Two Onc Docs

This week’s episode will be focusing on Diffuse Large B-Cell Lymphoma (DLBCL). We will go all the important details on this aggressive NHL which can be highly curable. We have some new changes since we last covered this topic in 2022 including a new category 1 option for advanced DLBCL

This week’s episode we are back with our very special guest, friend and colleague Dr Laura Vater joining us to talk about wellness in oncology, and burnout prevention tips.

This week’s episode we have a very special guest, friend and colleague Dr. Laura Vater joining us to talk about one of the biggest transitions in medicine—moving from fellow to attending.Dr Vater is a GI oncologist at IU, writer, and speaker. She focuses on the dignity of patients and clinicians, and strives to keep healthcare human. 

This week’s episode will be focusing on an ASCO 2026 Plenary abstract, SARC 041. SARC041 is the first positive phase 3 randomized controlled trial of a CDK4/6 inhibitor in advanced dedifferentiated liposarcoma (DDLPS), demonstrating that abemaciclib significantly improves progression-free survival compared to placebo. 

Today we are recapping exciting GU data presented at the 2026 ASCO Annual Meeting in bladder cancer, kidney cancer, and prostate cancer.

This week’s episode will be focusing on the 2026 ASCO Plenary that received a standing ovation, the RASolute 302 trial.The RASolute 302 trial is a landmark phase 3 study demonstrating that daraxonrasib doubled overall survival compared to chemotherapy in previously treated (2L) metastatic pancreatic ductal adenocarcinoma (mPDAC).

Today we will be focusing on exciting data to come at the ASCO Annual Meeting in 2026 in Chicago, with a special focus on GU sessions, educational sessions & med ed sessions.

This week’s episode will be focusing on Von Willebrand disease (VWD), a highly testable bleeding disorder. We will go over all the important details on the diagnosis, types of VWD as well as treatment.

Today’s episode is focusing on the highest yield facts about Aplastic Anemia. This will include the mechanism of AA, diagnostic work-up, treatment of AA, and the evolution of clones including PNH.

Today’s episode is focusing on what you need to know regarding metastatic bladder cancer, with 2026 updates. This will include the need to know treatment options and toxicities for metastatic urothelial carcinoma, and also discuss the management of upper tract + variant non-urothelial histology.

Today’s episode is focusing on what you need to know regarding localized bladder cancer, with 2026 updates. This will include the need to know pathology, presentation, diagnostic work-up, staging, and treatment options. 

This week’s episode will be focusing on how we met, the future of the podcast, and why we picked heme/onc. This is a very different style of episode and a special once because this month is our 4 year anniversary of Two Onc Docs! And we will back to our regular programming next week with overdue updates on Bladder Cancer.

We are back with a very special guest Dr. Michael Pishvaian, who is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 3, we discuss supportive care in pancreatic cancer, and exciting trials in this space.

We are back with a very special guest Dr. Michael Pishvaian, who is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 2, we will focus on metastatic pancreatic cancer, 1L treatments, maintenance therapy, targeted therapy + more. 

This week’s episode will be discussing Pancreatic Cancer with a very special guest Dr. Michael Pishvaian. Dr. Pishvaian is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 1, we will focus on risk factors, diagnosis and treatment of localized pancreatic cancer. 

This week’s episode will be focusing on a recap of some of the important data ASCO GU just held in San Francisco end of February. We will go over some topics in prostate, RCC, bladder cancer, and other GU tumors. 

This week’s episode will be focusing on Neuroendocrine Tumors (NET). We will go over all the important details regarding the heterogeneous group of NETs, diagnosis, work-up, treatment, and focus mostly on gastro-entero-pancreatic NETs.

This week’s episode we are back with our special guest & thrombosis expert Dr. Marc Carrier.  In part 2, we discuss additional special considerations like IVC filter indications, and management of VTEs in the setting of thrombocytopenia. We also discuss VTE prevention in patients with cancer, the Khorana score, exciting research to come in this space, and career advice.

