The Michael J. Fox Foundation Parkinson's Podcast

Many people diagnosed with Parkinson’s and their loved ones wonder what caused the disease. Researchers believe Parkinson’s is caused by a mix of genetic, environmental and age-related factors that may contribute differently to each person. Tune in to audio from this month’s Third Thursdays Webinar to hear our panel of leading Parkinson’s experts discuss the latest efforts to understand what causes the disease so we can better treat and one day prevent it altogether.Join the movement to end Parkinson’s this Parkinson’s Awareness Month at michaeljfox.org/AprilLike our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Parkinson’s disease (PD) is the world’s fastest-growing neurological disease, affecting millions globally. Yet many misconceptions persist about life with the disease, how to treat it and the research going into the search for better therapies. Tune into this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast to listen to our panel of experts including people living with PD, a researcher and movement disorder specialists debunk common myths about Parkinson’s disease and answer community questions.Discover opportunities to take action and join millions of others moving us closer to a cure. https://www.michaeljfox.org/parkinsons-awareness-monthLike our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Sleep is an important part of physical and mental health, but Parkinson’s symptoms and medication side effects can make a good night’s sleep hard to find. Insomnia, nocturia, medication wearing off, REM sleep behavior disorder (RBD) and more can interrupt sleep. Tune into audio from this month’s Third Thursdays Webinar to hear our panel of experts discuss the latest research on the connection between sleep and Parkinson’s disease (PD) and share practical strategies for setting yourself up for the best rest possible.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

A world without Parkinson’s will only be made possible through the work and energy of the Parkinson’s community — people living with the disease and their loved ones, researchers, clinicians, industry leaders, lawmakers and others. Catalyzing that community towards productive action is one of The Michael J. Fox Foundation’s (MJFF) four main areas of research focus in its Strategic Research Agenda, along with more clearly defining Parkinson’s disease, building better treatment pipelines and speeding clinical trial decision-making.In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, part of its award-winning Parkinson’s Science POV series, Maggie Kuhl, vice president of patient engagement at MJFF, leads a conversation about these efforts with two veteran scientists: Brian Fiske, PhD, chief scientist, MJFF and Mark Frasier, PhD, chief scientist, MJFF.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0There are so many ways to get involved in Parkinson’s community, whether it’s becoming an advocate, joining Team Fox or participating in research. Learn more at michaeljfox.orgThe Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

How can I show up for my partner with Parkinson’s? How can I best support my parent with PD from afar? How can my loved one and I work together to make decisions as symptoms change? Our community has many questions about how to best support a loved one with Parkinson’s disease. Tune in to audio from this month’s Third Thursdays Webinar to hear our panel of experts — including care partners, a person living with PD, a social worker and a psychologist — discuss strategies for effective communication and shared decision-making to keep a partnership strong through Parkinson’s.This webinar received support from Acadia Pharmaceuticals. Learn more at: moretoparkinson’s.comLike our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Diet is a useful tool to feel and live better, whether you live with Parkinson’s or not. But putting healthy eating into practice can be tricky. In audio from this popular Ask the MD video, movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, DipABLM, speaks with Erin Presant, DO, movement disorder and culinary medicine specialist. Together, they answer common questions about how diet can support brain health and help manage disease.Listen now or watch the video. You can also check out our page on lifestyle strategies for living well with Parkinson’s.Rather listen on the go? Subscribe to our Michael J. Fox Foundation Parkinson’s Podcast wherever you get your podcasts.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

How does research into Parkinson’s and Alzheimer’s overlap, and what insights are being revealed? Tune into audio from this month’s Third Thursdays Webinar to hear our panel of experts discuss what scientists are learning about how these diseases affect the brain and how understanding their links may lead to better care for people living with a disease.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

