA). We explore how these recommendations, designed by an…
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ABOUT THIS SHOW
RheumaCast dives into the latest developments in rheumatology, offering in-depth discussions on research, clinical advances, and expert comments. Each episode sheds light on significant publications, upcoming events, and evolving trends in the field. Perfect for rheumatologists, healthcare professionals, and researchers eager to stay at the forefront of rheumatology.
HOSTED BY
Dr. Denis Poddubnyy
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Frequently Asked Questions
How many episodes does RheumaCast have?
RheumaCast currently has 23 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is RheumaCast about?
RheumaCast dives into the latest developments in rheumatology, offering in-depth discussions on research, clinical advances, and expert comments. Each episode sheds light on significant publications, upcoming events, and evolving trends in the field. Perfect for rheumatologists, healthcare...
How often does RheumaCast release new episodes?
RheumaCast has 23 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to RheumaCast?
You can listen to RheumaCast on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts RheumaCast?
RheumaCast is created and hosted by Dr. Denis Poddubnyy.
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