This week’s episode will be focusing on a very important topic, with our special guest Dr. Marc Carrier. Dr. Carrier is a Professor in the Faculty of Medicine, and holds a Tier 1 Clinical Research Chair in Venous Thromboembolism and Cancer from the Faculty of Medicine at the University of Ottawa. We discuss the work-up and treatment of VTEs and cancer, including types of anti-coagulation, duration, and special considerations.

This week’s episode we discuss what to look forward to at ASCO GU this week. Held in SF Feb 26-28 in San Francisco. We will go over the program in prostate cancer, kidney cancer, bladder cancer, as well as testicular cancer.

This week’s episode, we are back with our special guest Dr. Ria Kraft, a radiation oncologist and host of Rad Onc Talks. In part 2, we go over important details on duration + fractionation schemes, indications for palliative RT, other indications for RT in metastatic disease, and more.

This week’s episode will be focusing on basics of radiation oncology. We are so excited to welcome a special guest Dr. Ria Kraft, who has a YouTube channel called Rad Onc Talks for radiation oncology education. In part 1, we go over important details on types of radiation, how it works, the patient experience, common side effects and more.

This week’s episode we are so excited to welcome Dr. Chadi Nabhan, who is a hematologist and medical oncologist, author, and host of Healthcare Unfiltered. We discuss why oncology, our career paths, different career paths in hematology and oncology, contract & negotiation considerations, as well as tips to search for a job.

This week’s episode is a new topic! We will be focusing on basics of nutrition in oncology. We are so excited to welcome a very special guest Dr. Krystle Zuniga, who is a board-certified specialist in oncology nutrition. In part 2, we will go over dietary strategies focusing on cancer prevention, and myths around what causes cancer.

This week’s episode is a new topic! We will be focusing on basics of nutrition in oncology. We are so excited to welcome a very special guest Dr. Krystle Zuniga, who is a board-certified specialist in oncology nutrition. In part 1, we will go over information + myths in oncology nutrition including cancer feeds sugar, fiber, estrogen, supplements, fasting, and more.

Happy New Year! This week’s episode will be focusing on 2026 update for Follicular Lymphoma. We will go over the important details on the diagnostic criteria, indications for treatment and types + toxicities of treatment.

This week’s episode will be focusing on an update of a late-breaking abstract presented at ASH 2025 this past week: the Phase 3 BRUIN-CLL 313 trial looking at Pirtobrutinib vs Bendamustine/Rituximab in 1L Chronic Lymphocytic Leukemia (CLL).

This week’s episode will be focusing on gastrointestinal stromal tumors, known as GIST with a 2025 update. We will go over important details on the diagnosis, mutations, and treatment of local and metastatic GISTs.  

This week’s episode is also due for an update since it aired in 2022. Will be focusing on Hodgkin Lymphoma (HL), both classical and nodular lymphocyte-predominant. We will go into important details on the pathology, staging, Deauville scoring, and treatment for early stage/advanced stage as well as relapsed and refractory HL.

Today’s episode is focusing on what you need to know regarding Anal cancer. This was one of our first episodes back in 2022 so it is time for an updated episode! This will include the important details on risk factors, diagnostic work-up, staging and treatment of both localized and metastatic anal cancer.

This week’s episode will be on many exciting updates were announced at ESMO this October in Berlin from Oct 17-21, 2025, especially in bladder cancer, we continue to make such progress! We discuss key trials in NMIBC (POTOMAC), MIBC (KN-905, IMvigor-011), and metastatic urothelial carcinoma (FORAGER-1, DV + Toripalimab).

This week’s episode will be focusing on details of the hematology & oncology board exams, how we prepared the days leading up to our exam, and we cover some highly tested topics in both hematology & oncology. We wish the best of luck to everyone taking their boards this year!

This week’s episode will be focusing on Porphyrias…which is very timely since this week is HALLOWEEN and porphyrias are the diseases many people believe started the vampire legend! 

This week’s episode is part 3 of our breast cancer series, with a 2025 update focusing on metastatic breast cancer systemic therapies, toxicities, and supportive care considerations. 

This week’s episode will be focusing on treatment options for localized breast cancer with 2025 updates. We will go over important details on indications for adjuvant radiation, as well as therapies based on the ER/PR/HER-2 receptor status.

