The Abstract Podcast: Small Animal Oncology

Small Animal Oncology: June 14th 2026 (abstracts published between 7th June and 13th June 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:01:03) Pope and colleagues, Veterinary and comparative oncology, "Use of the IlluminOss Photodynamic Bone Stabilisation System Following Stereotactic Body Radiation Therapy for Limb-Sparing in Six Dogs With Presumptive Appendicular Osteosarcoma.", https://doi.org/10.1111/vco.70082 ----- • (00:03:54) Mizuno and colleagues, American journal of veterinary research, "Survival outcomes in canine nasal tumors treated with megavoltage radiation therapy with or without toceranib phosphate: a retrospective study of 279 cases.", 1-5, https://doi.org/10.2460/ajvr.26.03.0135 ----- • (00:05:33) Nascimento and colleagues, BMC veterinary research, "Pilot evaluation of a liquid biopsy test for longitudinal monitoring of disease status in dogs undergoing treatment for multicentric lymphoma.", https://doi.org/10.1186/s12917-026-05599-1 ----- • (00:06:52) Megquier and colleagues, Communications medicine, "Impact of preanalytical factors on liquid biopsy in the canine cancer model.", https://doi.org/10.1038/s43856-026-01630-6 ----- • (00:09:39) Nemoto and colleagues, The Journal of veterinary medical science, "Comparison of three irradiation ways with Monte Carlo calculation for the feline lymphoma with orthovoltage radiation therapy.", https://doi.org/10.1292/jvms.25-0305 ----- • (00:08:03) Leitão and colleagues, Vaccine, "Autologous tumor-based vaccines in canine oncology: a systematic review of safety, immunogenicity, and therapeutic potential.", Vol 88, pp. 128836, https://doi.org/10.1016/j.vaccine.2026.128836 ----- • (00:02:32) Ehara and colleagues, Veterinary surgery : VS, "Clinical outcomes of laparoscopic hepatectomy using en bloc hilar pedicle control in dogs with hepatic masses.", https://doi.org/10.1111/vsu.70124 ----- Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way. To suggest improvements or report problems please write to [email protected]

Small Animal Oncology: June 7th 2026 (abstracts published between 31st May and 6th June 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:01:08) Johnson and colleagues, Veterinary and comparative oncology, "Recurrence Rates for Mandibular Fibrosarcoma Associated With Mandibular Canal Invasion Following Mandibulectomy Procedures in Dogs.", Vol 24, pp. 407-415, https://doi.org/10.1111/vco.70064 ----- • (00:02:53) Machado and colleagues, Veterinary and comparative oncology, "Mediastinal Lymphoma in 70 Dogs Treated With Lomustine or Anthracycline-Based Multi-Agent Chemotherapy.", Vol 24, pp. 382-392, https://doi.org/10.1111/vco.70062 ----- • (00:06:11) Jeon and colleagues, Veterinary and comparative oncology, "Transarterial Embolisation as Palliative Therapy for Oral Tumours in Canine and Feline Patients: A Retrospective Case Series.", Vol 24, pp. 248-259, https://doi.org/10.1111/vco.70043 ----- • (00:04:31) Rossmeisl and colleagues, Veterinary and comparative oncology, "Prognostic Value of Magnetic Resonance Imaging Defined Extent of Surgical Resection in Dogs With Intracranial Meningiomas.", Vol 24, pp. 260-273, https://doi.org/10.1111/vco.70044 ----- • (00:09:39) Choi and colleagues, American journal of veterinary research, "Recurrent pyuria is associated with shorter progression-free survival in dogs with bladder urothelial carcinoma.", 87, https://doi.org/10.2460/ajvr.25.12.0438 ----- • (00:07:59) Hanai and colleagues, Veterinary journal (London, England : 1997), "PD-L2 reverse signaling suppresses tumor cell proliferation and serves as a prognostic indicator in canine high-grade mast cell tumors.", Vol 317, pp. 106710, https://doi.org/10.1016/j.tvjl.2026.106710 ----- • (00:11:09) Aluai-Cunha and colleagues, Research in veterinary science, "Linking faecal microbiota changes to clinical and prognostic features in dogs with mast cell tumours through 16S rRNA gene sequencing.", Vol 204, pp. 106124, https://doi.org/10.1016/j.rvsc.2026.106124 ----- Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way. To suggest improvements or report problems please write to [email protected]

