PODCAST · education
The Poison Lab
by Clinical Toxicology LLC
Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison centers and in the emergency department. Also occasional co-hosted by his robo cohost Toxo! (@LabPoison). This show unpacks the fascinating history, cutting-edge science, and life-saving medical management of toxins from around the globe. From stories of those impacted to expert insights from pioneers in poisoning treatment, each episode brings you closer to understanding the poisons that lurk in plain sight. Explore episodes, med videos, games, and more at thepoisonlab.com—every poison has a story to tell!
Episodes
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The Poison Lab Update: What’s Next + a Kratom Research Bonus
A quick Poison Lab update: new episodes are in the works, including a forthcoming NACCT research episode—though Ryan is briefly buried under mushroom-poisoning programming, NACCT, travel, and the start of a new academic year. In the meantime, revisit the back catalog, including outbreak episodes,...
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A Morel Dilemma: Episode 7 — What We Know Now
After weeks of investigation, the Bozeman outbreak is contained, but the questions it raised are much harder to close. In the final episode of A Morel Dilemma, we return to Montana to understand how investigators traced the mushrooms, looked for additional cases, communicated risk to the public,...
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A Morel Dilemma- Bonus: Emergency Mushroom Identificaiton
When someone eats a mushroom and starts to feel sick, the first instinct is often to figure out exactly what mushroom it was. But mushroom identification is harder, riskier, and more specialized than most people realize. In this bonus episode of A Morel Dilemma, we look at what actually happens...
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A Morel Dilemma: Episode 6 — The Signal
The Bozeman outbreak was the first loud signal, but it was not the only one. After the CDC report, toxicologists in other countries started looking back through their own poison center data and found something unsettling: more patients with severe illness after eating morels, including cases of...
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A Morel Dilemma Episode 6...Is Coming
Hey everyone, it’s Ryan. I know many of you are patiently waiting for Episode 6 of A Morel Dilemma, and it is coming next week. I genuinely cannot wait for you to hear this one. But it is actually available right now for supporter members. You can go to www.thepoisonlab.com/support and get every...
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A Morel Dilemma Preview: Supporting Member Bonus Episodes
This preview features the opening conversations from two supporting member bonus episodes in The Poison Lab outbreak series. First, we head to Ontario, where a mass aconite poisoning unfolded after a restaurant spice was contaminated with one of the most dangerous plant toxins in the world. Then…
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A Morel Dilemma Bonus Radio Co-Broadcast: Ryan Feldman on WTMJ Conversations — Morels, Mushroom Poisoning, and the Story Behind A Morel Dilemma
In this bonus episode of A Morel Dilemma, Ryan shares his recent interview on WTMJ Conversations with Libby Collins. The conversation goes behind the scenes of the series and explores why Ryan spent two years investigating the 2023 Bozeman, Montana morel mushroom outbreak, one of the strangest...
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A Morel Dilemma: Episode 5 — Trial of the Morel
The case against the morel mushroom is starting to come together, but there are still major problems. Not everyone who got sick ate morels, and not everyone who ate morels got sick. If the mushroom is really the culprit, those gaps have to be explained. In Episode 5 of A Morel Dilemma, we put the...
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A Morel Dilemma: Episode 4 — A Familiar Shape
When every obvious test comes back negative, investigators have to look for another way to prove what caused the outbreak. So this episode takes a step sideways, from Bozeman, Montana to a small mountain village in the French Alps, where researchers faced a different kind of mystery: a cluster of...
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A Morel Dilemma: Episode 3 — Testing the Evidence
With the restaurant closed and the first interviews underway, investigators bring in the CDC and FDA to help answer the question at the center of the outbreak: what actually made people sick? The leading suspect is still the morel mushroom, but proving that is not simple. The symptoms could fit...
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A Morel Dilemma: Bonus — The Bradford Hill Criteria & The Morel
In Episode 5, we put the morel mushroom on trial. This bonus episode shows how we built the case. Dr. Grant Comstock joins me for the full, unfiltered causation breakdown using the Bradford Hill criteria, a public health framework used to separate true causation from simple association. We walk...
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A Morel Dilemma: Bonus — Calling in The CDC
In this bonus episode, we go deeper into the public health machinery behind a mass poisoning investigation. Dr. Michael Yeh, a medical toxicologist at the CDC’s National Center for Environmental Health, explains how the CDC gets pulled into unusual outbreaks, how poison centers and health...
