All Episodes
Authentic Biochemistry — 1203 episodes
The Immunoregulation of Cardiometabolic Diseasein Women14 Authentic Biochemistry Podcast13May26Dr. Daniel J Guerra
OxyphosphoGlycerolipid ImmunoMediated CardioMetabolic Disease. Tredecim (XIII). Authentic Biochemistry Podcast. Dr. Daniel J Guerra. 12May26
The Immunoregulation of Cardiometabolic Diseasein WomenXII Authentic Biochemistry Podcast10May26Dr. Daniel J Guerra
The Immunoregulation of Cardiometabolic Diseasein WomenXI09May26Dr. Daniel J GuerraAuthentic Biochemistry Podcast
CardioMetabolic Disease in WomenX Authentic Biochemistry Podcast Dr. Daniel J Guerra 08May26
CardioMetabolic Disease in WomenIX Authentic Biochemistry Podcast Dr. Daniel J Guerra 07May26
CardioMetabolic Disease in WomenVIII Authentic Biochemistry Podcast Dr. Daniel J Guerra 06May26
CardioMetabolic Disease in WomenVIIB Authentic Biochemistry Podcast Dr. Daniel J Guerra 05May26
CardioMetabolic Disease in WomenVII A . Authentic Biochemistry Podcast Dr. Daniel J Guerra 04May26
CardioMetabolic Disease in WomenVI Authentic Biochemistry Podcast Dr. Daniel J Guerra 03May26
CardioMetabolic Disease in WomenV Authentic Biochemistry Podcast Dr. Daniel J Guerra 02May26
CardioMetabolic Disease in WomenIV Authentic Biochemistry Podcast Dr. Daniel J Guerra 01May26
CardioMetabolic Disease in WomenIII Authentic Biochemistry Podcast Dr. Daniel J Guerra 30April26
CardioMetabolic Disease in WomenII Authentic Biochemistry Podcast Dr. Daniel J Guerra 29April26
CardioMetabolic Disease in WomenIAuthentic Biochemistry Podcast 28 April 2026. Dr Daniel Guerra
A Scientific Critique of Neuro-Correlation. Dr Daniel J Guerra Authentic Biochemistry Podcast 27April26
ImmunoEpigenetic Diaeventontological Framing CNS XX Authentic Biochemistry Podcast Dr Daniel J Guerra 26April26
Immunoepigenomic Tailoring of the CNS XIX 25April26 Dr Daniel J Guerra Authentic Biochemistry Podca
ImmunoEpigenetic Diaeventontological Framing CNS XVIII Authentic Biochemistry Podcast Dr Daniel J Guerra 24April26
ImmunoEpigenetic Diaeventontological Framing CNS XVII Authentic Biochemistry Podcast Dr Daniel J Guerra 23April26
ImmunoEpigenetic Diaeventontological Framing CNS XVI Authentic Biochemistry Podcast Dr Daniel J Guerra 22April26
ImmunoEpigenetic Diaeventontological Framing CNS XV Authentic Biochemistry Podcast Dr Daniel J Guerra 21April26
Immunoepigenetic Tailoring of the CNSXIVAuthentic Biochemistry Podcast Dr. Daniel J Guerra. 20April26
ImmunoEpigenetic as a Mechanism for Brain Development and Function A prolegomena to Ontogenic Research Event Ontology XIII. Authentic Biochemistry Podcast Dr Daniel J Guerra 19April26
Immuno Diaeventontological Framing CNS XII Authentic Biochemistry Podcast Dr Daniel J Guerra 18April26
Immuno Diaeventontological Framing CNS XI Authentic Biochemistry Podcast Dr Daniel J Guerra 17April26
ImmunoEpigenetic Diaeventontological Framing CNSXAuthentic BiochemistryPodcastDr Daniel J Guerra16April26
ImmunoEpigenetic Diaeventontological Framing CNSIXAuthentic BiochemistryPodcastDr Daniel J Guerra15April26
ImmunoEpigenetic Diaeventontological Framing CNSVIIIAuthentic BiochemistryPodcastDr Daniel J Guerra14April26
Immuno Diaeventontological Framing CNS VII Authentic Biochemistry Podcast Dr Daniel J Guerra 13April26
Immuno Diaeventontological Framing CNS VI Authentic Biochemistry Podcast Dr Daniel J Guerra 11April26
Immuno Diaeventontological Framing CNS V Authentic Biochemistry Podcast Dr Daniel J Guerra 10April26
Immuno Diaeventontological Framing CNS IV Authentic Biochemistry Podcast Dr Daniel J Guerra 09April26
Immuno Diaeventontological Framing CNS III Authentic Biochemistry Podcast Dr Daniel J Guerra 08Aprril26
The Immuno Diaeventontological Framing of the CNS II Authentic Biochemistry Podcast Dr Daniel J Guerra 07Aprril26
The Immuno Diaeventontological Framing of the CNS I Authentic Biochemistry Podcast Dr Daniel J Guerra 05Aprril26
The Natural Thermodynamics of Metabolic Regulation II Authentic Biochemistry Podcast Dr Daniel J Guerra 03APRIL26
The Natural Thermodynamics of Metabolic regulation I Authentic Biochemistry Podcast Dr Daniel J Guerra
The Statistical Thermodynamics of Metabolic Regulation,A Modest prolegomena. Dr Daniel J Guerra. Authentic Biochemistry Podcast 31 March 2026
On Metabolic Regulation Immune Network 62 Authentic Biochemistry Dr. Daniel J Guerra 30March26
Myodesopsia I
On Metabolic Regulation Immune Network 61 Authentic Biochemistry Dr. Daniel J Guerra 29March26
On Metabolic Regulation Immune Network 60 Authentic Biochemistry Dr. Daniel J Guerra 27March26
On Metabolic Regulation Immune Network 59 Authentic Biochemistry 26March26 Dr. Daniel J Guerra
Metabolic RegulationImmune Network58.Authentic Biochemistry 25March26 DR Daniel J Guerra
On Metabolic RegulationImmune Network57.Authentic Biochemistry 24March2026 DR Daniel J Guerra
On Metabolic Regulation Immune Network XXXXXVI Authentic Biochemistry Podcast Dr. Daniel J Guerra 23March26
On Metabolic Regulation Immune Network XXXXXV Authentic Biochemistry Podcast Dr. Daniel J Guerra 22March26
On metabolic regulation XXXXXIV Immune network 21March26 Dr Daniel J Guerra Authentic Biochemistry Podcast
On metabolic regulation Immune network 20March26 Dr Daniel J Guerra Authentic Biochemistry Podcast
On Metabolic Regulation XXXXXIIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 18March26
On Metabolic Regulation XXXXXIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 17March26
On Metabolic Regulation XXXXXThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 16March26
On Metabolic Regulation XXXXIXThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 15March26
Metabolic Regulation XXXXVIIIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 14March26
On Metabolic Regulation XXXXVII Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 13March26
Metabolic Regulation XXXXVIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 12March26
Metabolic Regulation XXXXVThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 11March26
Metabolic Regulation XXXXIVThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 10March26
Metabolic Regulation XXXXIIIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 09March26
Metabolic Regulation XXXXIIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 07March26
On Metabolic Regulation XXXXIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 06March.26
On Metabolic Regulation XXXXThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 05March.26
On Metabolic Regulation XXXIXThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 04March.26
On Metabolic Regulation XXXVIIIThe Immune Network Authentic Biochemistry Podcast Dr Daniel J. Guerra 03March.26
On Metabolic Regulation XXXVIIThe Immune Network Authentic Biochemistry PodcastDr Daniel J Guerra02March26
On Metabolic Regulation XXXVIThe Immune Network Authentic Biochemistry PodcastDr Daniel J Guerra01March26
On Metabolic Regulation XXXVThe Immune Network Authentic Biochemistry PodcastDr Daniel J Guerra27FEB26
On Metabolic Regulation XXXIVThe Immune Network Authentic Biochemistry PodcastDr Daniel J Guerra26FEB26
On Metabolic Regulation XXXIIIThe Immune Network Authentic Biochemistry PodcastDr Daniel J Guerra25FEB26
On Metabolic Regulation XXXIIThe Immune NetworkDr Daniel J Guerra24FEB26
On Metabolic Regulation XXXIThe Immune NetworkDr Daniel J Guerra23FEB26
Authentic Biochemistry PodcastOn Metabolic Regulation XXX Dr Daniel J. Guerra 22//2/26
Authentic Biochemistry PodcastOn Metabolic Regulation XXIX Dr Daniel J. Guerra 20//2/26
Authentic Biochemistry PodcastOn Metabolic Regulation XXVIIIDr Daniel J. Guerra 18/2/26
Authentic Biochemistry Podcast On Metabolic Regulation XXVII Dr Daniel J. Guerra 17/2/26
On Metabolic Regulation XXVI Authentic Biochemistry Podcast Dr Daniel J Guerra 16FEB26
Approaching Awareness of Biochemical Ontology 15February26Authentic Biochemistry Podcast Dr Daniel J Guerra
On Metabolic Regulation XXV Authentic Biochemistry Podcast Dr Daniel J Guerra 14FEB26
On Metabolic Regulation XXIV Authentic Biochemistry Podcast Dr Daniel J Guerra 13FEB26
On Metabolic Regulation XXIII Authentic Biochemistry Podcast Dr Daniel J Guerra 12FEB26
On Metabolic Regulation XXII Authentic Biochemistry Podcast Dr Daniel J Guerra 11FEB26
On Metabolic Regulation XXI Authentic Biochemistry Podcast Dr Daniel J Guerra 10FEB26
On Metabolic Regulation XX Authentic Biochemistry Podcast Dr Daniel J Guerra 09FEB26
On Metabolic Regulation XIX Authentic Biochemistry Podcast Dr Daniel J Guerra 08FEB26
On Metabolic Regulation XVIII Authentic Biochemistry Podcast Dr Daniel J Guerra 07FEB26
On Metabolic Regulation XVII 05FEB26 Authentic Biochemistry Podcast Dr Daniel J Guerra
On the Regulation of Metabolism XVI Authentic Biochemistry Podcast Dr. Daniel J Guerra 01FEB26
On the Regulation of Metabolism XV Authentic Biochemistry Podcast Dr. Daniel J Guerra 31January26
On the Regulation of Metabolism XIV Authentic Biochemistry Podcast Dr Daniel J Guerra 29January26
On Metabolic Regulation XIII Authentic Biochemistry Podcast 27JAN26 Dr. Daniel J Guerra
On Metabolic Regulation XII Authentic Biochemistry Podcast 26JAN26 Dr. Daniel J Guerra
On Metabolic Regulation XI Authentic Biochemistry Podcast 25JAN26 Dr. Daniel J Guerra
On Metabolic Regulation X Authentic Biochemistry Podcast 24JAN26 Dr. Daniel J Guerra
On Metabolic Regulation IX Authentic Biochemistry Podcast 22JAN26 Dr. Daniel J Guerra
On Metabolic Regulation VIII Authentic Biochemistry Podcast 21JAN26 Dr. Daniel J Guerra
On the Regulation of MetabolismVII20JAN26Authentic Biochemistry PodcastDr Daniel J Guerra
On the Regulation of MetabolismVI18JAN26Authentic Biochemistry PodcastDr Daniel J Guerra
On the Regulation of Metabolism V 17JAN26 Authentic Biochemistry Podcast Dr Daniel J Guerra
On the Regulation of Metabolism IV 16JAN26 Authentic Biochemistry Podcast Dr Daniel J Guerra
On the Regulation of Metabolism III Authentic Biochemistry Podcast Dr Daniel J Guerra. 15Jan26
On the Regulation of Metabolism 2026. II. Authentic Biochemistry Podcast. Dr Daniel J Guerra. 14Jan26
On the Regulation of Intermediary Metabolism. Prolegomena I. 13Jan2026.
PhotosynthesisVIIAuthentic Biochemistry Podcast Dr Daniel J Guerra 12JAN26
PhotosynthesisVIAuthentic Biochemistry Podcast.11January 2026.Dr Daniel J Guerra
Photosynthesis V Authentic Biochemistry Podcast Dr Daniel J Guerra 10JAN26
Photosynthesis IV Authentic Biochemistry Podcast Dr Daniel J Guerra 09JAN26
Photosynthesis IIIAuthentic Biochemistry Podcast Dr Daniel J Guerra 07Jan26
Prolegomena to PhotosynthesisAuthentic Biochemistry Podcast.06January 2026. Dr Daniel J Guerra
Photosynthesis IIAuthentic Biochemistry Podcast Dr Daniel J Guerra 05Jan26
EtOH Non Fingo XIII 31Dec25 Dr Daniel J Guerra Authentic Biochemistry Podcast
Authentic Biochemistry Podcast EtOH Non Fingo XII Dr. Daniel J. Guerra 29DEC25
Authentic Biochemistry Podcast EtOH Non Fingo XI Dr. Daniel J. Guerra 28DEC25
Authentic Biochemistry Podcast EtOH Non Fingo X Dr. Daniel J. Guerra 27DECEMBER25
Founding Reason with Modality Authentic Biochemistry Podcast Special Edition Dr Daniel J Guerra 26December 2025
Authentic Biochemistry Podcast EtOH Non Fingo IX Dr. Daniel J. Guerra 24DECEMBER25
Authentic Biochemistry Podcast EtOH Non Fingo VIII Dr. Daniel J. Guerra 23DECEMBER25
Authentic Biochemistry Podcast EtOH Non Fingo VII Dr. Daniel J. Guerra 22DECEMBER25
Authentic Biochemistry Podcast EtOH Non Fingo VI Dr. Daniel J. Guerra 21DECEMBER25
Authentic Biochemistry Podcast EtOH Non Fingo V Dr. Daniel J. Guerra 20DECEMBER25
Authentic Biochemistry Podcast. EtOH Non Fingo IV Dr. Daniel J. Guerra 19DECEMBER25
EtOH Non Fingo III Authentic Biochemistry Podcast Dr. Daniel J. Guerra 18December25
EtOH Non Fingo II Authentic Biochemistry Podcast Dr. Daniel J. Guerra 17December25
EtOH I Authentic Biochemistry Podcast Dr. Daniel J. Guerra 16 December 2025
Mitochondrial/Gut Axis NAD+ VIII Authentic Biochemistry Podcast 15DECEMBER25 Dr Daniel J Guerra.
Mitochondrial/Gut Axis NAD+ VII Authentic Biochemistry Podcast 13DECEMBER25 Dr Daniel J Guerra.
Mitochondrial/Gut Axis NAD+ VI Authentic Biochemistry Podcast 11DECEMBER25 Dr Daniel J Guerra.
NAD+/-Sirtuins in Mitochondrial Respiration and DNA Damage Repair Epigenetic Remodeling V Authentic Biochemistry Podcast 10DECEMBER25 Dr Daniel J Guerra.
NAD+/-Sirtuins in Mitochondrial Respiration and DNA Damage Repair Epigenetic Remodeling IV Authentic Biochemistry Podcast 09DECEMBER25 Dr Daniel J Guerra.
NAD+/Sirtuins in Mitochondrial Respiration and DNA Damage Repair Epigenetic Remodeling III Authentic Biochemistry Podcast 07DECEMBER25 Dr Daniel J Guerra.
NAD+/Sirtuins in Mitochondrial Respiration and DNA Damage Repair Epigenetic Remodeling II ABP 06DECEMBER25 Dr Daniel J Guerra.
