PODCAST · health
Transformational Pediatrics
by Children’s Mercy Kansas City
Transformational Pediatrics features interviews with physicians and researchers at Children’s Mercy Kansas City who are transforming pediatric care through genomic medicine, personalized therapeutics, health services and outcomes research, and innovations in health care delivery.
Episodes
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Could Gene Therapy Cure My Child's Sickle Cell Disease?
Could gene therapy cure your child's sickle cell disease? Shabnam Arsiwala, MD, Director, Sickle Cell Disease Program at Children's Mercy - Transformational Pediatrics, explains how gene and cell therapies target the underlying genetic mutation rather than only treating symptoms. Learn what…
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From Diagnosis to Thriving: Inside CDH Care
In this episode, Dr. Ekta Patel and Dr. Devon O'Brien from Children's Mercy discuss the intricacies of congenital diaphragmatic hernia (CDH) and why it can be overwhelming for families. They delve into prenatal imaging, potential outcomes, and the multidisciplinary approach to care. Tune in to...
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Understanding Pediatric STEMI: What Makes it Different?
Explore why treating pediatric STEMI is not like treating adults. This podcast discusses clinical presentations, diagnostic challenges, and the critical role of congenital heart disease. Delve into the findings from a decade-long study that reshaped the management strategies for children…
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From Friction to Focus: How Children’s Mercy Reengineered Nursing Workflows with Helen
Children’s Mercy set out to solve a persistent problem in hospital care: nurses spending too much time on non‑clinical tasks. In this episode, CEO Alejandro Quiroga, MD, MBA, shares how the Helen concierge ecosystem is returning meaningful time to nurses, reducing interruptions, and improving...
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Revolutionizing Pediatric Imaging: The Benefits of Flash Scanners
In this episode, Dr. Sarah Guevara hosts Dr. Sanket Shah and Dr. Erin Opfer from Children's Mercy to discuss how the groundbreaking flash scanner technology is transforming pediatric imaging. Discover the advantages of reduced sedation and lower radiation exposure, and why this innovative…
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Faster Answers, Brighter Futures: How Children’s Mercy Is Transforming Genetic Diagnosis
Children’s Mercy is transforming pediatric genetic diagnosis with a single, advanced sequencing test. Learn how this breakthrough is delivering faster answers, fewer tests, and new hope for families facing rare diseases.
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Transforming Pediatric Cardiology with 3D Modeling
Join Dr. Anmol Goyal as he explains the educational power of 3D modeling in explaining complex heart conditions. This episode highlights how visual tools help families understand diagnoses and surgical procedures, making complex medical terms accessible to everyone. Learn more about Anmol Goyal,...
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Histiocytosis Overview and Research
J. Allyson Hays, MD, discusses the rare disease histiocytosis, how it presents in pediatric cases, how Children's Mercy treats it and more. Learn more about Allyson Hays, MD
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The Use of Virtual Reality in Pediatric Surgery
Mark Ryan, MD, MSPH, FACS, discusses the use of virtual reality and 3D imaging in pediatric surgery, and the impact it has on planning, outcomes and the future of pediatric procedures.
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Navigating Kidney Transplants: The Adolescent Journey
Discover the unique challenges faced by adolescent kidney transplant recipients and their families in this deep dive into patient-centered assessments. Host Dr. Mike and pediatric nephrologist Dr. Judith Van Sickle discuss barriers to medical adherence and the importance of a supportive network…
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Unexpected Findings in Study of Gene Mutations for Pediatric Cancer Patients
Tomoo Iwakuma, MD, PhD, discusses recent research findings around his studies of the p53 gene.
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Optical Genome Mapping
Children’s Mercy Kansas City is the first pediatric hospital in the U.S. to clinically launch Optical Genome Mapping (OGM), an advanced digitized technology that enhances the detection of genetic abnormalities. Dr. John Herriges discusses what this means for pediatric care and what's to come.
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Expanding Access to Genetic Testing to Rural Populations
Ana Cohen, PhD, discusses Children's Mercy's cutting edge genetic testing, and how they're improving access by expanding research to rural communities.
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Provider Burnout and Prioritizing Wellbeing
Stephanie Burrus, DO, discusses physician burnout, and how Children's Mercy Kansas City's Center for Wellbeing is addressing it at their institution.
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How We Heal Little Hearts: The Piccolo Procedure Explained
The Piccolo device is an innovative and minimally invasive way to close the Patent ductus arteriosus (PDA) in pediatrics. Dr. Rockefeller talks about how the Piccolo came to fruition, the benefits, and what else is on the horizon for the PDA closure world.
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Updated Dermatology Guidelines and Use of Bactrim
Bactrim is a commonly prescribed antibiotic used to treat a variety of conditions, including urinary tract infections, acne and skin and soft tissue infections. The American Academy of Dermatology recently revised its guidelines discouraging the use of Bactrim to treat acne based on research...
