PODCAST · health
The Peps Report
by MyPeps
Mark and Amy break down the week's peptide research news in plain English: new trials, FDA and WADA decisions, safety alerts, and what the evidence actually shows, including when it doesn't. Every story is sourced, and every episode links to the full write-up on mypeps.info. Mark and Amy are AI-generated voices; every episode is reviewed by our editor, Ryan E., MS. Educational information, not medical advice.
Episodes
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Cagrilintide: the amylin peps that pairs with semaglutide
Mark and Amy look at cagrilintide, a long-acting version of the fullness hormone amylin, developed mainly to pair with semaglutide as CagriSema. They go through what the phase 2 and phase 3 trials found, how it differs from GLP-1 drugs, and where it stands with regulators. The site rates the...
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KPV and the Gut: What Cell and Mouse Studies Show So Far
This week Mark and Amy dig into KPV, a tiny fragment of the hormone α-MSH, and the lab research on its anti-inflammatory effects in gut cells and mice. They also look at two new 2026 lab papers, how to weigh personal reports, and why "not FDA-approved" is not a verdict either way. What we covered...
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GLOW: A Three-Peptide Blend With No Studies of Its Own
GLOW is a premixed vial of BPC-157, TB-500 and GHK-Cu, 70 mg in total, marketed for skin and recovery together. Mark and Amy look at what is actually known. No study has tested the blend itself, so the case for it is borrowed from each ingredient's separate evidence. What we covered What GLOW is…
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Recent discoveries in MOTS-c benefits
Mark and Amy walk through the latest MOTS-c research: a mitochondria-derived peptide studied for insulin sensitivity, exercise capacity, heart damage from sepsis, egg-cell energy in aging, and tissue transplants. They keep one point front and center: most of it is still animal and lab work, and...
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How to store peptides: freezer, fridge and shelf life explained
Mark and Amy break down peptide storage: why freeze-dried powder is the stable form, what oxygen, moisture and light do to a chain of amino acids, and how quickly shelf life drops once water is added. They also cover the 28-day sterility rule, sprays, and why approved drugs like Mounjaro and...
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16 new compounds at Amino Club: what each one is and what the research shows
Mark and Amy dig into the 16 research compounds Amino Club just added, from sermorelin and VIP to the Russian "bioregulator" peptides and designer nasal sprays. They sort which have real human data, which rest on one lab, and what the lab certificates do and don't tell you. Read the full post: 16...
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What Reddit users report on retatrutide, and what the trials actually show
Mark and Amy dig into a new JAMA Network Open study that used AI to sort nearly 150,000 Reddit posts about unapproved retatrutide. Users report hunger, fatigue and a racing heart; the TRIUMPH trials found mostly stomach effects. They walk through where the two pictures match, why they differ, how...
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BPC-157 in 2026: what the evidence actually shows
Mark and Amy dig into BPC-157, maybe the most talked-about peptide online. There are well over a hundred studies behind it, so why can't you get it at a pharmacy? They walk through the animal research, the five small human reports the FDA found, what's still unknown about safety, the WADA ban…
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Semax and Selank explained: Russia's nasal peptides
Mark and Amy dig into Semax and Selank, two short peptides developed in Russia and usually given as nasal drops. They're registered medicines there, but not approved in the US, Europe, the UK or Australia. What does the research actually show, in rats and in people? Where does the FDA's July 2026...
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Peptides for sex and hormones: what a new urology review says the evidence supports
Mark and Amy dig into a new review of peptides used in urology and sexual medicine. Out of 76 studies, only two peptides, PT-141 and tesamorelin, have defined dosing and an approved use, and both approvals are narrow. They also look at why raising IGF-1 isn't the same as a proven benefit, where...
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Gray-market peptides and fentanyl precursors: what the new TRM Labs report found
Mark and Amy dig into a new TRM Labs report: about three in four Chinese chemical vendors it tracked list both peptides and fentanyl precursors, and US buyers send most of the traceable money. They cover what the report can and can't show, the two peptides it named, and what the FDA says about...
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GLP-1 drugs, peptides and surgery: why anaesthetists want to know
Australia's anesthesia college says people on GLP-1 injections or other weight-loss peptides should tell their anesthesia doctor before surgery. Nicholas walks through the UK study behind the warning, why research-grade retatrutide is a special blind spot, and the week's quick hits. Read the full...
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Gray-market peptides and fentanyl precursors: what the new TRM Labs report found
A blockchain analysis from TRM Labs, published October 6, found that about three in four Chinese chemical vendors it tracked list both peptides and fentanyl precursors, with US buyers sending most of the traceable money. Nicholas walks through the numbers and their limits, the two peptides named…
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WADA's 2027 Prohibited List: what changes for peptides and GLP-1 drugs
The 2027 WADA Prohibited List takes effect January 1. Nicholas covers the new S0 wording that names "peptides" in general, why BPC-157 and TB-500 stay banned, why GLP-1 drugs are still permitted but monitored, and why the reported HHS peptide stopgap changes nothing for tested athletes. Read the...
