PODCAST · education
Step 1 Basics (USMLE)
by Sam Smith
USMLE Step 1 audio lessons designed to be listened to over and over again. Episodes cover material from many different areas including the cardiovascular system, pulmonary system, microbiology, and more! Listen when at the gym, commuting, cooking, or whenever you are on the go.Episodes are written, recorded, and mixed by Sam Smith.
Episodes
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Rheum| Antibody Review
4.11 Antibody Review Rheumatology review for the USMLE Step 1 Exam. ANA Principles ANA (Anti-Nuclear Antibody): Non-specific antibody. Reacts against nuclear antigens, including proteins, DNA, RNA, and nucleic acid-protein complexes. Includes a group of antibodies such as anti-dsDNA…
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Rheum| Gout and Pseudogout
4.10 Gout and Pseudogout Rheumotology review for the USMLE Step 1 Exam. Gout Caused by uric acid crystal deposition due to purine metabolism. Triggers inflammation when crystals precipitate in cooler joint fluid. Presents with severe, red, and swollen monoarticular joints, often in the big toe....
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Rheum| Rheumatologic Emergencies
4.09 Rheumatologic Emergencies Rheumatology review for USMLE Step 1 Exam Giant Cell Arteritis (GCA) A large vessel vasculitis, mainly in older individuals. Symptoms: headache, jaw claudication, vision loss. Ischemia from granulomas in large vessels causes vision loss. Immediate high-dose...
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Cardio| Systolic Heart Murmurs
1.06 Systolic Heart Murmurs Cardiovascular system review for the USMLE STEP 1 Exam Heart murmurs are caused by turbulent blood flow in the heart There are 4 different types of systolic murmurs: ventricular septal defect (VSD), patent ductus arteriosus (PDA), aortic stenosis, and mitral or…
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Psych| OCD and Related Disorders
5.13 OCD and Related Disorders Psych review for the USMLE Step 1 Exam Obsessive Compulsive Disorder (OCD): Unwanted thoughts (obsessions) and repetitive behaviors (compulsions). Treat with CBT + SSRIs/SNRIs. Tic Disorders: Tourette Syndrome involves multiple motor and at least one vocal tic.…
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Psych| Anxiety Related Disorders
5.12 Anxiety Related Disorders Psychiatry review for the USMLE Step 1 Exam Anxiety is a normal response to threats or stressors in the environment Anxiety disorders occur when anxiety causes significant distress or impairment in functioning Generalized Anxiety Disorder (GAD) involves persistent…
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Psych| Eating and Feeding Disorders
5.11 Eating and Feeding Disorders Psychiatry Review for the USMLE Step 1 Exam Eating Disorders: Main disorders: bulimia nervosa, anorexia nervosa, and binge eating disorder. Bulimia and anorexia share anxiety and compensatory behaviors. Anorexia: low body weight, fear of gaining weight, treatment...
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Psych| Mood Disorders (Grief, Depression, and Bipolar)
5.10 Mood Disorders (Depression and Bipolar) Psychiatry Review for the USMLE Step 1 exam Mood disorders are persistent disruptions in emotion, categorized into bipolar disorders and depressive disorders. Bipolar disorders are characterized by manic or hypomanic episodes, while depressive…
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Psych| Schizophrenia
5.09 Schizophrenia Psychiatry review for the USMLE Step 1 Exam Epidemiology: Slight male predilection (1.4:1 male to female ratio). Men present between 18-25, women between 28-35. Affects about 0.5% of the population. Symptoms: Positive symptoms: hallucinations, delusions, disorganized behavior…
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Psych| Cluster C Personality Disorders
5.08 Cluster C Personality Disorders Psychiatry review for the USMLE Step 1 Exam Introduction: Cluster C personality disorders = anxious/worried. Disorders: avoidant, obsessive-compulsive, dependent. Distinguish from normal traits. Avoidant Personality Disorder: Inhibited, introverted, anxious....
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Psych| Cluster B Personality Disorders
5.07 Cluster B Personality Disorders Psychiatry review for USMLE Step 1 Exam Cluster B personality disorders are the highest yield among all personality disorders. The cluster B disorders include borderline personality disorder, histrionic personality disorder, narcissistic personality disorder,...
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Psych| Cluster A Personality Disorders
5.06 Cluster A Personality Disorders Psychiatry review for the USMLE Step 1 Exam. The cluster A personality disorders include paranoid, schizoid, and schizotypal. These disorders are characterized by individuals who are perceived as weird, awkward, and quiet. Personality disorders differ from...