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A Morel Dilemma: Bonus — Who Treats Mushroom Poisoning
Who actually treats mushroom poisoning? In this short mini episode, we answer a surprisingly important question: when someone gets sick after eating a mushroom, who do they call, and who helps the doctors figure out what to do next? We break down the role of poison centers, medical toxicologists,...
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A Morel Dilemma: Bonus — Remembering poisonous mushrooms (GOTTA PICCEM)
In this bonus episode, Dr. Rob Bassett from Philadelphia Poison Control walks us through one of the most useful teaching tools in mushroom toxicology: GOTTA PICCEM. This mnemonic organizes toxic mushrooms by their clinical syndromes and, most importantly, by the timing of symptom onset. That…
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A Morel Dilemma: Bonus — Muscarine Poisoning
This bonus episode takes a deeper look at the muscarine poisoning case discussed by Dr. Matthew Stanton. We break down how muscarine causes toxicity, why its symptoms can become life-threatening, and why its important for foragers to recognize so they can be treated. Select References: Dr....
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A Morel Dilemma: Episode 2 — Investigations and Falsehoods
As reports of severe illness and death come in, the Bozeman outbreak moves from medical mystery to full public health investigation. Local and state investigators race to identify the source, shut down the risk, interview patients, collect food samples, and figure out whether anyone else could...
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A Morel Dilemma: Episode 1 — Outbreak in Bozeman
A deadly outbreak begins with a single meal at a sushi restaurant in Bozeman, Montana. Within hours, diners develop severe nausea, vomiting, and diarrhea. Some collapse. Two people die. At first, it looks like food poisoning, but investigators quickly notice one strange ingredient connecting many...
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Introducing: A Morel Dilemma
Available June 3rd- A deadly outbreak begins at a sushi restaurant in Bozeman, Montana. Diners develop rapid, severe gastrointestinal illness. Some collapse. Two people die. And the only clue pointing investigators toward a cause is also the hardest one to believe: morel mushrooms. A Morel…
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Gas Station Heroin? Kratom, Regulation, and Recovery — A Co-Broadcast with the Kratom Sobriety Podcast
In this special co-broadcast episode, The Poison Lab joins forces with The Kratom Sobriety Podcast for a deeper conversation about kratom, regulation, addiction, recovery, and what poison center data can tell us about real-world harm. Kratom is a plant-derived substance that contains mitragynine...
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Outbreak: 75 Fatalities After a Funeral Poisoning in Mozambique
In this episode of The Poison Lab Outbreak, Ryan talks with Dr. Alaina Steck about a devastating mass poisoning in Mozambique that began at a funeral and ultimately sickened more than 200 people, with a fatality toll of over 70. Early reports blamed crocodile bile. Others suspected intentional...
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Rebroadcast: Phenibut. The emerging drug you don’t know about (yet)
Phenibut is an emerging and unfamiliar drug taking hold in the US that is readily available online and legal to obtain. It acts as a GABA-B agonist and carries risks of dependency and withdrawal. In this episode Ryan interviews phenibut users as well as experts involved in phenibut treatment.…
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If I had a Nickel (Mystery Case) & Toxicologist vs The internet (#13) with Dr. Damilola Idowu-Ellsworth
In this episode of The Poison Lab, host Ryan Feldman is joined by medical toxicologist Damilola Idowu‑Ellsworth for a fast-moving, case-heavy conversation packed with clinical pearls, listener participation, and classic toxicology weirdness. The show opens with listener guesses for the previously...
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Poison Lab Update: Mushroom Poisoning Radio Roundup
Hey everybody, you’re listening to The Poison Lab—well, almost. We’ve got a new episode coming next week, but we’re running a little behind on our usual release schedule because… life happens. That said, if you’re looking for some toxicology content right now, I’ve got you covered. Recently, I…
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Sick at Work? A Poisonous Cause of Coworker Illness?
Do you think you know the cause of these symptoms? Send your guesses to [email protected] to take part in the next episode A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus...
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Outbreak: Thebaine Poisoning from Poppy Seed Tea in Australia
In November 2022, hospitals across Australia began seeing patients with sudden rigidity, spasms, seizures—and in some cases cardiac arrest—after drinking homemade poppy seed tea. The source? Food-shelf poppy seeds contaminated with extraordinarily high levels of thebaine, an opioid alkaloid that...
