PODCAST · health
Your Fertility Pharmacist
by Your Fertility Pharmacist—Infertility and Reproductive Medicine, Fertility Medications
The latest fertility research presented by a board-certified clinical pharmacist. For women trying to conceive, this information can help to navigate the science behind the fertility journey.
Episodes
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Fortysomethings, Donor Eggs, and Baby Success
A retrospective cohort study found that maternal age (40-44 vs. 45-49 vs. >49 years) impacts live birth rates using donor oocytes (eggs).
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Preconception Antibiotics and Fertility
Resources Alemu BK, Wang CC, Li L, Zhu Z, Li Q, Wang Y. Effect of preconception antibiotics exposure on female reproductive health and pregnancy outcomes: a systematic review and meta-analysis. EClinicalMedicine. 2024;78:102935. Published 2024 Nov 22. doi:10.1016/j.eclinm.2024.102935 Shao S, Pan…
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Accuracy & Mail-In Semen Kits
A comparison of accuracy between delayed, mail-in semen analysis and fresh, clinic-based samples.
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Fight of the Follitropins: Gonal-F vs. Puregon
This study compared efficacy of two r-FSH medications: follitropin alpha (Gonal-F) vs. follitropin beta (Puregon) on the number of live births cumulatively (CLBR). This was looking at patients 21-45yrs doing fresh embryo transfer after their first IVF or ICSI cycle. Resources Cao JX, Song JY....
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PRP and POR
The most rigorously designed trial (to date) of intraovarian PRP demonstrated no improvements in # of mature oocytes obtained or # of live births versus no injections.
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Letrozole vs. Clomiphene: the OG Study
Resources Bronson R. and Kruljac I, Butorac D, Vrkljan M. and Legro RS, Zhang H; Eunice Kennedy Shriver NICHD Reproductive Medicine Network. Letrozole or clomiphene for infertility in the polycystic ovary syndrome. N Engl J Med. 2014;371(15):1463-1464. doi:10.1056/NEJMc1409550 Centers for Disease...
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COVID Infection after Embryo Transfer
A new study examines the associations between COVID-19 infection with pregnancy and miscarriage rates, looking at the first ten weeks after fresh embryo transfer.
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Liraglutide and Male Reproductive Health
A study compared fertility and sexual markers in obese men with low testosterone and erectile dysfunction who took liraglutide, uFSH + HCG, or testosterone. These men were separated into three groups based on their plans for parenthood; results showed impressive improvements on the GLP-1 agonist...
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Use of a New Oral Drug in Egg Donor Cycles
A recent study compared GnRH antagonists in egg donor ovarian stimulation cycles. The first drug is a newer agent, elagolix (Orilissa), that is taken as a tablet at night. The older drug is an injectable agent called ganirelix (Fyremadel). How did Orilissa stack up in terms of eggs retrieved and...
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Improving Ovarian Function in Obesity with IV FSH
A new trial tested a new way to give FSH to improve ovarian function in obese women without PCOS who are struggling to conceive. Resources Borgert BJ, Bacchus MW, Hernandez AD, Potts SN, Campbell KJ. The availability of gonadotropin therapy from FDA-approved pharmacies for men with hypogonadism…
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Dex + Letrozole for PCOS Ovulation Induction
New study on combining low-dose dexamethasone with letrozole in women with PCOS who failed to ovulate with letrozole alone. This study looked at ovulation, pregnancy, and live birth rates and took place at the Mayo Clinic from 2019 to 2022. Resources Barbieri RL and Ehrmann DA. Diagnosis of...
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Herbal and Supplement Use in Fertility Treatments
Women report their use of herbs and supplements to a fertility clinic that assesses their herb-drug interactions. Resources Friedman J, Sheeder J, Lazorwitz A, Polotsky AJ. Herbal supplement use among reproductive-aged women in an academic infertility practice. F S Rep. 2022;4(1):104-111.…
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Progesterone for Threatened Miscarriage
Does vaginal progesterone prevent miscarriages after early pregnancy bleeding? The research world has yet to agree, but a recently published Australian study (aka "the STOP trial") attempted to tackle this question. After seven years of recruiting ~300 women, the STOP trial was stopped…
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Comparing hCG Trigger Doses in Fresh Embryo Transfer
This is the first randomized controlled multi-arm trial comparing how three hCG trigger doses impact endogenous progesterone levels in IVF- fresh embryo transfer cycles. Resources Abdalla HI, Ah-Moye M, Brinsden P, Howe DL, Okonofua F, Craft I. The effect of the dose of human chorionic…
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Caffeine, Coffee, and Pregnancy Loss
This is the first meta-analysis published in seven years to examine dose-response associations between caffeine or coffee consumption and pregnancy loss. Resources Blehar MC, Spong C, Grady C, Goldkind SF, Sahin L, Clayton JA. Enrolling pregnant women: issues in clinical research. Womens Health...