NAD+/Sirtuins in Mitochondrial Respiration and DNA Damage Repair Epigenetic Remodeling I Authentic Biochemistry Podcast Dr Daniel J Guerra.5Dec25
Digestion and Absorption Insufficiencies Lipases/Proteases and the Enteroendorine/Neural Network V 03 December 25 Dr Daniel J Guerra Authentic Biochemistry Podcast
GI Digestion and Absorption Insufficiencies Lipases/Proteases and the Enteroendocrine/Neural Network IV 02 December 25 Dr Daniel J Guerra Authentic Biochemistry Podcast
GI Digestion and Absorption Insufficiencies Lipases/Proeases and the Enteroendorine/Neural Network III 30NOV25 Dr Daniel J Guerra Authentic Biochemistry Podcast
Pancreatic Exocrine Insufficiency II 29Nov25Authentic Biochemistry PodcastDr. Daniel J Guerra
On the Dialectical Order of the ArgumentPancreatic Exocrine Insufficiency I28Nov25Authentic Biochemistry PodcastDr. Daniel J Guerra
Haem-Associated protein O2 Transport and Delivery. Special lecture. Authentic Biochemistry Podcast Dr Daniel J Guerra 26 NOV25
Carbohydrate Biochemistry XXV Complex Interrogations. Authentic Biochemistry Podcast. Dr Daniel J Guerra 24Nov25
Carbohydrate Biochemistry XXIV Complex Interrogations. Authentic Biochemistry Podcast. Dr Daniel J Guerra 23Nov25
Carbohydrate Biochemistry XXIIIComplex Interrogations. Authentic Biochemistry Podcast. Dr Daniel J Guerra 22Nov25
Carbohydrate Biochemistry Complex Interrogations XXII. Authentic Biochemistry Podcast 21Nov25 Dr Daniel J Guerra
Carbohydrate Biochemistry Complex Interrogations XXI. Authentic Biochemistry Podcast 20 Nov25. Dr Daniel J Guerra
Carbohydrate Biochemistry Complex Interrogations XIX Part A Authentic Biochemistry Podcast 19NOV25 Dr Daniel J Guerra
Carbohydrate Biochemistry Complex Interrogations XIX . Part B. Authentic Biochemistry Podcast 19NOV25 Dr Daniel J Guerra
Complex Interrogations XIX Authentic Biochemistry Podcast 18NOV25 Dr Daniel J Guerra
Carbohydrate Biochemistry Complex Interrogations XVIII Authentic Biochemistry Podcast Dr Daniel J. Guerra. 17 Nov25
Authentic Biochemistry Podcast Special Edition: A biochemical knowledge event ontology. 16Nov 25 Dr Daniel J Guerra
Carbohydrate Metabolism Complex InterrogationsXVII15Nov25Authentic Biochemistry Podcast Dr. Daniel J. Guerra
Carbohydrate Metabolism Complex InterrogationsXVI14Nov25Authentic Biochemistry Podcast Dr. Daniel J. Guerra
Carbohydrate Metabolism Complex Interrogations XV Authentic Biochemistry Podcast 13 Nov25 Dr Daniel J Guerra
Carbohydrate Metabolism Complex Interrogations XIV Authentic Biochemistry Podcast 12Nov25 Dr Daniel J Guerra
Carbohydrate Metabolism Complex Interrogations XIII Authentic Biochemistry Podcast 11Nov25 Dr Daniel J Guerra
Carbohydrate Metabolism Complex Interrogations XII Authentic Biochemistry Podcast 10Nov25 Dr Daniel J Guerra
Carbohydrate Metabolism Complex Pathway Interrogations Lecture XI Authentic Biochemistry Podcast Dr Daniel J Guerra 09NOV25
Carbohydrate Metabolism Complex Pathway Interrogations Lecture X Authentic Biochemistry Podcast Dr Daniel J Guerra 08NOV25
Carbohydrate Metabolism Complex Pathway Interrogations IX Authentic Biochemistry Podcast Dr Daniel J Guerra 07NOV25
Carbohydrate Metabolism Complex Pathway Interrogations VIII Authentic Biochemistry Podcast Dr Daniel J Guerra 06NOV25
Carbohydrate Metabolism Complex Pathway Interrogations VII Authentic Biochemistry Podcast Dr Daniel J Guerra 05NOV25
Carbohydrate Metabolism Complex Pathway Interrogations VI Authentic Biochemistry Podcast Dr Daniel J Guerra 04NOV25
Carbohydrate Metabolism Complex Pathway Interrogations V Authentic Biochemistry Podcast Dr Daniel J Guerra 03NOV25
Carbohydrate Metabolism Complex Pathway Interrogations IV Authentic Biochemistry Podcast Dr Daniel J Guerra 02NOV25
Carbohydrate Metabolism Complex Pathway Interrogations III Authentic Biochemistry Podcast Dr Daniel J Guerra 01NOV25
Carbohydrate Metabolism Complex Pathway Interrogations II Authentic Biochemistry Podcast. 31 October 2025 Dr Daniel J Guerra
Carbohydrate Metabolism. Complex Pathway Interrogations I. Dr.Daniel J. Guerra, M.S. Ph.D. AUTHENTIC BIOCHEMISTRY 30OCT25.
Ischemic Stroke XX 29 October 25 Authentic Biochemistry Podcast Dr Daniel J Guerra
Tempus ad Scientia. .Authentic Biochemistry Podcast 28 October25. Dr Daniel J. Guerra
Ischemic Stroke XIX 27 October 25 Authentic Biochemistry Podcast Dr Daniel J Guerra
Ischemic Stroke XVIII 26 October 25 Authentic Biochemistry Podcast Dr Daniel J Guerra
Ischemic Stroke XVII. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra 25.10.25
Ischaemic Stroke XVI Authentic Biochemistry Podcast 24October25 Dr. Daniel J Guerra
Ischaemic Stroke XV Authentic Biochemistry Podcast 23October25 Dr Daniel J Guerra
Ischaemic Stroke XIV Authentic Biochemistry Podcast 22October25 Dr Daniel J Guerra
*Ischaemic Stroke XIII Authentic Biochemistry Podcast 21October25 Dr Daniel J Guerra
Ischaemic Stroke XII Authentic Biochemistry Podcast 20 October 25 Dr Daniel J Guerra
IS XI-B Authentic Biochemistry Podcast Dr Daniel J. Guerra 18October25
IS XI -A .Authentic Biochemistry Podcast Dr Daniel J. Guerra 18October25
Ischaemic Stroke X. 17 October 25 Authentic Biochemistry Podcast. Dr Dan Guerra
Isch-S IX 16October25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
ISCH S VIII Authentic Biochemistry Podcast 15October 2025 Dr Daniel J. Guerra
ISCHS VII Authentic Biochemistry Podcast 14October 2025 Dr Daniel J. Guerra
IS VI Authentic Biochemistry Podcast 13 October 2025 Dr. Daniel J. Guerra
IS V Authentic Biochemistry Podcast Dr Daniel J. Guerra 11October25
Ischaemic Stroke-IS IV Authentic Biochemistry Podcast Dr Daniel J. Guerra 10October25
IS III 09October25 Authentic Biochemistry Podcast Dr Daniel J Guerra
Ischaemic Stroke and Intracerebral HemorrhageII 08October25 Authentic Biochemistry Podcast Dr Daniel J GuerraI
Ischaemic Stroke and Intracerebral HemorrhageIntroduction 07October25.Authentic Biochemistry Podcast 07October25 Dr Daniel J Guerra
MS.XVII Fine. Authentic Biochemistry Podcast. Dr Daniel J Guerra 06October25
MS XVI Authentic Biochemistry Podcast Dr. Daniel J Guerra 05October25
MS XV Authentic Biochemistry Podcast Dr Daniel J Guerra 04October25
MS XIV Authentic Biochemistry Podcast Dr Daniel J Guerra 03October25
M.S. XIII Authentic Biochemistry Podcast 02September25 Dr Daniel J Guerra
MS XII Authentic Biochemistry Podcast 01Octoberr25 Dr Daniel J Guerra
M.S. XI Authentic Biochemistry Podcast 30September25 Dr Daniel J Guerra
M.S. X Authentic Biochemistry Podcast 29September25 Dr Daniel J Guerra
Multiple Sclerosis IX 28September25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra,
Multiple Sclerosis VIII 27September25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra,
Multiple Sclerosis VII 26September25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra,
Multiple Sclerosis VI 25 September25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra,
Multiple Sclerosis V 24September25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra, M.S., PhD.
Multiple Sclerosis IV 23 September25. Authentic Biochemistry Podcast Dr. Daniel J. Guerra, M.S., PhD
Multiple Sclerosis III 22 September25b Authentic Biochemistry Podcast DR Daniel J. Guerra
Multiple Sclerosis II 22 September25 Authentic Biochemistry Podcast DR Daniel J. Guerra
Disease Portrait. MULTIPLE SCLEROSIS I. Introduction. AUTHENTIC BIOCHEMISTRY PODCAST.21 Sept 25.Dr Daniel J Guerra
NeuroImmunological Tailoring in CNS Pathobiochemistry XV Authentic Biochemistry Podcast Dr. Daniel J Guerra 20 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry XIV Authentic Biochemistry Podcast Dr. Daniel J Guerra 19 September25.DSB’s as Lnkages to Neuroinflammation and Degeneration
NeuroImmunological Tailoring in CNS Pathobiochemistry XIII Authentic Biochemistry Podcast Dr. Daniel J Guerra 18 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry XII Authentic Biochemistry Podcast Dr. Daniel J Guerra 17 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry XI Authentic Biochemistry Podcast Dr. Daniel J Guerra 15 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry X Authentic Biochemistry Podcast Dr. Daniel J Guerra 14 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry IX Authentic Biochemistry Podcast Dr. Daniel J Guerra 13September25
NeuroImmunological Tailoring in CNS Pathobiochemistry VIII Authentic Biochemistry Podcast Dr Daniel J Guerra 12 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry VII Authentic Biochemistry Podcast Dr Daniel J Guerra 11 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry VI Authentic Biochemistry Podcast Dr Daniel J Guerra 10 September25
NeuroImmunological Tailoring in CNS Pathobiochemistry V Authentic Biochemistry Podcast Dr Daniel J Guerra 09 September25
Neuro Immunological Tailoring in CNS Pathobiochemistry IV Authentic Biochemistry Podcast Dr Daniel J Guerra 08 September 2025
Neuro Immunological Tailoring in CNS Pathobiochemistry III.The human neural membraneous lipidome Dr. Daniel J Guerra 07September 2025
Neuro Immunological Tailoring in CNS Pathobiochemistry II Authentic Biochemistry Dr. D.J. Guerra, PhD. 06September25
Neuro Immunological Tailoring in CNS Pathobiochemistry Authentic Biochemistry D.J. Guerra, PhD. 05September 2025
AUTHENTIC BIOCHEMISTRY PODCAST Senescence and the Immune ResponseXVII Dr. Daniel J Guerra 04September25
AUTHENTIC BIOCHEMISTRY PODCAST Senescence and the Immune ResponseXVI Dr. Daniel J Guerra 03September25
AUTHENTIC BIOCHEMISTRY PODCAST Senescence and the Immune ResponseXV Dr Daniel J Guerra
AUTHENTIC BIOCHEMISTRY PODCAST Senescence and the Immune ResponseXIV Dr Daniel J Guerra01SEPT25
Senescence and the Immune ResponseXIIIAuthentic Biochemistry Podcast Dr. Daniel J. Guerra31 August 25
Senescence and the Immune ResponseXIIAuthentic Biochemistry Podcast Dr. Daniel J. Guerra30 August 25
Senescence and the Immune ResponseXIAuthentic Biochemistry Podcast Dr. Daniel J. Guerra29August 25
Senescence and the Immune ResponseXAuthentic Biochemistry PodcastDR Daniel J. Guerra28 August 25
Senescence and the Immune Response IXAUTHENTIC BIOCHEMISTRY PODCASTDr Daniel J Guerra27Aug25
Significance and Necessity of Cholesterol and All Prenyl Lipids in Human Biology. The Competitive Inhibitory Longanimity of HMG CoA Reductase . Dr. Daniel J Guerra 25AUG25 Authentic Biochemistry
Senescence and the Immune Response VIIIAUTHENTIC BIOCHEMISTRY PODCASTDr Daniel J Guerra24Aug25
Metabolic Zonation and the Anabolic/Catabolic DEOSenescence and the Immune Response VIIAUTHENTIC BIOCHEMISTRY PODCASTDr Daniel J Guerra22Aug25
Senescence and the Immune Response. The CNS Architectonic.VI.AUTHENTIC BIOCHEMISTRY PODCAST.Dr Daniel J Guerra.21Aug25
Senescence and the Immune Response V AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J Guerra 20Aug25
Senescence and the Immune Response IV AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J Guerra 19Aug25
Senescence and the Immune Response III AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J Guerra 18Aug25
Senescence and the Immune Response II AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J Guerra 17Aug25
Senescence and the immune Response I AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J Guerra 15Aug25
Immunological Pathobiochemistry Obesity in Pregnancy and Lactation 4 XVII Authentic Biochemistry Podcast Dr. Daniel J Guerra 14AUG25
Immunological Pathobiochemistry. Obesity in Pregnancy and Lactation 3 XVI Authentic Biochemistry Podcast Dr, Daniel J Guerra 13AUG25
Immunological Pathobiochemistry Obesity in Pregnancy and Lactation 2 XV Authentic Biochemistry Podcast Dr, Daniel J Guerra 12AUG25
Immunological Pathobiochemistry : Obesity in Pregnancy and Lactation XIV Authentic Biochemistry Podcast Dr, Daniel J Guerra 11AUG25
Immunological Pathobiochemistry XIII Authentic Biochemistry Podcast Dr, Daniel J Guerra 09AUG25
Immunological Pathobiochemistry XII Authentic Biochemistry Podcast Dr, Daniel J Guerra. 08AUG25
Immunological Pathobiochemistry XI 06August 25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra
Immunological Pathobiochemistry X 05 August 25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra
Immunological Pathobiochemistry IX 04 August 25 Authentic Biochemistry Podcast Dr. Daniel J. Guerra
Immunological Pathobiochemisty VIII Dedicated to Maggie Authentic Biochemistry Podcast 03AUG25 Dr Daniel J. Guerra
The Immunology of Obesity Linked PathoBiochemistry VII AUTHENTIC BIOCHEMISTRY PODCAST 01August25 Dr Daniel J Guerra
The Immunology of Obesity Linked PathoBiochemistry VI AUTHENTIC BIOCHEMISTRY PODCAST 30July25 Dr Daniel J Guerra
The Immunology of Obesity Linked PathoBiochemistry V AUTHENTIC BIOCHEMISTRY PODCAST 29July25 Dr Daniel J Guerra
The Immunology of Obesity Linked PathoBiochemistry IV AUTHENTIC BIOCHEMISTRY PODCAST 28July25. Dr. Daniel J Guerra
The Immunology of Obesity linked PathoBiochemistry III. 26July25.Authentic Biochemistry Podcast Dr. Daniel J Guerra
The Immunology of Obesity linked PathoBiochemistry II. Dr Daniel J Guerra Authentic Biochemistry Podcast Video. 25July25
The Immunology of Obesity linked PathoBiochemistry I. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.24July25
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of DiseaseXV Authentic Biochemistry Podcast Dr Daniel J Guerra 23JUly 25
Special Summer Sunday Evening Lecture: Quantum Metaphysics & CytoEpigenetics. Dr. Daniel J. Guerra Authentic Biochemistry Podcast.
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease. XIII. Authentic Biochemistry Podcast Dr Daniel J Guerra 18July25
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease XII Authentic Biochemistry Podcast Dr Daniel J Guerra 18July25
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease XI Authentic Biochemistry Podcast Dr Daniel J Guerra 17July25
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease X Authentic Biochemistry Podcast Dr Daniel J Guerra 14July25
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease IX Authentic Biochemistry Podcast Dr Daniel J Guerra 13July25
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease Revisitation to AD. VIII. Authentic Biochemistry Podcast 12July25 Dr. Daniel Guerra
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease VII.Authentic Biochemistry Podcast 11July25 Dr. Daniel Guerra
Lipid Mediated Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease VI CVD and Infection Authentic Biochemistry Podcast Dr Daniel J Guerra 10July25
Subcellular Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease V IEM, Cancer, and Neurodegeneration Authentic Biochemistry Podcast Dr Daniel J Guerra 08July25
Lipid Subcellular Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease IV IEM, Cancer, and Neurodegeneration Authentic Biochemistry Podcast Dr Daniel J Guerra 07July25
Lipid Mediated Subcellular Cytoepigenetic Events Promote Immune Responses in Potential Mitigation of Disease III IEM, Cancer, and Neurodegeneration Authentic Biochemistry Podcast Dr Daniel J Guerra
Revisiting the Immune and Neuropathology of CYTOEPIGENETICS II.Dr. Daniel J. Guerra 04JULY25
Revisiting the Immune and Neuropathology of CYTOEPIGENETICS Dr. Daniel J. Guerra 03JULY25
Biochemistry of Thermodynamic Accomodations XIV. Authentic Biochemistry Podcast. Dr. Daniel J Guerra. 01JULY25
Authentic Biochemistry Podcast Membrane Thermodynamics XIII 26June25 Dr Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. XII 25June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. XI 23June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. X 22June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. IX. 21June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. VIII 20June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. VII. 18June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Membrane Biochemistry Interlude Thermodynamics VI. 17 June 25 AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. V 16June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. IV 14June25 Authentic Biochemistry Podcast Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations. III. 13une25. Authentic Biochemistry Podcast. Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations II. 11June25.Authentic Biochemistry Podcast .Dr. Daniel J Guerra
Biochemistry of Thermodynamic Accommodations I .The convention of The Eventic a Priori Authentic Biochemistry Podcast Dr Daniel J Guerra 09June 25
Brevis dialectica purae Scientiae. Authentic Biochemistry Podcast Dr Daniel J Guerra 07June25
FAS/PHARM. Session XXIII. Authentic Biochemistry Podcast Dr. Daniel J Guerra06June25
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets XXII Authentic Biochemistry Podcast Dr Daniel J Guerra 5June25
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets XXI. Dr Daniel J Guerra 04June25
Fatty Acid Metabolism: Apprehending Pharmacotherapeutic Targets. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 02June25.
