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PODCAST · health

Sean Hashmi, MD

by Sean Hashmi, MD

Understand your kidney numbers and metabolic health. I'm Dr. Sean Hashmi, a board-certified kidney and obesity medicine specialist. I explain the research behind your lab results, food choices and daily habits in plain English.I'm the founder of SELF Principle, a nonprofit built around Sleep, Exercise, Love and Food.Free weekly newsletter: https://selfprinciple.org/newsletter/Website: https://www.seanhashmimd.com/For education only, not personal medical advice.

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Episodes

  1. Dialysis Timing: What Actually Decides When You Start

    Three people can have the exact same kidney number, and completely different futures. One needs dialysis this year. One never will. Nephrologist Dr. Sean Hashmi breaks down the biggest myth in kidney care: that a single eGFR number decides when you need dialysis. There is no eGFR threshold that...

  2. This Sign Means Your Kidneys Are Already Damaged

    Your kidneys can lose more than half their function and never once make you feel sick. Nephrologist Dr. Sean Hashmi walks through the real warning signs of kidney disease, including the ones almost everyone misses because they blame them on something else. Fewer than one in 20 people with early...

  3. Do Proton Pump Inhibitors Cause Kidney Disease?

    Do heartburn pills like omeprazole really damage your kidneys? Nephrologist Dr. Sean Hashmi breaks down what the actual research found, how big the risk really is, and who carries it versus who barely does. Large observational studies do show a higher rate of chronic kidney disease in people who...

  4. Can Kidney Disease Be Reversed? Here's What Really Happens

    Can kidney disease be reversed? A five-year study in PLOS Medicine found that about one in five people with kidney disease saw their numbers return to the normal range. Nephrologist Dr. Sean Hashmi explains what that finding actually means, and why it is different from the "reverse it naturally"...

  5. Silent Kidney Stone: Should You Watch It or Treat It?

    Roughly one in twenty CT scans done for something unrelated turns up a silent kidney stone, and "just watch it" is the advice most people hear afterward. Dr. Sean Hashmi, a board-certified nephrologist, walks through what long-term data actually says happens to a silent stone left alone: the risk...

  6. Can Food Really Lower Your Creatinine? What Actually Protects Your Kidneys

    Can food really lower your creatinine? Right now your feed is full of morning drinks and five-food lists that promise it will. Here is the part they leave out: you can move your creatinine number tonight without helping your kidneys at all. In this episode, Dr. Sean Hashmi separates what moves…

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  7. The 2026 Cholesterol Guidelines: The 2 Numbers Most Panels Leave Off

    Your "normal" cholesterol may be missing two numbers. In March 2026, the American College of Cardiology, the American Heart Association, and ten other organizations rewrote the cholesterol guideline your doctor has used since 2018. In this episode, Dr. Sean Hashmi breaks down what changed and the...

  8. Should You Take Blood Pressure Pills At Night? 21,000 Patients Answer

    Should you take blood pressure pills at night or in the morning? For years the advice was to dose at night to protect your heart. Then 21,104 patients put that to the test. In this episode, Dr. Sean Hashmi walks through what the trials actually found and what protects your heart and your kidneys....

  9. The Real Problem With Seed Oils Isn't What You Think

    Are seed oils actually bad for you? Seed oils have been blamed for inflammation, weight gain, diabetes, and heart disease. The uncomfortable part is what happens when you test it: when researchers feed people more of the main fat in seed oils and measure inflammation in their blood, it mostly…

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  10. Fatty Liver Doesn't Need Bitter Tonics—It Needs This

    Fatty liver: the only thing that truly reverses it. A video with over 100,000 views says a bitter tonic will empty the fat out of your liver. It will not. In this episode, Dr. Sean Hashmi covers what genuinely reverses fatty liver and why the detox drinks sold everywhere do nothing. Fatty liver,...

  11. High Creatinine? Here's What Actually Works.

    Your creatinine is high, and here is what actually lowers it. Your social media feed is full of teas and morning drinks promising to flush it down. Most do nothing, and some can actually harm your kidneys. In this episode, Dr. Sean Hashmi explains what really moves creatinine, what moves your…

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  12. MUSCLE → BRAIN

    Creatine isn't just for muscle. A video with millions of views says it shrinks your fat cells by 30%. The evidence does not show that, and the real story runs past muscle into your brain and into your kidney lab results. In this episode, Dr. Sean Hashmi sorts the creatine claims with data behind...