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Contaminated glutathione injections: what the endotoxin recalls show
Federal agencies are investigating illnesses tied to injectable glutathione made with an ingredient labeled "dietary supplement grade." Brock walks through the recalls, what the FDA and CDC have said so far, and a quick pharmacy-enforcement update. Read the full post: Contaminated glutathione...
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Reported HHS stopgap could open a path to unapproved peptides
A reported HHS stopgap could open a path for compounding pharmacies to dispense some peptides that aren't FDA-approved, while formal rules are written. Brock walks through what's confirmed (the July advisory vote), what's only reported, how thin the human evidence is for the peptides involved…
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New developments in peptide research for weight loss and diabetes
Weight-loss drugs went from about 15% to as much as 28% average weight loss in a few years. Nicholas walks through retatrutide, tirzepatide, semaglutide and CagriSema, plus the caveats. Read the full post: New developments in peptide research for weight loss and diabetes In this episode 00:00…
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Retatrutide's phase 3 TRIUMPH results: what they showed and what comes next
Nicholas covers all four phase 3 TRIUMPH trials of Eli Lilly's triple-hormone drug, why cross-trial comparisons mislead, the new skin side effect, and the filing timeline. Read the full post: Retatrutide's phase 3 TRIUMPH results: what they showed and what comes next In this episode 00:00 Cold…
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How to read a peptide certificate of analysis
Nicholas walks line by line through a peptide certificate of analysis: lot numbers, HPLC purity, identity testing, net peptide content, endotoxin, sterility, ISO 17025 labs and red flags. Read the full post: How to read a peptide certificate of analysis In this episode 00:00 Cold open and intro...
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Growth hormone secretagogues compared: ipamorelin, CJC-1295, tesamorelin and sermorelin
Nicholas compares sermorelin, CJC-1295, tesamorelin and ipamorelin: the two GH signals they copy, their approval histories, the evidence behind each, and shared cautions. Read the full post: Growth hormone secretagogues compared: ipamorelin, CJC-1295, tesamorelin and sermorelin In this episode...
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FDA's 2026 peptide compounding changes, explained
Nicholas breaks down the 503A categories, the April removal of 12 peptides from Category 2, the July advisory votes, and the long rulemaking road before any pharmacy can legally compound them. Read the full post: FDA's 2026 peptide compounding changes, explained In this episode 00:00 Cold open…
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Semax and Selank explained: Russia's nasal peptides
Nicholas covers the two best-known Russian nasal peptides: how they're built, the animal and small human studies behind them, their regulatory status, and the untested analogs Adamax and Adalank. Read the full post: Semax and Selank explained: Russia's nasal peptides In this episode 00:00 Cold…
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Compounded GLP-1s after the shortage: where things stand in 2026
Nicholas explains why compounded semaglutide and tirzepatide were legal, what changed when the shortages ended, the FDA's 2026 crackdown, and questions to ask if you're on a compounded product. Read the full post: Compounded GLP-1s after the shortage: where things stand in 2026 In this episode...
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GHK-Cu and copper peptides: what the skin and hair evidence shows
Nicholas separates topical from injected copper peptides: what GHK-Cu creams have shown in small human studies, the thin hair evidence, AHK-Cu's lab-only data, and the FDA's concerns about injectables. Read the full post: GHK-Cu and copper peptides: what the skin and hair evidence shows In this...
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BPC-157 in 2026: what the evidence actually shows
BPC-157 is called the healing peptide online. Nicholas walks through the animal research, the five small human studies the FDA found, the safety unknowns, and what July's advisory vote does and doesn't change. Read the full post: BPC-157 in 2026: what the evidence actually shows In this episode...
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CagriSema and amylin: what's next after GLP-1s
Amylin is a different fullness hormone from GLP-1. Nicholas covers how cagrilintide works, the REDEFINE 1, 2 and 4 results, and where the CagriSema FDA review stands. Read the full post: CagriSema and amylin: what's next after GLP-1s In this episode 00:00 Cold open and intro 00:36 What amylin is...
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The most-researched peptides of 2026, ranked by evidence
Nicholas ranks twelve of the most-discussed peptides on the MyPeps 1–5 evidence scale, from approved drugs with huge trials to compounds with almost no human data, and explains what the score does and doesn't tell you. Read the full post: The most-researched peptides of 2026, ranked by evidence…
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ABOUT THIS SHOW
Mark and Amy break down the week's peptide research news in plain English: new trials, FDA and WADA decisions, safety alerts, and what the evidence actually shows, including when it doesn't. Every story is sourced, and every episode links to the full write-up on mypeps.info. Mark and Amy are AI-generated voices; every episode is reviewed by our editor, Ryan E., MS. Educational information, not medical advice.
HOSTED BY
MyPeps
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