PODCAST · science
The Rounds Table
by Dr. John Fralick and Dr. Michael Fralick
The Rounds Table is a free recurring medical podcast covering the latest and most important research from major medical journals. It is intended for all practicing healthcare professionals and aims to to help them keep up to date in the care of their patients.
Episodes
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Episode 151 - An Update
Send us Fan Mail 1)https://mountpleasantgroup.permavita.com/site/DrMichaelPaulFigueroaFralick.html 2)https://deptmedicine.utoronto.ca/news/memoriam-dr-michael-paul-figueroa-fralick
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Episode 150 - Metformin for Knee Osteoarthritis
Send us Fan Mail Welcome back Rounds Table Listeners! In this solo episode, Dr. Mike Fralick discusses a recent trial looking at metformin for knee osteoarthritis in patients with overweight or obesity. Here we go! Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A...
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Episode 149 - The Mediterranean Diet for IBS
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining the effect of a Mediterranean diet, compared with traditional dietary advice, on irritable bowel syndrome (IBS). Here we...
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Episode 148 - Caffeinated Coffee Consumption vs. Caffeine Abstinence for Recurrent AF
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining the effect of caffeinated coffee consumption compared with abstinence from coffee and caffeine on recurrent atrial...
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TBT - Top 5 Drug Interactions You Are Missing with David Juurlink
Send us Fan Mail Happy New Year, Rounds Table Listeners! In this throwback episode (initial release 29 May 2025), Dr. Mike Fralick and special guest Dr. David Juurlink, pharmacologist and internist, Professor of Medicine at the University of Toronto, and head of the Clinical Pharmacology and...
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Episode 147 - Top 5 Papers of 2025
Send us Fan Mail Welcome back Rounds Table Listeners! In our year-end episode, Drs. Mike and John Fralick discuss five important research studies published in 2025: Apixaban for Extended Treatment of Provoked Venous Thromboembolism (HI-PRO) (0:00 – 4:20) Tirzepatide for Heart Failure with…
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Episode 146 - Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction
Send us Fan Mail Welcome back Rounds Table Listeners! In this solo episode, Dr. Mike Fralick discusses a recent meta-analysis examining beta-blockers after myocardial infarction in patients with an ejection fraction of at least 50% and no other indications for beta-blocker therapy. Here we go!...
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Episode 145 - Noninvasive BP Monitoring vs. Arterial Catheter in Patients with Shock
Send us Fan Mail Welcome back Rounds Table Listeners! In this solo episode, Dr. Mike Fralick discusses a recent trial examining whether noninvasive blood-pressure monitoring is noninferior to early insertion of an arterial catheter in patients with shock admitted to the ICU. Here we go! Deferring...
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Episode 144 - Rituximab for EGPA
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial comparing rituximab with conventional strategy for the induction of remission in patients with eosinophilic granulomatosis with...
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Episode 143 - Beyond Radiology with Yatin Chadha
Send us Fan Mail Welcome back Rounds Table Listeners! This week, Dr. Mike Fralick welcomes returning guest Dr. Yatin Chadha, radiologist at North York General Hospital and founder of the beyond MD podcast, to chat about Dr. Chadha's recently launched online course series beyond Radiology. Here we...
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Episode 142 - Continuing vs. Withholding RAS inhibitors before Surgery
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent systematic review and meta-analysis that looks at continuing versus withholding RAS inhibitors before noncardiac surgery. Here we go! Evaluating the risks and...
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Episode 141 - Spironolactone in Patients on Maintenance Dialysis and Prophylactic Antibiotics for Upper GI Bleed in Cirrhosis
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of spironolactone on heart failure and cardiovascular death in patients undergoing maintenance dialysis, and...
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TBT - Airway Management in Acute Poisoning and the PALACE Trial
Send us Fan Mail Welcome back Rounds Table Listeners! In this throwback episode (initial release 14 Mar 2024), Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast, discuss two papers: one exploring the role of non-invasive ventilation in comatose patients...
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Episode 140 - Spironolactone vs. Amiloride for Resistant Hypertension
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent trial examining whether amiloride is noninferior to spironolactone in reducing systolic blood pressure in patients with resistant hypertension. Here we go!...
