PODCAST · education
The High-Yield Podcast
by Ardalan Vossoughi, MD
An Up-to-date Audio-Flashcards Review of Medicine
Episodes
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High-Yield Hepatobiliary & Pancreatic Disorders: Complications of Gallstone Disease (Cholangitis, Chronic cholecystitis, Gallstone Ileus, Porcelaine GB, Carcinomas)
Approach to workup of cholangitis, chronic cholecystitis, Gallstone Ileus, Cholangiocarcinoma including Klatskin tumor, Carcinoma of GB and Pancreas At the end some house-cleaning on iatrogenic complications of gallstone disease after ERCP and other procedures are discussed (including bile duct...
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High-Yield Hepatobiliary & Pancreatic Disorders: Cholecystitis (Calculous, Acalculous), Post-Cholecystectomy Syndrome & Sphincter of Oddy's Dysfunction
Question-based Review of Cholecystitis workup and management followed by addressing the complications of cholecystectomy.
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High-Yield Hepatobiliary & Pancreatic Disorders: Differential Diagnosis of Gallstone Disease (Cholelithiasis, Choledocholithiasis)
Both Pathophysiology and Clinical Aspects of gallstone disorders are discussed followed by important hints on differential diagnosis of gallstone disease from one another and from their complications, most specifically from cholecystitis and cholangitis.
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High-Yield Hepatobiliary & Pancreatic Disorders: Differential Diagnosis of Liver Tumor (Adenoma, Hemangioma, FNH, HCC)
Question-based review of workup for hepatic neoplasms.
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High-Yield Hepatobiliary & Pancreatic Disorders: Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis, Fatty Liver Disease (AFLD & NAFLD), Budd-Chiari Syndrome
Questions & cases regarding diagnostic workup and management for PBC, PSC, Alcoholic & Non-Alcoholic Fatty Liver Disease (steatosis, steatohepatitis), and Vascular Hepatopathy
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High-Yield Hepatobiliary & Pancreatic Disorders: Hemochromatosis & Wilson's Disease
High-Yield Question-based review & cases of conditions associated with abnormal iron & copper metabolism
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High-Yield Hepatobiliary & Pancreatic Disorders: Differential Diagnosis in Chronic Viral Hepatitis (Risk Factors, Serology, Extrahepatic Featreus, Prognosis)
Question-based review of differential diagnosis in chronic HBV vs HCV infection.
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High-Yield Hepatobiliary & Pancreatic Disorders: Cases of Hepatitis B (Serologic Markers, Pathophysiology)
High-Yield question-based review of cases in hepatitis B pathophysiology.
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High-Yield Hepatobiliary & Pancreatic Disorders: Acute Viral Hepatitis (A, D, E) Differential Diagnosis, Co-infection vs Superinfection, Post-exposure PPx, Management
Questions-based review of risk factors, differential diagnosis and management of acute viral hepatitis A, D , E . Included co-infection, Superinfection, diagnostic workup (screening and confirmatory) and management options with discussion of post-exposure prophylaxis for HAV infection.
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High-Yield Hepatobiliary & Pancreatic Disorders: Esophageal Varices & Hepatorenal Syndrome
High-Yield cases & Question-based Review of 2 important complications of Cirrhosis (SOAP format). (For other complications look at hepatic encephalopathy in Acute liver failure and for Peritonitis to the previous episode)
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High-Yield Hepatobiliary & Pancreatic Disorders: Ascites & Bacterial Peritonitis (spontaneous & secondary)
Following the SOAP approach, we review Subjective, Objective, Assessment & Plan for Ascites & Peritonitis. Exudative versus Transudative classification compared to new SAAG-based classification are discussed for differential diagnosis. Values of SAAG in relation to Protein content, Cell count…
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High-Yield Hepatobiliary & Pancreatic Disorders: Cirrhosis
Following our SOAP format we have a question-based discussion of Subjective (epidemiology, risk factors, patients complaints), Objective (PhEx findings, lab assessment results), Assessment (of possible etiologic differential diagnosis) and Plan for management of cirrhosis.