Small Animal Oncology: May 31st 2026 (abstracts published between 24th May and 30th May 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:00:57) Olsen and colleagues, Veterinary and comparative oncology, "Messenger RNA From Canine Cytology Lymph Node Specimens Can Be Utilised for Gene Expression Profiling Using Digital RNA Counting.", https://doi.org/10.1111/vco.70078 ----- • (00:02:26) Bhanpattanakul and colleagues, Veterinary journal (London, England : 1997), "Clinicopathologic and Immunophenotypic Characterization of Canine Cutaneous Mast Cell Tumors: Associations With Tumor Grade and the Tumor-Immune Microenvironment.", 106713, https://doi.org/10.1016/j.tvjl.2026.106713 ----- • (00:03:52) Rigo and colleagues, The Journal of small animal practice, "Intraoperative use of N-butyl cyanoacrylate for haemostasis following cavotomy for tumour thrombus removal in dogs undergoing adrenalectomy.", https://doi.org/10.1111/jsap.70146 ----- • (00:05:08) Shi and colleagues, BMC veterinary research, "Canine mammary tumors: a bibliometric and visualized analysis from 2009 to 2025.", https://doi.org/10.1186/s12917-026-05601-w ----- • (00:06:07) He and colleagues, Cancer research communications, "Nanoparticulate Immunoactive Complex (IMAX) for local chemoimmunotherapy: From murine models to pilot canine study.", https://doi.org/10.1158/2767-9764.CRC-26-0110 ----- • (00:07:23) Khodari and colleagues, Journal of feline medicine and surgery, "EXPRESS: Ultrasonographic findings of feline large intestinal adenocarcinoma and high-grade lymphoma.", 1098612X261458018, https://doi.org/10.1177/1098612X261458018 ----- • (00:08:40) Galbiati and colleagues, Journal of medicinal chemistry, "A Small-Molecule Drug Conjugate Targeting FAP Exhibits Potent Activity in Dogs with Spontaneous Tumors.", Vol 69, pp. 12634-12646, https://doi.org/10.1021/acs.jmedchem.6c00682 ----- • (00:10:01) Lyu and colleagues, Scientific reports, "A canine macrophage cell line that can be polarized provides a model for canine macrophage differentiation.", https://doi.org/10.1038/s41598-026-52770-7 ----- • (00:11:16) Kudo and colleagues, The Journal of veterinary medical science, "Histopathological analysis of oral epithelial dysplasia in pericancerous epithelium of lingual squamous cell carcinoma of dogs and cats.", https://doi.org/10.1292/jvms.25-0309 ----- • (00:12:32) Jeon and colleagues, The veterinary quarterly, "Leverage of quick-soluble gelatin microparticles in transarterial chemoembolization of canine urothelial carcinomas.", Vol 46, pp. 2679557, https://doi.org/10.1080/01652176.2026.2679557 ----- Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way. To suggest improvements or report problems please write to [email protected]

Small Animal Oncology: May 24th 2026 (abstracts published between 17th May and 23rd May 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:01:00) Akbari-Ardabili and colleagues, Veterinary and comparative oncology, "Cross-Species Transcriptomic and Network Analysis of Human and Canine Diffuse Large B-Cell Lymphoma Identifies a Conserved Replication-DNA Damage Module for Drug Repurposing.", https://doi.org/10.1111/vco.70079 ----- • (00:04:48) Bronko and colleagues, Journal of the American Veterinary Medical Association, "Frozen section biopsy is a feasible and accurate tool for diagnosing canine and feline oral tumors in a private veterinary oral surgery practice.", 1-8, https://doi.org/10.2460/javma.26.03.0204 ----- • (00:05:55) Hanai and colleagues, Veterinary journal (London, England : 1997), "PD-L2 reverse signaling suppresses tumor cell proliferation and serves as a prognostic indicator in canine high-grade mast cell tumors.", Vol 317, pp. 106710, https://doi.org/10.1016/j.tvjl.2026.106710 ----- • (00:07:15) Janik and colleagues, The Veterinary record, "Thrombocytosis and tumour distribution predict outcome in dogs with hepatocellular carcinoma: A multi-institutional retrospective analysis.", https://doi.org/10.1002/vetr.70732 ----- • (00:08:35) Giglia and colleagues, Acta neuropathologica communications, "Pituitary blastoma in a dog: comparative clinical, imaging, and pathologic features of a newly recognized and rare human entity.", https://doi.org/10.1186/s40478-026-02281-3 ----- • (00:09:41) Arora and colleagues, Acta veterinaria Hungarica, "The emerging importance of TNF-α in canine mammary cancer: A narrative overview.", https://doi.org/10.1556/004.2026.01280 ----- • (00:10:41) García and colleagues, Domestic animal endocrinology, "Qualitative and quantitative assessment of thyroid scintigraphy in 536 hyperthyroid cats from Argentina.", Vol 97, pp. 107023, https://doi.org/10.1016/j.domaniend.2026.107023 ----- • (00:02:23) Pal and colleagues, Journal of vascular and interventional radiology : JVIR, "Irreversible Electroporation of Spine Tumors in a Canine Model: Tumoricidal Effects and Neural Toxicity.", 108857, https://doi.org/10.1016/j.jvir.2026.108857 ----- • (00:03:38) Riddile and colleagues, Journal of veterinary dentistry, "Modified T-Shaped Closure of Rostral Maxillary Defects in Dogs Following Rostral Maxillectomy.", 8987564261450510, https://doi.org/10.1177/08987564261450510 ----- To suggest improvements or report problems please write to [email protected] Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way.