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Taking Tadalafil to Improve Embryo Implantation
This is the first study to test the use of vaginal tadalafil on endometrial thickness and pregnancies in women using IVF to conceive. Resources Balduyck J, Ameye A, Decleer W. Effect of vaginal/oral tadalafil on endometrial thickness in IVF patients: a double-blind, placebo controlled RCT: a…
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Breast Cancer & Fertility Preservation
A recent randomized controlled trial compares ovarian stimulation protocols (standard vs. tamoxifen vs. letrozole) for freezing oocytes or embryos used in women diagnosed with breast cancer.
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Liraglutide, Obesity, & PCOS
A recent well-designed American trial asked women with PCOS and obesity to take either placebo or GLP-1 agonist. 1/3 of participants were African-American and 2/3 were Caucasian. Most women had a goal of pregnancy. After 32 weeks, the women were compared for differences in weight loss, menses…
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Assisted Reproduction and Testing Positive for COVID-19
An overview of research on women who completed ICSI, IVF, and/or embryo transfer while actively or recently testing positive for SARS-CoV-2 (COVID-19).
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Stroke Risks with Infertility, Miscarriage, and Stillbirth
A large multi-national study detects higher stroke risks in women with infertility, miscarriages, and stillbirths.
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Infertility Treatment & Workplace Harassment
Resources CDC-State-Specific Assisted Reproductive Technology Surveillance. https://www.cdc.gov/art/state-specific-surveillance/index.html Accessed May 20, 2022. Herbenick D, van Anders SM, Brotto LA, Chivers ML, Jawed-Wessel S, Galarza J. Sexual Harassment in the Field of Sexuality Research.…
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New Use for Letrozole before Embryo Transfer
Letrozole with estrogen, just before progesterone: a thoughtful study on frozen embryo transfer.
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Mothers Struggle with Daughters' Infertility
This is the first study to examine the perspectives of mothers whose daughters used fertility treatments to have their first child. This study looked at how the mothers (struggled to) support their daughters.
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How Do Children from Egg Donors Feel about Their Families?
This study sought to answer how five-year-olds, born from egg donation or biological IVF, perceive their family relationships.
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Obstructive Sleep Apnea & Infertility
A large retrospective study examines how OSA relates to infertility.
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IVF Drug Waste
Disposal of Unused Medicines: What You Should Know. Food and Drug Administration Web site. https://www.fda.gov/drugs/safe-disposal-medicines/disposal-unused-medicines-what-you-should-know Accessed November 30, 2021. Drug Disposal: Drug Take Back Locations. Food and Drug Administration Web site....
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Losing Weight before IVF
Resources Anderson JW. Orlistat for the management of overweight individuals and obesity: a review of potential for the 60-mg, over-the-counter dosage. Expert Opin Pharmacother. 2007;8(11):1733-1742. doi:10.1517/14656566.8.11.1733 Best D, Avenell A, Bhattacharya S. How effective are weight-loss...
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Detecting Partner Violence in Fertility Clinics
Resources Barishansky SJ, Shapiro P, Meyman G, Pavone ME, Lawson AK. Reproductive endocrinologists' knowledge and attitudes in the identification of intimate partner violence [published online ahead of print, 2021 Sep 16]. Fertil Steril. 2021;S0015-0282(21)01934-8....
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Sexual Satisfaction, Relationship Quality, and Infertility
How relevant are a woman's feelings on getting pregnant to her sexual satisfaction? This study attempted to find out. Resources Byers ES, MacNeil S. Further validation of the interpersonal exchange model of sexual satisfaction. J Sex Marital Ther. 2006;32(1):53-69. doi:10.1080/00926230500232917...
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Crowdfunding & Fertility Treatments
A July 2021 study compared the differences in GoFundMe campaigns related to infertility based on whether or not the campaign started in a US state that requires healthcare coverage of fertility treatment.
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Semen Quality & Depression
More details can be found in the shownotes at www.yourfertilitypharmacist.com
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Fertility Treatment & Twins
More details can be found in the shownotes at www.yourfertilitypharmacist.com
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Contraceptives & AMH
For more details on the research and for other related links, please head to the shownotes at www.yourfertilitypharmacist.com
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Enbrel & Embryo Implantation
A recent study looked at the use of Enbrel (etanercept) in women with multiple failed attempts to transfer good quality IVF embryos. This is the largest study to date that has looked at using Enbrel in women with recurrent implantation failure; the results were quite promising. More details found...