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Psych| Hallucinogens (Types, Intoxication, and Withdrawal)
5.05 Hallucinogens (Types, Intoxication, and Withdrawal) Psychiatry review for the USME STEP 1 Exam. Hallucinogens are a diverse class of drugs that cause hallucinations and other symptoms. Common hallucinogens discussed in the podcast are LSD, marijuana, PCP, and ketamine. LSD activates…
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Psych| Depressants (Types, Intoxication, and Withdrawal)
5.04 Depressants (Types, Intoxication, and Withdrawal) Psychiatry review for the USMLE Step 1 exam. Depressants decrease neuronal activity in the brain. They can work by stimulating GABAergic neurons or binding to opiate receptors. Common GABA-promoting depressants: alcohol, benzodiazepines,...
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Psych| Stimulants (Types, Intoxication, and Withdrawal)
5.03 Stimulants (Types, Intoxication, and Withdrawal) Psychiatry review for the USMLE Step 1 Exam. Stimulants increase CNS activity and activate the sympathetic nervous system. They can block reuptake of neurotransmitters or stimulate their release. Intoxication symptoms include agitation…
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Psych| Classical and Operant Conditioning
5.02 Classical and Operant Conditioning Psychiatry review for the USMLE Step 1 Exam Classical Conditioning: Pavlovian conditioning discovered by Ivan Pavlov, a Russian physiologist known for his experiments with dogs. Learning through association. Example: Conditioning dogs to respond to a noise...
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Psych| Ego Defenses
5.01 Ego Defenses Psychiatry review for the USMLE Step 1 Exam Defense mechanisms protect the unconscious part of our personality from anxiety caused by unacceptable thoughts or feelings. Ego defenses are categorized into three groups: mature, neurotic, and immature. Immature defense mechanisms...
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Rhem| Myasthenia Gravis and Lambert Eaton Syndrome
4.08 Myasthenia Gravis and Lambert Eaton Syndrome MSK/Rheumatology review for the USMLE Step 1 Exam Introduction: Review of neuromuscular junction and its components: presynaptic part, postsynaptic part, synaptic cleft. Cascade of events leading to the release of acetylcholine into the synaptic...
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HIGH YIELD 3: Schizophrenia Spectrum and Psychotic Disorders
This high yeild podcast covers schizophrenia type disorders for the USMLE Step 1 exam. I cover the following topics: Defining psychotic symptoms: hallucinations, delusions, and disorganized thoughts/speech Example of a delusional belief about a small being inside the body Schizophrenia spectrum...
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Rheum| Polymyositis and Dermatomyositis
4.07 Polymyositis and Dermatomyositis MSK/Rheum review for the USMLE Step 1 Exam Polymyositis and dermatomyositis are autoimmune inflammatory myopathies. They are caused by abnormal activation of T cells that attack skeletal muscle and both cause proximal muscle weakness, especially of the...
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Rheum| Rheumatoid Arthritis vs Osteoarthritis
4.06 Osteoarthritis vs Rheumatoid Arthritis Rheumatology review for the USMLE Step 1 exam Rheumatoid arthritis and osteoarthritis both cause joint inflammation, joint pain, and can limit joint range of motion Osteoarthritis is a degenerative joint disease that occurs when the articular cartilage...
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Rheum| Scleroderma
4.05 Scleroderma Rheumatology review for the USMLE Step 1 exam Scleroderma is a chronic autoimmune connective tissue disease that causes thickening and hardening of the skin, as well as fibrosis (excess deposition of collagen and other ECM proteins) throughout the body. Autoreactive immune cells...
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HIGH YIELD 2: Marfan's vs Homocystinuria vs Ehlers-Danlos
HIGH YIELD 2: Marfan's vs Homocystinuria vs Ehlers-Danlos High yield review for the USMLE Step 1 exam. Marfan's syndrome, Ehlers-danlos, and homocystinuria are three distinct diseases that affect connective tissue. They share similarities like tall stature, long fingers, scoliosis, high arched...
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Rheum| Systemic Lupus Erythematosus
4.04 Systemic Lupus Erythematosus Rheumatology review for the USMLE Step 1 Exam Marfan's syndrome, Ehlers-danlos, and homocystinuria are three distinct diseases that affect connective tissue. They share some clinical features like tall stature, long fingers, scoliosis, high arched pallet, chest...
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Rheum| Large Vessel Vasculitis
4.03 Large Vessel Vasculitis Rheumatology review for the USMLE Step 1 Exam Vasculitis is inflammation of blood vessels Vasculitis is split into three groups based on the size of blood vessels affected: large, medium, and small vessel vasculitis Large vessel vasculitis involves inflammation of the...