  13. The Blood Pressure Number That Protects Your Kidneys

    Are your blood pressure pills hurting your kidneys? Your social media feed keeps saying so. For most people, the truth runs the other way: the right medications are the strongest kidney protection we have. In this episode, Dr. Sean Hashmi explains which blood pressure medications protect your...

  14. The Belly Fat That Destroys Your Kidneys

    You can be thin, eat clean, hit your steps, and still have the kind of belly fat that destroys your kidneys. A 2023 PLOS One cohort followed 11,050 adults for nearly 6 years. The highest visceral fat group had 7.5 times the risk of chronic kidney disease. The most surprising finding: the effect…

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  15. The 10-Second Test That Predicts How Long You'll Live

    The 10-second balance test that predicts how long you'll live. If you can't stand on one leg for 10 seconds, one 2022 study found your risk of dying over the next several years was about 1.84 times higher, an 84% jump. That number comes from a 2022 study in the British Journal of Sports Medicine…

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  16. BMI Lies

    You can be thin, eat clean, hit your steps, and still have the kind of belly fat that destroys your kidneys. A 2023 PLOS One cohort followed 11,050 adults for nearly 6 years. The highest visceral fat group had 7.5 times the risk of chronic kidney disease. The most surprising finding: the effect…

    more
  17. Creatinine vs Cystatin C: Why Your Kidney Lab May Be Lying

    Your creatinine test may be lying to you. The 2021 National Kidney Foundation guidance recommends cystatin C as a second kidney test. Four years later, most labs still default to creatinine alone. By the time creatinine clearly rises on a lab report, you may have already lost a third or more of...

  18. 70 lbs Lost in a Trial: What Retatrutide Means for Your Kidneys

    A new triple-agonist shot, retatrutide, just posted the biggest weight loss we have ever seen from a single injection in a phase 3 obesity trial: 28.3% of body weight at 80 weeks, roughly 70 pounds, and almost double what Ozempic delivered in its pivotal trial. I'm a nephrologist and obesity...

  19. 5 'HEALTHY' FOODS WRONG FOR YOUR KIDNEYS

    If you have kidney disease, the smoothie your cardiologist told you to drink could be the single biggest reason your numbers are getting worse. The same foods you ate for 30 years without a problem can become a problem the day your kidney function drops. Most of the wellness advice on the…

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  20. This Kidney Number Predicts How Long You Live

    People who live to 100 share one quiet pattern that nobody talks about. It is not their cholesterol. It is not their gym routine. It shows up as a single number on a routine blood test, and 9 out of 10 people with abnormal kidney function have no idea theirs is wrong. In this episode, Dr. Sean...

  21. 5 Over-the-Counter Pills That Are Quietly Damaging Your Kidneys

    You probably have at least three of these in your bathroom cabinet right now. They cost $10, they feel harmless, and in the wrong person, taken often enough, they can damage kidneys for years without a single warning sign. In this episode, Dr. Sean Hashmi walks through five classes of...

  22. What the FDA Just Approved Ozempic For Has Nothing to Do With Weight

    A trial of 3,533 people with type 2 diabetes and chronic kidney disease was stopped early in late 2023. Not because something went wrong. Because the drug worked so well that leaving anyone on placebo was no longer ethical. That drug was Ozempic. Eight months later, the FDA approved semaglutide…

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  23. Foamy Urine? Here's What It Actually Means

    Foamy urine has a 1 in 5 chance of meaning your kidneys are leaking protein. Here's what kind of foam matters and the $30 test that catches it years before standard blood work. If you've been Googling foamy urine at midnight, zooming in on toilet bowls and wondering if it means kidney failure…

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  24. The 8 Glasses of Water Rule Is a Myth. Here's the Real Answer

    How much water should you actually drink each day? As a board-certified nephrologist, the honest answer is: it depends on your body, your kidneys, your climate, and your activity. The "8 glasses a day" rule was never based on a single scientific study. In this episode, you'll learn why the…

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  25. 10 Foods That Protect Your Kidneys (Nephrologist Approved)

    Kidney-friendly foods can either slow chronic kidney disease or speed it up, and most people have never heard the one number that explains why. Your body absorbs over 90% of phosphorus additives from processed food, but only 20 to 40% from whole plant foods. That single gap is the starting point...

  26. 5 Silent Signs of Kidney Damage 90% of People Miss

    Chronic kidney disease affects more than 1 in 7 US adults, and about 9 in 10 don't even know they have it. Kidneys can lose up to 50% of function before a single number on a routine lab panel looks abnormal. In this episode, Dr. Sean Hashmi walks through the 5 silent signs of kidney damage your...