October marks Breast Cancer Awareness Month. We are providing 2025 update for our 3 part breast cancer episodes, in part 1 today we cover an introduction on breast cancer screening, prevention. 

This week’s episode will be focusing on Esophageal and Gastrosophageal Junction (GEJ) Cancer. We will go over important details on the risk factors, diagnosis, and treatment for both localized and metastatic esophageal cancer.

This week’s episode will be focusing on Immune Thrombocytopenia Purpura ( ITP).   We will go all the important details on causes, mechanism, diagnosis and treatment. The last time we covered this topic was in Sept 2022, and this comes up ALL the time in heme consults, and there will definitely be board review questions. It may also be tested on IM boards.

This week’s episode will be an update on Bone Sarcomas. We will go over the important details on diagnosis, staging, subtypes and treatment of a few bone sarcomas. Just like Soft Tissue Sarcomas, these are RARE tumors encompassing 1% of all adult cancers and having multiple subtypes. They are more common in children, and most of our bone sarcoma recommendations that are testable are based on pediatric data.

This week’s episode will be focusing on soft tissue sarcomas. We last recorded this topic in 2023, and well we have some new FDA approvals and updates since then.We will go over the important details on the diagnosis, subtypes and treatment of a few soft tissue sarcomas. These are RARE tumors encompassing 1% of all adult cancers and having multiple subtypes that range from noncancerous tumors such as desmoid tumors to aggressive cancers and everything in between. 

Today’s episode will focus on an update for commonly tested Thrombotic microangiopathies (TMA) such as Thrombotic Thrombocytopenic Purpura (TTP). This will include the high yield facts on mechanism, presentation, diagnostic work-up, and treatment of TTP, and also discuss Hemolytic Uremic Syndrome (HUS), and atypical HUS.

This week’s episode will be focusing on Gastric Adenocarcinoma. We will go over all the important details on risk factors, diagnostic work-up, staging and treatment for both local regional disease and metastatic disease with updates in 2025 since we last covered this topic in 2023.

We are updating another important GYN ONC topic: endometrial (uterine) cancer. We will go over all the important details on the risk factors, presentation, diagnosis, staging & treatment options. We will also cover rare uterine malignancies at the end of the episode.

Today’s episode we will cover 2025 updates for metastatic renal cell carcinoma. We will discuss risk categories, treatment options, and variant histologies. We are so excited to have Dr. Tom Powles and Dr. Brian Rini from the urologic oncology podcast Uromigos sharing their expertise on today's episode as well!

Today’s episode we will cover 2025 updates for localized renal cell carcinoma (RCC) with Dr. Tom Powles and Dr. Brian Rini from the urologic oncology podcast Uromigos! We will discuss risk factors, the presentation, staging, and treatment options. 

This week’s episode will be focusing on Cervical Cancer with some updates since we last released this topic in 2022. We will go over important details on prevention, risk factors, diagnosis & treatment.

This week’s episode is an update on a must-know topics both for new fellows & residents. We will go over clinically important oncologic emergencies including brain metastases, hypercalcemia of malignancy, cord compression and SVC syndrome. 

This week’s episode will be focusing on one of the GI plenary session abstracts presented at the ASCO Annual Meeting 2025,  the MATTERHORN trial: phase 3 durvalumab + FLOT which is 5FU leucovorin, oxaliplatin and docetaxel in resectable gastric or GE junction CA. 

This week’s episode will be focusing on how to prepare for the start of heme/onc fellowship! We will go over some general advice on how to succeed, study tips and resources we used throughout fellowship as well as some tips on how to stay academically productive during training if you are planning for an academic career.

This week’s episode will be focusing on one of the 2025 plenary sessions: SERENA-6, Camizestrant, a novel selective estrogen receptor degrader (SERD) + CDK 4/6i for tx of emergent ESR1 during 1L endocrine-based therapy + ahead of progression in stage 4 HR+/Her-2 negative breast cancer.We discuss the trial design, endpoints, results, safety concerns, and how it fits into current practice.