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The Startup Ideas Podcast

by Greg Isenberg

Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out. For more startup ideas, we created a database of 30+ startup ideas you can take at https://gregisenberg.com/30startupideas

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Episodes

  1. The 9 Stages of AI Agent Adoption, Explained

    In this solo episode, I break down the war on AI agents, from Amazon blocking Meta's Muse to Delta treating outside booking agents as unauthorized automated activity to Yelp charging agents for access. I share how I think about an agent, as a customer with a credit card who reads your site…

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  2. Making $$$ with Meta Muse AI

    Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP In this solo episode, I break down how to make money with Meta Muse by mining Facebook groups, Marketplace, and Instagram to match buyers with sellers. The idea came after my wife and I had a baby and the agency we hired…

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  3. Gemini 4 Argon: AI Marketing, 3D Printing and SaaS

    Gemini 4 Argon is LIVE, Google's most advanced AI model, try it for yourself: https://startup-ideas-pod.link/gemini4-argon In this solo episode, I share what I learned after a week with Gemini 4 Argon, Google's new frontier model. I show three places it shines: marketing with AI, physical AI, and...

  4. 8 GitHub Repos To Go Viral and Make Money

    In this solo episode, I walk through eight GitHub repos and AI skills that I test at night and on weekends. The list covers launch videos, social research, local voice and dubbing, editable decks, agent teams, lead-magnet tools, idea stress-testing, and design guidance. For each one, I explain…

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  5. How Will People Make Money in the AI Age?

    In this solo episode, I walk through the 13 businesses I think are left to build in the agentic era. I believe that in a world of agents and abundance, owning the right assets puts you in a better position. For each business, I explain what it is, why it holds up in a world of agents, and one or...

  6. Become a $1M/yr FDE (Full Course)

    Google's most advanced audio models are LIVE, try them for yourself: Gemini 3.8 Live: https://startup-ideas-pod.link/gemini-3.8-live Gemini 3.5 Transcribe https://startup-ideas-pod.link/gemini-3.5-transcribe Gemini 3.5 Live Translate: https://startup-ideas-pod.link/gemini-3.5-live-translate In…

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  7. OpenAI DevDay: Dots, Agents & $100B Opportunities

    I watched almost 60 minutes of Sam Altman on stage at OpenAI Dev Day 2026. Out of 20-plus launches, I pick the three or four that I think can make people billions of dollars in aggregate. I break down Dots, OpenAI's personal agent platform, plus the Decisions API, the Agents API with computer…

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  8. $5T opportunity: AI Roll Ups

    In this solo episode, I break down the $5 trillion wave of small businesses set to change hands as their owners retire, and why AI agents make this wave a real opening for solo founders. I walk through how Thrive Holdings and General Catalyst buy accounting firms, property managers, and support...

  9. Muse AI Connectors: The Next App Store Moment?

    In this solo episode, I break down the huge business opportunity because Meta has opened Muse, its personal AI agent, to developers. You can now submit a connector, which lets Muse use your service when someone asks it for help, and I think this could be the app store moment for AI. I explain how…

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  10. The Right Way To Write With AI

    Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP In this episode I speak with Nicholas Cole about the real value of everything you write on the internet. Cole has 15 years of experience as a nonfiction writer and ghostwriter, and he runs the SaaS platform Typeshare. He...

  11. Jev is HERE. How to use it

    In this episode, I talk with Ryan Vogel about Jev, a new type of AI built for classification. Ryan shows how Jev takes an input plus an output schema and returns a probability for each choice in about 200 milliseconds. He demos Jev sorting 1,700 emails for 18 cents total, then covers lead…

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  12. Instinct AI: The AI Assistant for normal people

    I sit down with Remy to go through Instinct, the new invite-only personal agent that runs inside iMessage. Remy shares his raw chat history on screen: a haircut booking in Copenhagen, a restaurant reservation, a Bali visa on arrival, and an Emirates Skywards sign-up. We cover the parts that…

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  13. Building a Software Factory that actually works (Full Course)

    Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP I welcome Ras Mic back to the pod to explain the phrase "software factory." Mic shares his screen and walks through the exact system that he runs today. His factory has four steps: isolate, build, prove, and ship. He keeps...