No matter your age, whether you have Parkinson’s or not, there are steps you can take today to boost your brain health. In this extended version of a popular Ask the MD video, movement disorder specialist, life medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, sits down with Ayesha Sherzai, MD, and Dean Sherzai, MD, PhD, known as The Brain Docs. Together they answer community questions and share tips for using lifestyle medicine to help your brain.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Experiencing some stress is a normal part of life, but many people living with Parkinson’s notice stress may worsen symptoms and make medication less effective. And chronic stress can cause lasting impacts to mental and physical health. Tune into audio from this Third Thursday’s Webinar to hear our panel of experts discuss how stress affects the body and how to reduce its harm.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Earlier this year, The Michael J. Fox Foundation hosted its 2025 Research Roundtable, “Building on Breakthroughs.” Tune into audio from this event to hear Parkinson’s experts and MJFF staff discuss the latest in lifestyle medicine and treatments in the pipeline, as well as the power of advocating for Parkinson’s policy.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

What is AI? How do scientists use it? Where does the data come from? Can AI help find a cure for Parkinson’s?  As the use of artificial intelligence, or AI, becomes more widespread, our community has asked us many questions about how scientists may be using the technology to further Parkinson’s research. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, in its award-wining "Parkinson’s Science POV" series, Maggie Kuhl, vice president of patient engagement at MJFF, leads a conversation to answer some of those questions with: Bradford Casey, PhD, senior scientific portfolio manager, MJFF Brian Fiske, PhD, chief scientist, MJFF Mark Frasier, PhD, chief scientist, MJFF Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Parkinson’s research has had a transformative year as researchers have built on breakthroughs to learn more about the disease and how to treat it. Tune into audio from this Third Thursday’s Webinar to hear our panel of experts discuss how Parkinson’s research has advanced in 2025 and what the future could look like.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiRead more about this year in research at https://viewer.joomag.com/2025-year-in-review/0030141001760361264Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

What do you know about gene therapy and its potential for treating Parkinson’s? In this audio from our Third Thursdays Webinar, you’ll learn what exactly gene therapy is and how it works, who gene therapy might work for and the role of genetic testing. You’ll also get a status report on investigations into gene therapy for Parkinson’s. Panelists include experts in the field as well as a person with Parkinson’s and her care partner. Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0  Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.com/podcast-ppmi Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

As Parkinson’s symptoms change over the years, different treatments may be needed to best manage symptoms and side effects. Since last fall, the U.S. Food and Drug Administration has approved five new options for people living with the disease, including two continuous, under-the-skin infusion pumps. Tune into audio from this Third Thursday’s Webinar to hear our panel of experts discuss these options and other strategies to treat progressing Parkinson’s disease.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Stepping back from the workforce is a milestone event in any life, and Parkinson’s disease (PD) adds an emotional and logistical layer. Many people living with the disease think differently about when and how to retire as they balance symptoms, their financial and health needs and their plans and interests. Tune into this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast to listen to our expert panel of a person living with Parkinson’s, a care partner and people who work with the Parkinson’s community discuss retirement and Parkinson’s. They share advice from their own lives and tips for people entering a new phase of their life.  Check out our free employment guide. https://www.michaeljfox.org/news/workplace-challenges  Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

While there have been improvements in therapies to treat Parkinson’s symptoms, people living with the disease and their loved ones await a treatment that will slow the progression of Parkinson’s disease (PD) or stop it entirely. These therapies, called disease-modifying therapies, have the potential to change how PD is treated and experienced. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss disease-modifying therapies and the latest in Parkinson’s research. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi. This webinar was produced with support from Biohaven. https://www.biohavenclinicaltrials.com/clinical-studies/parkinsons-disease/  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

A Parkinson’s disease (PD) diagnosis can impact many areas of life, including how you get work done and think about your career. It can lead to questions like: Should I disclose my diagnosis to my employer and colleagues? How do I adapt my work around my symptoms? What legal protections do I have? Tune into this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast to listen to our expert panel of people living with PD, a care partner, and an employment consultant discuss employment and Parkinson’s. They share their stories and offer the tips they’ve learned along the way. Check out our free employment guide. https://www.michaeljfox.org/news/workplace-challengesLike our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Researchers are investigating many options to treat Parkinson’s disease (PD) with stem cells, including reprogramming them to replace lost dopamine-producing neurons and creating supportive brain cells to keep neurons healthy. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss the latest stem cell research and answer audience questions.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi. This webinar was produced with support from BlueRock Therapeutics.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