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Rheum| Medium Vessel Vasculitis
4.02 Medium Vessel Vasculitis Rheumatology review for the USMLE Step 1 exam. Vasculitis: inflammation of blood vessels, classified by the size of the blood vessels affected Medium vessel vasculitis affects the main visceral arteries and veins, and their initial branches Three types of medium…
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Rheum| Small Vessel Vasculitis
4.01 Small Vessel Vasculitis Rheumatology review for the USMLE Step 1 exam Vasculitis is inflammation of blood vessels and is classified into three categories based on vessel size: large, medium, and small vessel vasculitis. Small vessel vasculitis affects arterioles, capillaries, and venules,...
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HIGH YIELD 1: Top Weird Drug Reactions
HIGH YIELD 1: Top Weird Drug Reactions Review for the USMLE Step 1 exam The podcast discusses high yield weird drug side effects that are unexpected. Cyanopsia (blue vision) with sildenafil (PDE-5 inhibitor) Hepatic necrosis with halothane (inhaled anesthetic) Tendon/cartilage damage with...
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Micro| Spirochetes
3.30 Spirochetes Microbiology review for the USMLE Step 1 Exam Spirochetes are spiral or corkscrew-shaped bacteria that stain gram negative. They have a unique endoflagella that distinguishes them from other species of bacteria. The endoflagella rotates within the periplasmic space and causes the...
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Micro| Mycoplasma and Ureaplasma
3.29 Mycoplasma and Ureaplasma Microbiology review for the USMLE Step 1 Exam Mycoplasma and Ureaplasma are bacteria without cell walls, making them invisible to gram stain. They cause respiratory and genital infections and have a cell membrane containing cholesterol. Main species causing…
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Micro| Klebsiella Pneumoniae
3.28 Klebsiella Pneumoniae Microbiology review for the USMLE Step 1 Exam Klebsiella pneumoniae is a lactose-fermenting, gram-negative bacilli that causes pneumonia and is part of the normal GI flora in humans. It causes infection when introduced to the respiratory tract and is commonly found in...
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Micro| Chlamydia Species
3.27 Chlamydia Species Microbiology review for the USMLE Step 1 exam Chlamydia is a gram-negative bacteria that is an obligate intracellular organism. It has a two-part life cycle involving the reticular body (active form) and elementary body (inactive form). There are three main species of...
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Micro| Pseudomonas Aeruginosa
3.26 Pseudomonas Aeruginosa Microbiology review for the USMLE Step 1 Exam Pseudomonas aeruginosa is an encapsulated gram-negative oxidase positive rod that causes a variety of diseases. It can be found in soil, hospitals, and water, and it particularly likes water. P. aeruginosa can enter the…
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Micro| Proteus Species
3.25 Proteus Species Microbiology review for the USMLE Step 1 exam Proteus species are gram-negative rods that cause hospital acquired urinary tract infections They have swarming motility and can move quickly in a coordinated fashion across surfaces due to their numerous flagella They can...
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Micro| Salmonella Species
3.24 Salmonella Species Microbiology review for the USMLE Step 1 Exam Salmonella are gram-negative bacteria that cause gastrointestinal disease. They have flagella that enable them to move around and infect cells, and can live inside macrophages. There are two categories of salmonella species:...
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Micro| Yersinia Species
3.23 Yersinia Species Microbiology review for the USMLE Step 1 Exam Yersinia are gram-negative, non-motile bacteria that cause zoonotic diseases. Yersinia produce urease enzyme to survive in the stomach and are facultative intracellular bugs. Three species of yersinia causing disease in humans…
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Micro| Escherichia Coli (E. Coli)
3.22 Escherichia Coli (E. Coli) Microbiology review for the USMLE Step 1 Exam Esherichia coli (E. coli) is a lactose-fermenting, gram-negative rod causing various diseases, ranging from mild gastroenteritis to septic shock. E. coli diseases can be divided into two categories: intestinal…
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Pulm| Tuberculosis
2.22 Tuberculosis Pulmonary system review for the USMLE Step 1 Exam Tuberculosis is caused by Mycobacterium tuberculosis bacteria and mainly affects the lungs. It is more common in developing countries, with India, Indonesia, China, Nigeria, Pakistan, and South Africa having the most TB deaths...
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Pulm| Pneumonia: Lobar, Broncho, and Interstitial
2.21 Pneumonia: Lobar, Broncho, and Interstitial Pulmonary system review for the USMLE Step 1 Exam Pneumonia is an infection of the lung parenchyma that deals with gas exchange Three classic patterns of pneumonia: lobar, bronchopneumonia, and interstitial pneumonia Lobar pneumonia involves a…
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Pulm| Pneumothorax
2.20 Pneumothorax Pulmonary system review for the USMLE Step 1 Exam Pneumothorax is a collection of air outside the lung in the pleural cavity, caused by a hole in the pleurae that allows air to infiltrate and disturb normal respiratory function. There are three categories of causes: primary...