  14. You're using GPT-6 Astra WRONG

    I talk with Ras Mic about GPT-6 Astra. We skip the game demos and the 3D toys, and we focus on use cases to earn money or improve products. I share 9 Astra prompts that I posted publicly, and Greg Brockman reposted. Ras then shows his hardware project: he moved from a speaker idea to a parts…

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  15. Local AI Clearly Explained

    I run this episode solo. I explain local AI in plain terms: the model runs on hardware I control, and a cloud model runs somewhere else. I map the four pieces of the local AI landscape — the model, the warehouse, the software, and the workflow — and I define the words that beginners meet first:...

  16. These 5 Github Repos are a goldmine

    On this solo episode, I review five free, open source GitHub repos that help you build products, make money, or save time: Peter Yang's No AI Slop Skill, the CRM by TryComp AI, Video Use by browser use, SkillSpector by NVIDIA, and Phone Harness. For each repo I explain what it does, why it…

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  17. Making $$$ as a Marketing Engineer

    In this solo episode I explain a role that I call the marketing engineer. I believe this person becomes one of the most valuable hires in tech in the next 18 to 24 months. I define the job, I show the four eras of marketing that lead to it, and I give the tool stack that makes it work. I use a...

  18. WebMCP clearly explained (and how to make $$)

    Vinny is back on the pod, and he explains WebMCP. WebMCP puts MCP tools inside the browser UI, so any agent that you bring can read a page and act on it. Vinny demos an espresso gear store where his agent compares two machines, checks the counter width, matches accessories, adds an item to the...

  19. Screensharing top takes in AI/startups

    On this week’s SIP Live we dive deep on the X timeline to give each post a sip or a skip, and we answer questions from the chat. This episode covers AI-native operations, a baby food app that earns a million dollars a month, iMessage agents, human customer support as a brand advantage, small…

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  20. Grok Bot: make a 1 person company with agents

    I sit down with Billy Howell for an inside look at a real business that runs on Grok Bot agent teams. Billy tests hundreds of tools for The Rundown, and he uses Grok Bot to run his local newsletter, The Arlington Bagel, which goes to 6,000 readers every Thursday. He walks me through his chief of...

  21. You need to be skillsmaxxing (10x your Claude/Codex)

    Get Your Complete Financial OS at https://startup-ideas-pod.link/brex_SIP I talk with Remy, known online as AI with Remy, about agent skills and how to share them across a whole team. Remy explains that a skill is an SOP for AI: a markdown file that teaches Claude your exact way to do a task. He...

  22. How to use Claude Code better than 99% of People

    Get Claude Code: https://startup-ideas-pod.link/claude-greg In this solo episode I lay out the exact system I use to turn Claude Code into what I call an AI employee. My premise is simple: give Claude the same things you would give a person joining your company (a workspace, memory, a brief, a...

  23. How to Build an AI-Native Company in 2026

    I sit down with Allie K. Miller to talk about the shift from managing AI agents to enabling them. Allie runs a workforce of 34 AI agents led by an AI chief of staff named Simon, plus six directors named after Friends characters. She shares her three-word prompt, her daily AI diary, her AI...

  24. Making $$$ selling to AI Agents

    In this solo episode I break down Cloudflare's AI agent announcement in plain English and explain why I see it as the new business model for the internet. I walk through AI crawl control, pay per crawl, the monetization gateway, and the x402 payment rail, and I show how a single request turns…

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  25. These AI Marketing Agents Get You Customers

    I bring Cody Schneider back on the show to build two marketing agents end to end, live. The first one monitors LinkedIn posts from creators in your category, scrapes everyone who engages, waterfalls those profiles into emails and phone numbers, and then runs cold email and LinkedIn DMs with an...

  26. Graph Engineering Clearly Explained

    I go solo on this one to break down graph engineering, the term I keep seeing go viral on X. I define it in plain English: prompt engineering is how you ask AI a better question, context engineering is how you give AI better information, and graph engineering is how you design the work around the...