A Metaphysical Moment: The Either/Or of Never Giving an Inch. Authentic Biochemistry Podcast. Dr Daniel J Guerra. 01June25
Fatty Acid Metabolism. Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast Dr. Daniel J. Guerra 31MAY25
Fatty Acid Metabolism/PHARMA XVIII.30May 25. Authentic Biochemistry Podcast. Dr. Daniel J Guerra
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets. 28May25. Authentic Biochemistry Podcast. Dr. Daniel J Guerra.
Fatty Acid Metabolism Apprehending Pharmaceutical Targets XVI. Authentic Biochemistry Podcast 26MAy 25 Dr Daniel J Guerra
Fatty Acid Metabolism: Apprehending Pharmacotherapeutic Targets XV AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J. Guerra 25May 25
Fatty Acid Metabolism: Apprehending Pharmacotherapeutic Targets XIV. AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J. Guerra 24 May 25
Fatty Acid Metabolism: Apprehending Pharmacotherapeutic Targets XIII AUTHENTIC BIOCHEMISTRY PODCAST Dr Daniel J. Guerra 22May 25
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets XII. Dr Daniel J. Guerra 21 May 25
Fatty Acid Biochemistry Apprehending Pharmacotherapeutic Targets XI. Authentic Biochemistry Podcast. Dr Daniel J Guerra 20May25
Fatty Acid Biochemistry Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast Dr Daniel J Guerra X 18May25
Fatty Acid Biochemistry Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast Dr Daniel J Guerra IX 16May25
Fatty Acid Biochemistry Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast. Dr Daniel J Guerra VIII. 14May25
Fatty Acid Biochemistry Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast Dr Daniel J Guerra VII. 13May25
Fatty Acid Biochemistry Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast Dr Daniel J Guerra VI 12May25
Fatty acid metabolism V Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast Dr Daniel J Guerra 11May25
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets IV Authentic Biochemistry Podcast 09MAY25 Dr Daniel J Guerra
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets III Dr Daniel J Guerra 08May25
Fatty Acid Metabolism Apprehending Pharmacotherapeutic Targets II Authentic Biochemistry Podcast 06MAY25 Dr Daniel J Guerra
Fatty Acid Metabolism. Apprehending Pharmacotherapeutic Targets Authentic Biochemistry Podcast In Memorium to John B Ohlrogge. PhD 05MAY25 Dr Daniel J. Guerra
Epigenetic Intrusion Manifesting Florid Glioblastoma V. Authentic Biochemistry Podcast. Dr Daniel J Guerra 03 May 25
Epigenetic Intrusion Manifesting Florid Glioblastoma IV. Authentic Biochemistry Podcast Dr Daniel J Guerra 02 May 25
Epigenetic Intrusion Manifesting Florid Glioblastoma. III .Authentic Biochemistry Podcast Dr Daniel J Guerra 29April25
Epigenetic Intrusion Manifesting Florid Glioblastoma II. Authentic Biochemistry Podcast Dr Daniel J Guerra 28April25
Epigenetic Intrusion Manifesting Florid Glioblastoma. Authentic Biochemistry Podcast Dr Daniel J Guerra 27April25
CAR-T Lymphocytes VII. FINE. Authentic Biochemistry Podcast Dr. Daniel J. Guerra. 24April25
CAR-T Cells VI. Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 23April25
CAR-T Cells V. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 21April25
A Metaphysical Offering in Chemical Thermodynamics for Easter
CAR T Lymphocytes IV Authentic Biochemistry Podcast Dr Daniel J. Guerra 17April25
CAR-T Lymphocytes III. Authentic Biochemistry Podcast. Dr Daniel J Guerra 16 APRIL 25
Chimeric Antigen Receptor T Lymphocytes .II Authentic Biochemistry Podcast. Dr Daniel J Guerra. 14April25
Chimeric Antigen Receptor T Lymphocytes. I. Authentic Biochemistry Podcast..13APRIL25
An Immunological Framing of Neurotransmission. XXI CODA. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 11April25
An Immunological Framing of Neurotransmission XX Authentic Biochemistry Podcast Dr Daniel J Guerra 10April25
An Immunological Framing of NeurotransmissionXIX Authentic Biochemistry Podcast Dr Daniel J Guerra 08April25
An Immunological Framing of Neurotransmission XVIII Authentic Biochemistry Podcast Dr Daniel J Guerra 06April25
An Immunological Framing of Neurotransmission. XVII. Authentic Biochemistry Podcast . Dr Daniel J Guerra .03APRIL25
An Immunological Framing of Neurotransmission XVI. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 01April25.
An Immunological Framing of Neurotransmission XV. Authentic Biochemistry Podcast. Dr Daniel J Guerra. 31 March 2025.“How Terribly Strange…”.
An Immunological Framing of Neurotransmission Vignette Lecture Reactive Oxygen MetabolismXIV 27March25 Authentic Biochemistry Podcast Dr Daniel J Guerra
An Immunological Framing of Neurotransmission XIII. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 22March25
An Immunological Framing of Neurotransmission XII Authentic Biochemistry Podcast.Dr. Daniel J Guerra 21 March 25
An Immunological Framing of Neurotransmission XI Authentic Biochemistry Podcast Dr. Daniel J. Guerra 18 March25
An Immunological Framing of Neurotransmission X Authentic Biochemistry Podcast Dr. Daniel J. Guerra 17MARCH25
An immunological Framing of Neurotransmission IX. Authentic Biochemistry Podcast Dr Daniel J. Guerra 15March25
Immunological Framing of Neurotransmission. Primer Interlude A. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 14March25
An Immunological Framing of Neurotransmission VII Authentic Biochemistry Podcast Dr. Daniel J Guerra 12March25
An Immunological Framing of Neurotransmission VI. Authentic Biochemistry Podcast 11March25 Dr. Daniel J. Guerra
An Immunological Framing of Neurotransmission V Authentic Biochemistry Podcast 10March25 Dr. Daniel J. Guerra
An Immunological Framing of Neurotransmission. IV. Authentic Biochemistry Podcast IV. Dr Daniel J. Guerra. 06MARCH25.
An Immunological Framing of Neurotransmission III Authentic Biochemistry Podcast Dr Daniel J Guerra 05March2025
An immunological Framing of Neurotransmission II Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 03MARCH2025
An immunological Framing of Neurotransmission. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 02MaRCH2025
A prior Metabolic Architectonics XXV.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.25FEB25
A priori Metabolic Architectonics XXIV. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra 23FEB25
A priori Metabolic Architectonics XXIII. Authentic Biochemistry Podcast. Dr Daniel J. Guerra.21FEB25
Authentic Biochemistry Podcast A priori Metabolic Architectonics XXII Dr Daniel J. Guerra 19FEB25
A priori Metabolic Architectonics XXI. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.16FEB25.
A priori Metabolic Architectonics XX. Authentic Biochemistry Podcast. Dr Daniel J. Guerra.14FEB25
A priori Metabolic Architectonics XIX.Authentic Biochemistry Podcast Dr Daniel J Guerra 12FEB25.
A priori Metabolic Architectonics. XVIII. 10FEB25 Authentic Biochemistry Podcast. Dr Daniel J. Guerra.
A priori Metabolic Architectonics XVII. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.07FEB25.
A priori Metabolic Architectonics. XVI. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra 05FEB25
A priori Metabolic Architectonics XV. Authentic Biochemistry Podcast. Dr.Daniel J. Guerra. 02FEB25
A priori Metabolic Architectonics. XIV. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra 01FEB25.
A priori Metabolic Architectonics XIII. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.30JAN25
A priori Metabolic Architectonics XII. Authentic Biochemistry Podcast. Dr. daniel J. Guerra 28Jan25
A priori Metabolic Architectonics XI. Dr Daniel J. Guerra. Authentic Biochemistry Podcast 25JAN25.
A Priori Metabolic Architectonics X. Authentic biochemistry Podcast. Dr. Daniel J. Guerra. 23Jan25
A priori Metabolic Architectonics IX. Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 19Jan25
A priori Metabolic Architectonics VIII. AUthentic Biochemistry Podcast . Dr. Daniel J. Guerra. 18January25
A priori Metabolic Architectonics VII. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra 16January25
A priori Metabolic Architectonics VI. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.13January25
A priori Metabolic Architectonics V. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 10January25
A priori Metabolic Architectonics IV. Dr. Daniel J. Guerra Authentic Biochemistry Podcast .09January 25
A priori Metabolic Architectonics III. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 7Jan25
A priori Metabolic Architectonics in Obesity and Hepatic Disease II. Authentic Biochemistry Podcast . Dr Daniel J. Guerra 06JAN25
A priori Metabolic Architectonics I. Dr. Daniel J. Guerra 04January 2025. Authentic Biochemistry Podcast.
EtOH IV. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 01January25
EtOH III. authentic Biochemistry Podcast. Dr. Daniel J. Guerra.31December24.
Authentic Biochemistry Podcast . EtOH II. Dr. Daniel J. Guerra.29December24
EtOH I. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra. 28December24.
Cell Surfaces Alter Cellular Biochemical Events Beyond the Level of Molecular Genetics and Instantiating Epigenetic Chromatin Alterations XVII Authentic Biochemistry Podcast.DJGPhD..26.12.24.Sequalae
Cell Surface Mediated Bioenergetics linked to enzymatic regulation of cytosolic and mitochondrial networking events requires gate-keeping allostericism of contrarian metabolic flux. DJGPhD.26.12.24
Cell Surface Ontology in Physiology and Metabolism Lecture in series XV Lipogenesis and the PEPCK association .Dr. Daniel J Guerra 21December24.
Authentic Biochemistry Podcast Cell Surface Biochemistry XIV. Adipogenesis.Dr Daniel J. Guerra 19December24
Authentic Biochemistry Podcast . Cell-Surface Biochemical Interactions XIII Immune Cell Adaptation and Adhesion Protein –Mediated Chronic Inflammation Dr Daniel J. Guerra 17December24.
Authentic Biochemistry Podcast .Cell-Surface Mediated Protein Kinetics. & Dynamics XII Dr Daniel J. Guerra .14December24.
Cell Surface Mediated ER-Stress Modulated Cytoskeletal Protein Interactions Rescue Fatty Acid Uptake for Ovarian Cancer Infiltrating CD8+T 's. Authentic Biochemistry Dr. Daniel J Guerra 09December24
Authentic Biochemistry Podcast Membrane Gycolipid and Glycoprotein interlocution drives GPI-anchoring. X. Dr. Daniel J. Guerra 06December24
Authentic Biochemistry Podcast. Cell Surface Mediated Enzyme Regulation IX. CD8+TCell Immunosuppression. Dr Daniel J. Guerra. 03Dec24
Authentic Biochemistry Podcast Cell Surface Enzymology VIII Dr Daniel J. Guerra 29November24
Authentic Biochemistry Podcast Cell Surface Enzymology VII. Fret Matrix Metalloprotease Interrogations I. 26Nov24 Dr Daniel J. Guerra.
Authentic Biochemistry Podcast. Cell Surface Enzyme Kinetics VI. Dr Daniel J Guerra 21Nov.24.
Authentic Biochemistry Podcast. Eventuating Nature of Intrinsic Cell Surface Complexity.V. Dr. Daniel J. Guerra.18NOV24
Authentic Biochemistry Podcast Cell Surface mediated Enzyme Modulation: IV. Anionic Phosphoglycerolipids & GPCR’s Dr Daniel J. Guerra 15November24
Authentic Biochemistry Podcast. Cell-Surface Enzymology: Blood Clotting and GPCR's Dr Daniel J. Guerra. 12Nov24
Cell surface Mediated Enzyme Event Ontology. II Quantitative Enzymology Primer Dr Daniel J. Guerra Authentic Biochemistry 10November24
Cell-Surface Mediated Regulation of Enzyme Kinetics/Dynamics. Authentic Biochemistry .DJGPhD. 8nov24
Authentic Biochemistry Podcast. PTM's VII. The Integration of metabolism is engraved posttranslationally on proteins organized to conduct cellular reorganization and fate. DJGPhD. 05 November24
AUTHENTIC BIOCHEMISTRY PTM VI. DJGPhD 31.10.24
Authentic Biochemistry Podcast. PTM's V. Unique Autocatalytic Cholesterylation of a HedgeHog Signaling GPCR. Dr Daniel J. Guerra 29OCTOBER24
Protein Post Translational Modifications IV. Authentic Biochemistry Podcast Dr. Daniel J. Guerra 26October24
Dolichol-PP Driven ER Glycosyl PTM’s Authentic Biochemistry Podcast Dr. Daniel J. Guerra 21October24
Protein PTM Diseases Associated with Epigenetic Phenomena II Type I Diabetes and lncRNA’s. AUTHENTIC BIOCHEMISTRY PODCAST.DR DANIEL J. GUERRA.18 OCTOBER 2024
Protein PTM Diseases Associated with Epigenetic Phenomena I. AUTHENTIC BIOCHEMISTRY PODCAST.DR DANIEL J. GUERRA. 15 OCTOBER 2024.
Sarcopenia XVII Fine. Authentic Biochemistry Podcast. 12October 24 Dr Daniel J. Guerra.
Authentic Biochemistry Podcast. Sarcopenia XVI. Phosphatidic Acid and the mTORC axis of Muscle Protein Translation.DJGPhD10 October 24
Authentic Biochemistry Podcast Sarcopenia XV Dr. Daniel J. Guerra 09OCTOBER24
Authentic Biochemistry. Sarcopenia XIV. Dr Daniel J. Guerra 08October24.
Authentic Biochemistry Podcast. Sarcopenia XIII Lipid Utilization via Perilipin/CD36 and Spatiotemporal Framing. Dr Daniel J Guerra 07OCTOBER24
Authentic biochemistry Sarcopenic Lipid and Oxidative Metabolism XII Dr Daniel J Guerra 04OCTOBER24
Sarcopenia XI The Membrane Lipid Domains Dr Daniel J. Guerra.03October24
Authentic Biochemistry Podcast Sarcopenia X Senescence Dr Daniel J. Guerra 30September24
Sarcopenia IX. The Interplay of quinone reductase and PGC1-alpha in mitochondrial event dynamics. Dr. Daniel J. Guerra. 28.9.24
Sarcopenia VIII. Parkin expression in adipose linked to bioenergetics and mitochondrial fate associated muscle metabolism. DJGPhD.25.9.24
Sarcopenia VII Authentic Biochemistry Podcast. Dr Daniel J. Guerra 23.9.24
A Dialectical Eventual Disclosure of Metabolic Temporality. Dr Daniel J. Guerra. 21Sept24. Authentic Biochemistry Podcast
Authentic Biochemistry Podcast. Sarcopenia VI. Dr Daniel J. Guerra 19. 9.24
Authentic Biochemistry Podcast Sarcopenia V. Dr. Daniel J. Guerra 16.9.24
Sarcopenia IV. The CH20 Signaling Metabolome Circuit Involving the CNS, Liver, Adipose and Skeletal Muscle. Authentic Biochemistry Podcast Dr. Daniel J. Guerra 14.9.24
Authentic Biochemistry Podcast Sarcopenia.C.3 AMPK Control over Pyrimidine and Purine biosynthesis via mTORC. Dr. Daniel J. Guerra. 11Sept24
Sarcopenia C.2 Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 10Sept24
Sarcopenia Molecular Pathology. Dr. Daniel J. Guerra. 09Sept24. Authentic Biochemistry Podcast
Concerning Technical Difficulties on the Recent Video Lectures.DJGPhD.08Sept24.
Authentic Biochemistry Podcast. Alzheimer’s Disease coda. Dr Daniel J Guerra.04sept24
Authentic Biochemistry Podcast Moment. Dr Daniel J Guerra. 03Sept24
Authentic Biochemistry Podcast. Pharmacotherapeutic drug mechanisms and their molecular targets in AD. DJGPhD.02September24.
Authentic Biochemistry Podcast. The Insulin Involvement in Kinase Cascade Expansion of Tau and A- β Pathology 01September 2024 Dr. Daniel J. Guerra
Authentic Biochemistry Podcast Sphingolipids and Kinase Modulatory Influences on AD Proteinopathies 30 August 2024 Dr. Daniel J. Guerra
Authentic Biochemistry Podcast Alzheimer's Disease Pathobiochemical Inception Involves Mitochondrial Dysfunction. Dr. Daniel J. Guerra.27.8.24.
Authentic Biochemistry Podcast. Primer; Nucleotide Biochemistry I DJGPhD.25.8.24
Authentic Biochemistry PodcastIntermediary metabolism, epigenetics, and the endomembranous network surveil, ascertain, and deliver upon cellular event ontology Including AD pathology.DJGPhD.24.8.24
Sphingolipids in AD: The Fragmentation of Mitochondrial DNA and Innate-Immune activation of inflammasomal CNS pathologies Dr Daniel J. Guerra 23.8.24 Authentic Biochemistry Podcast
AD is a Neurodegenerative Disease associated with Cytoepigenetic Interactions between the Nuclear and Mitochondrial Genomes. Authentic Biochemistry Podcast.c.8.Dr. Daniel J. Guerra.19.8.24
Immune and neuropathophysiology of CYTOEPIGENETICS Dr. Daniel J. Guerra 18AUGUST 202
Authentic Biochemistry Podcast Sphingolipid, ROS Mitochondrial Involvement associated with Nuclear Histone Acetylation in Alzheimer’s Disease 14.8.24 Daniel J. Guerra, PhD
Inter Alia, The PDH/LDH/PDHK Axis for T Lymphocyte Activation intersection with AD pathobiochemistry. DJGPhD. 12AUG24
AD and Sphingolipids c.5 Sphingomyelinase and Ceramide molecular heterogeneity in AD is associated with bioenergetics and Ketone availability. Authentic Biochemistry. 11Aug24 Dr. Daniel J. Guerra
Authentic Biochemistry Podcast. Sphingolipids and Alzheimer’s Disease c.4 [09AUGUST24] Dr Daniel J. Guerra
Sphingolipids and AD. c.3. 07Sept 24.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra
Authentic Biochemistry Podcast . Alzheimer's Disease involves intercellular trafficking of A-beta to the microglia via ceramide stereoisomer specified exosomal transport. c.2. DJGPhD.05Sept24
Authentic Biochemistry Podcast. “Scientism non fengo” Dr Daniel J. Guerra 02August24
Authentic BiochemistryPodcast. Sphingolipid Involvement in AD. c.1. 01August 2024. Dr Daniel J. Guerra
Photosynthesis. IV. Authentic Biochemistry Podcast. Dr Daniel J. Guerra.31.7.24
Photosynthesis III. Midsummer. Authentic Biochemistry Podcast.DJGPhD.29.7.24
Authentic Biochemistry Midsummer Lecture Series. Plant Biochemistry Interlude II. Chloroplast Lipids and Photosynthesis. 27.7.24.
Authentic Biochemistry Midsummer Lecture Series. Plant Biochemistry Interlude. Photochemistry I. Dr Daniel J. Guerra 26.7.24
Immune Cell Biochemistry. B cells C.23 Postscript Authentic Biochemistry Podcast. Dr Daniel J. Guerra 23.7.24
Saturday evening biochemical metaphysics. Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 20.7.24
Immune Cell Biochemistry II. B lymphocytes. c.22. Final Synthesis Authentic Biochemistry Podcast Dr. Daniel J. Guerra 18.7.24
Immune Cell Biochemistry II. B lymphocytes. c.21. CD38 NAD+ hydrolase mediates the Inflammatory Response Authentic Biochemistry Podcast Dr. Daniel J. Guerra 16.7.24
The Prevailing Gignesthai of Biological Systems: “In inceptum finis est”.Dr. Daniel J. Guerra. Authentic Biochemistry Podcast. Lectures on Biochemical Epistemology.14.7.24
Immune Cell Biochemistry II. B lymphocytes. c.20. The gignesthaic a priori events controlling pro and anti-oxidative metabolism are linked to the core circadian oscillator complex via multiple events.
Immune Cell Biochemistry II, c.19. Fine e. CNS and Immune B cell Sirtuin and melatonin regulation of inflammation and gene expression in senescence and disease. DJGPhD.11.July.24.
Immune Cell Biochemistry.Authentic Biochemistry Podcast Glucosyl Ceramide and NAD+. B cells lecture c.18 Fine d July 9, 2024 Dr Daniel J. Guerra
Immune Cell Biochemistry. Authentic Biochemistry Podcast Multiple Myeloma Sphingosine 1-P Associations. B cells lecture c.17 Fine (c) July7, 2024 Dr Daniel J. Guerra
Dialectical Synthesis IV. The GABA/Glutamate axis and the complexity of symmetry composed a priori. DJGPhD.03July24. Authentic Biochemistry Podcast
Immune Cell BiochemistryAuthentic Biochemistry Podcast Multiple Myeloma Dyslipidaemia B cells lecture c.16 FineB July2, 2024 Dr Daniel J. Guerra
Immune Cell Biochemistry.Authentic Biochemistry Podcast Multiple Myeloma Dyslipidaemia. B cells lecture c.15 Fine(a) 30.6.24 Dr Daniel J. Guerra. Authentic Biochemistry.
Dialectical Synthesis Lecture III. The Necroptotic event in cell fate through the lens of categorical synthesis of the a priori. Dr Daniel J. Guerra. authentic Biochemistry Podcast 28.6.24
Immune Cell Biochemistry. B cells. The XIST-RNP complex with histone epigenetic alteration of Xi -linked genomic loci mediates SLE and RA in women. DJGPhD. 25.6.24. Authentic Biochemistry Podcast
Dialectical Synthesis Lecture II. 23.6.24 The Apothecary of the Alternative a priori: of Programmed cell death ontology. Dr Daniel J. Guerra Authentic Biochemistry Podcast
Authentic Biochemistry: Dialectical Syntheses Toward an Improved Evaluation of Biochemical Research. Dr Daniel J. Guerra.20.6.24.
Immune Cell Biochemistry II. B-lymphocyte partially silenced X-chromosome -specific amplification of idiotypic (nc) L-RNA translation products and autoimmunity in women. DJGPhD.19.6.24
Immune Cell Biochemistry. B cells C.12. Epigenetic Regulation. Dr Daniel. J. Guerra.17.6.24.Authentic Biochemistry Podcast
Immune Cell Biochemistry. Bcell Electron transport control via calcium mobilization after BCR activation. DJGPhD. 14.6.24. Authentic biochemistry Podcast
Immune Cell Biochemistry.c.10 Primer on Mitochondrial Bioenergetics I. DJGPhD.13.6.24
Immune Cell biochemistry. BCR activation results in mitochondrial alteration in ETC and OXPHOS. DJGPhD. 12June24 Authentic Biochemistry.
Immune Cell Biochemistry II. B cells. Two-component B cell activation requires Tfh and/or TLR9 signaling to mediate glucose metabolism for bioenergetic demands. DJGPhD. 10June24
Immune Cell Biochemistry B lymphocyte c.7
Immune Cell Biochemistry II.B lymphocyte VDJ recombination is controlled by multiple methyltransferase mechanisms. Dr Daniel J. Guerra. 01June2024.Authentic Biochemistry.
Immune Cell Biochemistry II. B cells The Methyltransferase regulation of RAG 2. Dr Daniel J. Guerra. 29May24. Authentic Biochemistry Podcast
Immune Cell Biochemistry II. B Cell Event Ontology. 28May24. Authentic Biochemistry Podcast. Dr Daniel J. Guerra
Immune Cell Biochemistry II. Authentic Biochemistry Podcast. B cell Biochemistry c4. Dr Daniel J. Guerra 27.5.24.
Authentic Biochemistry Podcast. B-Cell Membrane Biochemistry.c.3. Dr. Daniel J. Guerra. 26.5.24
Authentic Biochemistry Podcast. B Cell Membrane Biochemistry.c.2.Dr. Daniel J. Guerra. 25.5.24
Immune Cell Biochemistry II. B Cell Membranes. Introductory Lecture. Dr Daniel J. Guerra. 22May24 Authentic Biochemistry.
Authentic Biochemistry Podcast Philosophical Interlude. The Epistemological concurrence of biochemical research with dialectical event ontology. Dr Dan Guerra 20.5.24.
T cell Membrane Biochemistry. FINE c.25. 18 May 2024.Authentic Biochemistry Podcast.Dr Daniel J. Guerra
T Cell Membrane Biochemistry Fine C24. Endometrial Cancer NK cells:a biochemical pseudoparadox revealing event ontology dialectics. Dr Daniel J. Guerra. 17.5.24
Authentic Biochemistry Podcast. T cell Membrane Lipid Biochemistry c.23 Fine I. 15.5.24. Dr. Daniel J. Guerra
Immune Cell Biochemistry. T cell Membranes Coda VII. C.22 Dr Daniel J. Guerra. Authentic Biochemistry 13.5.24
Immune Cell Biochemistry. T cell Membranes. Coda VI. c.21 Methylation Specific Treg differentiation I. 11May24. DJGPhD Authentic Biochemistry Podcast
Immune Cell Biochemistry.Tcell Membranes. Coda V. C.20
Immune Cell Biochemistry I. T cell Membrane Biochemistry. CODA-IV. C.19. Authentic Biochemistry Podcast. Dr. Daniel J. Guerra . 07May24
Immune Cell Biochemistry I. T Cell Membranes CoDA3/C.18 Authentic Biochemistry Dr. Daniel J. Guerra 06MAY24
Immune Cell Biochemistry I. T Cell Membranes c.17 Authentic Biochemistry Dr. Daniel J. Guerra 05MAY24
Immune Cell Biochemistry I. T cell Membrane Biochemistry.CODA 1.Authentic biochemistry Podcast.Dr. Daniel J. Guerra
Immune Cell Biochemistry I. T Lymphocyte Membrane.C.15. Authentic Biochemistry Podcast.Dr Daniel J. Guerra.01May2024.
Immune Cell Biochemistry I. T Lymphocyte Membrane.C.14 Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 30.4.24 .
Immune Cell Biochemistry I. T Lymphocyte Membrane c.13. Authentic Biochemistry Podcast. Dr .Daniel J. Guerra.28.4.24 .
Immune Cell Biochemistry I. T Lymphocyte Membrane Biochemistry c.12. Omega -3 fatty acids and mdiminished macrophage inflammatory gene expression. Dr. Daniel J. Guerra Authentic Biochemistry 26..4.24
A brief introduction to an epistemological dialectic directed toward research science. Dr. Daniel J. Guerra. 25.4.2924. Authentic Biochemistry Podcast
Immune Cell Biochemistry I. T Lymphocyte Membrane Biochemistry c.11. Dr. Daniel J. Guerra. Authentic Biochemistry. 24.4.24
Immune Cell Biochemistry I. T Lymphocyte Membrane Biochemistry c.10. Immune cell membrane glycosphingolipids. Dr. Daniel J. Guerra Authentic Biochemistry 23.4.24.
Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry. c.9. The involved CH2O sequence event ontology. DJGPhD.22.4.24
Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.8. 20April 2024.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra.
Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry. c.7. .18April 2024.Authentic Biochemistry Podcast. Dr. Daniel J. Guerra
Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.6. 17April 2024.Authentic Biochemistry Podcast.Dr. Daniel J. Guerra.
T lymphocyte Membrane Biochemistry I. Immune Cell Biochemistry I c.5 Authentic Biochemistry 16April2024 Dr Daniel J. Guerra
Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.4. 15April 2024. Chemokine gradients and the membrane lipid raft. Authentic Biochemistry Podcast Dr. Daniel J. Guerra
Immune Cell Biochemistry I. T lymphocyte Membrane Biochemistry c.3. 14 April 2024 .Authentic Biochemistry Podcast.Dr. Daniel J. Guerra
Immune Cell Biochemistry I.T lymphocyte Membrane Biochemistry c.2 Lipid mespmorph and radius assymetry direct Tcell membrane sterol and protein interdigitation that is altered by pressure via PV=nRT.
Immune Cell Biochemistry I.T lymphocyte Membrane Biochemistry c.1. DJGPhD.11April24.Authentic Biochemistry Podcast
Biochemical Mosaic III. Coda. DJGPhD .09April24.Authentic Biochemistry Podcast
Biochemical Mosaic III. c.14. From physical chemistry to the mechanisms of sphingomyelinase mediated inflammation: abrief dialectical accounting of research involving abiotic vs biological phenomena.
Biochemical Mosaic III.c.13. A priori intralocution of inflammasome genomic loci with stress phenomena immunoepigenetically resolves defensive inflammation. DJGPhD.6April24. Authentic Biochemistry.
Biochemical Mosaic III. c12. A prolegomena to any future biochemical Instanence. Dr Daniel J. Guerra. 4April2024. Authentic Biochemistry Podcast
Biochemical Mosaic III. Inflamasomes c.11 A Dialectical Event Ontological conciliantus contrarion perspective.DJGPhD.3April24.Authentic Biochemistry Podcast.
Biochemical Mosaic III.c.10 Atherogenesis and neointma formation are associated with sphingomyelinase membrane raft NOX aggregation during inflammasome activation.DJGPhD.2April24
Biochemical Mosaic III.c.9 Clinical associations of inflammasome mediated pathophysiology linked to epigenetic methylation patterning and DNA repair. DJGPhD.1April24.
Biochemical Mosaic III.c.8. S. aureus clearance via dual pyroptosis and necroptosis salientsand the control over the hyperinflammatory axis of clinical disease. DJGPhD.31.3.24
Biochemical Mosaic III.c.7 Convergence of Inflammasome molecular patterning obtains PRR-like sequalae that are hypo-modified epigenetically in multple Human pathophysiologies
Biochemical Mosaic III. c.6. S auereus induced inflammasome activating pyroptosis circumvents immune clearance and ARDS pulmonary chronic activation share similar hyperinflammatory presentation.DJGPhD
Biochemical Mosaic III. c.5. Gal3 and NRLP3 inflammasome coordinate inflammation via IL-1Beta convertase activation that is associated with NAFLD and NASH and inhibition of ABCA1 cholesterol efflux.
Biochemical MosaicIII. C.4. My oppositional dialectic and episteme- metaphysical discourse on method+ Gal3 as proinflammatory lectin may not uniformly correlate with pathobiochemical events. DJGPhD.
Biochemical Mosaic III c.3. Bacterial glycosphingolipid mediated inflammasome activation and the Galectin:NLRP3 interaction pathophenocopy oxy-mtDNA TLR induction.DJGPhD.21.3.24
Biochemical Mosaic III. C.2 A Non-canonical autophagic inhibition of NLRP3 inflammasome mediated inflammation in UVB-treated human keratinocytes.DJGPhD. 20.3.24.
Biochemical Mosaic III. C.1. Inflammasomes. DJGPhD.19.3.24 Authentic Biochemistry Podcast
Biochemical MosaicII.Book2.C.13.Dialectical event ontologies involving CNS plasmalogen and sphingolipid interlocution and the universality of Mozart and the Beatles. DJGPhD.17.3.24.Authentic Biochem.
Biochemical Mosaic II.Book 2. c.12 Adduced mTORC mediated glycerol-sphingolipid enzyme mRNA transcriptome association with Plasmalogen apodiction of myelination.DJGPhD.16.3.24
MosaicII,Bk.2.c.11 Squalene monooxygenase (SM) stabilization due to plasmalogen pathway fatty acid reductase deficiency promotes SM epoxidase alternate activity thus lowering24OHCHOL-LXR-myelination.
Biochemical Mosaic II. Book2. c.10.Plasmalogen mediated oxy vs epoxy sterol synthesis may control cns inflammation and myelination given acid-catalyzed transacetalization sequalae.DJGPhD.12March24
Biochemical Mosaic II. Book2. c.9. Plasmalogen regulation of composite ruling over prescriptive organization of cellular-biochemical phenomena includes florid mediation of the CNS.DJGPhD.11MARCH2024.
Biochemical Mosaic II.c.8 Cell death and CE-circ RNA vs.miRNA in Hepatocellular carcinoma: the spectre of AGPS et al. DJGPhD. 10March24.Authentic Biochemistry.
Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem.
Biochemical Mosaic II.c.6 Meduloblastoma is linked to plasmalogen and circ RNA phenomena that are pathophenocopied in other cancers. DJGPhD.5.Mar24.Authentic Biochemistry
Biochemical Mosaic II. c.5 Peroxisomal plasmalogen biosynthesis may regulate transcriptomic and proteomic sequalae to plasmamembrane mediated signal transduction. DJGPhD.4March24.