Small Animal Oncology: May 17th 2026 (abstracts published between 10th May and 16th May 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:01:01) Sakuma and colleagues, Veterinary and comparative oncology, "Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines.", https://doi.org/10.1111/vco.70077 ----- • (00:04:26) Pottenger and colleagues, Advanced drug delivery reviews, "Cowpea mosaic virus as a candidate for intratumoral immunotherapy: progress, challenges, and future directions.", 115894, https://doi.org/10.1016/j.addr.2026.115894 ----- • (00:05:32) Ducharme and colleagues, American journal of physiology. Cell physiology, "Dietary supplementation with ursolic acid preserves skeletal muscle mass and strength in mouse models of cancer cachexia.", https://doi.org/10.1152/ajpcell.00159.2026 ----- • (00:06:34) DiBenedetto and colleagues, BMC research notes, "Cytomorphologic changes in blood erythrocytes, leukocytes, and platelets in dogs progressing through CHOP therapy to treat multicentric lymphoma.", https://doi.org/10.1186/s13104-026-07870-y ----- • (00:07:48) Herman and colleagues, BMC veterinary research, "Multimodal treatment of canine lower eyelid mast cell tumours: lip-to-lid reconstruction and sentinel lymph node mapping in two cases.", https://doi.org/10.1186/s12917-026-05420-z ----- • (00:08:54) Turner and colleagues, BMC veterinary research, "Abdominal visceral to subcutaneous fat distribution in dogs: computed tomography accuracy and factors associated with distribution.", https://doi.org/10.1186/s12917-026-05503-x ----- • (00:10:05) Araújo-Júnior and colleagues, Journal of comparative pathology, "Presumed monoclonal gammopathy and parasitized immune cells in peritoneal fluid of a dog with canine leishmaniasis.", Vol 227, pp. 73-76, https://doi.org/10.1016/j.jcpa.2026.05.002 ----- • (00:10:59) Morais de Almeida and colleagues, Journal of feline medicine and surgery, "EXPRESS: Clinical and virological effects of the integrase inhibitor raltegravir in cats with naturally progressive feline leukaemia virus infection.", 1098612X261452556, https://doi.org/10.1177/1098612X261452556 ----- • (00:02:08) Stocklein and colleagues, Veterinary pathology, "Histomorphologic and immunohistochemical characteristics of intraocular metastatic carcinomas of presumed pulmonary origin in cats: A retrospective case series from 2019 to 2025.", 3009858261445996, https://doi.org/10.1177/03009858261445996 ----- • (00:03:26) Yavas and colleagues, Veterinary pathology, "Changes in mast cell density, fibrosis, and immunohistochemical expression of tryptase, chymase, SCF, and PAR2 during regression of canine transmissible venereal tumors.", 3009858261445994, https://doi.org/10.1177/03009858261445994 ----- To suggest improvements or report problems please write to [email protected] Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way.