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High-Yield Hepatobiliary & Pancreatic Disorders: Acute Liver Failure, Hepatic Encephalopathy, Acetaminophen Toxicity
Question-based review of Acute liver failure, staging of hepatic encephalopathy (per clinical & EEG criteria), management of ALF with understanding of the severity criteria, Stage-based management of hepatic encephalopathy, Indications & Eligibility requirement for Liver transplantation, and a...
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High-Yield Hepatobiliary & Pancreatic Disorders: Liver Function Tests (Important Algorithmic Approach)
After an important question-based assessment of structural versus functional components of hepatocyte markers, we discuss high-yield cases of Hepatitic, cholestatic and mixed-pattern LFT abnormalities. This is prerequisite to entire liver & hepatobiliary system discussions.
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High-Yield & Not-to-Miss Cases of Respiratory Failure Management
Case-Based Review of Respiratory Failure Management. Please make sure you understand the indications & contraindications for supplemental versus active (invasive & non-invasive) modes of ventilatory support before going through cases.
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High-Yield Critical Care: Non-Invasive Ventilation (NIV: CPAP, BiPAP), Cases & Indications
Indications and contra-indications for common methods of non-invasive ventilation are discussed in quick question-based format with cases as a preparation to the next major episode (i.e. discussion of management options in different types & severities of respiratory failure)
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High-Yield Critical Care: Invasive Airway (Endotracheal Intubation, Cricothyrotomy, Tracheostomy: Indications & Casees)
Question-based and quick review of important subject of patients in need of invasive active airway intervention (as opposed to those who benefit from non-invasive intervention or those who just need supplemental oxygenation without a need for active airway). We discuss endotracheal intubation...
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High-Yield Critical Care: Airway Management & Respiratory Support (General Approach)
Basics of approach to patient in need of respiratory support and airway management. Question-Based Discussion of "Hierarchical Ladder of Respiratory Support", patient stratification based on indications & contraindications to different modalities of respiratory support. This provides initial...
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High-Yield Critical Care: Respiratory Faiure - 2 (Hypercapnic Failure)
Brief but high-yield question-based approach to differential diagnosis in hypercapnic failure. Analyzing the differentials and management options based on the formula of Alveolar Minute Ventilation: Alveolar Minute Ventilation = Respiratory Rate x (Tidal Volume - Dead Space Volume) VA = RR x...
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High-Yield Critical Care: Respiratory Failure - 1 (Hypoxemic, Non-Hypoxemic Hypoxic, Clinical Application of Formulas in Differential Diagnosis: A-a gradient, O2 Delivery, Fick's formulas, P/F ratio)
Discussion of initial workup, classification and differential diagnosis of hypoxia & Hypoxemic respiratory failure. 1- Please make sure you have the formulas ready in front of you (including PA-O2 formula, O2 delivery, O2 content and Fick's Formulas among others). 2- If you need to pause and…
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High-Yield Critical Care & Nephrology: Metabolic Alkalosis (Differential Diagnosis and Workup, Including Saline-Responsivevs & Unresponsive types, Liddle, Gitelman, Bartter, SAME)
Differential Diagnosis of metabolic Alkalosis and the overall approach to metabolic alkalosis with cases and step-up scenarios including Saline-Responsive and Unresponsive Types based on Urine Chloride; Brief yet high-yield review of compensation and how to make sense of compensation formulas in...
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High-Yield Critical Care & Nephrology: Metabolic Acidosis (1)
Question-based discussion of the proper framework approach metabolic acidosis, serum versus urinary anion gap, categories of high-anion-gap versus normal anion-gap acidosis and are discussed.
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High-Yield Emergency Medicine & Critical Care: Rhabdomyolysis
Question-based Discussion of risk factors, workup and management of rhabdomyolysis.
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High-Yield Disroders of Calcium & Phosphate (Electrolytes, Nephrology, Endocrinology)
Question-based Review on Differential Diagnosis of Hypercalcemia (Pseudohypercalcemia, PTH-dependent vs PTH-independent Hypercalcemia) and Hypocalcemia; Vitamin D abnormalities, Abnormalities of Phosphate. Also discussed: Workup & Management of Humoral Hypercalcemia of Malignancy, Familial...
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High-Yield Electrolytes: Differential Diagnosis & Approach to Hypokalemia and Magnesium Disorders
Question-based review on differential diagnosis and algorithmic approach to workup & management of hypokalemia followed by a discussion of magnesium abnormalities.
