PODCAST · health
The Mind-Gut Conversation Podcast
by Emeran Mayer, MD
The Mind-Gut Conversation brings in experts within various fields of health & science to have a discussion with world-renowned gastroenterologist, neuroscientist and bestselling author of The Mind Gut Connection, Emeran Mayer, MD.
Episodes
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What Nutrition Scientists Actually Agree On with Christopher Gardner, PhD | MGC Ep. 127
Nutrition advice seems to change every week, but Dr. Christopher Gardner says the core of what we know has barely moved in fifty years. In this episode of The Mind-Gut Conversation, Dr. Mayer talks with Gardner, a professor of medicine at Stanford University, about his new book, Food Sense.…
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Healthspan vs. Lifespan: What It Takes to Stay Healthy Longer with Dr. Jamie Justice | MGC Ep. 126
Over the past century, average lifespan in Western countries has grown by about 30 years. The years we spend in good health have not kept pace. In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Dr. Jamie Justice, Executive Vice President of the Health Domain at the XPRIZE...
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What Is The Mayer Model? with Emeran Mayer, MD | MGC Ep. 125
After 45 years of research on how the brain and the gut communicate, the question Dr. Emeran Mayer hears most often is not about mechanisms or studies. It is much simpler than that. People tell him they understand the science, they just do not know how to live it. In this episode of The Mind-Gut...
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Why Are We Living Longer But Not Healthier? with Emeran Mayer, MD | MGC Ep. 124
Modern medicine has never been better at keeping people alive. So why are we spending more of our lives unwell? In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer examines a new analysis from the Global Burden of Disease project, published in Lancet Public Health, comparing how long...
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Psychedelics for IBS: Inside the First Clinical Trial with Erin Mauney, MD
For most of the last forty years, irritable bowel syndrome was treated as a problem of the gut alone. The idea that the brain plays a central role took decades to gain acceptance, and it remains contested today. In this episode of The Mind-Gut Conversation, Dr. Mayer is joined by Dr. Erin Mauney…
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Does Your Daily Probiotic Actually Work, or Is It Just Hype? with Kiran Krishnan, PhD | MGC Ep. 122
Millions of people take a daily probiotic without ever asking a basic question: does any of it survive long enough to do anything? In this episode of The Mind-Gut Conversation, Dr. Mayer is joined by Kiran Krishnan, a research microbiologist and Chief Scientific Officer at Microbiome Labs who has...
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What We Get Wrong About Menopause: Hormones & The Gut Microbiome with Emeran Mayer, MD | MGC Ep. 121
Menopause isn't just hot flashes — it's brain fog, bone loss, sleep, mood, and your gut. In this solo episode of The Mind-Gut Conversation, Dr. Emeran Mayer unpacks the ~34 symptoms of perimenopause and menopause, the 2002 hormone-therapy scare that still shapes care today, and what current…
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Is Soil Health the Missing Piece of Human Health? with Sadhguru | MGC Ep. 120
This episode is brought to you by Mayer Nutrition. Use code MINDGUT at checkout to save 10% on your first order of our polyphenol blend, Synaptic Bloom, at https://www.mayernutrition.com. The health of our soil and the health of our gut may be expressions of the same crisis — and healing one may...
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What Science Gets Wrong About Intelligence with Sadhguru | MGC Ep. 119
Neuroscience is built on an assumption most scientists never examine: that the brain is the seat of consciousness, intelligence, and everything that makes us human. Sadhguru thinks that’s like a child staring at a phone while a sunset unfolds right in front of them. In this episode of The…
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What Overwork Actually Does To Your Body with Dr. Emeran Mayer | MGC Ep. 118
Most of us know overwork isn't good for us. But the research on just how damaging it can be, and how quietly the damage accumulates, is more sobering than most people realize. In this episode of The Mind–Gut Conversation, Dr. Emeran Mayer reflects on his own experience of sustained overwork...
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What if Consciousness Starts in Your Gut, Not Your Brain? with Michael Pollan | MGC Ep. 117
Consciousness is one of science's deepest mysteries — and it may be under threat. In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Michael Pollan, author and one of our most important thinkers on the relationship between humans and the natural world, to discuss consciousness,...
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What 99% of Fiber Supplements Get Wrong with Jens Walter, PhD | MGC Ep. 116
For decades, fiber was shorthand for digestiveregularity. Today, the science tells a more complex and far more interesting story. In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Professor Jens Walter, a leading microbiome scientist at University College Cork in Ireland, to...