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Pulm| Pleural Effusions: Transudate vs Exudate
2.19 Pleural Effusions: Transudate vs Exudate Pulmonary system review for the USMLE Step 1 Exam Pleural effusion is an abnormal accumulation of fluid in the pleural cavity. Pleural effusions can be characterized as either exudative or transudative based on the content of the extra fluid.…
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Pulm| Digital Clubbing
2.18 Digital Clubbing Pulmonary system review for the USMLE Step 1 Exam Digital clubbing is the enlargement of the ends of fingers and toes due to growth of connective tissue between the nail matrix and the distal portion of the digit. It is defined quantitatively as an increased angle between…
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Pulm| Pickwickian Syndrome (Obesity Hypoventilation Syndrome)
2.17 Pickwickian Syndrome Pulmonary system review for the USMLE Step 1 Exam Pickwickian Syndrome is also called obesity hypoventilation syndrome Characterized by daytime hypoventilation leading to hypercapnia Often occurs in individuals with a BMI over 30 Excess fat puts pressure on lungs and...
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Pulm| Sleep Apnea
2.16 Sleep Apnea Pulmonary system review for the USMLE Step 1 Exam Sleep apnea is the repeated severe decrease or cessation of airflow into the lungs for more than 10 seconds during sleep, which causes the person to stop breathing for more than 10 seconds while they're sleeping. There are two…
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Pulm| Pulmonary Hypertension
2.15 Pulmonary Hypertension Pulmonary system review for the USMLE Step 1 Exam Pulmonary hypertension is elevated blood pressure within the pulmonary arteries at rest, defined as a mean pulmonary artery pressure above 20 mmHg. Primary pulmonary hypertension is high blood pressure in the pulmonary...
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Pulm| Acute Respiratory Distress Syndrome (ARDS)
2.14 Acute Respiratory Distress Syndrome (ARDS) Pulmonary system review for the USMLE Step 1 Exam Acute respiratory distress syndrome (ARDS) is an acute, diffuse, inflammatory form of lung injury that is life-threatening for patients. ARDS is a response from the lungs to severe injury, most...
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Pulm| Sarcoidosis
2.13 Sarcoidosis Pulmonary system review for the USMLE Step 1 Exam Sarcoidosis is a multisystem inflammatory disorder with non-caseating granulomas in various organs Most commonly affects the lungs and causes restrictive lung disease Classic patient is a young black female in her 20-30s, but can...
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Micro| Helicobacter Pylori
3.21 H. Pylori Microbiology review for the USMLE Step 1 exam Helicobacter Pylori (H. Pylori) is a gram-negative, comma-shaped bacteria that causes chronic gastritis Estimated that 50% of people worldwide are infected with H. Pylori; higher in developing countries, lower in developed countries…
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Micro| Vibrio Species
3.20 Vibrio Species Microbiology review for the USMLE Step 1 Exam Vibrio species are gram negative comma-shaped rods with a single flagellum, allowing them to move quickly Two main species that cause human infections: Vibrio cholerae and Vibrio vulnificus Vibrio cholerae causes foodborne disease...
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Micro| Campylobacter Jejuni
3.19 Campylobacter Jejuni Microbiology review for the USMLE Step 1 exam Campylobacter jejuni is a gram-negative, comma-shaped bacteria that causes diarrheal illness It is the most common cause of bacterial diarrhea in the US It can be distinguished from other gram-negative, comma-shaped bacteria…
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ABOUT THIS SHOW
USMLE Step 1 audio lessons designed to be listened to over and over again. Episodes cover material from many different areas including the cardiovascular system, pulmonary system, microbiology, and more! Listen when at the gym, commuting, cooking, or whenever you are on the go.Episodes are written, recorded, and mixed by Sam Smith.
HOSTED BY
Sam Smith
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Step 1 Basics (USMLE) currently has 117 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Step 1 Basics (USMLE) about?
USMLE Step 1 audio lessons designed to be listened to over and over again. Episodes cover material from many different areas including the cardiovascular system, pulmonary system, microbiology, and more! Listen when at the gym, commuting, cooking, or whenever you are on the go.Episodes are written,...
How often does Step 1 Basics (USMLE) release new episodes?
Step 1 Basics (USMLE) publishes regularly with 117 episodes available. Check the episode list for the typical release schedule.
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Who hosts Step 1 Basics (USMLE)?
Step 1 Basics (USMLE) is created and hosted by Sam Smith.
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