How do I tell my children about my Parkinson’s disease (PD) diagnosis? How do I explain a tremor to my grandkids? How can I support my parent with Parkinson’s from a distance? How can my spouse and I communicate around a symptom of apathy? Every year our community submits thousands of questions online and at in-person events. Many are about Parkinson’s symptoms, treatment options and the latest research, but we’re also asked questions about relationships and how to maintain connection with loved ones with Parkinson’s in the picture. In this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast, our expert panel tackles questions on relationships and shares their personal experiences and advice. To connect with others for support and community, join the Parkinson’s Buddy Network. https://parkinsonsbuddynetwork.michaeljfox.org/ Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Technology can offer people living with Parkinson’s disease (PD) much needed support in several areas of life, from apps to keep track of medication timing, wearables to help smooth gait, websites to monitor symptoms and more. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss how tech tools can be incorporated in daily living with PD and how to find your best options. They also share personal tips and experiences and answer audience questions.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Advances in imaging technology offer researchers a window into how Parkinson’s disease affects the brain, which could reshape how the disease is diagnosed and treated. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, in its award-winning Parkinson’s Science POV series, David Kumbroch, senior science writer at MJFF, lead a conversation with: Jamie Eberling, PhD, senior vice present of research resources at MJFF. Roger Gunn, PhD, chief science officer at Xing Imaging. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Learn more about the many ways to get involved today at michaeljfox.orgWhether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Having a network of health care professionals, loved ones and community members as part of a care team has shown to improve the quality of life for those living with Parkinson’s disease (PD) and their loved ones. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss how to make the most of your appointments, find specialists and coordinate care to best support the person living with the disease. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Life with Parkinson’s disease (PD) is shaped by myriad factors, including sexual orientation and gender identity that shape access to care, lifestyle decisions and more. In this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast, our expert panel shares their personal stories and discusses the ongoing research into the health concerns and needs of LGBTQ+ people living with PD. To connect with others for support and community, join the Parkinson’s Buddy Network. https://parkinsonsbuddynetwork.michaeljfox.org/ Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi. Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

The beliefs and perceptions that friends, family, employers and even strangers hold about Parkinson’s disease (PD) shape the experience of living with the disease. Facing misperceptions and stigma can cause isolation and worsen symptoms. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts have a candid and compassionate conversation about times they’ve faced stigma, how they’ve navigated it and how they’re working to change misperceptions of Parkinson’s to improve life for everyone living with the disease.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.    Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

There are so many ways to get involved with Parkinson’s disease, from community building to advocacy, research participation to fundraising. Taking that first step toward involvement can be daunting, but many people say it’s a critical part of living well with the disease. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, members of the Foundation’s Patient Council share stories of their own first steps, explore how engagement has impacted their journeys and offer advice and perspective to others who are looking for ways to make meaningful change. Tune in to hear guest hosts Jimmy Choi, diagnosed with Parkinson’s in 2003, and Hadley Ferguson, diagnosed with multiple system atrophy (MSA-P), an atypical Parkinsonism in 2014, reflect on those stories, recorded live in the MJFF offices.  Learn more about the many ways to get involved today at michaeljfox.org. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Life with Parkinson’s comes with a vast range of emotions, wherever you are in your disease journey. Shock, grief, optimism, fear, denial, hope, humor and more can all be a part of the emotional landscape for people living with the disease and their loved ones. Tune into audio from this special edition Third Thursdays Webinar to listen to our panel of experts have a frank and deep conversation about how they’ve navigated their feelings over the years, how they’ve managed challenging emotions and what lifts them up and brings them hope. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Smell loss can be among the earliest signs of Parkinson’s disease (PD) and other neurodegenerative diseases, signaling changes in the brain years before other symptoms are noticeable. Because of the link between smell and brain health, researchers are very interested in understanding more about how people with smell loss go on to either develop a disease or not, and why some people with PD still are able to smell. To learn more about the latest research, tune into audio from this Third Thursdays Webinar and listen to expert panelists discuss the science of smell and what scientists are learning about its connection to disease. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