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Joint Health, Mobility, and the Mind-Body Connection with Jeff Bailey | MGC Ep. 115
Joint pain and limited mobility are often treated as inevitable parts of aging — but what if there's a fundamentally different way to think about joint health? In this episode of The Mind–Gut Conversation, Dr. Mayer sits down with Jeff Bailey, founder of Avita Yoga and author of the bestselling...
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The Truth About Peptides with Dr. Emeran Mayer | MGC Ep. 114
Peptides are everywhere right now — on social media, in wellness clinics, and in the claims of biohackers promising faster healing, sharper thinking, and slower aging. But how much of this is science, and how much is hype? In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer draws on...
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How To Actually Feed Your Gut Microbiome with Anu Simh | MGC Ep. 113
Eating for your microbiome doesn't have to be complicated — but it does require rethinking how we approach food, carbohydrates, and flavor. In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Anu Simh, a board-certified functional health coach, microbiome educator, and author of...
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The Truth About Fiber And Your Gut Health with Matt Amicucci, PhD | MGC Ep. 112
Fiber has been talked about for decades — but emerging research suggests most of us still don't understand what it actually does, how much we need, or why the modern diet has left us so dramatically short of it. In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Dr. Matt…
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Chronic Pain, Brain Health, and the Power of Self Help with Jared Katz | MGC Ep. 111
Chronic pain is often treated as a problem to suppress with medication or surgery, but what if it’s actually a signal from a complex system that needs to be addressed holistically? In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Jared E. Katz, author of Retrain the Brain:...
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How The Gut Microbiome Influences Estrogen After Menopause with David Meriwether, PhD | MGC Ep. 110
Menopause is often described as a simple decline in estrogen production, but emerging microbiome research suggests the story is far more complex. In this episode of The Mind–Gut Conversation, Dr. Mayer is joined by Dr. David Meriwether, a scientist at UCLA’s Goodman Luskin Microbiome Center, to...
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What a 34,000-Person Study Reveals About a "Healthy" Gut with Tim Spector, MD | MGC Ep. 109
In this episode of The Mind–Gut Conversation, Dr. Emeran Mayer sits down with Tim Spector, MD, to discuss the implications of a landmark gut microbiome study involving more than 34,000 participants — one of the largest and most comprehensive efforts to date to understand what a “healthy” gut...
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Why Modern Life is Keeping Our Immune System Switched On with Will Bulsiewicz, MD | MGC Ep. 108
In this episode of The Mind–Gut Conversation, Dr. Emeran Mayer sits down with Will Bulsiewicz, board-certified gastroenterologist, New York Times bestselling author, and one of today’s leading voices in microbiome science. Drawing from his newest book, Plant-Powered Plus, Dr. Bulsiewicz explores...
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What Modern Medicine Gets Wrong About Gut Health with Lauren DeDecker, MD | MGC Ep. 107
In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer sits down with Dr. Lauren DeDecker, a board-certified internal medicine physician with training in nutrition and integrative medicine, to explain how gut health is approached in real-world primary care. They discuss why fiber and…
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A Life Fueled by Passion: Cooking, Culture, and Longevity with Wolfgang Puck | MGC Ep. 106
In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer sits down with Wolfgang Puck, one of the most iconic chefs of our time, for an intimate conversation about the life experiences, creative influences, and personal philosophy that shaped his extraordinary career. Puck reflects on his...
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The Truth About Low FODMAP, SIBO, Gluten & Bloating with Kate Scarlata, RDN | MGC Ep. 105
In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer sits down with Kate Scarlata, RDN, an internationally recognized dietitian, bestselling author, and leading authority on dietary therapies for IBS and chronic digestive disorders. Drawing from her personal medical journey and decades…
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Career Shifts, Authenticity, and Intentional Living with Taylor Bell | MGC Ep. 104
Dr. Emeran Mayer sits down with Taylor Bell, an Ivy League–educated former management consultant turned full-time YouTuber, for a candid conversation on authenticity, ambition, and the health consequences of living out of alignment with your true values. Through her story of leaving a…
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Building Mental Fitness & Healing The Modern Brain with Drew Ramsey, MD | MGC Ep. 103
Dr. Emeran Mayer sits down with Dr. Drew Ramsey, psychiatrist, author, and pioneer in nutritional psychiatry, for a thought-provoking conversation on how we can proactively strengthen and protect our mental health. Drawing from his new book, Healing the Modern Brain: Nine Tenets to Build Mental...
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Healing Trauma and Unlocking Human Potential with Peter Crone | MGC Ep. 102
Dr. Emeran Mayer welcomes Peter Crone, widely known as The Mind Architect, for a profound conversation on healing trauma, dissolving limiting subconscious beliefs, and unlocking human potential. Peter shares how early life experiences shape the subconscious mind, often creating patterns of fear,...