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Episode 139 - Semaglutide in Alcohol Use Disorder
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent phase 2 trial looking at the effects of once-weekly semaglutide on alcohol consumption and craving in adults with alcohol use disorder (AUD). Here we go!...
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Episode 138 - Preparing for Internal Medicine Clerkship
Send us Fan Mail Welcome back Rounds Table Listeners! This week, Dr. Mike Fralick sits down with Mihir Pandya, a third-year medical student at Western University. Mihir picks Mike’s brain for advice on preparing for internal medicine clerkship: What’s the best approach to acquire knowledge on the...
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Episode 137 - Fecal Transplant in Primary C. difficile
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining fecal microbiota transplantation (FMT) in primary C. difficile infection. Here we go! Fecal Microbiota Transplantation...
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Episode 136 - Aspirin in Patients with Chronic Coronary Syndrome receiving Oral Anticoagulation
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial looking at aspirin in patients with chronic coronary syndrome receiving oral anticoagulation. Here we go! Aspirin in Patients with Chronic...
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Episode 135 - Top Papers from the 2025 European Society of Cardiology (ESC) Congress
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Drs. Mike and John Fralick discuss some of the top papers from the 2025 European Society of Cardiology (ESC) Congress. Hot off the presses, here we go! Increasing the Potassium...
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Episode 134 - Rounds Table x I'm Pharmacy: Tableside Chat with Mina Tadrous
Send us Fan Mail Welcome back Rounds Table Listeners! This week, Dr. Mike Fralick sits down with Dr. Mina Tadrous, a pharmacist, researcher, Assistant Professor at the University of Toronto's Leslie Dan Faculty of Pharmacy, and host of the I'm Pharmacy podcast. If you're curious about what it…
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Episode 133 - Dexamethasone for Bacterial Meningitis
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a throwback trial of dexamethasone in adults with acute bacterial meningitis. Here we go! Dexamethasone in Adults with Bacterial Meningitis (0:00 – 11:19). Questions?...
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Episode 132 - Mifepristone for Type 2 Diabetes and Hypercortisolism
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the effects of mifepristone on glycemic control in adults with inadequately controlled type 2 diabetes and hypercortisolism. Here…
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Episode 131 - Zoledronate for Fracture Prevention and Semaglutide in Type 1 Diabetes and Obesity
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of infrequent zoledronate administration on vertebral fracture prevention in early postmenopausal women, and the...
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Episode 130 - Hypotension-Avoidance vs Hypertension-Avoidance and Albuterol–Budesonide in Mild Asthma
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive...
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Episode 129 - Antihypertensive Medication Timing
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining the effect of bedtime vs morning administration of antihypertensive medications on major cardiovascular events and death....
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TBT - The Top 5 Papers of 2024
Send us Fan Mail Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024: Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09) Tirzepatide for the...
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Episode 128 - Finerenone with SGLT2 inhibitors for CKD and Type 2 Diabetes
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons...
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Episode 127 - Leukocytoclastic Vasculitis with Karim Ladak
Send us Fan Mail Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. Karim Ladak—rheumatologist and internist, Clinical Assistant Professor at McMaster University, and host of the Rheumatology for the Royal College...
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Episode 126 - Sotatercept for Pulmonary Arterial Hypertension
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial exploring the effects of add-on sotatercept in patients with advanced pulmonary arterial hypertension and a high risk of death.…
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Episode 125 - Top Papers from the 2025 American Diabetes Association (ADA) Session
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go!...
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Episode 124 - 2024 KDIGO Clinical Practice Guidelines for Chronic Kidney Disease
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have the next episode in our Clinical Practice Guidelines series. Drs. Mike and John Fralick discuss the top takeaways from the 2024 KDIGO Clinical Practice Guidelines for chronic kidney disease. Here we go! 1. KDIGO 2024 Clinical...
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Episode 123 - Trial Files Top 5 RCTs
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15…
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Episode 122 - Opioids vs. Non-Opioids for Chronic Pain, IV Albumin for SBP, and PPI for GI Bleed
Send us Fan Mail Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids…
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Episode 121 - Tirzepatide vs. Semaglutide for Obesity
Send us Fan Mail Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published head-to-head trial exploring the safety and efficacy of tirzepatide compared to semaglutide for obesity management. Here we go! Tirzepatide as...