You could take any two humans on earth and their genetic code will be roughly 99 percent the same — it’s the small differences in code that lead to different experiences and outcomes, including the risk of developing diseases like Parkinson’s. Scientists are learning more about which genetic changes are linked to Parkinson’s disease, revealing important insights into disease biology and progression. Tune into this episode of our award-winning “Parkinson’s Science POV” series to learn how researchers are using genetics to better understand the disease and work toward better treatments for all.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  This episode was made possible by Prevail Therapeutics. Partner support allows us to furnish high-quality educational content to the Parkinson's community while maintaining our commitment to allocate donor dollars to high-impact research. Editorial control of all Michael J. Fox Foundation-published content rests solely with the Foundation. Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

With three new Parkinson’s treatments approved in the last year, there are more options than ever before for people living with the disease. Tune into audio from this Third Thursdays Webinar to hear movement disorder specialists, research experts and a person living with Parkinson’s answer community questions about the new treatments available, explain how therapies make it through FDA approval and share the latest on treatments in the pipeline.   Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, shares tips on medication management for people at every stage of the disease journey.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

If depression, anxiety or apathy occur as part of a Parkinson’s journey, it can be easy to feel alone, isolated or unsure of what might bring relief. But there are ways to manage these symptoms. Tune into audio from this Third Thursdays Webinar to hear people living with Parkinson’s share their stories of coping with mood changes as well as a movement disorder specialist and psychiatrist discuss pharmacological and non-pharmacological treatments options. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, answers community questions on Parkinson’s and exercise with physical therapist and rehab scientist Cristina Colón-Semenza, PhD. Listen to the audio or watch the video. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Being a care partner to someone with Parkinson’s disease (PD) can be a shifting and complex role, as symptoms and life circumstances change. And sometimes, this can lead to stress and even burnout for the care partner. Tune into audio from this Third Thursdays Webinar to hear expert panelists discuss how to navigate care partnership, including everyday strategies to de-stress and find supportive community.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