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Menopause, Hormones, and Women’s Health with Dr. Suzanne Gilberg-Lenz | MGC Ep. 101
Dr. Emeran Mayer welcomes Dr. Suzanne Gilberg-Lenz, physician, author, and women’s health advocate, for an in-depth discussion on menopause, hormone therapy, and the integration of holistic practices into modern medicine. Dr. Gilberg shares her path into women’s health, including the creation of...
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How Food Influences Our Mood and Mental Health with Felice Jacka, OAM | MGC Ep. 100
Dr. Emeran Mayer welcomes Professor Felice Jacka, founder of the Food & Mood Centre and a global leader in nutritional psychiatry, for an in-depth discussion on how diet influences mental health and brain function. Felice shares the groundbreaking research that launched an entire field, from the...
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The Mitochondrial Key to Longevity, Stress, & Holistic Health with Martin Picard, PhD | MGC Ep. 99
Dr. Emeran Mayer welcomes Martin Picard, PhD, mitochondrial biologist and systems thinker, for a fascinating conversation on the hidden role of mitochondria in health, stress, and consciousness. Martin explains how mitochondria, far beyond being simple “powerhouses of the cell”, are dynamic...
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The Secrets Behind the World's Longest Living People with Dan Buettner | MGC Ep. 98
Dr. Emeran Mayer welcomes Dan Buettner, National Geographic explorer, Emmy award-winning filmmaker, and founder of the Blue Zones, for an illuminating conversation on the secrets of longevity. Dan explains why people in Blue Zone communities, like Ikaria, Greece, and Nicoya, Costa Rica, live...
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Understanding Sex Differences in Stress and Gut Health | MGC Ep. 97
Dr. Mayer unpacks groundbreaking research on how men and women differ in their responses to stress, emotional stimuli, and gut sensations. Drawing from studies at UCLA’s Oppenheimer Center, the conversation highlights key differences in brain-gut communication, revealing how neural pathways...
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The SIBO Myth: What Clinicians & Patients Should Know | MGC Ep. 96
SIBO—Small Intestinal Bacterial Overgrowth—has become a buzzword in the gut health space, often blamed for symptoms like bloating, gas, and fatigue. But how much of the hype is supported by solid science? In this episode of The Mind-Gut Conversation, Dr. Mayer critically examines the growing SIBO...
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How to Master Stress, Build Lasting Resilience & Slow Aging with Stephen Sideroff, PhD | MGC Ep. 95
In this episode of The Mind-Gut Conversation, I’m thrilled to sit down with Dr. Stephen Sideroff, an internationally recognized psychologist, professor at the UCLA Geffen School of Medicine, and expert in resilience and peak performance. Stephen’s groundbreaking new book, The 9 Pillars of...
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Making America Healthy Again: It Starts with Our Kids with Nora LaTorre | MGC Ep. 94
How do we reverse the chronic disease epidemic affecting millions of children in the United States? According to Nora LaTorre, it starts with fixing what’s on their lunch tray. As CEO of Eat Real, Nora leads a nonprofit tackling the root causes of poor nutrition through a science-backed, K–12...
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What You Can Learn From A Stool Microbiome Test with Cheryl Sew Hoy | MGC Ep. 93
Can a simple stool test help uncover the root causes of gut issues — and guide you toward better long-term health? That’s the bold promise behind Tiny Health, the microbiome testing company founded by Cheryl Sew Hoy. In this episode of The Mind-Gut Conversation, Dr. Emeran Mayer sits down with...
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How To Keep Your Brain Fit Into Older Age with Emeran Mayer, MD | MGC Ep. 92
What do alcohol, sleep, diet and “purpose in life” have in common? According to a powerful new study, they’re all modifiable risk factors that may determine your future risk of stroke, dementia and late-life depression — three of the most pressing health challenges of our time. In this episode of...
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The Exciting Future of Probiotics in Treating Chronic Disease with Deanna Gibson, PhD | MGC Ep. 91
Inflammatory bowel diseases like ulcerative colitis remain among the most difficult chronic conditions to manage — but new science at the intersection of microbiome research and biotechnology may offer hope. In this episode of The Mind-Gut Conversation, I sit down with Dr. Deanna Gibson…
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IBS & The Brain-Gut Connection with Emeran Mayer, MD & Dylan Mayer, MS | MGC Ep. 90
Despite how common IBS is, it remains one of the most misunderstood and misdiagnosed conditions affecting the gut. Whether you’ve been diagnosed with IBS, suspect you might have it or are just curious about the brain-gut connection, this episode is for you. In this episode of The Mind-Gut...