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Episode 120 - Top 5 Drug Interactions You Are Missing with David Juurlink
Send us Fan Mail Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. David Juurlink, pharmacologist and internist, Professor of Medicine at the University of Toronto, and head of the Clinical Pharmacology and Toxicology...
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Episode 119 - Semaglutide for MASH
Send us Fan Mail Welcome back, Rounds Table Listeners! This week we have a solo episode with Dr. John Fralick, discussing a recently published trial of the GLP-1 receptor agonist semaglutide for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Here we go! Phase 3 Trial of...
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Episode 118 - Lorundrostat for Uncontrolled Hypertension
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the safety and efficacy of lorundrostat (an aldosterone synthase inhibitor) in treatment of uncontrolled and...
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Episode 117 - Brensocatib for Bronchiectasis and Alteplase for Posterior Circulation Ischemic Stroke
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast. This week, Dr. Mike Fralick and special guest Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration discuss two recent papers: the use of…
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Episode 116 - 2025 ACC/AHA Clinical Practice Guidelines for Acute Coronary Syndrome
Send us Fan Mail Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Clinical Practice Guidelines series. This week, Drs. Mike and John Fralick discuss the 2025 ACC/AHA Clinical Practice Guidelines for Acute Coronary Syndrome. Here we go! 2025...
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Episode 115 - Tirzepatide for Obesity Treatment and Diabetes Prevention
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go! Tirzepatide for...
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Episode 114 - Liberal Fluid Intake versus Fluid Restriction in Chronic Heart Failure
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining liberal fluid intake vs. fluid restriction in chronic heart failure. Here we go! Liberal fluid intake versus fluid...
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Episode 113 - Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS)...
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Episode 112 - Top Papers from the 2025 American College of Cardiology (ACC) Session
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss top papers from the 2025 American College of Cardiology (ACC) Annual Scientific Session. Hot off the presses, here we go! Extended Reduced-Dose...
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Episode 111 - Resmetirom in MASH with Liver Fibrosis and Mediterranean Diet in Ulcerative Colitis
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Dr. John Fralick and guest host Dr. Chunpeng Nie discuss two recent papers: resmetirom for the treatment of Nonalcoholic Steatohepatitis (NASH)—now known as Metabolic...
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TBT - The Top 5 Papers of 2023
Send us Fan Mail Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2023: Hydrocortisone in Severe Community-Acquired Pneumonia (0:00 – 5:39). Tirzepatide vs Insulin Lispro Added to Basal Insulin in…
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Episode 110 - Restrictive versus Liberal Transfusion in Myocardial Infarction with Dr. Jeff Carson
Send us Fan Mail Welcome back Rounds Table Listeners! We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Jeffrey Carson, Distinguished Professor of Medicine at the Rutgers Robert Wood Johnson Medical School and Provost at Rutgers University, to chat about…
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Episode 109 - GLP1 Receptor Agonists in Parkinson's Disease
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers examining the effect of glucagon-like peptide-1 receptor agonists (GLP1's) on patients living with Parkinson’s disease. Two...
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Episode 108 - Endovascular Treatment in Stroke with Medium Vessel Occlusion
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he will discuss a paper exploring endovascular treatment (EVT) for acute ischemic stroke due to medium-vessel occlusion. Here we go! Endovascular Treatment of Stroke Due…
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Episode 107 - Point-of-Care Diabetes Management in Hospital and Tirzepatide in Heart Failure
Send us Fan Mail Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers - the role of continuous glucose monitoring for diabetes management in hospital and the benefit of tirzepatide in patients...
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Episode 106 - Screening for Diabetes and Dyslipidemia after Pregnancy Complicated by Hypertension or Diabetes with Dr. Amy Yu
Send us Fan Mail Welcome back Rounds Table Listeners! We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat…
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ABOUT THIS SHOW
The Rounds Table is a free recurring medical podcast covering the latest and most important research from major medical journals. It is intended for all practicing healthcare professionals and aims to to help them keep up to date in the care of their patients.
HOSTED BY
Dr. John Fralick and Dr. Michael Fralick
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