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Genomic Answers for Kids Expands Sequencing to Clinical Setting
Children’s Mercy Kansas City, one of the nation’s leading independent pediatric health organizations, announced it is the first health care system to use 5-base HiFi sequencing, the world’s most-advanced genomic sequencing technology from PacBio, in the clinical setting to accelerate diagnoses…
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Precision Medicine in Pediatrics: Genetic Testing for Children with Cancer
To accelerate precision medicine for pediatric oncology, Children’s Mercy Kansas City, together with its Research Institute (CMRI), pioneered a new whole-exome-sequencing-based genetic test for all children diagnosed with cancer. While many pediatric research institutions in the country conduct...
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Navigating Pediatric Fontan-Associated Liver Disease
Incredible advances in the care of patients born with single-ventricle heart disease have led to significantly better quality of life and survival. Complex surgical palliation culminating in the Fontan procedure is effective and can allow patients to grow and develop similar to their peers....
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Population Health Management and Pediatric Type 1 Diabetes
In this episode, Dr. Mark Clements leads a discussion focusing on population health management and pediatric type 1 diabetes.
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Data Science: Informing Better Health Care Decisions
Data science -- often discussed with terms like artificial intelligence, machine learning, big data, data goverernance -- has the potential to transform every aspect of health care, from the patient experience to how, when and where care is provided, and improving outcomes. In this…
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Professional Coaching in Medicine and Health Care
The health care sector has begun to embrace coaching to promote resilience and innovation during a time of massive disruption while also cultivating healthier workplace cultures. In this podcast, Alyssa Stephany, MD, Director of the Physician Leadership Center at Children's Mercy Kansas City…
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Health and Poverty of Rural Children
Nearly 1 in 5 children in the United States live in rural areas. Rural children experience health and health care disparities compared to their urban peers and represent a unique and vulnerable pediatric patient population. Important disparities exist in all-cause mortality, suicide,...
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Health Care Informatics
What is informatics and why is it important in health care? Listen as Jill Westcott, MD, MS, FACOG, Physician Informaticist for the Fetal Health Center at Children's Mercy, shares her expertise on the topic and how informatics is improving patient outcomes in fetal health.
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Genomic Answers for Kids Establishes New Paradigm in Rare Disease Research
The Children’s Mercy Research Institute® is undertaking a research initiative to build a first-of-its-kind pediatric data repository to facilitate the search for answers and novel treatments for pediatric genetic conditions. Our goal is to collect genomic data and health information for 30,000...
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Transforming Pediatric Research
How do we create a healthier future for children? The Children's Mercy Research Institute with a core focus on genomics, personalized therapeutics, population health, health care innovation and bioethics is positioned to fundamentally transform pediatric research and create a world of well-being...
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Pediatric Hemodialysis and Advances in Infection Prevention and Vascular Preservation
To reduce the risk of complications related to hemodialysis, the Children’s Mercy Kansas City Division of Nephrology has implemented several strategies. Listen as Dr. Bradley Warady shares how the institution of standardized infection prevention practices has resulted in more than 1,200…
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Achieving Transplant Excellence Through Personalized Medicine
Children’s Mercy Kansas City is recognized as one of the top 10 nephrology programs in the nation by U.S. News & World Report, and the kidney transplant program has incorporated a number of innovative practices into their management plan that are designed to enhance patient outcomes. Join us as…
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Impact of Race & Ethnicity on Responses to Folic Acid Dosing
Devika Maulik MD shares her translational research as it relates to folic acid and different responses to dosing among women of various races and ethnicities. She is using the information gathered to create recommended guidelines for folic acid dosing. She discusses current literature on this...
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Pediatric Recurrent Intentional Foreign Body Ingestion: Case Series and Review of the Literature
Dr. Christina Low Kapalu discusses cases and literature surrounding pediatric recurrent intentional foreign body ingestion.
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Variations in Morning Serum Cortisol Levels Based on Sex and Pubertal Status
Dr. Sarah Tsai discusses his recent findings from his study surround serum morning cortisol levels.
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Twin to Twin Transfusion Syndrome: Algorithm for Diagnosing and Treating
Dr. Emanuel "Mike" Vlastos discusses the algorithm for diagnosing and trading twin to twin transfusion syndrome.
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Improved Outcomes for Liver Transplantation with Biliary Atresia
Dr. James Daniel discusses improved outcomes for liver transplantation with Biliary Atresia.
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Clinical Characteristics of Fractures in Pediatric Patients Exposed to PPIs
Dr. Nathan Fleishman discusses the clinical characteristics of fractures in pediatric patients exposed to PPIs.