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When the Doctor Says “I Don’t Know”
The first study to look at what happens when a physician talks about uncertainty with infertile couples during assisted reproductive technology (ART) consultations. More details and a link to this fertility research are available in the shownotes at www.yourfertilitypharmacist.com
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Quality of Life in Infertile Couples
This episode is about the Iranian research paper called “Resilience as the predictor of quality of life in the infertile couples as the most neglected and silent minorities.” This research was published online in November 2020 in the Journal of Reproductive and Infant Psychology. Beyond the...
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Low Dose Aspirin and the Menstrual Cycle
More details and links to the studies mentioned in this episode can be found at www.yourfertilitypharmacist.com
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Acupuncture, Mood, and PCOS
The 20th podcast episode of “Your Fertility Pharmacist” is a bit different. With guest speaker Melsa Maher, fertility acupuncturist, this episode places a special focus on traditional medicine. The audio was recorded over Zoom.
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Letrozole to Get Pregnant - Is Just One Dose Enough?
Traditionally, letrozole has been taken for five days in IUI. What happens if, instead, those five days of letrozole are taken all at once? For additional study details, please head to www.yourfertilitypharmacist.com
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BMI and Pregnancy Success in Gestational Carriers
The podcast brings up key points of the study. Scientific details and links are in the show notes at www.yourfertilitypharmacist.com
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Dietary Patterns and Ovarian Reserve
More details available at www.yourfertilitypharmacist.com
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How Do the Adult Offspring of Lesbian Parents Feel About Their Sperm Donors?
This pioneering study is the first to focus on how adults, raised by lesbian moms, feel about their sperm donors. Study originally published on July 4, 2020 in the journal Fertility and Sterility.
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Intramuscular vs. Vaginal Progesterone in Frozen Embryo Transfer
A new Harvard-affiliated study explores whether intramuscular progesterone or vaginal gel progesterone (Crinone 8%) more effectively leads to live births after single frozen embryo transfer. Will their results change IVF practices in the U.S.A.?
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Fertility Treatment and Differences in Dad IQs
A newly published study found that fathers from reproductive assistance (IVF or ICSI) had higher IQ scores than fathers who naturally conceived. This podcast discusses the flaws in the study. More at www.yourfertilitypharmacist.com
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Lower Pregnancy Rates with Prolonged Storage of Frozen Embryos
For even more details on this study, head to www.yourfertilitypharmacist.com
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Boosting Frozen Embryo Pregnancies with hCG
This podcast episode summarizes the study. For even more study details, head to www.yourfertilitypharmacist.com.
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Ectopic Pregnancy: Race, Income, Education, and Awareness
This is the first study to look at how socioeconomic factors play into women’s awareness about ectopic pregnancies. Since ectopic pregnancy is still the leading cause of maternal death in early pregnancy, ALL potentially pregnant women need to be able to recognize the seriousness of an ectopic...
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Egg Freezing at Age Seven
A 7 year old girl underwent hormone therapy and surgery to have a chance at fertility. Here were the outcomes from her two egg freezing cycles.
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Stressful Life Events and Male Factor Infertility
Some of the questions on the questionnaire included: smoking and drinking habits, self-rated physical fitness, self-rated health, socioeconomic factors (education and occupation), diseases, previous diagnosis of depression, and erectile dysfunction. To learn what differences in stress were found…
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Air Pollution and IVF Embryos
More information can be found at www.yourfertilitypharmacist.com
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ABOUT THIS SHOW
The latest fertility research presented by a board-certified clinical pharmacist. For women trying to conceive, this information can help to navigate the science behind the fertility journey.
HOSTED BY
Your Fertility Pharmacist—Infertility and Reproductive Medicine, Fertility Medications
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How many episodes does Your Fertility Pharmacist have?
Your Fertility Pharmacist currently has 58 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Your Fertility Pharmacist about?
The latest fertility research presented by a board-certified clinical pharmacist. For women trying to conceive, this information can help to navigate the science behind the fertility journey.
How often does Your Fertility Pharmacist release new episodes?
Your Fertility Pharmacist has 58 episodes. Check the episode list to see recent publication dates and frequency.
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You can listen to Your Fertility Pharmacist on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Your Fertility Pharmacist?
Your Fertility Pharmacist is created and hosted by Your Fertility Pharmacist—Infertility and Reproductive Medicine, Fertility Medications.
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