Biochemical Mosaic II. c.4. Peroxisomal biogenesis and AGPS-mediated plasmalogen synthesis involve circular RNA species that alter microRNA and mRNA expression in human cancers. DJGPhD.3MAR24.
Saturday Night Authentic Biochemistry The Agentic operator as metaphysical metaphor in metabolic regulation. DJGPhD.2March 2024.
Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry.
Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24
Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast
A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast
Biochemical Mosaic I. CODA. Membrane lipids function as biosensors for pKa's of phosphonoester anionic charge density with polybasic protein domains to mediate communication including transcription.
Biochemical MosaicI.c.13 Phosphatidic acid as key lipid intermediary of membrane secretion signalling and cellular intracommunication via kinase cascade and transcriptional regulation.DJGPhD.22.2.24
Biochemical Mosaic I. c.12. The porosomal secretory system requires anioic lipids including phosphatidic acid. DJGPhD.21.2.24
Biochemical Mosaic I.c.11. Glycerolipid metabolism coupled to mTORC1 enzyme phosphorylation necessarily involves a complete analysis of membrane lipid molecular species distribution.DJGPhD.20.2.24
Biochemical Mosaic I c.10. Is PE depletion reversed by mTORC1 phosphorylation of LIPIN1 or is DAG authentically activating CCT via membrane association thus obtaining robust PL synthesis? DJGPhD.
Biochemical Mosaic I. c.9 Increased inner mitochondrial membrane PE from PS decarboxylase decreases protease mediated degradation of phospholipid transfer proteins thus maintaining fusion potency.
Biochemical Mosaic I PA-phosphatase c.8. Membrane fusion and the dynamics of mitochondrial reduction vs. proliferation; the PA phosphatase in lipid metabolism. DJGPhD. 16.2.24 Authentic Biochemistry
Biochemical Mosaic I. Phosphatidic acid Phosphatase. c.7. Mutational reversal of IDH1 leads to NADPH depletion concomitant with potent anti-PHD enantiomeric 2-hydroxyglutarate obtaining pseudohypoxia.
Biochemical Mosaic I. The PA phosphatase c.6. Alteration of the TCA pathway intermediates and hypoxia/nutrient deficiency control HIF1α stability indirectly regulating IMM protein and lipid turnover.
The Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.5. Tumor cells adapt bioenergetic fuel economy toward cell immortalization via re-crafting of mitochondrial IM lipid speciation.DJGPhD.12Feb24
Biochemical Mosaic I. Phosphatidic Acid Phosphatase c.4 GLN utilization and an IMM protease regulate mitochondrial involvement in cancer growth. DJGPhD. Authentic Biochemistry 10Feb24
Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. c.3 Indirect consequences of mitochondrial proteomic variation potentially obtains GLN-linked Warburg glycolysis preventing ROS.
Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. Autophagy commitment is linked to mTORC1 v. AMPK oppostional kinase networks maintaining proteostasis and lipid homeostasis.DJGPhD
Biochemical Mosaic Event Ontologies I. Phosphatidic Acid Phosphatase. Prologomena c.1.
BioMedical Portrait VIII. C.22 CODA. Microglial Leukotrienes in neurodegeneration.DJGPhD.04Feb2024. Authentic Biochemistry Podcast.
BioMedical Portrait VIII. c.21 Lysopholpids like sphingolipids hydrogen bond to cholesterol mediating lipid membrane raft mobility. DJGPhD. 2Feb2024. Authentic Biochemistry Podcast
BioMedical Portrait VIII C.20. Heterologous lipid sequence membrane domains rearrange according to LysoPL polarity after PLA2 mediated 20:4 removal and acetosalicylic acid alters fatty acid ordering.
BioMed PortraitVIII.c.19. Membrane thermotropic phase transition enthalpic responses to Leukotriene synthesis in relation to cholesterol and lysophospholipid fluid dynamics.DJGPhD.31.1.24.Authentic BC
BioMed Portrait VIII.c.18Aspirin PGS (COX) inhibited membrane topological and integrated molecular dynamics: leukotriene –cytokine mediated asthmatic inflammation.DJGPhD.29.1.24. Authentic Biochem.
Sententia non Fengo, concluding remarks. BioMedical PortraitVIII. (C.17). LTC4 and LTD4 interact with IL-33 inducing cytokine generation in lung ILC2s.DJGPhD.28.1.24
Sententia non Fengo: A minor prolegomenon to the purpose of Authentic Biochemistry. DJGPhD.28.1.24
BioMed Portrait VIII. c.16. Coordinated complimentarity of cell cycle MEK kinase cascade with the IL33-ST2 and CysLT1R mediatedILC2 activation to promote type 2 immunopathology. DJGPhD.25.1.24
BioMedical Portrait VIII.c.15. ILC associated hippocampal RNA-BP's exacerbate GLU neurotoxicity and regulate CysLT1R in lung ILC2's. DJGPhD. 23.1.24.
BioMedical Portrait VIII.c.14 The dialectical events between immune responses and leukotriene signaling are modulated by tissue-resident and circulating cell patterns via RNA binding proteins.DJGPhD.
BioMedical PortraitVIII.c.13 Leukotriene metabolism and reception is linked to innate like lymphocytes involved in airway inflammation and hyper-responsiveness-associated asthma.DJGPhD.19.1.24.AB.
BioMedical Portrait VIII.c.12. 5-LOX associates with FLAP and PLA2 at the nuclear envelope to trigger and control ILC2 mediation of the allergic asthma AHR pathology. DJGPhD 17.1.24. Authentic Bioch.
BioMedical Portrait VIII. C.11 Peptidyl leukotrieneR- mediated transcription of PTGS2and LOX15B with IL4/IL13 and IL33 in asthmatic lung airway constrictionin MDM's LM's and ILC2's DJGPhD.16.1.24
BioMedical Portrait VIII. c.10. The LOX5 and LOX12/15 pathways for 20:4, 20:5 and 22:6produce over 50 unique molecular species of oxylipins and lipoxins with unique biological sequalae.DJGPhD.14.1.24.
BioMedical Portrait VIII. c.9. Initial detail of the LOX vs.COX isoform utilization of essential and other dietary PUFA's in complex leukotriene biosynthesis. DJGPhD.11Jan24.Authentic Biochemistry.
BioMedical Portrait vIII. Leukotrienes. c.8 Leukotriene regulated Heterodimer Nuclear Receptor transcription factors organize around complex multi-ligand binding and sojourner molecular modifiers
BioMedical Portrait VIII.c.7. Differential control over fatty acid oxygenation and PPAR/RXR heterodimer pairing in mammalian uterine cell estrus physiology.DJGPhD.8Jan2024
EtOH Membrane Intoxication c.3. Epiphantei: ethanol-induced membrane degeneration results in altered porosity/tortuosity dynamics and microglia-failed tissue surveilance/repair in the CNS.DJGPhD.
EtOH c.2 Mean diffusivity and tortuosity metrics in ethanol induced white matter lesions.
BioMedical Portrait VIII.c.6 Precursor 20:4 5,8,11,14 derived prostaglandins and leukotriene roles in PPAR and RXR transcription factor expression in mammalian reproductive tissues. DJGPhD. 04JAN24.AB
Post Holiday EtOH Lectures. Volume One. Dr. Daniel J. Guerra. 01Jan2024. Authentic Biochemistry
BioMedical Portrait VIII.c.5 Leukotrienes. Lipoxygenase isoform mediated control over resident tissue macrophage speciation.Dr Daniel J. Guerra. 01Jan2024. Authentic Biochemistry Podcast
BioMedical Portrait VIII. c.4 A deft-handed apprehension of chirality to facillitate reasoned appreciation of leukotriene molecular heterogeneity.DJGPhD. 30.12.23. Authentic Biochemistry.
BioMedical Portrait VIII.c.3. Leukotriene molecular speciation involves subcellular re-distribution of modifying enzymes and adaptor proteins associating with ER and Nuclear membranes.DJGPhD.28.12.23
BioMedical Portrait VIII.c.2 Leukotrienes: regio-associated oxygenation patterns of lipoxins and peptido-LTC's distrubute among pro-inflammatory states . DJGPhD. 27.12.23. Authentic Biochemistry
BioMedical Portrait VIII. c.1 Leukotrienes: an Introduction. Dr Daniel J. Guerra. 26.12.23 Authentic Biochemistry Podcast.
Christmas Eve Special:Research science relies on the means by which it is apprehended thus continuously challenged and improved with the goal of finding truths about nature in perpetuity.DJGPhD
Dyslipidaemia Coda IV. Antinomies and paralogisms in discerning apoplipoprotein contribution to HTG vs.CAD. DJGPhD.21.12.23.Authentic Biochemistry.
Dyslipiaemia Coda III. The proposed use of apolipoprotein serum concentration and hyperTAG may require a deeper analysis at the transcriptomic and proteomic levels. DJGPhD.20.12.23 Authentic Biochem.
DYSLIPIDAEMIA CODA II. Hypertriacylglycerolaemia is linked to mutations in LPL and various apolipoproteins linking CAD to TAG. 18.12.23. DJGPhD.Authentic Biochemistry
BioMedical Portrait VII. C.7. Lipoprotein biosynthesis and apolipoprotein structure. DJGPhD. 16.12/23. Authentic Biochemistry
BioMedical Portrait VII.c.6 Lipoprotein Lipase regulation performs a critical role in lipid homeostasis as evidenced by chylomicron clearance resistance in obese dyslipidaemic adolescents and adults.
BPVII.c.5 Diminished circ.LPL and adiponectin in obese adolescents correlates with higher dyslipidaemic T2D, MetSynD, and insulin resistance via inflammation-triggering lipoprotein non-clearance.
BioMedical Portrait VII. C.4 Chylomicron associated endothelial luminal LPL differential interaction with ANGTPL isoforms reults in unique TRL disposition. DJGPhD.10Dec23
BioMedical Portarit VII. c.3. Introduction to chylomicron apoB48 and the angiopoietin-like LPL inhibitor contributions to circulating TAG. DJGPhD.9DEC23. authentic Biochemistry
BioMed Portrait VII. c.2 Lipoprotein lipase mediated TAG delivery and adolescent obesity. DJGPhD.6Dec23. Authentic Biochemistry
BioMedical Portrait VII. Lipoprotein Lipase Pathobiochemistry. Prolegomena. DJGPhD. 5Dec23 Authentic Biochemistry
Bio Med Portrait. c.16. NK cells promote the inflammatory court in NAFLD via mutations in lipid metabolism and excessive GK mediated glycolysis and lipogenesis in hepatocytes DJGPhD.3Dec23b
BioMed Portrait VI.C.15 Characterization of four lipid and glucose metabolic polypeptides linked to obesity/T2D and NASH-->HCC.DJGPhD.3Dec23.Authentic Biochemistry Podcast
BioMedical PortraitVI.C.14.Liver NK cell chemokine recruitment and the significant role of obesity in possible immunotoxicity in HCC ontogeny.DJGPhD.30.11.23
BioMedical PortraitVI.c.13. Senescense and the aging of cells within systems apprehends the event ontologies of the stress phenomena-immune surveillance axis.DJGPhD.29.11.23. Authentic Biochemistry.
BioMedical Portrait VI. c.12. Obesity and viral infection-associated NK malfunction may lead to NASH and subsequent HCC. DJGPhD.28.11.23. Authentic Biochemistry
BioMedical Portrait VI. c.11 NK cell involvement in HepatoCellular Carcinoma. DJGPhD. 26.11.23. Authentic Biochemistry
"The Universe by Negation" DJGPhD.23.11.23
BioMedical Portrait VI.c.10.Alterations in the cytotoxic immune response can be dissociated from inflammation via intermediary metabolic mutation.DJGPhD.22.11.23. Authentic Biochemistry Pootdcast.
BioMedical PortraitVI.c.9 HLH mutations obtain complex NKvs.CD8+ T cell alterations in cytototoxicity and proliferation.DJGPhD.21.11.23 Authentic Biochemistry.
BioMedical Portrait VI.c.8.The cytotoxicity of the NK cell Is a function of its bioenergetics. Glycolysis/OXPHOS vs. FAO/OXPHOS during activation/proliferation
BioMedical PortraitVI.C.7 IEI/IEM pathobiochemistry involves bioenergetics, transcriptional , translational, and post-translational modification sequalae.DJGPhD.19.11.23 Authentic Biochemistry.
BioMedical Portrait VI c.6.Hemophagocytic lymphohistiocytosis ACAD9/Rab27A/+/- FBase1 mutations linked to NK and CTL immunodeficiences.DJGPhD. 16/11/23. Authentic Biochemistry.
BioMed Portrait VIc.5. NK cell Inborn Error Of Immunity links to failed fatty acyl CoA dehydrogenase-obtained immunodeficiency.DJGPhD. 15.11.23. Authentic Biochemistry
BioMedical Portrait VI.c4. Tumor and DC antigen VAX directed melanoma therapy reveals CD8+CTL and NK cell surface population dynamics.DJGPhG.14.11.23. Authentic Biochemistry.
BioMedical PortraitVIc.3. NK cell phenotypic variation is tighly regulated to facillitate unique immune sequalae including tumor ablation, pathogen elimination and autoimmunity.13.11.23.DJGPhD
BioMedical ortrait VI. Development of a dendritic cell antigen presenting melanoma kinase derived vax targeting NK cells to ablate malignancy.DJGPhD.11NOV23
BioMedical Potrait VI. Natural Killer Cells: opening remarks. DJGPhD.9NOV23. Authentic Biochemistry
BioMedical Portrait V. Coda c.13 Small molecule pyrazolo-oxazepine derivitive mediated PFK-1 activation depletes NADPH dependent neutrophil oxidative burst. DJGPhD.07NOV23. Authentic Biochemistry
BioMedical Portrait V.c.12. Is there a compositional-sequential event ontology linking "moonlighting"c-Fos with NOX2 PX domain PIP3 binding?DJGPhD. 6NOV23
BioMedical Portrait V.c.11 The Phosphoglycerolipid metabolome that orchestrates membrane topology and surface chemistry that supports necessary protein association for neutrophil immunoresponses.
BioMedical Portrait V.c.10. Phosphphatidyl inositols and phagosmal genesis in activated neutrophils upon pathogen infection.
BioMedical PortraitV.c9. Both glycolytic and OPP regulation combine complex allosteric and amphibolic sequalae that may converge on an immune- hyperinflammatory state. DJGPhD.2NOV23.
BioMedical Portrait V.c8. NOX2 subunitorganization, oxygen availability and phase I discussion of glycolytic allosteric control.DJGPhD.01Nov23
BioMedical Portrait V C.5 Periodontitis-linked CVD. DJGPhD. 30.10.31
BioMedical Portrait V. c7. NETs and the combined activities of elastase,NOX2,MPO and IP3 PTEN phosphatase potentiate inflammation-linked pathologies of lung and pancreas. DJGPhD.31.10.23 and
BioMedical Portrait V C.6 P. gingivalis Two Component System assembly and activation mediate infection court involvement in subsequent host vector pathology.DJGPhD. 30.10.23b.
BioMedical Portrait Vc4 Two component signal system pathogenic bacterial responses to host immunity and the gigipain cysteine protease opposing serum secretory IgA mediated phagocyte activation.DJGPhD
BioMedical Portrait V.c3. The categorical analysis of Neutrophil involvement in multiple pathophysiologies requires cellular signaling to derivatize pleiotropic disease ontologies. DJGPhD.26.10.23
BioMedical Portrait V. The neutrohil oxidative burst and the roles of Phox generating superoxide and peptide arginine deiminase in phagocyte defense against pathogens and contrarion disease promotion.
BioMedical Portrait V. Introductory alethic unfolding of neutrophil glycolysis associated hyperinflammatory restraint.
Continuing dialectical event ontology of epistemological requirements for validation of biochemical research. DJGPhD.23.10.23. Authentic Biochemistry Podcast
All reciprocity in not disinterested so phenomena must be in equilibrium. But phenomena at equilibrium are invisible so reciprocity must be uncertain. DJGPhD.22.10.23. Authentic Biochemistry
BioMedical Portrait IV. Postcript DJGPhD. 21 October 2023. Authentic Biochemistry Podcast
BioMedical Portrait IV. 13b. Magnetic Resonance Imaging as a non-invasive tool in Neurodegenerative Diseases. DJGPhD.19.10.23 Authentic Biochemistry.
BioMedical Portrait IV. CODAIII. c13. Microglial and astrocytic CNS local neuronal environment temporality may apprehend FTD stages in the human CNS.DJGPhD.18.10.23. Authentic Biochemistry Podcast
BioMedica; Portrait IV Coda II.c12. Biochemical Concatenations-the spatiotemporal sequences of molecular-cellular events of FTD's from proteinopathies to signalling and antigen recognition. DJGPhD.
BioMedical Portrait IV c11. FTLD-tau is correlated with microglial and astrocytic inflammation and subsequent neural degeneration. DJGPhD. 16.10.23 Authentic Biochemistry.
BioMedical PortraitIV The Frontal Temporal Dementias. Tau and TDP43 proteinopathies as an introduction to the extended pathobiochemical event ontologies. DJGPhD.16.10.23.Authentic Biochemistry Podcast
BioMedical Portrait IV. TDP43 is involved in numerous pathologies that connect to the major cellular mechanisms governing DNA RRR, RNA metabolism and protein mediated cell fate. DJGPhD.14.10.23
BioMedical Portrait IV c8. Proteolytic processing of cytosolic RNA-bp ,TDP43, associates with CNS neuropathologies while native nuclear translocation is linked to exon shuffling. DJGPhD.12Oct23.
BioMedical Portrait IV c7.Progranulin associated frontotemporal lobar degeneration and AD, PD, and LBD, share a TDP-43 proteinopathy linked to mRNA translation. DJGPhD.11OCT23. Authentic Biochemistry
BioMedical Portrait IV. c6. Proteinopathies in neurodegeneration may be the result of insufficient temporal control over microglial phagocytic and pro-inflammatory molecular event ontologies.DJGPhD
BioMedical Portrait IV.c5. Microglial removal of lipoprotein and proteinopathic molecular events must include lysosomal degradation and antigen presentation while supporting signaling and inflammation
BioMedical PortraitIVc4. Microglial Rho GTPases equipped with GGylation, palmitoylation and/or phosphorylation obtain a spectrum of biochemical functions in neuropathologies.DJGPhD.8Oct23b. Authentic.
BioMedical Portrait IV. c3. Two down-regulated microglial polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy distinct LDL binding proteins typically cargo oxy cholesterol.
BioMedical PortraitIV.NHD patient fibroblasts used to generate iPSC's differentiated into Induced microglia like cells (iMGLs) pathophenocopied TREM2 mutations and lysosomal malfunctions.DJGPhD.
BioMedical Portrait IV. HLA disease including neuropatholgies. The Nasu-Hakola, a.k.a. polycystic lipomembranous osteodysplasia associated TREM2 disease. DJGPhD.04Oct2023.Authentic Biochemistry.
BioMedical PortraitIIIC13c. Leucocyte and lymphocyte mediated SASP involve a corruption in robust novel immune responses while enhancing chronic autoimmune inflammation in the obese and elderly.DJGPhD
BioMedical PortraitIII. c13b.Immune cell metabolic dialectical usurpation of architechtonic control over inflammation and cell fate obtained from senescence and obesity.-linked dyslipidaemia.DJGPhD.
BioiMedical Portrait III. NLRP3 Inflammasome and senescence-associated heterochromatic foci in macrophages, Kuppfer Cells and Liver sinusoidal endothelial cells contibute to liver/adipose disease
BioMedical Portrait III.c12. Senescent cells from aging and obesity obtain chronic hyperinflammation of adipose associated leucocyte infiltrates potentiating alternating systemic proliferation or PCD.
BioMedical Portrait III. AMPK regulation of ACC2 blocks MalCoA inhibition of CPTI allowing for fatty acid beta oxidation thus alleviating adipose obesity-induced macrophage pro-inflammation.DJGPhD.
BioMedical Portrait III. c10. Ribosomal collision frequency is attenuated by ZAK and GCN2 via mutually exclusive signalling events, DJGPhD. 25.9.23. Authentic Biochemistry Podcast
BioMedical Portrait III. c9. Amino acid deprivation-linked fall of polypeptide synthetic fidelity triggers downstream ribosomal stress response phenomena including kinase mediated cell fate sequalae.
BioMedical Portrait III. c8. Unique mRNA upstream open reading frames direct both the integrated stress response and rare selective up-regulation of stress-correcting protein synthesis.DJGPhD.21.9.23
BioMedical Portrait III.c.7 Elementary polypeptide synthesis-translation. Lecture 1. DJGPhD.20.9.23.Authentic Biochemistry Podcast.
BioMedical Portrait III. c6. Adipokine and the succinate receptor systems in obese adipose inflammation as regulated by AMPK.DJGPhD.19.9.23. Authentic Biochemistry Podcast
BioMedical Portrait III.c.5. Adipokine mediated adipose inflamation is linked to the hypothalamic control over metabolism and systemic inflammation.DJGPhD.18.9.23.Authentic Biochemistry Podcast
BioMedical Portrait III. c.4. Adipose tissue macrophages express galectin binding proteins which alter immunosuppression and polarization;adipokines mediate the inflammatory response. DJGPhD.17.9.23
BioMedical Portrait III. Immunometabolic disease 3c.Reactive N and O interconversions in obese adipose exacerbate systemic inflammation. 17.9.23. DJGPhD. Authentic Biochemistry Podcast.
BioMedical Portrait III. Immunometabolic disease. The obesity-compromised adipose poise to hyperinflammation. DJGPhD. 15.9.23. Authentic Biochemistry.
BioMedical Portrait III. c1. Immuno-metabolic disease. Dr. Daniel J. Guerra. 14.9.23. Authentic Biochemistry Podcast.
Biochemical Energetics. Elementary Considerations chapter2. DJGPhD. 13.9.23 Authentic Biochemistry Podcast
Biochemical Energetics I Elementary Considerations. DJGPhD 12Sept23. Authentic Biochemistry Podcast.
BioMedical Portrait II. Hashimoto's Thyroiditis prevalence in women linked to mitochondrial electron transport chain activity, ATP/ADP translocation, and potent autoantibodies to thyroid peroxidase.
BioMedical Portrait II. c.14. Predominance of Hashimoto's Thyroiditis in Women: is there a link to the decreased expression of TLR7 and the AMPK-alpha/Id3 axis on CD8+TE and Treg activity?
BioMedical PortraitII. c13. Female prevalent autoimmune RA-macrophage STAT3(TF) and NaMPT(NAD+ salvage pathway) promote rheumatoid arthritis & primer on thyroiditis
BioMedical Portrait II. C12. Lupus is far more common in women than men due to TLR7 enhancement and Rheumatoid Arthritis is more common in women due to macrophage bioeneregtic phenomenaDJGPhD.7Sept23
BioMedical Portrait II.c11. Autoimmune diseases like lupus are far more prevalent in women due to the lack of X chromosomal allelic inactivationof TLR7's. DJGPhD.7Sept23.Authentic Biochemistry.
Biomedical Portrait!!,c.10 Older women have more reactive oxygen and fewer functional mitochondria and DNA content than older men or younger women.DJGPhD.5Dept2023. Authentic Biochemistry Podcast.
BioMedical Portrait II. c9. Autoimmune diseases are more common in women than men: immune response triggering and the possible role of bioenergetics.DJGPhD.3sept23.Authentic Biochemistry.
BioMedical Portrait II. C.8. Alterations in sphingosine metabolism linked to breast cancer staging in women and progression of NAFLD to NASH and HCC is much lower in women until menopause.DJGPhD.
Biomedical Portrait II. C.7. Serum sphingolipid molecular speciation in women differs from men but association with tissue endomembranous lipid components fail to be addressed.DJGPhD. 31.8.23
BioMedical Portrait II. Metabolic and Bioenergetic distinction between men and women includes lipid deposition and utilization mechanisms.DJGPhD.30.8.23.Authentic Biochemistry Podcast.
BioMedical Portrait II, c.5. Muscle fibre sexual dimorphism obtains networks of genetic, epigenetic, and biochemical events.DJGPhD.29.8.23 Authentic Biochemistry Podcast
Biomedical PortraitII.C.4 THe sexual dimorphism of bioenergetics: introduction to carbon utilization. Video lecture link
BioMedical Portrait II. Chapter 3. Mitochondrial gene expression, lipid metabolism and cell fate are at least partiatially mediated by Fragile X protein competency. DJGPhD.24.8.23
BioMedical Portrait II. The Fragile X Syndrome. Discovery and subsequent association with the FMR1 gene. Premature Ovary Failure I vs. heritable intellectual disabilities DJGPhD.22.8.23
BioMedical Portrait II.Diseases of Bioenergetics:Male vs. Female Variation
BioMedical Portrait I. 13b. 25 hydroxy cholesterol controling SREBP is linked toinflammation and the regulation of potentiating estrogen mediation over AD in post menapausal women.DJGPHD.18.8.23
Biomedical Portrait I, 13. Receptor boud 17Beta-estradiol may overturn the the failure to synthesize cholesterol in CNS caveolae thus blocking release of Beta-secretase to generate A-beta from APP.
BioMedical Portraits I. Chapter 12. Unique lipoprotein lipase mediated lipid alteration of endothelial cell function in the mammalian CNS may traffick in oxysterol binding protein linked PM-female AD
BioMedical Portraits I. [11]. Phospholipid and lipoprotein lipase activity may link to oxy-cholesterol/PL transport mechanisms to generate post-menopausal AD. DJGPhD.16.8.23. Authentic Biochemistry
BioMedical PortraitI-10. Sterol binding protein and oxysterols regulate membrane fusion and trafficking obtaining a complex landscape for post menopausal estrogen assoc. neurodegeneration.DJGPhD.
BioMedical PortraitsI.9. The 27-hydroxychol association with estrogen receptors and LXR provide contrarion associations with female AD and immune-controlled bacterial pathophysiology.DJGPhD.14.8.23
BioMedical Portrait I. Chapter 8. Female AD progression post-menopausal severity is a complex pathobiochemical event that may involve cholesterol and steroid metabolism in the CNS and periphery.DJGPhD
BioMedical Portraits I. Chapter 7. Hormone replacement and the general distinctions of cholesterol homeostasis, metabolic zonation, hydroxysterols and estrogen receptor heterogeneity in female AD.
BioMedical Portraits I. Chapter 6. Complications of female cerebrovascular trauma and obesity-linked Type2 Diabetes in post-menopausal estrogen therapeutics for prophylactic treatment of subsequent AD
Biomedical Portraits I. Part 5. 17-beta estradiol monotherapy in post-menopausal women has no irrefutable therapeutic benefit for treating cognitive decline in early AD dementia.DJGPhD.8AUG23.AB.
BioMedical Portraits I. Part 4 Loss of female gonadal E2 production plus CNS E2 Receptor expression post-menopause involves irreversible alterations in metabolism:implications for neuroprotection.
BioMedical Portraits I. part 3 Estrogen receptor heterogeneity in signaling and transcription and the distinctions between model-murine and human reproductive and CNS biochemistry.DJGPhD 05AUG23
BioMedical Portraits I. Part 2.Murine model Alzheimer's Disease is poorly linked to menopuase or Vascular contributions to Cognitive Impairment & Dementia (VCID).DJGPhD 05AUG23
BioMedical Portraits I. Alzheimers Disease in Ageing Females is linked to CNS-sphingomyelinase mediated ketogenesis and VCID.Lecture 1. DJGPhD.3AUG23.Authentic Biochemistry
From Intellections' pathway into the forest of metaphysics.II DJGPhD.30.July 2023b. Authentic Biochemistry Podcast
The Road to Intellection I. DJGPhD. 30.7.23. Authentic Biochemistry Podcast
ImmunoEpigenetics 100B. Fine. The apodictic recombination-dependent TCR and Ig receptor system is mediated by epigentic modifications.DJGPhD.29.7.23. Authentic Biochemistry
ImmunoEpigenetics100A. The Tcell repose and ILC differentiation via E vs ID chromatin remodeling antagonism. DJGPhD.28.7.23. Authentic Biochemistry Podcast.
ImmunoEpigenetics 99. Tregs can foster a massive tumor microenvironment inhibition of T-eff cell populations via neo-antigen activation from dying tumor cells leading to cancer progression. DJGPhD
ImmunoEpigenetics 98. TCR mediated protection from neonate infection is naturally suppressed. BCG VAX may be a treatment against Type 1 Diabetes by increasing Treg mediated autoimmune suppression.
ImmunoEpigenetics97.Bcell maturation involves a multilevel epigenetic mark-up of differentiating pathways to subsequently respond to T cell activation upon 2nd signal stimulation. DJGPhD.24.7.23
ImmunoEpigenetics96. APC-agMHCII and Bcell:Tcell synapse interactions yield subsequent plasma cell antibody production under the H3K4me3 epigenetic alteration of chromatin accessibility.DJGPhD.23.7.23
Mountain Pass Adventure I. The "five best" and an excursion into asymmetry. Dr. Daniel J. Guerra. 22.7.23. Authentic Biochemistry Podcast.
ImmunoEpigenetics 95. Does H3K4 trimethylation play a quantitative or qualitative role in nascent activation of neonatal naive T cells toward a specific polarity of gene expression?DJGPhD.20.7.23
ImmunoEpigenetics. 94. Neonate TCR stimulation and subsequent signaling circumventing TCR specificity differ from adult activation and cytokine expression. DJGPhD. 19.7.23. Authentic Biochemistry
ImmunoEpigenetics 93. tTREG's not only control Th differentiation and proliferation but in an HLA-antigen mediated specificity thus differentiating CD4+ vs CD8+ inflammation as directed by 6mA.
ImmunoEpigenetics 92. thymic Treg populations alter Th1 differentiation. Antigen presenting DC's coordinate TCR with associated membrane proteins to support activation via PM lipid sequence.DJGPhD.
ImmunoEpigenetics91. WTAP conditional deletion via LoxPCre controlled by FoxP3 obtains a Treg phenotype incapable of supressing murine spontaneous colitis. DJGPhD. 15.7.23. Authentic Biochemistry.
ImmunoEpigenetics90. Tcell receptor organization activation and adaptor protein ligand molecular signaling is regulated down stream by 6methyl mRNA speciation.DJGPhD.7July2023.Authentic Biochemistry
Enzyme Kinetics sensu strictu. The Michaelis Menten equations and precison of the kcat. DJGPhD.9July23b. Authentic Biochemistry Podcast.
Primer on enzyme kinetics in clinical biochemical research. DR. Daniel J. Guerra. 09July2023. Authentic Biochemistry Podcast Productions
PhotosynthesisV. Photorespiration and synthesis of this holiday arc: fait accompli. DJGPhD.08July23b. Authentic BiochemistryPodcast.
Photosynthesis 4. Chlorophyll and carotene biosynthesis and some further detail on the mechanism of the Mn-H20 splitting complex of p680 PSII and diatomic molecular oxygen (O2) evolution.DJGPhD. 7July
Photosynthesis 3. Dr Daniel J Guerra. 07July2023 Authentic Biochemistry Podcast productions
Unique Lecture Post holidayIV. Photosynthesis 2. DJGPhD.05July23b Authentic Biochemistry Podcast production.
Unique Lecture Series Post holiday. III Higher plant photosynthesis 1. DJGPhD. 05July2023. Authentic Biochemistry Podcast.
Unique Lecture Series Holiday Time 4th of July2023.Non-arbitrary C-C bond formation chemistry: Aldol and Claisen condensation with Stork enamine synthesis (i.e. Michael reactions)
Unique Lecture Series . Holiday Time. 4th of July 2023! Hydrocarbons.
ImmunoEpigenetics 89. Final synthesis of statin drug mediated alteration of metabolism in T lymphocytes. DJGPhD.6.30.23. Authentic Biochemistry Podcast.
ImmunoEpigenetics 88. Statin treatment of early progenitor T cell acute lymphoblastic leukemia could pose biochemical impositions on healthy lymphocyte populations. DJGPhD.29.6.23.Authentic Biochem.
ImmunoEpigenetics87. Competitive inhibition of HMGCoA-R may enhance apoptosis while blocking cholesterologenesis and GGPP covalent modification of signaling kinases to thwart ETP-All in cell culture.
ImmunoEpigenetics86. Could regimented titrating statin pharmacotherapy be useful in controlling early T lymphoid progenitor cell ETP-ALL via an epigenetic mechansim? DJGPhD.27.6.23. Authentic Biochem
ImmunoEpigenetics85.Epigenetic plasticity-induced chromatin retailoring involving the mevalonic acid -prenyl lipid pathway promotes Early T-cell Precursor Acute Lymphoblastic Leukemia. DJGPhD.24.6.23
ImmunoEpigenetics84. T cell and ILC transcription factor and cytokine signaling coordination to accelerate a combined innate/acquired immune response requires discrete epigenetic programming. DJGPhD.