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Poisonous Fungus Amongus is Here— The Rhyming Kid (or Adult) Book For Mushroom Safety
Get your copy here! https://a.co/d/8QUBmQy Want to hear it with insights from the author?: • Poisonous Fungus Among Us | Full Children’... Don't have time for the full thing: check the highlights: • Poisonous Fungus Amongus Highlights Reel Want a clearer picture: Full reading large scale here: •...
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LIVE from Chicago: 2025 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology
Show Notes In this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the conference to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and...
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Toxicologist vs The internet (#12) with Dr. Joe Kennedy MD
In this episode of The Poison Lab, host Ryan Feldman is joined by Dr. Joe Kennedy, medical toxicologist at the University of Vermont and consultant for the Northern New England Poison Center. Together they work through real poisoning cases to sharpen toxic differentials, sum up practical...
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GOTTA PICCEM is Here! — The Poisonous Mushroom Card Game Launch
GOTTA PICCEM: The Poisonous Mushroom Card Game 👉 Order now right here OR go to www.gottapiccem.com and click "Buy GOTTA PICCEM" Why this is awesome What started as a nerdy teaching tool made to teach mushroom poisoning by folks who treat mushroom poisoning is now a full-fledged card game—equally...
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Ryan is LIVE on the Radio Thursday July 17th 11:45AM-12:30 PM CST WPR Larry Meiller Show!
Listen here (https://www.wpr.org/shows/larry-meiller-show) to hear Ryan Live on AIR for the Larry Meiller show, Thursday July 17th 11:45AM-12:30 PM CST. Check this "Listen Live" link if your having trouble!
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Poisoning Outbreak: Aconite Poisoning at Markham, Ontario Restaurant
A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card game The GOTTA PICCEM Poisonous Mushroom Game!...
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MURDER for Lunch: Toxicologist vs The internet (#11) with Dr. Amy Zosel MD
In this episode of The Poison Lab, host Ryan Feldman is joined by Dr. Amy Zosel, a medical toxicologist, emergency physician, and educator. Together, they use real poisoning cases to practice identifying toxins and flexing their toxic differential The conversation dives into intriguing and...
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A Mnemonic For Poisonous Mushrooms and Their Effects- GOTAA PPICEM
A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card game The GOTTA PICCEM Poisonous Mushroom Game!...
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Leafy Greens & Injured Beans: Natures Nephrotoxins – A Poison Lab & NephMadness Collaboration
In this special collaboration with NephMadness, we're diving into the world of nephrotoxins with an expert panel from Virginia Commonwealth University. NephMadness is an educational competition modeled after March Madness, and this year, one of the featured regions focuses on plant-based...
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A Mysterious Case of Weakness, Low Potassium, and Kidney Injury
Do you think you know the cause of these symptoms? Send your guesses to [email protected] to take part in the next episode Support the show! Rep the show! Show website
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Should we Give Naloxone in Cardiac Arrest? Insights From the Authors of Three Key Studies
Finally, the journal club to rule ALL journal clubs. In this episode of The Poison Lab, we tackle one of the biggest topics in emergency medicine and toxicology: Should naloxone be given during opioid-associated cardiac arrest? With three fantastic studies published in 2024, we’re diving into the...
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The Poison Lab Holiday Bonus- Stump The Toxicologist Reel 2022
In this special holiday bonus episode, Ryan takes a look back at some of the most captivating episodes of The Poison Lab from 2022. Get ready for an ultimate test of your toxicology differential diagnosis skills as we compile all the "Stump the Toxicologist" segments into one streamlined,...
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What Should We Do About Forever Chemicals? With Dr John Downs (The Wizard of PFAS)
Join host Ryan Feldman in an insightful episode of "The Poison Lab" as he sits down with Dr. John Downs, Director of the Virginia Poison Center, and one of the leading experts on per- and polyfluoroalkyl substances (PFAS), commonly known as "forever chemicals." Known for their persistence in the...
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Poison Updates: Newsletter, Poison Ads?, and Guest Spots on 22 at the Lips and The Continuing Studies Podcast
Ryan on others shows Ryan on "22 at the Lips" Ryan on "Continuing Studies" A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways…
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LIVE from Denver: 2024 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology
In this exciting live episode from the 2024 North American Congress of Clinical Toxicology (NACCT) in Denver, Ryan dives into 12 of the most impactful research abstracts presented at the conference directly with the authors themselves. Covering a wide range of toxicology topics—from the NACSTOP2...