It is widely known that a healthy diet can provide essential nutrients and lead to a multitude of benefits, but growing evidence has highlighted important links between diet, nutrition, and brain health, particularly related to neurodegenerative disease. In this episode, Dr. Puja Agarwal discusses her research investigating the role that diet and nutrition may play in Parkinson’s disease and other neurodegenerative conditions. Evidence from her studies and the work of others suggests that certain diets, including the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, are associated with brain health and may have the potential to delay the onset or slow progression of Parkinson's disease or other neurodegenerative conditions. We hear more about her ongoing MJFF-funded research project examining the role of diet in the progression of parkinsonian signs and its association with Lewy body pathologies, as well as future directions for this exciting line of research. Puja is an Assistant Professor in the Department of Internal Medicine at Rush University.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstartedThis podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Parkinson's disease significantly impacts various aspects of communication, and this can make it challenging for people with the disease to communicate effectively, be understood by others, and engage in social situations. Dr. Gemma Moya-Galé joins this episode to talk about her work on voice and communication in people with Parkinson’s disease. In particular, she discusses a novel app she and her team are developing, with funding from The Michael J. Fox Foundation, to help people with Parkinson’s improve how well their speech is understood. The app uses evidence-based principles from speech therapy and noise-augmented automatic speech recognition to provide speech training and feedback. She also shares her recent research on linguistically and culturally responsive methods for addressing communication challenges in both English- and Spanish-speaking individuals with Parkinson's disease, and how this approach has the potential to improve clinical care. Gemma is an Assistant Professor of Communication Sciences and Disorders, as well as the Director of the Communication, Technology, and Language Diversity Lab at Teachers College, Columbia University.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstartedThis podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Understanding the biology of Parkinson’s disease (PD) and turning that knowledge into better treatments is a complex undertaking. In this episode of the award-winning Parkinson’s Science POV series, scientists at The Michael J. Fox Foundation (MJFF) discuss how they are tackling this problem from every angle. Whether it’s using cutting-edge imaging to get a picture of the disease in the brain or working with the community to develop better options to treat walking difficulties, our researchers are collaborating to discover the next wave of treatment options and close in on a cure. Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 Watch our webinar or read our Year in Review at michaeljfox.org.The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Certain populations are disproportionately affected by neurological diseases, including Parkinson's and other neurodegenerative diseases. A lot of work remains to be done to improve brain health outcomes and promote healthy brain aging across the lifespan, particularly for minoritized, underrepresented populations. Including participants from diverse backgrounds in research helps ensure that the results from studies and clinical trials in the field are valid, generalizable, and representative of all individuals affected by these diseases. In this episode, Dr. Monica Rivera-Mindt discusses brain health inequities in neurodegenerative diseases, her work using culturally informed community-engaged research methods to improve representation in research studies, important gaps in the literature, lessons learned from the Alzheimer's Disease Neuroimaging Initiative (ADNI) Diversity Task Force that could be applied in Parkinson's disease research, and more. Monica is Professor of Psychology, Latinx studies, and African and African American studies at Fordham University, and she has a joint appointment as Professor of Neurology at the Icahn School of Medicine at Mount Sinai. She is also a board-certified neuropsychologist.Mentioned in this episode:This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

With two new drugs approved by the FDA, a National Plan signed into law and many advances in our understanding of Parkinson’s disease, 2024 has been a transformative year in Parkinson’s research. Tune into audio from this month’s Third Thursdays Webinar to hear research experts from industry and academia talk with MJFF staff about the latest research on disease biology and emerging therapies.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0   The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Alpha-synuclein plays a key role in the pathophysiology of Parkinson's disease, and researchers have been investigating this protein as a therapeutic target and also as a potential biomarker for the disease. The alpha-synuclein seed amplification assay, developed by Dr. Claudio Soto and colleagues, leverages the self-replicating nature of the misfolded alpha-synuclein proteins that form aggregates in Parkinson's disease. Amplifying misfolded alpha-synuclein can allow researchers and clinicians to detect the presence of the pathological form of the protein in biospecimens, even when the amount of misfolded alpha-synuclein in a sample is very low. In this episode, Claudio discusses his work in this area and how it has opened the doors for a variety of potential uses of the alpha-synuclein seed amplification assay, including applications in diagnosis, clinical trials, and drug development for Parkinson's disease.This year, Claudio received the 2024 Robert A. Pritzker Prize for Leadership in Parkinson’s Research for his substantial contributions to research and his commitment to mentoring the next generation of scientists in the field. Claudio is the Huffington’s Distinguished University Chair, Professor of Neurology, and Director of the George and Cynthia Mitchell Center for Alzheimer’s Disease and Related Brain Disorders at The University of Texas Medical School in Houston. He is also the Founder, Vice-President, and Chief Scientific Officer at AMPRION Inc.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstartedThis podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Each person living with Parkinson’s disease (PD) will have a unique journey with their treatments, including the decision to have deep brain stimulation (DBS), which is a surgical procedure to treat Parkinson’s motor symptoms. While DBS isn’t suitable for everyone, it can be helpful in the right person, and it’s a complex, lifelong choice. And although the experience goes far beyond surgery day, brain surgery often looms large in people’s minds as they are contemplating DBS. In this episode, our expert panelists tackle community-sourced questions on DBS surgery day: what to wear, how loved ones can support, what it feels like to be awake during brain surgery and more. Tune in to hear from two people who have had DBS, a neurosurgeon and a movement disorder specialist and learn more about the realities of surgery day.  For more information on deep brain stimulation, download our newly updated, comprehensive guide or check out our webinar at michaeljfox.org.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community: https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. People from all backgrounds with and without Parkinson’s can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