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High-Yield Electrolytes: Differential Diagnosis & Approach to Hyperkalemia
Question-based Approach to differential diagnosis and hierarchical management in hyperkalemia.
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High-Yield Electrolyte Abnormalities (1) : Differential Diagnosis of Na Disordders
Differential Diagnosis of pseudohypernatremia, Hypovolemic, Euvolemic and Hypervolemic Hypernatremia as well as Differential Diagnosis of pseudohyponatremia vs true hyponatremia is discussed.
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High-Yield Pediatric Rheumatology (2): Kawasaki Disease & Henoch-Schönlein purpura
A High-yield fully question-based review of childhood vasculitides
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High-Yield Vasculitides (2): Wegener's, Churg Strauss, Buerger's Disease, Polyarteritis Nodosa, Microscopic PAN
The important question is when to suspect vasculitis based on clinical presentation? We discuss differentials and workup (with emphasis on ANCA positivity or negativity or markers of Glomerular involvement) as well as management options and complications (including Mono-neuritis multiplex) for…
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High-Yield Vasculitides (1): Giant-cell versus Takayasu, Differential Diagnosis & General Management of Vasculitides
We discuss the general differential diagnosis & framework of workup for large-vessel, medium-vessel & small-vessel vasculitides, general treatment guidelines and prognostication for vasculitides; Then we focus (in this episode) on large-vessel vasculitides (Giant-cell & Takayasu arthritis)
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High-Yield Rheumatology: Amyloidosis + A quick audience survey
Differential diagnosis and workup of primary versus 2ndary amyloidosis ( including indication for abdominal fat pad versus single-organ biopsy, required workup for plasma-cell dyscrasia in Biopsy-confirmed amyloidosis, Required organ-function tests in Amyloidosis ) as well as management for…
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High-Yield Rheumatology: Seronegative Spondyloarthropathies (2) - Differential Diagnosis & Step-Up Management
In this episode we first finish the discussion of the remaining subtypes of SNSAPs (namely Reactive ARthritis & Entropathic arthropathies / IBD-related Arthropathies) while discussing the important differential diagnosis for each category. We finish with a high-yield subject of approach framework...
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High-Yield Rheumatology: Seronegative Spondyloarthropathies (1)
High-yield question-based review of clinical points regarding subjective, objective, assessment and plan (SOAP) approach to seronegatives; We first discuss the general points relevant to this category of inflammatory arthritides then we initiate an in-depth discussion of each individual disorder...
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High-Yield Surgery: Preoperative Risk Assessment (1)
General approach to preoperative functional assessment using American Society of Anesthesiology Functional & Preoperative Status guidelines , Metabolic Equivalent, Cardiac Risk Assessment of MACE based on risk of patient versus the risks of surgical procedures, Utilizing Revised Cardiac Risk…
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High-Yield Surgery: Surgical Site Complications (SSI, Fascial Disruption, Dehiscence, Evisceration)
We discuss surgical site infection (SSI), Wound disruption and dehiscence, Superficial & deep Fascial Disruption, as well as wound evisceration and ventral hernia.
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High-Yield Pediatric Neurology : Differential Diagnosis & Management Approach to Childhood Seizures with Test-taking Skills (Premium)
Differential Diagnosis & Management Approach of common childhood seizures including some genetic & hereditary subtypes , like benign rollandic, juvenile myoclonic and childhood absence seizure; we finish with a DDxing of childhood hemiplegia. Please make sure you have reviewed our episode on...
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High-Yield Psychiatry: Management of Sleep Disorders (Premium)
While the initial step in managing sleep disorders involves ruling out 2ndary causes, in most cases (including the primary sleep disorders) the first intervention includes sleep hygiene and behavioral modifications; it is crucial to know when CBT-Insomnia is the recommended initial intervention…
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High-Yield Psychiatry: Differential Diagnosis of Sleep Disorders (Premium)
Differential Diagnosis of 7 major DSM-V categories of sleep disorders including Insomnia, Parasomnias (REM-related & Non-REM type), Sleep related breathing disorders, Sleep related movement disorders, Central Hypersomnia (including Narcolepsy), and Circadian-Rhythm Disorders / Sleep-Wake Phase...
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High-Yield Pediatrics: Febrile Seizure (Case-Based Approaches & Differential Diagnosis)
We discuss definition of febrile seizure with required criteria, followed by discussing simple versus complex types as well as their workup and management with an in-depth discussion of how to address family concerns; we then finish with the important differential diagnosis approach between…
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Prenatal Screening
An overview of prenatal screening during pregnancy; we discuss first prenatal visit, overall algorithm of prenatal assessment, types of infectious and non-infectious labs as well as general versus risk-specific panels of prenatal screening as a high-yield framework of prenatal care and follow up.
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High-Yield Reproductive Embryology
Question-Based Review of Reproductive Embryology (only clinically relevant points)
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High-Yiled Allergy & Immunology: Hypersensitivity
In-depth discussion of pathophysiologic mechanisms and examples of four major classes of hypersensitivity reactions; relevant for USMLE step 1 and USMLE step 2,3
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High-Yield Allergy & Immunology: Basic Science Foundation of Immunodeficiencies & Immunosuppression
Basic science foundational knowledge required for understanding the pathogenesis of different primary immunodeficiency syndromes as well as closely-related mechanisms interrupted by immunosuppressive agents;
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High-Yield Rheumatology: Rheumatoid Arthritis versus Osteoarthritis (DJD)
Comparing & Contrasting the Pathogenesis, Clinical features, Patterns of joint involvement, Diagnostic workup and Management options for rheumatoid arthritis versus osteoarthritis (AKA Degenerative Joint Disease); Next episode will provide a more in depth-discussion of rehumatoid arthritis...
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High-Yield Pediatric Orthopedics: Kyphosis, Scoliosis, Low Back Pain (Including Spondylolysis & Spondylolisthesis among others)
A high-yield discussion of clinical assessment and management options for kyphosis, scoliosis, and causes of low back pain in children (including muscle strain, spondylolysis, Discitis and Herniated Disk)
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High-Yield Disruptive Behavior & Impulse-Control Disorders: Oppositional Defiant Disorder, Conduct Disorder, Intermittent Explosive Disorder, Disruptive Mood Dysregulation Disorder
High-Yield Question-Based Review of Impulse control and disruptive behavior disorders with their age considerations Discussion of Differential Diagnosis of Oppositional Defiant Disorder, Conduct Disorder, Intermittent Explosive Disorder, Disruptive mood Dysregulation Disorder, Pyromania, Kleptomania
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High-Yield Child & Adolescent Psychiatry (Neurodevelopmental Disorders): Autism Spectrum Disorder
Discussion of DSM-V diagnostic criteria and the difference with DSM-IV conditions Important developmental features & assessment of developmental milestones A brief list of important Differential Diagnoses of Autism Spectrum Disorder Genetic disorders & Inborn Errors of Metabolism that can be the...
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High-Yield Child & Adolescent Psychiatry: Hyperkinetic Movement Disorders of Childhood (Tics, Tourette, Stereotypies, Rett, Differential list for Chorea, Dystonia and Myoclonus)
A questioned-based review of hyperkinetic movement disorders of childhood with emphasis on Tics (primary and 2ndary) and Tourette syndrome as well as stereotypies (as important differential diagnosis of Autism Spectrum Disorder) including Rett Syndrome (X-linked Dominant developmental regression)...
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Child & Adolescent Psychiatry (Neurodevelopmental Disorders): Clinical Framework and Learning Tips
An introduction to 6 major DSM-V categories of child & adolescent psychiatry A discussion of 4 major clinical complaints among children & adolescent with neurodevelopmental disorders A brief overview of Differential Diagnosis for child behavioral problems, poor school performance, speech problems...
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Frequently Asked Questions
How many episodes does The High-Yield Podcast have?
The High-Yield Podcast currently has 106 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is The High-Yield Podcast about?
An Up-to-date Audio-Flashcards Review of Medicine
How often does The High-Yield Podcast release new episodes?
The High-Yield Podcast publishes regularly with 106 episodes available. Check the episode list for the typical release schedule.
Where can I listen to The High-Yield Podcast?
You can listen to The High-Yield Podcast on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts The High-Yield Podcast?
The High-Yield Podcast is created and hosted by Ardalan Vossoughi, MD.
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