ImmunoEpigenetics 83. Epistemic and metaphysical considerations of immune cell epigenetic reprogramming obtaining biochemical event ontologies. DJGPhD.23.6.23. Authentic Biochemistry Podcast
ImmunoEpigenetics82.Innate lymphoid progenitor antibody-directed single cell DNAse hypersenitive site analysis of transcription factor specific histone methylation and acetylation modifications.DJGPhD
ImmunoEpigenetics 81.Innate lymphoid cells lack antigen receptors and are differentiated into multiple linneages via epigenetic priming of nucleosomal regions proximal to cell-specific TF's.DJGPhD.
ImmunoEpigenetics80.T lymphocyte biochemical communications are triggered epigentically and via membrane lipid molecular species recombination: A dialectical event ontological view. DJGPhD.17.6.23
ImmunoEpigenetics79. T lymphocyte DPPA induced HSP27 deoligomerization-activating DGK-a associated anergy is linked to cancer cell proliferation phenotypes. DJGPhD.16.6.23b Authentic Biochemistry
ImmunoEpigenetics 78. Classical ergodic forward deterministics do not explain biological systems; biochemical phenomena are tuned for uncertain events. DJGPhD.16.6.23. Authentic Biochemistry Podcast
ImmunoEpigenetics77. T cell membrane phospholipase D mediated PA deprotonation as a biosensor for an electrostatic/hydrogen-bond signal transductionDJGPhD.15.6.23. Authentic Biochemistry Podcast.
Interum lecture VI. Entropic forces and the ergodic hierarchy of GPCR-linked phsopholipase phase space postioning temporality. DJGPhD.13.6.23
Interum Lecture V. Semi-closure on free energy and enthalpic involvement in leptin/AMPK mediated orexigenic states . DJGPhD.12June23.Authentic Biochemistry Podcast
Interum Lecture IV. MBD:DNAMolecular Dynamics video lecture!
Interum Lecture III. Protein methylation binding domain association with substrate CpG alters equilibrium torsion angle (epsilon-zeta) conformational states via enthalpic-free energy conservation.
Interum Lecture II. Rates of reactions in living systems.DJGPhD.8June2023 Authentic Biochemistry Podcast
Interrum lecture I. Obesity unsuccessfully violates the first law of thermodynamics.
ImmunoEpigenetics 76. Sphingolipid metabolism and S1P receptor expression linked to multiple potentiating immunoinflammatory obese associated pathophysiologies. DJGPhD.6June23B AuthenticBiochemistry
ImmunoEpigenetics 75. Sphingolipid receptor molecular discernment from exosome cargo mediated control involves M1 to M2 polarization shift post myocardial infarction induced fibrosis. DJGPhD.6June23
ImmunoEpigenetics74.The methylation-specific epigenetic control over adipose tissue macrophage polarity is axially supported by leptin induced CNS control over satiety and pancreatic insulin secretion
ImmunoEpigenetics 73. The dialectical synthesis of adipose PPAR-gamma mediated fatty acid binding protein4 expression in foam cell formation and subsequent adipokine contribution to insulin secretion
ImmunoEpigenetics72. Chemistry of reactive oxygen/nitrogen radical species as adipose pathobiochemical sequalae to obesity via M1 macrophage polarity involving adipose and vasculature pathophysiology.
ImmunoEpigenetics 71. Insulin receptor corruption is mediated by high circulating fatty acids, in situ DAG-PKCepsilon induced phosphorylation and membrane protein aggregation in obese diabetics.DJGPhD
ImmunoEpigenetics 70.Obesity-linked adipose resident macrophage (M1)polarization meta-inflammation leads to Insulin Resistance via fatty acid oxygenation in situ. DJGPhD.01June2023.Authentic Biochem.
Intermediary Metabolism Lecture. Covalent modification of enzymes and transcription factors alter bioenergetics and the pro-inflammatory response in obese vs. healthy patients.31.5.23 DJGPhD
See the youtube video in the show notes
ImmunoEpigenetics 69. Lipoprotein and cargo cholesterol in the epigenetic regulation of the tumor microenvironment secreted pleckstrin convertase corrupting CD8+ Tcell cholesterol uptake and potency.
Graduate Biochemistry Lecture III. Dietary lipid control over neuroendocrine system involves multiple organ systems in contact with immune surveilance. DJGPhD. 24.5.23B Authentic Biochemistry
Graduate Biochemistry Lecture.II. Lipid digestion and enterocyte localized neuroendocrine secretion proximal to chylomicron assembly.Dr Daniel J. Guerra. Authentic Biochemistry Podcast 19.5.23.
Special Graduate Biochemistry Lecture! Lipoproteins I. Dr Daniel J. Guerra. Authentic Biochemistry Podcast 19.5.23.
ImmunoEpigenetics 68. Closure on atherosclerosis and CVD linking transcription factors and membrane receptors to oxidation of PUFA's and oxysterol resulting in methylation of ABCG and SREB promoters
ImmunoEpigenetics 67. Pathobiochemical alteration of cholesterol oxides mediated via cytochrome P450 and dehydro -reductases link atherosclerosis and the CTX/SLO motor neuron diseases. DJGPhD
ImmunoEpigenetics 66. The NOX/PHOX/DUOX enzymes in atherosclerosis, thyroid hormonogenesis and thyroid tumorigenesis. An epigenetic telos from oxidized lipid to altered transcription patterns.DJGPhD.
ImmunoEpigenetics65. 7-keto-cholesterol-induced miR-144 transcription inhibits IDH2 translation lowering NADPH required for NO synthesis to maintain endothelial function leading to atherosclerosis.
ImmunoEpigenetics64. IDH1/2 ad Malic enzymes 1/2/3 may generate NADPH thus driving removal of ROS while simultaneously promoting atherosclerosis and tumorigenesis via epigenetic and bioenergetic means
ImmunoEpigenetics63. Amino acid metabolism is linked to DNA methylation via glycolytic intermediates and redox poise to expose neomorphic /antimorphic IDH1/2 transformation generating oncometabolites
ImmunoEpigenetics62.Macrophage "training" and T cell activation are epigentically controlled by moonlighting glycolytic and amino acid metabolic enzymes generating enantiomers of 2-OH glutarate.DJGPhD
ImmunoEpigenetics61. The role of leucocyte and lymphocyte aerobic glycolysis and bioenergetic trafficking between cytosol and the mitochondria mediating nuclear epigenetic substrate availability.
Immunoepigenetics 60. LOH of PHLDA3 confers wt allelic methylation and loss of activity in pancreatic neuroendocrine tumorigenesis. DJGPhD.7May23 Authentic Biochemistry Podcast
ImmunoEpigenetics59. The P53/AKT/PHLDA3 axis over tumorigenicity is controlled by endomembraneous targeting via glycerol lipid PhosphatidylInositol bis-phosphate (PIP2) phosphorylation to PIP3.5.12.23
ImmunoEpigenetics 58. Epigenetic mechanisms role in Loss of Heterozygosity (LOH) in TSG's advancing targeting of solid tumors via pharmacotherapeutic CAR-T cells. DJGPhD 27.4.23. Authentic Biochem.
ImmunoEpigenetics 57. Plasmacytoid dendritic cell neoplasias and the CAR-T cell tumor microenvironment exposure altering epigenetic TF regulation leading to diverse differentiation. DJGPhD.20.4.23
ImmunoEpigenetics 56. Dendritic cell immunobiochemistry introductions. DJGPhD. Authentic Biochemistry 15.4.23
ImmunoEpigenetics55. ILC and Treg differentiation is mediated by acetylation and methylation epigenegtic authorship at discrete TF binding site domains.DJGPhD.14.4.23. Authentic Biochemistry
Immunoepigenetics 54. Macrophages, T lymphocytes and neutrophils each comply with epigenetic alterations to mediate the inflammatory response. DJGPhD.12April.2023.Authentic Biochemistry
ImmunoEpigenetics 53.The metaphysics of biochemical control within epigenetic alteration of gene expression as obtained in macrophage mediated immune activation. DJGPhD.7April23'Authentic Biochem
ImmunoEpigenetics 52. Integration of intermediary metabolism with epigenetic modification of immune cell activation and proliferation.DJGPhD. 5April23. Authentic Biochemistry Podcast.
ImmunoEpigenetics 51. The Glutamine contribution to tumor bioenergetics and lipogenesis and the role of storage TAG in macrophage pro-inflammation. DJGPhD. 29.3.23
ImmunoEpigenetics 50. Malic Enzyme serves as a cytosolic circuit to generate pyruvate from glutamine to drive cancer cell division by altering TCA flux and indirectly, cell cycle progression.DJGPhD
ImmunoEpigenetics49.SiRNA knockdown of ME1 increases Haeme Oxygenase activity in both glucose supplemented and deprived cancer cells. The Pseudoparadox of epigenetic control over metabolism. DJGPhD
ImmunoEpigenetics48. Importance of malic enzyme isoform subcellular distribution using 13CNMR -U13C C6 glucose isotopomer detection of pathway intermediates:GSIS vs. cancer.DJGPhD.21.3.23
Immunoepigenetics 47. Intermediary metabolism re-enters the discussion on tumor corruption of cell division via diversion of glucose to NADPH production.DJGPhD
ImmunoEpigenetics 46.The Keap1/Nrf2/MAF axis in colorectal cancer: Methylation specific promoter mediated expression of anti-oxidant genes unveiling a complex role in tumorigenesis.DJGPhD.15.3.23
ImmunoEpigenetics 45. Innate immune cell nSMASE generates ceramide mediated TLR signalling epigenetic alterations resulting in COX-2 electrophile PG- Michael adduct removal of KEAP/Nrf2 association.
ImmunoEpigenetics 44. Ceramide and NRF2 mediate oxygen stress and the pro-inflammatory cytokine respose via association with chromatin epigenetic retailoring. DJGPhD.8March23. Authentic Biochemistry.
ImmunoEpigenetics XXXXIII. In silico analysis of Rheumatoid Arthritis methylation patterns fails to obtain a general rule for epigenetic regulation of gene expression.DJGPhD07March23. ABPe
ImmunoEpigenetics XXXXII. T-ALL Homeobox A gene alteration of MEF2C expressional variation linked to T-cell differentiation blockade as regulated by CaMK and HDAC4/HDAC5. DJGPhD. 05March23.
ImmunoEpigenetics XXXXI. From Programmed Cell Death to Homeobox gene clusters, T-ALL leukaemias involve epigenetic events. DJGPhD.05March23. Authentic Biochemistry Podcast
ImmunoEpigenetics XXXX. Transcription factor complex permutaions combine with histone acetylomic and methylomic covalent mofications in T -ALL disease. DJGPhD. 04 March 2023. Authentic Biochemistry.
ImmunoEpigenetics XXXIX. T cell acute lymphoblastic leukaemia genetics and epigenetics: the role of chromatin retailoring via histone LYS acetylation/deacetylation event ontology. DJGPhD.3March23
ImmunoEpigenetics XXXVIII. Tcell receptor activation and the PIP3/AKT/mTORCI/mTORCII control over cytokine expression:a primer. DJGPhD.2March2023.Authentic Biochemistry Podcast.
ImmunoEpigenetics XXXVII. Differential substrates for the Adenylate Cyclase-PKA phosphorylation cascade distributes assymetric inflammatory, hormonal and metabolic sequalae. DJGPhD.01March23.
ImmunoEpigeneticsXXXVI. Tumor-specific methylation respondent transcription of Adenylate Cyclase 2 may be linked to differential cytokine expression controlling T cell activation. DJGPhD.01March23.
Immunoepigenetics XXXIV. Methylation signatures in neoplasias1. DJGPhD. Authentic Biochemistry Podcast Productions. 26.2.23
ImmunoEpigenetics XXXIII. Crisper CAS , small molecule,and LOXP-CRE targeting of SDH/ComplexII decrease Th1 cytokine production: Standard Oxidation Potentials and TCA anapleurotic involvement.DJGPhD.
ImmunoEpigeneticsXXXII. Apriori synthesis of the glycolytic/TCA/ETC axis mediating target and endogenous apoptotic control with Th and NK cell activation/proliferation and effector function. DJGPhD.
ImmunoEpigenetics XXXI. The role of SDH on Complex II electron flow to ubiquinone subsequent to cardiac arrest is associated neuronal PCD similar to Tcell bioenergetic switching during activation.
Immunoepigenetics XXX.NK lymphoyctes programed tumor cell death by titrating anti-apoptotic BCL proteins with BH3 pro-apoptotic events. DJGPhD. 17.2.23. Authentic Biochemistry Podcast
ImmunoEpigenetics XXIX. Apoptosis unthwarted:preventing phosphorylation of RNAPOLII tanks histone acetylation near Mcl enhancer region thus epigenetically inhibiting expression in glioblastoma cells.
A Dialectic on Research Scientific Method I. How research questions may be apprehended through the hypothetico-deductive-experimental paradigm. DJGPhD. 14.2.23
ImmunoEpigenetics XXVIII, Synthesis of epigenetically controlled ferroptosis with Cyto-Toxic T Lymphocyte APC/MHC activated IFN-Gamma induced tumor fatty acyl CoA synthase- lipid peroxide mechanism.
Immunoepigenetics XXVII. PKM2 as an epigenetic and metabolic author of cell proliferation leading to tumorigenesis. DJGPhD. 12 Feb 2023. Authentic Biochemistry Podcast
ImmunoEpigenetics XXVI.The repressive deubiquitinase (PR-DUB) inhibits ubiquitinated histone 2A occupancy on SLC7A11 promoter causing cystine starvation and GSH depletion promoting ferroptosis. DJGPhD
ImmunoEpigenetics XXV. Lymphocyte Specific Helicase inhibits ferroptosis while promoting tumorigenesis via fatty acid desaturase gene transcription and subsequent oleic acid formation via CoQ10.DJGPhD
A Biochemical Partita 7th Movement. The articulation of obesity as arbiter of pathophysiology. DJGPhD. 04Feb23. Authentic Biochemistry.
A Biochemical Partita 6th Movement. Human bioenergetics and hormonal regulation involving FA beta-oxidation and gluconeogenesis "discourage" glyoxylate cycle molecular evolution a priori. DJGPhD.
A Biochemical Partita 5th Movement. The hepatic Malate Apartate Shuttle combined with the 2-oxoglutarate carrier facilitate reducing power and the OAA carbon source for cytosolic gluconeogenesis.
A Biochemical Partita 4th Movement.Regulation of gluconeogenesis vs. glycolysis and the fatty acyl CoA beta-oxidation pathway provide REDOX and allosteric control over bioenergetics. DJGPhD.01FEB23.
ImmunoepigeneticsXXIV. The Cathelicidin anitmicrobial peptide cysteine protease domain may contibute to innate immune defense against cancer via epigenetically regulated ferroptosis.DJGPhD.1Feb23
A Biochemical Partita 3rd movement. Principle of Sufficient Reason and the refutation of biological reductionism. DJGPhD.31.1.23. Authentic Biochemistry Podcast Productions
A Biochemical Partita. 2nd movement. DJGPhD. 29.1.23 Authentic Biochemistry Podcast Production
A Biochemical Partita. Ist movement. DJGPhD. 28.1.23 Authentic Biochemistry Podcast Production
ImmunoepigeneticsXXIII. Vitamin D hydroxylation mediated alteration of VDR chromatin retailoring and alteration of promoter methylation generate a dialectically ontological pathophysiology.DJGPhD.
Immunoepigenetics XXII. The role of circulating vitaminD in the regulation of innate immune antimicrobial peptide generation. DJGPhD. 25.1.23 Authentic Biochemistry
ImmunoepigeneticsXXI. Methylation patterns of CpG vs histone modification of specific loci must be sequenced to verify pathophysiological events. DJGPhD. 22.1.23 Authentic Biochemistry.
A Special Message for Authentic Biochemists. A direct way to contact your host and a little more. DJGPhD.21.1.23 Authentic Biochemistry Productions.
Immunoepigenetics XX. Inflammatory cytokines and associated transcription factors are controlled by epigenetically regulated microRNA. DJGPhD.20.1.23. Authentic Biochemistry.
ImmunoEpigeneticsXIX. Diet-induced and db/db mouse model Type 2 diabetes is dissimilar to the human pathophysiology but shares epigenetic mechanisms controlling pro-inflammatory PLA2/COX2/PGE2.
ImmunoepigeneticsXVIII. Variable DNA and histone methylation in cooperation with micro RNA mediate macrophage plasticity,inflammation and wound repair in T2D patients. DJGPhD.18.1.23.AuthenticBiochem.
