LIVE from Denver: 2024 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology

In this exciting live episode from the 2024 North American Congress of Clinical Toxicology (NACCT) in Denver, Ryan dives into 12 of the most impactful research abstracts presented at the conference directly with the authors themselves. Covering a wide range of toxicology topics—from the NACSTOP2 trial on acetaminophen overdose, ECG intervals, cannabis toxicity in young children, and more—each guest breaks down their study’s findings and clinical relevance. If you missed the conference or want a deeper understanding of the year's most important toxicology research, this episode is for you. Check the show notes for links to the published abstracts, the full list of studies discussed, and time stamps for where you can find those studies.Link to published abstract manuscriptAbstracts07:48-Abstract #1. The NACSTOP2 trial: a multi-center randomized controlled trial investigating the early cessation of n-acetylcysteine in acetaminophen overdoseGuest- Dr. Anslem Wong, MD, PhD21:33- Abstract #36. ECG intervals: does one size really fit all?Guest- Dr. Caitlin Roake, MD, PhD25:41- Abstract #85. Do abnormal electrocardiographic intervals predict death in poisoned patients older than 65 years?Guest- Dr. Michael Chary, MD30:06- Abstract #61. Minimum tetrahydrocannabinol dose that produces severe symptoms in children <6 years old with cannabis edible ingestionsGuest- Dr. Keahi Horowitz, MD36:25- Abstract #114. Frequency and severity of cannabis toxicity before and after legislative change to increase cannabis edible package sizeGuest- Dr. Robert Hendrickson, MD38:24- Abstract #101. Quantification of acetaminophen line-crossers in the setting o f overdose with delayed gastric absorptionGuest- Dr. Jamie Sterr, PharmD41:41- Abstract #175. Cause for pause: bradycardia induced by transdermal rivastigmine in anticholinergic deliriumGuest- Dr. Santiago Batista Minaya, MD46:21- Abstract #199. Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) Syndrome with poor neurological outcome in the setting of suspected opioid useGuest- Jack Yang and Dr. Avery Michienzi, DO49:49- 191. Severity scores for caustic injury: Zargar they even used?Guest- Dr. Amar Chakrabortya, MD53:!2- Abstract #9. Disparity in immune-mediated reactions to Crotalidae polyvalent immune fab (ovine) and Crotalidae immune F(ab’)2 [equine] in alpha-gal endemic regions and alpha-gal sensitized adultsGuest- Dr. Ari Filip, MD59:10- Abstract # 26. Acute propranolol overdose and dose thresholds of severe toxicityGuest- Dr. Katherine Isoardi, MBBS1:06:05- 28. Risk of serotonin toxicity following acute lamotrigine overdoseGuest- Dr. Angela Chiew, MBBS, PhD (Introduction at 1:00:00)1:12:36- Interview with AACT President ElectGuest- Dr. Jillian Theobald, MD, PhDA Morel DilemmaSupport the showReview the show where ever your listeningGet Messages from Toxo (Join the Newsletter!)Join as a supporting memberAd free episodesBonus content and early accessDiscounts and give aways on GOTA PICCEM Mushroom card gameThe GOTTA PICCEM Poisonous Mushroom Game!The Poisonus Fungus Amongus Children's Book!Full book reading (6 minutes!)Tox trinkets (Rep the show at home!)Reach the showEmail: [email protected] Show ResourcesRyan's Medical Games and ResourcesShow Website