Small Animal Oncology: May 10th 2026 (abstracts published between 3rd May and 9th May 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:00:53) Hauer and colleagues, Journal of veterinary internal medicine, "Lumbar spinal cord ganglioglioma in a 2-year-old Boxer dog.", 40, https://doi.org/10.1093/jvimsj/aalag081 ----- • (00:04:20) Darrah and colleagues, American journal of veterinary research, "Magnetic resonance imaging of dogs with cervical disease revealed a higher proportion of intervertebral disk disease in small dogs and neoplasia in large dogs.", 1-8, https://doi.org/10.2460/ajvr.25.12.0450 ----- • (00:05:29) Rosa-Padilla and colleagues, American journal of veterinary research, "Persistent and recurrent hypercalcemia are uncommon in dogs undergoing surgical treatment for primary hyperparathyroidism.", 1-9, https://doi.org/10.2460/ajvr.26.03.0104 ----- • (00:06:41) Westman and colleagues, Journal of feline medicine and surgery, "EXPRESS: Antibody responses to inactivated (adjuvanted) and attenuated (non-adjuvanted) feline panleukopenia virus vaccination, including in different injection sites.", 1098612X261450889, https://doi.org/10.1177/1098612X261450889 ----- • (00:02:02) Peres and colleagues, Veterinary clinical pathology, "What Is Your Diagnosis? Blood Smear From a Mixed-Breed Dog.", https://doi.org/10.1111/vcp.70111 ----- • (00:03:02) Neal and colleagues, Veterinary clinical pathology, "Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma.", https://doi.org/10.1111/vcp.70112 ----- • (00:08:02) Orhan and colleagues, Veterinary immunology and immunopathology, "Determination of oxidative DNA damage and i̇nflammation in the differentiation grades of feline squamous cell carcinomas: The role of Nrf2/HO-1/Keap1 and TLR4/NF-κB/COX-2/ICAM-1 pathways.", Vol 298, pp. 111133, https://doi.org/10.1016/j.vetimm.2026.111133 ----- • (00:09:22) Ziółkowska and colleagues, Veterinary research communications, "Oculodermal melanocytosis (Nevus of Ota) in a Great Dane with concurrent ocular abnormalities: a case report.", 50, https://doi.org/10.1007/s11259-026-11243-y ----- To suggest improvements or report problems please write to [email protected] Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way.

Small Animal Oncology: May 3rd 2026 (abstracts published between 26th April and 2nd May 2026) Welcome to The Abstract Podcast! In this episode, Alex and Sarah review the latest veterinary literature. ### Papers Discussed Today: • (00:04:30) Gustafson and colleagues, Veterinary and comparative oncology, "Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers.", https://doi.org/10.1111/vco.70074 ----- • (00:06:14) Aluisio and colleagues, Journal of the American Veterinary Medical Association, "Cytology and histopathology have poor to fair agreement for determination of neoplastic or nonneoplastic lesions in dogs with splenic masses or nodules.", 1-5, https://doi.org/10.2460/javma.26.01.0006 ----- • (00:08:04) Bak-Jacobsen and colleagues, American journal of veterinary research, "Platelet-derived extracellular vesicles expressing phosphatidyl serine associate with benign and malignant neoplasia and regional metastasis in dogs: a study of 113 dogs.", 87, https://doi.org/10.2460/ajvr.25.10.0358 ----- • (00:09:56) Nance-Richey and colleagues, Communications biology, "Spatial transcriptomic mapping of canine osteosarcoma reveals immune microenvironment features linked to survival.", https://doi.org/10.1038/s42003-026-10152-9 ----- • (00:01:01) Uno and colleagues, Journal of the American Animal Hospital Association, "Treatment Outcomes and Tolerability of Postoperative Radiotherapy in 10 Dogs with Spinal Meningiomas.", Vol 62, pp. 108-114, https://doi.org/10.5326/JAAHA-MS-7498 ----- • (00:02:41) Gordon and colleagues, Veterinary surgery : VS, "Investigation of the "R" tumor margin classification and prognostic factors in apocrine gland anal sac adenocarcinoma of dogs.", Vol 55, pp. 744-751, https://doi.org/10.1111/vsu.70044 ----- To suggest improvements or report problems please write to [email protected] Produced by Marco Duz, MedVet MVM(Res) DipECEIM PhD SFHEA MRCVS. Marco is an EBVS and RCVS recognised Specialist in Equine Internal Medicine. He produces The Abstract Podcast to help veterinary professionals keep up with the scientific literature in a practical, accessible way.