  27. The 6 Proteins Ranked From Worst to Safest for Kidney Health

    If you ate chicken this week, there is a real chance you accidentally ate a processed meat without ever knowing it. In this episode, I walk you through the landmark study that changed how I counsel my patients on protein, the one published in the Journal of the American Society of Nephrology that...

  28. Kidney-Safe Snacks: 7 Swaps That Won't Spike Your Labs

    Kidney-safe snacks for CKD patients who are afraid to eat between meals. Most people with chronic kidney disease stop snacking entirely out of fear of potassium and phosphorus, but skipping meals can cause blood sugar instability, muscle loss, and malnutrition that accelerate kidney damage faster...

  29. The Supplement That Fakes Kidney Failure on Your Labs

    Your doctor sees a number on a routine blood test and tells you to stop the creatine. You stop it. Nobody explains that the lab result was a false alarm. Creatine raises serum creatinine — the exact molecule physicians measure to estimate kidney function. But raising creatinine is not the same as...

  30. Dry Cleaning Toxin: The 3X Increased Risk Most People Don't Know About

    A common dry cleaning chemical called tetrachloroethylene, or PCE, has been linked to a threefold higher risk of significant liver fibrosis. 7% of Americans already have measurable levels of this chemical in their blood. And PCE doesn't stop at the liver. It also damages your kidneys directly by...

  31. Should You Quit Coffee? Who Needs to Stop (and Who Doesn't)

    Should you quit coffee? In this final episode of the Coffee Science Series, Dr. Sean Hashmi breaks down who should be careful with coffee and who can keep drinking it without worry. Your genes play a bigger role than you think. A liver enzyme called CYP1A2 determines whether you're a fast or slow...

  32. Is Decaf Coffee Actually Safe? What Science Says

    Coffee is one of the healthiest beverages on the planet. But what you add to it can quietly undo every benefit. In this episode, Dr. Sean Hashmi breaks down the real science behind decaf safety, explains why popular creamers contain hidden phosphate additives that accelerate kidney damage, and...

  33. 3 Medical Shifts in 2026: Kidney Protection, Metabolism & Longevity | Live AMA

    The old CKD playbook -- bland diet, blood pressure pill, hope for the best -- is dead. In this live AMA, Dr. Sean Hashmi breaks down three major shifts happening right now in kidney and metabolic medicine heading into 2026. The Kidney Shift: The FDA just approved Ozempic for kidney protection in...

  34. Melatonin and Heart Failure: What 130,000 People Revealed

    Is your nightly melatonin safe? A groundbreaking study of 130,000 people presented at the 2025 American Heart Association Scientific Sessions found that long-term melatonin use was associated with nearly double the risk of heart failure. But before you panic, there's critical context you need to...

  35. Coffee Drinkers Have 20% Less Depression -- Here's Why

    Coffee doesn't just wake you up. It literally changes how your brain works. In this episode, I break down the latest research on coffee and brain health. A meta-analysis of observational studies found that people who drank 2-4 cups of coffee daily had about a 20-25% lower risk of depression. And...

  36. Stubborn Belly Fat? Your Kidneys Might Be the Problem

    Stubborn belly fat won't budge despite diet and exercise? Your kidneys may be the hidden culprit. Your kidneys clear over 50% of circulating insulin. When visceral fat compresses them, insulin stays elevated and your body gets locked in fat storage mode. This episode breaks down the kidney-belly...

  37. Coffee and Blood Sugar: Can It Prevent Diabetes or Make It Worse?

    Nearly 600 million people worldwide have diabetes. Could your morning coffee actually help protect you? In this episode, I break down what decades of research reveal about coffee and metabolic health. A meta-analysis of over 1 million people found that each daily cup of coffee was linked to about...

  38. Coffee and Kidney Disease: What 2025 Research Actually Shows

    SPOTIFY TITLE Coffee and Kidney Disease: What 2025 Research Actually Shows (Same core keyword focus works for podcast search) What if everything you thought about coffee and kidney health was wrong? Four years ago, I covered this topic in a video that hit over 2 million views. Since then, several...

  39. Pig Kidney Transplants: The 2025 Breakthrough That Changed Everything

    In 2025, we crossed a historic threshold. Multiple humans survived more than six months with gene-edited pig kidneys functioning inside them, in both the United States and China. For the 100,000 Americans waiting for a kidney right now, this matters. In this episode, I break down: What actually...

  40. IgA Nephropathy: The 5-Step Action Plan to Protect Your Kidneys

    Every IgA Nephropathy patient asks the same question: What do I do right now to stop my kidneys from failing? In this episode, I break down the exact 5-step action plan I give every patient in my clinical practice — based on the latest KDIGO guidelines and clinical trials like DAPA-CKD, NefIgArd,...