  27. Jack Dorsey's Buzz: The New Hermes Agent?

    I sit down with Vinny for a live tour of Buzz, an open source, agent-native chat app from Block built on an open protocol. Vinny makes the case that openness is the real story here: agents arrive as first-class teammates, the harness underneath each agent swaps freely between Claude Code, Codex,...

  28. How I use Claude Code + MCPs to run my marketing

    Cody Schneider is back on the podcast, and I ask him to lay out what a real marketing agent looks like once you get past the hype. He draws a hard line: an agent owns unified business data, runs on a cadence, and improves from the results it reads back. We use one concrete business as the sandbox…

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  29. Most Valuable Skill of 2026: Managing AI Agents

    I welcome Ryan Carson back to the show to turn anyone into a world-class agent operator. Ryan spent 25 years founding companies, scaled Treehouse to around 110 employees and a million learners, and now runs Untangle, an AI divorce agent for family law firms, as a team of one while his revenue...

  30. FDE: The $1M/Year AI Job Explained

    I sit down with Vas from Varick Agents to map out exactly how to break into AI forward deployed engineering — and how to grow into a sharper FDE — in thirty days. We start from a single premise: every company can now buy the same frontier intelligence, so the real advantage moves to deployment.…

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  31. The $1,000/hour Solo AI business (Full Course)

    In this episode I sit down with Corey Ganim to unpack what he calls the simplest way to earn money with AI in 2026: a $999 AI Tools Assessment for small business owners. Corey lays out his entire four-phase system, from a probing discovery call through an AI-assisted analysis in Claude, a...

  32. Making $$$ with Loop Engineering

    I sit down with Elie Steinbock to unpack loop engineering and how to run a business on loops. We start with the roots of the idea in the lean startup and Toyota's manufacturing, then move into practical, copy-ready workflows for SEO, Facebook ads, and product feedback. Elie walks through a live...

  33. Grok 4.5 is a bigger deal than Fable

    In this episode I bring Nick Vasilescu, co-founder of Orgo, back on the show to unpack the buzz around Grok 4.5. Nick makes the case for treating Grok 4.5 as a genuine AI co-founder inside harnesses like Hermes and OpenClaw, and he proves it live: spinning up cloud computers, wiring in tools, and...

  34. We Tested OpenAI's GPT 5.6 for a Month

    In this episode I sit down with Dan Shipper to see how he runs his work and personal life on OpenAI's Codex Desktop with the 5.6 model. He walks through his card-based email setup, daily feeds for his company and Slack, and the in-app browser that lets his agent collaborate with him inside tools...

  35. AI Agents are the new SaaS

    In this solo episode I lay out why I believe building agents is the new SaaS: software is shifting from helping you do the work to doing the work with you. I walk through a full playbook — find a niche, pick a workflow with a paycheck attached, shadow the human, spec the agent, build the minimum...

  36. “Learn AI” Is Bad Advice. Learn These Instead

    In this solo episode, I lay out the six skills I believe stay valuable as AI grows more capable. I chose these six because each one is open to anyone, each one starts this weekend, and each one rises in value as AI improves. I walk through agents and local models, distribution, robotics…

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  37. GLM 5.2 Clearly Explained (and how to set it up)

    In this episode I sit down with Amir to get tactical about running local AI models as part of a daily workflow. We center on GLM 5.2 from ZAI, how it stacks up against frontier models like Opus 4.8, and how a fusion approach lets you sequence a heavy thinking model with a lighter execution model...

  38. Making $$$ with IOS apps

    In this episode I sit down with George Lampropoulos, a 19-year-old founder who turns AI-built mobile apps into real revenue. George walks through his framework for reaching $10K a month—roughly $333 a day—starting with a simple, sellable idea you actually care about and ending with a distribution...

  39. Claude Fable 5 is BANNED. What to do?

    In this solo episode, I walk through the implications of the ban of Claude Fable 5 — the most powerful model on the planet and the one I planned to build with — after the US government sent Anthropic a letter. I make the case for local AI by walking through the benefits: intelligence that lives…

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  40. You are using Claude Fable 5 wrong

    Get my Fable 5 prompt pack: https://startup-ideas-pod.link/fable5-prompt-pack In this episode I break down how to get the most out of Fable 5, the most powerful model I've ever used. I move past the benchmarks and go straight into tactical use cases, copy-and-paste prompts, and startup ideas you...

  41. What are Agentic Loops?

    S/o Coderabbit for sponsoring today’s vid: https://startup-ideas-pod.link/code-rabbit On this episode I sit down with Professor Ras Mic to break down agentic loops. We define what a loop is, explain why well-known builders like Boris and Peter swear by them, and stay honest about who they truly...

  42. Become AI Native in less than 60 mins

    Become an AI Native Organization: https://startup-ideas-pod.link/ai-native-org In this episode I sit down with Theo to unpack what becoming AI native truly means. We define an AI native org as people managing agents, agents reading and writing to the company, and the company growing smarter over...

  43. Hermes Agent App Clearly Explained (and how to use it)

    In this episode, I sit down with Alex Finn for a full, screen-shared walkthrough of Hermes Desktop, the new desktop home for the Hermes AI agent. I open with a clear challenge: by the end, sell me on installing Hermes Desktop, show me real ways to make money and stay productive, and explain his...

  44. Codex Sites Clearly Explained (and how to use it)

    In this solo episode I walk through Codex Sites end to end, building a real internal tool live so you can copy the exact workflow. I open by comparing Codex Sites with one-prompt tools like Replit and Lovable, then construct a Startup Ideas OS board in six prompts. Along the way I cover memory…

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  45. The Next $100B Market: Selling To AI Agents

    In this solo episode, I break down the shift from a human-first internet to an agent-first one, where AI agents become the customers that discover, evaluate, pay, and recommend. I map the agent buying journey and the new infrastructure agents need: identity, tools, an inbox, memory, a wallet, and...

  46. Google's Biggest AI Announcements (I Was There)

    Live from Google I/O, I sit down with Logan Kilpatrick from the Google DeepMind team to unpack everything Google just announced and what it means for founders, developers, and anyone trying to build with AI right now. We dig into Gemini 3.5 Flash, the new Gemini Omni world model, the expanded...

  47. 9 Huge Startup Opportunities in the AI Boom

    I sit down with my friend Jonathan Courtney, a.k.a. Jicecream, to dig into the 9 biggest startup opportunities I see right now across B2C, AI, mobile, and IRL. We each pick ideas, trade reactions, and pressure-test them live. The conversation ranges from agent-first "action apps" to elder tech,...

  48. Andrew Wilkinson: AI Agents run my business and life

    If you want more workflows and tactics to build a business with AI, check out this free workshop: https://www.ideabrowser.com/workshop I sit down with Andrew Wilkinson and we go deep on how he's restructured his work, his health, and his family office around AI agents. Andrew walks me through…

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  49. The $1M+ Solo AI Agent Business (Full Course)

    Nick agreed to personally set up your Orgo in a 15 min call: https://startup-ideas-pod.link/orgo_ai I sit down with Nick from Orgo to break down exactly how to run a one-person AI agent business that can realistically clear a few million dollars a year. Nick walks through the offer, the verticals...

  50. 7 tiny AI agent ideas I built with Genspark Claw

    Get started building your tiny AI Agent business with Genspark Claw: https://www.genspark.ai/?utm_source=po&utm_campaign=GregIsenberg In this solo episode, I share seven tiny, cash-flowing startup ideas you can build with AI in just a few prompts. I walk through how to use Genspark Claw…

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ABOUT THIS SHOW

Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out.

For more startup ideas, we created a database of 30+ startup ideas you can take at https://gregisenberg.com/30startupideas

HOSTED BY

Greg Isenberg

Frequently Asked Questions

How many episodes does The Startup Ideas Podcast have?

The Startup Ideas Podcast currently has 386 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

What is The Startup Ideas Podcast about?

Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out. For more startup ideas, we...

How often does The Startup Ideas Podcast release new episodes?

The Startup Ideas Podcast publishes regularly with 386 episodes available. Check the episode list for the typical release schedule.

Where can I listen to The Startup Ideas Podcast?

You can listen to The Startup Ideas Podcast on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.

Who hosts The Startup Ideas Podcast?

The Startup Ideas Podcast is created and hosted by Greg Isenberg.
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