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The Poison Letter To The Editor: Listener Critiques and Author Responses for The AHA 2023 Life Threatening Poisoning Guidelines with Dr. Michael Mullins, Dr. Donna Seger, Dr. Leon Gussow, and Dr. Eric Lavonas
In this episode the poison lab hosts scientific discourse . Three listeners (Dr. Michael Mullins, Dr. Donna Seger, and Dr. Leon Gussow) write in their critiques surrounding specific recommendations and language used with the AHA 2023 Management of Poisoning Cardiac Arrest or Life-Threatening...
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Send in Your Questions For "Ask a Toxicologist"
Have a burning question you have always wanted to ask a toxicologist? What are tips for managing an anticholinergic overdose? What is the deadliest poison? Why are they called lead pencils if there is no lead?! Send your questions in to [email protected] to take part in a future episode! (If you...
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Open and Shut (Mystery case 31) with Guests Dr. Dan McCabe and Dr. Crissy Lawson
In this episode Ryan is joined by two expert guests to help read listener guesses for the cause of this poisoning murder and shed light on the toxin involved in the case, which puzzled medicolegal investigators. Ryan is joined by Dr. Dan McCabe, MD (emergency medicine physician, medical...
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The Poison Lab - Stump The Toxicologist Reel 2023
In this bonus episode Ryan highlights some of the great episodes done in 2023 and compiles ALL of the stump the toxicologist segments from 2023 into one easy to consume episode. Test your toxicology differential skills with more than six poisoning cases. Check out the actual episodes for more...
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A Mysterious Case of Fatal Arrhythmia in a Newly Wed (Episode #31 Mystery Case)
Do you think you know the cause of these symptoms? Send your guesses to [email protected] to take part in the next episode Support the show! Rep the show! Show website
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Where is Episode #31 and Bonus Episodes- Ryan Joins "The Larry Meiller Radio Show" and The "EMS2020" Podcast
A quick update to share some other shows Ryan has been on in the last few weeks! Check the show notes for links to each episode! Ryan on "The Larry Meiller Show" discussing delta cannabanoids Link to stream Link to download Ryan on EMS2020 talking prehospital overdose Link to episode Show…
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Bromazolam, Etonitazene, and Carfentanil Walk into a Bar – Trends in Novel Illicit Drugs with Dr. Alex Krotulski
In this episode Ryan interviews Dr. Alex Krotulski PhD from the Center for Forensic Science Research and Education. Together take a look at trends in novel opioids, benzodiazepines, stimulants, hallucinogens, synthetic cannabinoids, and "hemp products" that are showing up in your patients, drug...
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Inefficient Heat (Mystery Case 29) & Toxicologists vs The internet (#10) with Dr. Ann Arens
Dr. Ann Arens, MD an emergency medicine physician and medical toxicologist with Oschner Medical center in New Orleans, LA joins the show to educate us on some HOT toxins, solve toxic cases, and opine on the philosophical and existential reasons drugs even exist. Tune in for a fantastic discussion...
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A Mysterious Case of Fatally High Temperature and Organ Failure in a Young Woman (Episode #29 Mystery Case)
Do you think you know the cause of these symptoms? Send your guesses to [email protected] to take part in episode 29 A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content...
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A very NACCT Holiday-2023 North American Congress of Clinical Toxicology High Yield Abstract Review
In this episode Ryan is joined by a guest panel (Dr. Grant Comstock MD, Dr. Joshua Trebach MD, Dr. Emily Kiernan DO, and Dr Frank Paloucek PharmD, DABAT) to review nine of the most interesting or clinically impactful research abstracts that were presented at the 2023 North American Congress of...
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ABOUT THIS SHOW
Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison centers and in the emergency department. Also occasional co-hosted by his robo cohost Toxo! (@LabPoison). This show unpacks the fascinating history, cutting-edge science, and life-saving medical management of toxins from around the globe. From stories of those impacted to expert insights from pioneers in poisoning treatment, each episode brings you closer to understanding the poisons that lurk in plain sight. Explore episodes, med videos, games, and more at thepoisonlab.com—every poison has a story to tell!
HOSTED BY
Clinical Toxicology LLC
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