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Pediatric Provider Well-Being and the COVID-19 Pandemic
The COVID-19 pandemic has created an unprecedented work environment for pediatricians and pediatric subspecialists. How we practice medicine has been dramatically changed. When discussing physical precautions such as PPE and social distancing, provider mental well-being also should be a part of…
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Preventing Type 2 Diabetes
Dr. Kelsee Halpin discusses Endocrinology and Diabetes.
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Bariatric Surgery
Childhood Obesity continues to be on the rise and causes serious health consequences. In this podcast, Dr. Jason Fraser discusses the Bariatric Surgery program at Children's Mercy. We learn who is a candidate for bariatric surgery, the requirements for surgery, why Children's Mercy decided to…
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Polycystic Ovary Syndrome: Current Concepts for A Complex Condition
Dr. Tania Burgert discusses Polycystic Ovary Syndrome (PCOS) and the current ideas surrounding a complex condition.
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How the Cardiac High Acuity Monitoring Program (CHAMP) is Helping Change Lives
CHAMP (Cardiac High Acuity Monitoring Program) is a multi-disciplinary based team that has been designed to meet the needs of the most complex cardiac population with single ventricle heart disease. The program closely monitors patients with single ventricle heart disease between the critical…
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CKiD Expansion
The CKiD study was recently approved for an additional five years and $4.7 million of funding, making 20 consecutive years of funding. Historically, when participants developed end-stage disease, they left the study. The next phase of study will focus on the entire spectrum of the disease…
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Targeted Therapy to Reduce Relapse of Pediatric Leukemia
Patients that have residual leukemia stem cells after chemotherapy and other treatments have substantially higher risk for relapse. Survival rates for relapsed leukemia are very poor. Even when patients survive long-term, the very toxic anti-cancer treatments are escalated in treating relapsed...
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Identifying Novel Drug Treatment Options for Pediatric Osteosarcoma
Osteosarcoma is highly metastatic and drug-resistant cancer. The survival rate for metastatic osteosarcoma remains less than 20 percent for the last 40 years. Tomoo Iwakuma, MD, PhD, is leading research focused on the elucidation of mechanisms underlying osteosarcoma progression and the discovery...
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Management and Treatment for Peutz-Jeghers Syndrome
Peutz-jeghers syndrome (PJS) is an inherited syndrome, characterized by the development of gastrointestinal polyps and characteristic mucocutaneous freckling. Individuals that present with PJS tend to have polyps often in their small intestine as well as their stomach and large intestine.…
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Getting in Front of Type 2 Diabetes
Type 2 diabetes was commonly associated with the adult population. This diagnosis was even referenced as adult-onset diabetes but in recent years type 2 diabetes in children is on the rise. Although researchers aren’t clear as to why some children develop type 2 diabetes there are some causes…
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Is There a Role for Fecal Transplant in IBD?
Can an effective treatment for medically refractive Crohn’s disease be found in the gastrointestinal tract itself? Dr. Alka Goyal with Children’s Mercy Kansas City is exploring the role of fecal transplant as a rescue therapy for patients whose inflammatory bowel disease has not responded to...
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Tourette Syndrome: Using an Evidence-based Algorithm to Guide Treatment
As an expert in the treatment of Tourette Syndrome (TS), recently, Dr. Coffman was asked to author an article on the pharmacological treatment of Tourette Syndrome. In collaboration with Dr. Quezada, the paper was published in CNS Drugs Journal, focusing on current approaches and new developments...
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Precision Therapeutics in the NICU
Neonatal pharmacotherapy is a field ripe with opportunity. Efficacy and toxicity is unpredictable and varies greatly for many drug classes commonly used. Weight-based dosing continues to be the standard of care as individualized drug markers are lacking. To better understand variability in drug...
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Cancer Genomics: Finding Answers Through Data and DNA
Approximately 10 to 15 percent of childhood cancer cases are due to a genetic predisposition. Children’s Mercy Kansas City is searching within the genetic code to not only identify genes that may lead to cancer, but to find answers in how to better treat or cure pediatric cancer. Erin Guest, MD,...
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Mitigating Hyperfiltration-Mediated Kidney Injury
Thanks to the research being done in CKid, we know that children diagnosed with chronic kidney disease progress over time to dialysis and transplantation. That makes it very important to address therapies which can mitigate the progression of chronic kidney disease. Joining the show today is…
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The Decision to Withhold Life-Sustaining Medical Treatment for Children
In pediatrics care most often supports life-sustaining treatment to promote the best interests of the child. But in some circumstances (after weighing the balance of benefits and burdens of a range of treatment choices) continuing life-sustaining treatment is decided to no longer be in the…
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ABOUT THIS SHOW
Transformational Pediatrics features interviews with physicians and researchers at Children’s Mercy Kansas City who are transforming pediatric care through genomic medicine, personalized therapeutics, health services and outcomes research, and innovations in health care delivery.
HOSTED BY
Children’s Mercy Kansas City
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