To help meet the growing global need for more movement disorders specialists, The Michael J. Fox Foundation created the Edmond J. Safra Fellowship in Movement Disorders in collaboration with longtime partner the Edmond J. Safra Foundation. This program supports the training of movement disorders specialists who will provide expert care and drive advances in Parkinson's research. The program is positively impacting early-career clinician-researchers, as well as the centers where they train. These impacts will continue to grow over the years as more fellows are trained. In this episode, Dr. Marcelo Merello and Dr. Sergio Castillo-Torres share their insights and perspectives as a Fellowship Director and a Fellow in the program, respectively. Marcelo is Director of the Department of Neurosciences and Chief of the Movement Disorders Clinic at the Institute for Neurological Research or Fleni Hospital. He is fellowship Director at Fleni and the University of Buenos Aires. In addition, Marcelo is Principal Investigator with the National Council for Scientific and Technical Research and Professor of Neurodegenerative Diseases at the Pontifical Catholic University of Argentina. Sergio is an Associate Professor in Neurology and Internal Medicine at the Dr. Jose E. Gonzales University Hospital of the Autonomous University of Nuevo Leon. He was an Edmond J. Safra Fellow in Movement Disorders at Fleni Hospital. Visit michaeljfox.org/fellowship to learn more about the Edmond J. Safra Fellowship in Movement Disorders.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstartedThis podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Troubles with gait – slow walking, shuffling steps and foot dragging and more – can be symptoms of Parkinson’s. In audio from this Third Thursdays Webinar, our experts explore the robust research efforts underway to understand and treat gait issues, from physical rehab interventions to deep brain stimulation modifications to wearable robots designed to smooth gait.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0  The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.  Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Stem cell models derived from patients with Parkinson’s disease are valuable tools that are helping researchers around the world to better understand the underlying causes of neurodegeneration and to develop biomarkers and new therapies. To maximize the potential impacts of these tools, it is critical that they are developed and shared according to the principles of open science. In her interview, Dr. Birgitt Schüle discusses her work developing alpha-synuclein cell lines, challenges and opportunities in the field, and important considerations surrounding open science. She goes in-depth on how the cell lines were developed, characterized, and deposited with the American Tissue and Cell Collection (ATCC) with funding support from The Michael J. Fox Foundation, as well as how these cells can be used to fuel future discoveries. Birgitt is an Associate Professor in the Department of Pathology at Stanford University School of Medicine and Co-Director of the Alzheimer’s Disease Research Center, Neuropathology, and Induced Pluripotent Stem Cell (iPSC) Core. Mentioned in this episode:This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

In this podcast, four people from different backgrounds have a candid conversation on race, stigma and Parkinson’s. They share their experiences trying to find culturally competent medical professionals, overcoming the barriers to research participation, and communicating with their communities about their diagnosis. And they offer tips and advice on finding empowerment through education and advocacy.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community: https://apple.co/3p02Jw0  The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. People from all backgrounds with and without Parkinson's can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi. Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