  41. IgA Nephropathy Diet: What to Eat to Protect Your Kidneys

    The right diet can cut proteinuria by 30%—without any medication changes. Most IgA nephropathy patients don't know what to eat. In this episode, I share the exact eating plan I give every patient in my practice. Simple, sustainable, and kidney-friendly. This isn't a restrictive diet where you...

  42. IgA Nephropathy: New Treatments Beyond Steroids

    IgA nephropathy treatment has changed dramatically since 2021—steroids are no longer your only option. In this episode, I break down the complete treatment roadmap based on the 2021 KDIGO guidelines and the latest clinical trials. This is the same tiered approach I use with my IgA nephropathy...

  43. 3 Lab Numbers That Predict Kidney Failure in IgA Nephropathy

    3 lab numbers can predict if you'll need dialysis in 10 years—and most IgA Nephropathy patients aren't tracking them correctly. In this episode, I break down the exact labs my IgAN patients monitor to prevent kidney failure. I'll show you how to read your lab report, explain the MEST-C biopsy...

  44. What's REALLY Causing Blood in Your Urine After a Cold

    Blood in the urine after a cold could be the first sign of IgA nephropathy—the most common kidney disease you've never heard of. This is Episode 1 of a comprehensive series where I break down everything you need to know about diagnosis, treatment, and prognosis. In this episode, I explain what…

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  45. Keto's Hidden Danger: Liver & Pancreas Damage While Staying Thin

    Strict ketogenic diets keep you thin—but what's happening inside your liver, pancreas, and kidneys? A groundbreaking 2025 study in Science Advances followed mice on strict ketogenic diets for nearly a year and revealed a disturbing metabolic paradox: while preventing weight gain, long-term keto...

  46. Kidney Test Lying to You? 2025 Breakthrough Revealed

    Spotify Description for Kidney Health AMA 2025 Your kidney test might be lying. A landmark 2025 JAMA study of 860,000 patients reveals when standard creatinine tests fail to detect early kidney disease—and what nephrologists now use instead. Plus: scientists discover "emergency cells" that could...

  47. Ozempic Not Working? Why 25% See No Weight Loss (Fix This)

    1 in 4 people on Ozempic lose almost NO weight—discover why GLP-1 medications fail for 25% of patients and what to do about it. If you're taking Ozempic, Wegovy, Mounjaro, or Zepbound and seeing minimal weight loss, this episode reveals exactly why—and how to fix it. One in four patients are...

  48. PKD: 1 in 500 Have It (Most Don't Know Until Too Late) | Inherited Kidney Disease Explained

    PKD affects 1 in 500 people—here's what you need to know to protect your kidneys. Polycystic Kidney Disease is the most common inherited cause of kidney failure, but 90% of people don't discover they have it until kidneys are already damaged. In this episode, board-certified Nephrologist Dr. Sean...

  49. Part 4: 4 Medications That Stop Diabetic Kidney Failure

    4 medications that stop diabetic kidney failure—yet most doctors aren't prescribing them. Here's why you might be getting 1990s care in 2025. In Part 4, I reveal a 49-year-old diabetic patient with kidney function of 24 and massive protein spillage—prepared for dialysis—but only on outdated 1990s...

  50. Part 3: Diabetic Kidney Damage Reversed: Stage 3A to Normal

    Can diabetic kidney damage actually be reversed? This shocking case proves it's possible. In Part 3 of our diabetic kidney disease series, I reveal a real patient case that challenges everything you've been told about "irreversible" kidney damage. A 43-year-old woman with stage 3A diabetic kidney...

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ABOUT THIS SHOW

Understand your kidney numbers and metabolic health. I'm Dr. Sean Hashmi, a board-certified kidney and obesity medicine specialist. I explain the research behind your lab results, food choices and daily habits in plain English.I'm the founder of SELF Principle, a nonprofit built around Sleep, Exercise, Love and Food.Free weekly newsletter: https://selfprinciple.org/newsletter/Website: https://www.seanhashmimd.com/For education only, not personal medical advice.

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Sean Hashmi, MD

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Sean Hashmi, MD currently has 77 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

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Understand your kidney numbers and metabolic health. I'm Dr. Sean Hashmi, a board-certified kidney and obesity medicine specialist. I explain the research behind your lab results, food choices and daily habits in plain English.I'm the founder of SELF Principle, a nonprofit built around Sleep,...

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Sean Hashmi, MD has 77 episodes. Check the episode list to see recent publication dates and frequency.

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