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The Current Science Behind Probiotics with Zain Kassam, MD, MPH | MGC Ep. 89
Are probiotics really the key to unlocking better gut health? Or are they just another overhyped wellness trend? These are some of the most common questions I get after giving a talk or meeting with a patient. In this episode of The Mind-Gut Conversation, I sit downwith Dr. Zain Kassam, Chief...
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Things You Need To Know For Better Gut Health with Emeran Mayer, MD & Dylan Mayer, MS | MGC Ep. 88
Got questions about gut health, diet and the microbiome? In this special Ask Me Anything (AMA) episode of The Mind-Gut Conversation, I answer real questions from our members—covering everything from ADHD and the gut to colonic hydrotherapy, ultra-processed foods and how to fix your microbiome…
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The Truth About Sugar & How it Affects Our Health with Robert Lustig, MD | MGC Ep. 87
Is sugar really the villain behind the chronic disease epidemic? If you care about your metabolic health, obesity and the hidden dangers of processed food, this episode of The Mind-Gut Conversation is one you can’t miss. My guest is Dr. Robert Lustig, an internationally renowned expert on the…
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Psychedelics & Women's Health with Stephanie Karzon, MS | MGC Ep. 86
If you’re curious about the future of women’s health, mental well-being and the role of psychedelics, this episode of The Mind-Gut Conversation is a must-listen! My guest is Stephanie Karzon, a clinical neuropharmacologist, who is at the forefront of psychedelic-assisted therapy and its potential...
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Is Your Food Making You Sick? The Science of Soil and Gut Health with Joel Salatin | MGC Ep. 85
In this must-listen episode of The Mind Gut Conversation, I sit down with regenerative organic farming icon, Joel Salatin, to expose the hidden flaws of industrial agriculture and its impact on our health and the environment. We dive into how soil and gut microbes are deeply connected, why…
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Unpopular Opinions as a Gastroenterologist with Emeran Mayer, MD | MGC Ep. 84
In this special episode of the Mind-Gut Conversation podcast, I discuss my personal opinions on topics related to Small Intestinal Bacterial Overgrowth (SIBO) & Irritable Bowel Syndrome (IBS). Some key questions and topics I discuss are: · The issue with diagnosing SIBO · How to treat SIBO…
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Preventing Alzheimer’s Through Food with Annie Fenn, MD | MGC Ep. 83
Dr. Annie Fenn is the founder of the Brain Health Kitchen, the only cooking school of its kind focused exclusively on brain health and helping people prevent cognitive decline and chronic brain disorders through food and lifestyle. She is a board-certified OB-GYN, who after 20 years of treating...
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The Role of Inflammation in Mental Disorders with Andrew H. Miller, MD | MGC Ep. 82
Welcome back to another episode of the Mind Gut Conversation. Today’s guest is Andrew H. Miller, MD. Dr. Miller is an internationally recognized expert in interactions between the brain and immune system as they relate to depression and has conducted the first clinical trial examining the…
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The Importance of Farm to Table with Norbert Niederkofler | MGC Ep. 81
In this episode of the Mind Gut Conversation, I sit down in person with Norbert Niederkofler, an internationally renowned leader in local sustainable gourmet cuisine, as he explains his unconventional career decisions and his philosophy of letting nature and his local ecosystem determine his...
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The Human Body Was Not Designed For Illness with Patrick Flynn, DC | MGC Ep. 80
In this episode of The Mind Gut Conversation, I sit down with Patrick Flynn, DC as he shares his bold belief that the human body was not designed for illness and, when properly cared for, has the innate ability to heal itself-a perspective that challenges conventional medical norms. Dr. Flynn is…
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Microbiome, Personalized Nutrition and Longevity with Tim Spector, MD | MGC Ep. 79
In this episode of the Mind Gut Conversation podcast, I sit down with Dr. Tim Spector, an internationally renowned expert in microbiome science and personalized nutrition, as well as an acclaimed author. He is a professor of genetic epidemiology at King’s College London and honorary consultant...
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The Science Behind Healthy Aging with Eric Verdin, MD | MGC Ep. 78
In this episode of the Mind Gut Conversation podcast, I speak with Dr. Eric Verdin, one of the world’s experts on healthy aging and longevity. Dr. Verdin is president and CEO of the Buck Institute for Research of Aging, the world’s only research institution singularly focused on the biology of...
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