New qualitative and quantitative tools are being developed to measure and track changes in proteins relevant for neurodegenerative disease, and these tools have the potential to accelerate drug discovery and clinical trials. In this episode, Dr. Judith Steen discusses her work creating novel qualitative and quantitative tools and workflows at the interface of proteomics and transcriptomics, including their novel FLEXI platform. This platform uses targeted, high- throughput quantitative mass spectrometry to isolate, quantify, and identify molecular changes in proteins. She describes her ongoing project, funded by The Michael J. Fox Foundation, to develop FLEXISyn, which aims to track post-translational changes in alpha-synuclein to better understand how the protein becomes dysfunctional and begins misfolding and forming toxic aggregations in Parkinson's disease. Judith is Associate Professor of Neurology at Harvard Medical School, a member of the Harvard Stem Cell Institute, and Director of the Neuroproteomics Laboratory in the F.M. Kirby Neurobiology Center at Boston Children's Hospital.Mentioned in this episode:This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Parkinson’s disease brings with it many potential symptoms, including hallucinations (seeing things that are not there) and delusions (believing things that are not true). Not everyone will experience these symptoms and not everyone who does will find them bothersome, but it can be a source of uncertainty and concern for people living with the disease. In audio from this Third Thursdays Webinar, our expert panel discusses navigating life with these symptoms and medication and non-medication strategies to manage them.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi. Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Substantial research has focused on identifying biomarkers for the diagnosis of Parkinson's disease (PD) as well as monitoring progression of the disease. In developing these biomarkers, it is critical for scientists to consider how the biomarkers will ultimately be used in the clinic and in clinical trials research. In this interview, Dr. Charles (Chuck) Adler shares his perspectives on how biomarkers are currently being used in clinical and research contexts, and what it would take for him to use them more often in clinical practice. He also discusses how groundbreaking collaborative research studies, including the Arizona Study of Aging and Neurodegenerative Disorders and the Parkinson's Progression Markers Initiative (PPMI), are having major impacts on the field. Chuck is Consultant and Professor of Neurology in the Department of Neurology and The Wayne and Kathryn Preisel Professor of Neuroscience Research at the Mayo Clinic Alix School of Medicine at the Mayo Clinic in Arizona.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstartedThis podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Sleep disturbances, such as insomnia, sleep fragmentation, excessive daytime sleepiness, and REM sleep behavior disorder are common in people with Parkinson's disease (PD). Poor sleep quality can also impact other domains of function, including motor function. Prior research has shown that a type of photoreceptor cell in the retina, called melanopsin cells, provide the main light signals to the brain to initiate sleep, and function of these cells is impaired in PD. Dr. Beatix Feigl and her colleagues developed a novel light therapy intervention that selectively activates the melanopsin photoreceptor cells, and in this episode, she discusses the results of a recent randomized controlled trial evaluating the efficacy of this melanopsin photoreceptor-directed light therapy on sleep and circadian rhythm, as well as motor behaviors. She also discusses her earlier work on melanopsin cells that led to the development of standard measures to assess their function. Beatrix is an Ophthalmologist and an Associate Professor in the School of Biomedical Sciences and Center for Vision and Eye Research, as well as the Faculty of Health, at the Queensland University of Technology.Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstartedThis podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Finding the right Parkinson’s treatment plan can be a trial-and-error process. The kind of medication, the dosage, the timing and lifestyle factors are all important pieces of the puzzle. In audio from this Third Thursdays Webinar, our expert panel made up of people living with Parkinson’s disease (PD), a movement disorder specialist and a researcher discuss different medication options, practical tips for finding what works best for you and the latest research on emerging treatments.  Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0 The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi. Mentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Though existing evidence supports that dysfunction in the clearing of cellular debris plays an important role in the development of Parkinson's disease, many unanswered questions remain regarding the mechanisms of the autophagy-lysosomal pathway involved in this process. In particular, research in the field has been limited by a lack of reliable, quantitative tests for monitoring autophagy-lysosome activity. In this interview, Dr. Zhenyu Yue describes his research investigating the cellular and molecular mechanisms for Parkinson's disease and other neurodegenerative diseases, focusing on their work examining the regulation of the autophagy-lysosomal pathway, potential therapeutic targets, and MJFF-funded research that aims to develop sensitive, robust autophagy-lysosome assays to facilitate the discovery of biomarkers for PD using stem cell-derived neurons and biofluids. Zhenyu is the Aidekman Research Professor in the Department of Neurology and Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai. He is also the Director of the Center of Parkinson’s Disease Neurobiology and Director of Basic Research of Movement Disorders at Mount Sinai.Mentioned in this episode:This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience.  These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It’s free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted