The Lancet Digital Health in conversation with

Can speech reveal the progression of a neurodegenerative disease? In this episode of In Conversation With…, Evgenia Koutsouki, Senior Editor at The Lancet Digital Health, speaks with Professor Anne-Catherine Bachoud-Lévi about her team's latest research on NDSNet, a deep learning model that uses speech recordings to estimate clinical status in people with Huntington's disease. They discuss the growing role of speech-based digital biomarkers in neurology, how AI can help monitor disease progression, and why subtle changes in speech may provide valuable insights into underlying brain changes before they become apparent on conventional clinical assessments. The conversation also explores the challenges of validating AI tools in real-world settings and the future of remote, scalable monitoring for Huntington's disease and other neurodegenerative disorders. Tune in to listen to Professor Bachoud-Lévi’s insights on how speech, digital health technologies, and machine learning are reshaping the way we assess and monitor neurological disease. Click here to read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(26)00048-8/fulltext

Ruben Hemelings and Leo Schmetterer from the Singapore Eye Research Institute join Lucy Dunbar to discuss G-PROG, a deep learning tool that predicts glaucoma progression from fundus photographs. Click here to read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(26)00055-5/fulltext

Dr Shaoxu Wu from Sun Yat-sen Memorial Hospital joins Dr Shangrong Han to discuss PanCAM, an AI pathology model that detects lymph-node metastasis across diverse cancers with robust performance. Click here to read the article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00143-8/fulltext

Dr Shaoxu Wu from Sun Yat-sen Memorial Hospital joins Dr Shangrong Han to discuss PanCAM, an AI pathology model that detects lymph-node metastasis across diverse cancers with robust performance. Click here to read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00143-8/fulltext

Hugo Aerts and Ray Mak from Mass General Brigham join Lucy Dunbar to discuss FaceAge, a deep learning tool that estimates biological age from simple face photographs, and its implications in aiding clinicians in predicting prognoses for people with cancer. Read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(25)00042-1/fulltext?dgcid=buzzsprout_icw_podcast_01-05-25_landig Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Mohamed Omar joins The Lancet Digital Health to discuss pathology and generative AI from a Digital Health Perspective. We explore expert journeys, AI applications in diagnostics, GPT-4's role, integration challenges, ethical considerations, democratisation of knowledge, and future advancements in the field. Read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(24)00114-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_landig Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Developing and validating an algorithm for automated circulatory arrest detection with wrist-derived photoplethysmography with Judith Bonnes from the Department of Cardiology of the Radboud University Medical Center - Netherlands. Read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(23)00249-2/fulltext?dgcid=buzzsprout_icw_podcast_generic_landig Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Dr Andrew Soltan joins Dr Lucy Dunbar to discuss the development, testing and deployment of a federated learning system across four UK hospital groups. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Dr Mamatha Bhat joins Dr Lucy Dunbar to discuss the development of deep learning algorithms in predicting risk of significant fibrosis after liver transplantation. Read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(23)00068-7/fulltext?dgcid=buzzsprout_icw_podcast_general_landig Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Xiao Liu joins Diana Samuel to discuss how to improve the reporting of artificial intelligence-based clinical research studies and the representativeness of health datasets. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Ashleigh Myall joins Diana Samuel to discuss a new machine-learning framework that integrates dynamic patient-contact networks with patient clinical variables and contextual hospital variables to predict hospital-onset COVID-19 infections. Read the full article: Prediction of hospital-onset COVID-19 infections using dynamic networks of patient contact Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Judy Gichoya, Leo Celi and Laleh Seyyed-Kalantari join Rupa Sarkar to discuss how algorithms can predict a patient's race from medical data. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Dr Caroline Figueroa and Dr Rupa Sarkar talk about the social and economic fallout from COVID-19 which has further exacerbated gender inequities and the need for a feminist outlook in digital health.  Read the full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(21)00118-7/fulltext Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Mihaela van der Schaar and Vincent J Gnanapragasam join Diana Samuel to discuss a new machine learning-based prognostic model for prediction of 10-year mortality from non-metastatic prostate cancer. Read full article: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(20)30314-9/fulltext Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Vence Bonham joins Diana Samuel to discuss the impact of genomics and precision medicine on health disparities, and the need for greater diversity in genomic research studies. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Deepti Gurdasani joins Rupa Sarkar to discuss bias and inequalities in health data and artificial intelligence and the impact of COVID-19. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Maimuna S Majumder joins Diana Samuel to discuss how misinformation on COVID-19 can influence the public’s online search interests, and the potential impact this can have on their health. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv

Sara Gerke and Timo Minssen join Diana Samuel to discuss the European Commission’s white paper on artificial intelligence (published in February 2020), and the challenges of implementing the outlined approach in healthcare. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv