TT HealthWatch
by Dr. Richard Lange and Elizabeth Tracey
Stay up-to-date with the latest research in medicine and science with TT HealthWatch. This 10-minute podcast is hosted by Richard Lange, M.D., M.B.A., president of Texas Tech University Health Sciences Center El Paso and dean of the Paul L. Foster School of Medicine, and Elizabeth Tracey, M.S., Baltimore-based medical journalist. Each week, Richard and Elizabeth explore recent peer-reviewed studies and breaking medical news, offering a Texas Tech perspective on the latest developments in health care.
Episodes
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Colorectal cancer, AI authorization, T cells, ALS, and T1D
Program notes: 0:41 Subtypes of T1D in adults 1:41 Three distinct subtypes 2:41 Not investigated before? 3:41 Reduced islet cell autoimmunity 4:14 Early onset CRC 5:15 Sidedness in body 6:16 Increased stromal to epithelial ratio 6:50 AI enabled prior authorization 7:50 Was a change in frequency…
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Achilles tendinitis, breast cancer, cardiac stent placement, and depression medication
Program notes: 0:45 Imaging for cardiac stent placement 1:45 12 month target vessel failure 2:38 Treatment resistant depression and psychedelic medicine 3:38 Three dosages and psychological support 4:38 Adverse events same among all groups 5:38 Will it last longer than 60 days? 6:36 Need to…
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Pregnancy and kidney donation, AI to manage epilepsy, targeting KRAS, and glucose monitoring
Program notes: 0:35 Continuous glucose monitoring in Type 2 diabetes not using insulin 1:40 Decreased HbA1c 2:35 Already shown to be beneficial in those using insulin 3:30 Cancer vaccines 4:30 Disease-free survival endpoint 5:32 If T-cell population increased 6:30 Pregnancy outcomes in women who...
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Coronary revascularization, AI clinician use, infant outcomes in labor, and donor hearts
Program notes: 0:40 Clinician use of AI clinically 1:40 703,000 active monthly users 2:40 How helpful is this? 3:40 More up to date 3:50 Prognostic model to estimate fetal compromise 4:50 Data from singleton births 5:50 Fit4labour model 6:50 Could be used 8 hours before a problem 7:11 Drug coated...
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Adult ADHD, hospital closures, advance care planning, and HPV vaccination
Program notes: 0:36 HPV vaccines and pregnancy outcomes 1:36 600,000+ births 2:36 What is the mechanism? 3:30 Adult ADHD 4:30 May see underperformance 5:30 Almost always methylphenidate or amphetamine 6:30 Public health significance 7:01 Hospital closures in the U.S. 8:01 Safety net, non-teaching...
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Liver disease, HT and thromboembolic risk, cancer screenings, and septic shock
Program notes: 0:40 Lean metabolic associated liver disease 1:40 Biopsy confirmed MASLD 2:40 Elastography for diagnosis 3:41 Liver transplant often needed 4:04 HT and thromboembolic disease 5:04 VTE, ischemic stroke and MI 6:04 Oral estrogen increased risk 7:07 LIquid cancer biopsy impact 8:07…
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Breast Cancer, Asthma and COPD, Statins for Seniors and Improving Primary Care for Chronic Conditions
Program notes: 0:33 Statins for older people without CVD 1:34 Followed for six years 2:34 Aged to 70 without CVD 3:00 Improving primary care for folks with chronic conditions 4:00 70,000 respondents 5:00 Long term relationship with a primary care provider 6:00 Continuity and coordination can be...
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Exercise for Cancer Patients, Colonoscopy Surveillance, Vaccinations Save Lives, Metabolic Acidosis
Program notes: 0:40 Structured exercise after cancer 1:40 Moderate evidence 2:40 Improves overall survival 3:41 Improves drug penetration 4:00 Colonoscopy intervals after polyp removal 5:00 Five-year cumulative incidence same as three years 6:03 Covid vaccination and immune checkpoint therapy…
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Strokes, Crohn’s top-down therapy, oxygen for preterm infants, maternal diet
Program notes: 0:37 New stroke therapy 1:37 Use of IV for 10 days after stroke 2:37 Present late after a stroke 3:39 Long term outcomes of top-down therapy in Crohn's 4:40 Outcomes up to five years 5:40 Early TNF use from diagnosis improves outcomes 6:42 No real downside 7:38 How much oxygen for...
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COPD, Respiratory Virus Vaccines, Preeclampsia, and Cardiomyopathy
Program notes: 0:33 Vaccines for RSV, flu, and Covid 1:35 Studies available right now 2:33 Reduction of hospital encounters for infants 3:33 Maternal vaccination for RSV 4:34 Gene silencing therapy for cardiomyopathy 5:35 Decreased primary outcome about 20% 6:35 Should we be screening? 7:06 A new...
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PE, Afib, cognitive function, EKG and syncope
Program notes: 0:44 EKG monitoring and syncope 1:45 No difference when monitored 2:45 Why not try monitoring? 3:13 Catheter directed thrombolysis in PE 4:14 Composite of death from any cause 5:14 Assessment for intermediate or high risk 6:16 Treatment not onerous 6:45 Afib ablation versus sham…
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ADHD and CVD, hospice care, CTE and dementia, anemia, cardiac surgery and IV iron
Program notes: 0:37 CTE and dementia in NFL players 1:37 Post mortem CTE presence and stage 2:35 Past look at brains of players who died 3:35 Lesion is perivascular tau 4:34 Warning on repeated head trauma 5:14 IV iron for anemia before cardiac surgery 6:14 Anemic before surgery? 7:17 Hospice in...
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Emergency department, ventilated patients, platelets, and CPR devices
Program notes: 0:35 Devices to do CPR versus manual 1:37 About 60% of U.S. population 2:32 8-9% survive with favorable neurologic status 3:15 Ventilated patients and reduction of mucous secretions 4:15 Duration of ventilation unchanged 5:15 Regulate or expectorate 5:40 Boarding ED patients 6:45...
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High cholesterol, cannabis, dementia, and PMR
Program notes: 0:38 Polymyalgia rheumatica treatment 1:35 Antibody targets interleukin 17a 2:35 Remission started at 12 weeks and was durable to 52 3:11 Cannabis and hyperemesis syndrome 4:11 Cannabis-related ED visits 5:11 Prior to the new coding didn't link 6:05 Gene inhibition of PCSK-9 7:05...
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Caffeine, antihistamines, heart-failure, and e-cigarettes
This week's topics include caffeine's impact on CVD, antihistamines and atopic dermatitis, a community designed diet for heart failure, and e-cigarettes after smoking cessation.
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Alzheimer’s, acute pain, alcohol consumption and pregnancy, and nonalcoholic fatty liver disease
Program notes: 0:44 Novel agent for acute pain 1:44 Post-abdominal surgery and placebo, low and high dose 2:46 Compared to placebo and opioids 3:19 Metabolic associated steatotic liver disease 4:19 Imaging with two techniques and plasma markers 5:19 Imaging and composite scores for staging 6:21...
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GLP1s and AUD, CVD risk, lipid lowering targets, and status on vaccine for gonorrhea
This week's topics include GLP1s and AUD, impact of CVD risk calculation, meeting lipid lowering targets, and no luck with a vaccine for gonorrhea.
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Continuing dual antiplatelet therapy, Alzheimer's, infections in US hospitals, and algorithms for diagnosing PE
This week's topics include continuing dual antiplatelet therapy after stenting, amyloid depletion in Alzheimer's, infections in US hospitals, and algorithms for diagnosing PE in people with cancer.
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Hip prosthesis, pulmonary fibrosis, respiratory viruses, and GLP-1s
Program notes: 0:40 Online prescribing of GLP1s 1:44 Physician asks a number of questions 2:44 Interaction to approval about five minutes 3:30 Respiratory outbreak mitigation in nursing homes 4:30 Using PCR-based test in the nursing home 5:30 No difference in outbreak number or size 6:35 Avoid...
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Technology to improve stroke outcomes, social media, and clinical management
This week's topics include technology to improve stroke outcomes, adult use of social media and health decisions, impact of social media ban on Australian youth, and an LLM to augment clinical management in a low resource setting.
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TKR patellar resurfacing, CAR-Ts, tranexamic acid, and patient messaging
Program notes: 0:40 Electronic patient messaging 1:40 Not baked into the usual workday 2:40 Managing patient expectations 3:33 Tranexamic acid in noncardiac surgery 4:33 Almost 9,000 patients enrolled 5:30 Does it increase VTE? 6:31 UK attempted 10 years ago 7:00 CAR-T cell outcomes 10 years…
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Brain development in kids, multimorbidity, childhood obesity, and prehabilitation
This week's topics include SES and brain development in kids, lifestyle changes and multimobidity, food labeling and childhood obesity, and prehabilitation in elders.
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CVD risk factors, cognitive decline, insulin price, and factors in IBD
This week's topics include visceral fat and CVD risk factors, delirium and cognitive decline and hospitalization, caps on insulin price, and factors involved with IBD.
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Resistance training, low back pain, cfDNA cancer screening delays, and GLP1s and knee replacement
Program notes: 0:35 Cell-free DNA screening for cancer and diagnosis delays 1:35 Populations-based screening 2:35 24 different companies offer liquid biopsy 3:01 Can we prevent chronic back pain after acute back pain? 4:01 Impact score on chronic back pain 5:01 Real-world setting lacks impact…
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Dual anticoagulation, miscarriage, at home rehab, and weight loss
This week's topics include duration of dual anticoagulation following bypass grafting or stents, how has management of miscarriage changed, at home rehab after an ICU stay, and weight loss for atrial fibrillation.
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PCOS name change, whole blood, antibiotics, and blood markers
Program notes: 0:37 Prehospital resuscitation with whole blood 1:37 Compared with blood components 2:35 Easier to store 3:19 Azithromycin in wheezing kids 4:19 Treated for five days 5:26 Name change from PCOS to PMOS 6:26 Consensus build 7:28 Improved accuracy of pathophysiology 8:30 Adjust…
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Digoxin, thrombectomy, maternal occupation during pregnancy, and exercise
Program notes: 0:36 24 hour ambulatory blood pressure and exercise 1:36 Aerobic, combined and HIT helped 2:36 Some combined with other things known to be beneficial 2:54 Medium sized vessel thrombectomy 3:54 Thrombectomy or medical management 4:54 Carefully selected patients benefit 5:55 About...
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Nonprofit hospital work, GLP-1 use, weight loss drugs, and transcranial stimulation
Program notes: 0:40 Transcranial stimulation for ASD 1:40 Used evoked potential and quick pulses 2:41 Motor cortex associated with speech and language 3:27 A model for benefits from GLP-1 use 4:27 Discern who would be most likely to develop obesity complications 5:27 Target to those more likely…
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UTIs, cancer in young people, knee osteoarthritis, and vaccine uptake
Program notes: 0:35 Factors regarding vaccine uptake 1:35 Adolescents didn't like human to human 2:35 Free vaccines helpful 3:00 Treating osteoarthritis of the knee 4:00 Dose response to reduce pain score 5:00 Does it elicit an immune response 5:35 Factors in increasing cancer rates in younger...
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Polypill, bloodstream infections, Paxlovid, and treating acute sinusitis
Program notes: 0:30 Controlling HTN after intracerebral hemorrhage 1:30 Triple pill or placebo 2:30 Only effective treatment is lowering blood pressure 3:32 Serum creatinine levels 4:15 Is there a role for Paxlovid? 5:15 Did not reduce hospitalization or death 6:10 Fast antimicrobial…
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PPIs, kidney function equations, DVT, and timing of exercise
Program notes: 0:34 Chronotrope type and timing of exercise 1:36 Sedentary adults and morning or evening type 2:36 Acting as your own control 3:10 Stenting for post thrombotic syndrome 4:10 Severity lower with endovascular therapy 5:10 Patent in 2/3 at six months 6:10 Very diverse patient...
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Levothyroxine, drug coupons, low cholesterol and heart disease, and hypertension
Program notes: 0:36 How low should cholesterol be targeted in secondary prevention? 1:40 33% reduction with target to 55 2:36 Able to do it with statin and other drugs 3:03 Deprescribing levothyroxine 4:06 Were able to discontinue in many 5:05 Thyroid not as responsive with aging 6:05 Barriers to...
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Dulaglutide or Tirzepatide, hepatitis C treatment, long COVID-19 treatment, and biopharma updates
Program notes: 0:38 Migrating biopharma industry 1:36 Early stage development 2:36 Need to replicate studies 3:23 Treatment for fatigue from long Covid 4:25 Fluvoxamine or metformin 5:25 Only fluvoxamine helped 6:25 Only for fatigue 6:35 How treatments for hepatitis C have been used 7:36 Number…
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Cooking and dementia, asymptomatic aortic stenosis, pediatric sepsis, and high-dose versus standard-dose flu vaccines
Program notes: 0:36 High versus standard-dose flu vaccines in older people 1:36 Cardiovascular outcomes 2:26 Also in those with previous CVD 3:10 Cooking and dementia risk 4:10 Cooking frequency and skills assessment 5:10 Tasks relative to preparing a meal at home 6:10 Encourage home cooking 6:30...
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Diet and brain structure, colorectal cancer screenings, cholesterol guidelines, and glaucoma screenings
Program notes: 0:35 New cholesterol lowering guidelines 1:35 Risk scores new 2:35 Mainstay is behavioral change 3:35 For those with a longer view 4:00 AI based glaucoma screening in primary care settings 5:00 Either AI or pressure 6:00 Fundus photograph and intraocular pressure 7:00 Sensitivity…
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Sleep in adolescents, GLP1s, predicting Alzheimer's, and cancer screenings
Program notes: 0:44 Adolescents and sleep duration 1:44 Very short sleep duration 2:44 Increased among all subgroups 3:45 Structural factors more important 4:45 Moving school start later 5:02 GLP1 agonists and various patient characteristics 6:02 Greater weight loss in women 7:06 A blood test to...
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COVID-19 vax and preeclampsia, HIV injections, monkeypox, and HPV testing
Program notes: 0:37 HIV treatment monthly injections 1:37 Long acting and effective 2:37 Some didn't come for monthly injections 3:16 COVID-19 vaccination and preeclampsia rate 4:16 In two successive cohorts during pandemic 5:16 Pre-existing morbidity 58% reduction 6:15 COVID-19 cytokine storm?...
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Accountable care organizations, HT and mortality, accessibility of dialysis in the U.S., and cannabis use
Program notes: 0:37 Hormone therapy and mortality 1:37 Those who used versus those unexposed 2:35 Different types of HT 3:32 Adolescent cannabis use and mental illness 4:32 Screened in physician office 5:32 Action at societal and government levels 6:00 Access to dialysis facilities and SES 7:01…
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Statin therapy, shoulder MRIs, planetary health diet, and food prescriptions
Program notes: 0:35 Diabetes and food prescriptions 1:35 Got a food card to purchase nutritious foods 2:32 More than half didn't use it or used it less than 60% 3:00 Adequacy of a planetary health diet 4:00 Micronutrient intake and biomarkers 5:00 Doesn't seem to compromise long-term health 6:12...
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Removing fallopian tubes to prevent ovarian cancer, and using the EHR to deprescribe risky medicines
Program notes: 0:38 Removal of fallopian tubes to prevent ovarian ca 1:43 129 studies included 2:43 Women who no longer desire pregnancy 3:40 Technically feasible 4:30 New oral PCSK9 inhibitor 5:35 Think it's a slam dunk 6:08 EHR helping deprescribing in older adults 7:08 Two sequential EHR...
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Heart transplant after circulatory death, LLM to ease specialist care transition, treating gout to reduce risk of CVD, and PCOS and arrhythmia
Program notes: 0:50 Rapid recovery of hearts for transplant after circulatory death 1:50 Total ischemic time longer than 4 hours 2:50 Typically reanimate 3:50 Expanded to donors 40 years of age 4:55 Do women with PCOS have increased risk for arrhythmia 5:55 Incidence arrhythmia in these women...
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Stress and race, tobacco companies and social media, statins and pregnancy, and parents’ firearm injuries impact on kids
Program notes: 0:45 Impact on kids of parental firearm injury or death 1:46 Eight additional psychiatric diagnoses per 100,000 2:39 Lifetime stress, inflammation and racial disparities in mortality 3:40 Black individuals shorter survival 4:40 Precise number is difficult to understand 5:40...
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Weight regain after medications for weight loss, benefits of exercising, heart failure and detecting measles
Program notes: 0:40 Two MMWR reports on wastewater to detect measles 1:40 Subsequent detection after early identification 2:40 Watch worldwide transition 3:15 Weight regain after medication for weight management 4:16 Cardiometabolic risk factors return in just over a year 5:16 Willingness to use...
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Vaccination in children, CNS medicines in older adults, FDA and mifepristone, and skilled nursing facilities trends
Program notes: 0:38 Childhood vaccinations nationally 1:30 Across 45 states and DC 2:34 Level of vaccine protection 3:34 Professional societies stepping in 3:51 Skilled nursing facilities 4:51 Estimated operating capacity 5:51 Backups into hospitals 6:51 Staffing not returned to pre-pandemic…
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Screen time and anxiety, global pain levels, d-dimer and DVT, and tertiary patients
Program notes: 0:35 Global pain burden 1:35 Prevalence increased in 15 countries 2:35 Higher prevalence in older people but not consequence of aging 3:02 Tertiary patents 4:03 in the Orange Book 5:05 Prolonged patent protection and higher prices 6:07 Focused on high revenue products 6:50…
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Back pain, private equity and IVF clinics, EKGs and liver disease, and lay health workers
Program notes: 0:40 IVF clinics and private equity 1:40 Provide over 54% of all IVF cycles in U.S. 2:41 Perhaps a more positive result 3:30 EKGs and liver cirrhosis 4:30 New diagnosis of advanced liver disease 5:30 Most physicians didn't follow up 6:18 Management of acute back pain 7:18 Did it...
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Lung cancer screenings, saturated fats, and antiviral use
Program notes: 0:40 Saturated fat and CVD 1:40 When it was reduced in diet only helped in those with high risk 2:40 Obesity, diabetes and metabolic syndrome also important 3:30 Diagnostic follow up after lung CT 4:30 Less intensive than recommended in non-Hispanic blacks 5:31 Herpes antiviral and...
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COVID vaccinations, breast density, and complex pain syndrome
Program notes: 0:37 Breast density knowledge outcomes 1:37 Breast density notification and education 2:37 Can't assess the import individually 3:30 CV outcomes with tirzepatide 4:30 HbA1c 8.4 5:30 GLP-1s have many benefits 6:30 No difference in adverse events 7:10 Covid vaccination in pregnancy...
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Pain, preeclampsia, AI and stroke, and rotator cuff surgery
Program notes: 0:35 Should surgery efficacy 1:30 10-year follow of ASD surgery 2:30 Exercise does relieve pain 3:00 Association of pain with intrinsic capacity and inflammation 4:00 Domains including locomotion and others 5:01 Pain impacts a number of capacities 6:01 Aspirational to figure out…
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Corticosteroids in pregnancy, GLP-1 guidance, tai chi for insomnia, and vaccine updates
Program notes: 0:35 Update on RSV, flu and COVID-19 vaccines 1:35 500 studies included 2:35 Rare myocarditis 3:35 Flu vaccine in older adults 4:30 Tai chi or CBT-I for chronic insomnia 5:30 Trained in one or the other 6:30 Inexpensive and accessible 7:30 $150 billion cost of chronic insomnia 7:45...
About this show
Stay up-to-date with the latest research in medicine and science with TT HealthWatch. This 10-minute podcast is hosted by Richard Lange, M.D., M.B.A., president of Texas Tech University Health Sciences Center El Paso and dean of the Paul L. Foster School of Medicine, and Elizabeth Tracey, M.S., Baltimore-based medical journalist.
Each week, Richard and Elizabeth explore recent peer-reviewed studies and breaking medical news, offering a Texas Tech perspective on the latest developments in health care.
Hosted by
Dr. Richard Lange and Elizabeth Tracey