Epistemological integration into realized metaphysicsV. Energy and mass like space and time are estimations of uncertain certainties yet are used as universals in physico-chemical event ontologies
Immunoepigenetics XVII.TGF beta involvement in disease pathology and normal developmental physiology demonstrates the complexity of categorical ontologies in biochemical events.DJGPhD.13.1.23.AB
ImmunoepigeneticsXVI. TGFbeta 1 and subfamily member Activin A diferentially alter the categorical valence and modality of Th17 cells in multiple sclerosis via receptor kinase modulatory specificity.
ImmunoepigeneticsXV. In utero fetal exposure to high concentration of maternal cortisol can induce histone code hypomethylation proximal to the TGF B-1 receptor resulting in adult OA.DJGPhD.12Jan23
ImmunoepigeneticsXIV. Epithelial cell metabolism and the potential transition to mesenchyma is regulated by TGF-Beta and linked to ALK-1 receptor associated OA. DJGPhD.11Jan23.Authentic Biochemistry.
Biochemical Consequences of Sensorial Phenomenology V. The possibility of Necessary biological modality . DJGPhD. 09Jan23. Authentic Biochemistry.
ImmunoepigeneticsXIII. The interplay of NFKappB and articular cartilage glycosaminoglycan metabolism in regulating pro-inflammatory cytokine expression in OA. DJGPhD.Authentic Biochemistry. 08Jan2023
ImmunoepigeneticsXII. Osteo-Arthritis 1. Clinical manifestation and the role of TGF-Beta. DR. Daniel J. Guerra. 06Jan2023. Authentic Biochemistry Podcast Productions
Cytoepigenetics XI. The Treg essential linneage specific transcription factor FOXp3 promoter is regionally variably demethylated and acetylated to control Th immunosuppression.DJGPhD.04.Jan.23.
Epistemological integration into realized metaphysics III. Mensam de phaenomenus and the concept of evidentiary existentialism in research science. DJGPhD.01Jan23.Authentic Biochemistry.
ImmunoEpigenetics X(A). Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry
Diabetes XXV. Obesity linked disruption of adipose mediated endocrine hormone control over fatty acid turnover from TAG leads to T2D in humans. Dr. Daniel J. Guerra. 3April22.Authentic Biochemistry
Holiday Ethanol Abuse Lecture I. EtoH ingestion, while intoxicating redox metabolism is also a membrane lipid -protein interacting agent that corrupts inwardly rectifying K voltage gated channels.
ImmunoEpigeneticsIX. Promoter/Enhancer proximal and distal epigenetic signatures and transcription factor protein heterogeneity compose gene expression event ontology.DJGPhD.29.12.22.AuthenticBiochem
More "mere" epistemology opening a door to metaphysics II. Non-canonical epi-rational and epi-empirical retailoring of understanding and imagination via research scientific endojectification.DJGPhD.
ImmunoepigeneticsVIII. Protective immunotolerant neonate Th1 inactivity involves IL-12 p35subunit promoter methylation. DJGPhD.23.12.22. Authentic Biochemistry Podcast
Holiday Ethanol Use VIII. EtOH induced cAMP /CREB associated PKA kinase driven phosphorylation cascade co-opts the TLR4-mediated neuroinflammatory/neurotoxic CNS-microglial axis.DJGPhD.22.12.22.AB.
Holiday Ethanol Use VII. EtOH exposure precipitates chromatin methylation associated MCH and chemokine involvement linking arousal, reward and inflammation. DJGPhD.21.12.22 Authentic Biochem.
Mere Epistemology Knocking on Metaphysics for a late December Evening. I. DJGPhD.21 December 2022 Authentic Biochemistry Podcast
Holiday Ethanol Use VI. EtOH associated DNA methylation of neurotransmitter systems opens the door to neurotoxicity and cognitive deficits. DJGPhD.18.12.22b. Authentic Biochemistry Podcast
Holiday Ethanol Use V. EtOH mediated WNT signaling and PLC mediated IP3/DAG induction of protein kinase and Ca2+ mobilization contribute to aberrant transcription and translation corrupting health.
Holiday Ethanol Use IV. MDH and LDH play essential roles in EtOH mediated corruption of bioenergetics, development, and gene expression during fetal development.DJGPhD.16.12.22 b.Authentic Biochem.
Holiday Ethanol Use III. In utero fetal cardiac muscle development is corrupted by maternal EtOH exposure via metabolic, bioenergetic and epigenetic means involving fatty acid and folate redox poise.
Holiday EtOH Lecture II. Ethanol ingestion permanantly corrupts myelin lipid composition while altering MET and Folate metabolism leading to epigenetic syntactic and semantic chromatin errors.DJGPhD.
Immunoepigenetics VII. MicroRNA mediated feedback control over signalling response toward inflammation.DJGPhD. 10Dec22. Authentic Biochemistry
ImmunoepigeneticsV!. TLR's and TCR's use membrane lipid raft signal transduction to obtain transcription factor mediated cell fate via epigenetic modification. DJGPhD.09 Dec.22
ImmunoepigeneticsV. TCR activation and the integration of cell senescence with epigenetic authorship and reading-mediated tumorigenesis. DJGPhD.07Dec22. Authentic Biochemistry
ImmunoEpigeneticsIV. Membrane lipid raft components dynamically mediate Tcell reception, hippocampal pyrimidal neuron endocytosis, and lung cancer cell mesenchymal to endothelial transition.DJGPhD.
Immunoepigenetics 3. EtOH abuse interrupts membrane lipid raft -mediated TCR signaling by decreasing the TF NFAT nuclear translocation and IL-2 transcription.DJGPhD.04.DEC.22.Authentic Biochemistry.
Immunoepigenetics 2. Treg and ILC differentiation and the evolution of lymphocytic response specificity incl. B cell class switch recombination and somatic hypermutation deamination.DJGPhD.2.12.22
Membrane Biochemistry 86/Immunoepigentics1. The complex divergent roles of Inhibitor of DNA (Id) binding proteins in terminal differentiation and disease states. DJGPhD.01.12.22.Authentic Biochemistry
Membrane Biochemistry 85. EBV latent membrane protein induction of haemopoietic proliferative disease and Id repressor protein transcriptionally mediated terminal differentiation.DJGPhD.30.11.22.
Membrane Biochemistry 84. Isolation of membrane protein using non-ionic detergents exposes the prescence of cellular lipid raft domains. DJGPhD. 29.11.22. Authentic Biochemistry.
Membrane Biochemistry 83. Countercurrent distribution theory of membrane lipid raft mediated endomebranous sequence ontology. DJGPhD.26.11.22
Membarne Biochemistry 82. Coda in absentia. Redux of the epistemological lens and the membrane lipid raft resurfaces. Dr. Daniel J. Guerra. 23.11.22. Authentic Biochemistry Podcast
Membrane Biochemistry 81. Synopsis. Logical judgment and square of opposition applied to lipids as transcription factors and membrane sequence derivatives respectively. DJGPhD19.11.22.Authentic Bioch
Membrane Biochemisty.Steroidogenic endo-nuclear sphingolipid metabolism involving ganglioiside turnover mediates transcription factor de-repression via DAG kinase.DJGPhD.18.11.22.
Membrane Biochemistry 79. Sphingolipids and cyclic phosphatidic acid control PPAR isoform-mediated gene transcription over lipid metabolism and inflammation. DJGPhD.16.11.22. Authentic Biochemistry
Membrane Biochemistry 78. Nuclear sphingolipid metabolism controlling cAMP response element-mediated transcription promoting proinflammation and anti-inflammation temporally and spatially.DJGPhD.
Membrane Biochemistry 77. Membrane lipid mediated IGF-I in contextual expression within discrete organ systems controls an inflammatory valence DJGPhD. 9 November 2022 Authentic Biochemistry
Membrane Biochemistry 76. Introduction to SubCellular-Distribution Mechanisms and Function of Nuclear-Localized Lipids. DJGPhD.06Nov22b.Authentic Biochemistry Podcast
Membrane Biochemistry75. Rational judgment as the epistimological prolegomena to research science:isoprenoid lipid biosynthesis guided event ontologies.DJGPhD.6NOV22.Authentic Biochemistry.
Membrane Biochemistry 74. ER-Phosphatidylcholine biosynthesis regulates neuritigenesis and the use of logical judgment in research science. DJGPhD. 03Nov22. Authentic Biochemistry
Membrane Biochemistry 73. Pathogenic membrane associated phosphatidylcholine and sphingomyelin metabolism is linked to skeletal and CNS pathology. DJGPhD.02NOV22. Authentic Biochemistry
Membrane Biochemistry72. DHEA and the steroidogenic pathways as biochemical prolegomena to logical judgments. Dr. Daniel J. Guerra.29.10.22b.Authentic Biochemistry
Membrane Biochemistry 71. Intracellular-endomembranous cholesterol trafficking and estrogen biosynthesis is under epigenetic control. DJGPhD.29.10.22.Authentic Biochemistry.
Membrane Biochemistry 70. Ketogenesis and cholesterologenesis are mediated by mitochondrial bioenergetics and the ER+Peroxisomal metabolism of VLCPUFA's via membrane domain event ontology.DJGPhD
Membrane Biochemistry 69. Distilled electrochemical potential mediated Inner mitochondrial membrane redox and the introduction to sterol involvement.DJGPhD.27.10.22. Authentic Biochemistry
Membrane Biochemistry 68. Elevatum Hypostasis. Dr Daniel J. Guerra. 22.10.22b Authentic Biochemistry
Membrane Biochemistry 67. VDAC oligimerization inhibition can block mitochondria-mediated apoptosis and NLRP3 inflammasome activation. DJGPhD.22.10.22.Authentic Biochemistry.
Membrane Biochemistry 66. Staph aureus infection, autoimmune disease, biliary cholangitis, and neurodegeneration involve NLRP3 Inflammasome activation with core bioenergetic involvement. DJGPhD.
Membrane Biochemistry 65. The integration of pro-inflammatory signaling from a plenum of molecular membranous events: The NRLP3 Inflammsome. DJGPhD. 19.10.22. Authentic Biochemistry.
Membrane Biochemistry 64. Prelude to Biochemical Metaphysics and the Mitochondrial Membrane Damage Response I. Dr. Daniel J. Guerra.18.10.22.Authentic Biochemistry Podcast
Membrane Biochemistry 63. The TCR:APC Chemokine receptor Trigger for Cytokine Stimulation. DJGPhD. 16 Oct 2022 Authentic Biochemistry Podcast
Membrane Biochemistry 62. The T cell receptor mechanism II. Dr. Daniel J. Guerra. 14.10.22 Authentic Biochemistry
Membrane Biochemistry 61. The Tcell membrane :APC synapse I. Dr Daniel J. Guerra 13.10.22 Authentic Biochemistry
Membrane Biochemistry 60. Human neocortical membrane lipid evolution and the links to cognition,fasting, and neurodegeneration. Dr Daniel J. Guerra. 03Oct2022.Authentic Biochemistry.
Membrane Biochemistry 59. Back to the Basics.Dr Daniel J. Guerra 30 September 2022.Authentic Biochemistry
Membrane Biochemistry 58. Cardiolipin biosynthesis involves a PC-linoleic acid requiring maturase and a unique phosphatidylglycerol phosphate phosphatase. DJGPhD.25.9.22.Authentic Biochemistry
Membrane Biochemistry 57. c-Fos osteoclastogenesis and control over acetyl ceramide mediated apoptosis.Dr Daniel J.Guerra.22.9.22 Authentic Biochemistry
Membrane Biochemistry 56. Membrane Associated Cholesterol hydroxylation leads to bile acid conjugate- promoting human breast cancer stem cell proliferation. DJGPhD.19.9.22 Authentic Biochemistry.
Membrane Biochemistry 55. A phosphoglycerolipid primer. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 16 Sept. 2022.
Membrane Biochemistry 54. De-phospho TYR cFos doubles the VMax of specific glycolipid and phospholipid biosynthetic enzymes via ER stabilization.Dr Daniel J. Guerra. Authentic Biochemistry.14.9.22
Membrane Biochemistry 53. cFos correlates with light-induced retinal membrane retailoring without de novo transcription. Dr Dan Guerra. 13.9.22.Authentic Biochemistry Podcast
Membrane Biochemistry 52. Epigenetic modifications in pathophysiology and the synthesis of nascent membrane lipid in cell cycle progression. DJGPhD.12Sept22. AUthentic Biochemistry
Membrane Biochemistry 51. The BRD4 epigenetic reader control over cardiac mitochondrial function via bioenergetic gene expression may be corrupted in oncogenic pharmacotherapy driven BETi. DJGPhD.
Membrane Biochemistry L (50). SCFA's work via membrane free fatty acid receptors through transcription factor Nrf2 to reduce ROS with an epigenetic mark-up.DJGPhD.7Sept22.Authentic Biochemistry.
Membrane Biochemistry 49. linking membrane reception and endocrine steroid lipid signaling to disease and longevity.DJGPhD.06Sept22
Membrane Biochemistry 48.Coxsackievirus B enterovirus causes myocarditis in young men due to lack of estrogen-receptor-mediated control of mitochondrial fission/fusion & inflammation. DJGPhD.3Sept22
Membrane Biochemistry 47. AMPK is regulated by steroid hormone activating kinases and calcium. DJGPhD. 02September2022, Authentic Biochemistry Podcast
Membrane Biochemistry 46. Lung and endometrial cancer vs neurodegersative disease in steroid-sex-hormone NK cell biochemistry.DJGPhD.31.8.22. Authentic Biochemistry.
Membrane Biochemistry XXXXV. Female NK Cytotoxicity due to Membrane Surface Receptors may Obtain Reduced Pathogen Infection Rates and Cancer in Women v. Men.DJGPhD.30.8.22 Authentic Biochemistry.
Membrane Biochemistry 44. Synthesis of Lectures Video. Part One. Attached in show notes. Dr. Daniel J. Guerra. 29.8.22 Authentic biochemistry Podcast.
Membrane Biochemistry 43. Action potentials and the mechanisms of electrochemical communication in biological systems. DJGPhD.26.8.22. Authentic Biochemistry
Membrane Biochemistry XXXXII. Basic Electrobiochemistry of Biological Membranes. Dr Daniel J. Guerra. 24.8.22b Authentic Biochemistry Podcast Audio Lectures.
membrane Biochemistry XXXXI. A priori Synthesis of Sex-linked Biochemical Dimorphism and Canonical Membrane Event Ontology. Dr. Daniel J. Guerra. 24.8.22.Authentic Biochemistry Podcast.
Membrane Biochemistry XXXX. Immunological Response to Molecular Sex-linked Pattern Dimorphism Includes the Presentation of Differential Autoinflammatory Diseases. DJGPhD 22.8.22b.Authentic Biochem.
Membrane Biochemistry XXXIX. Maternal Inheritance of Mitochondrial DNA and the Heterozygous XY Chromosomal Contributions to Sexually Dimorphic Biochemical Processes.DJGPhD.22.8.22. Authentic Biochem.
Membrane Biochemistry XXXVIII. Sexual Biochemical Dimorphism Epigenetic Involvement in Early Infant CRF/HPA Axis and Subsequent Adult Neuropsychiatric Disease. DJGPhD.19.8.22. Authentic Biochemistry.
Membrane Biochemistry XXXVII. CRF Receptor Studies in Pre-Clinical Research as Bootstrapped to Human MDD, GAD, PTSD and Addiction.DJGPhD.19.8.22. Authentic Biochemistry
Membrane Biochemistry XXXVI. Sexual Differential CRF Signaling Accorded to Downstream Processing and Associated Neuropsychiatric and Phyiological Disorders.DJGPhD.17.8.22 Authentic Biochemistry.
Membrane Biochemistry XXXV. Lipocortin-1 induces cortisol thus suppressing phospholipase A2, blocking eicosanoid and leukocyte inflammatory events. DJGPhD.16.8.22. Authentic Biochemistry
Membrane Biochemistry XXXIV. Assymetric Glucocorticoid Pharmacotherapy in Rheumatoid Autoimmune Disease with T2Diabetes and the Fear Axis.DJGPhD.Authentic Biochemistry 15.8.22
Membrane Biochemistry XXXIII> Are Oxytocin and Corticotropin Releasing Factor Antiinflammatory, Analgesic and Anxiolytic? Dr Daniel J. Guerra. 14.8.22. Authentic Biochemistry
Membrane Biochemistry XXXII. The Subcortico-limbic network in Fear Conditioning as seen through the Dialectical Event Ontology lens. DJGPhD.10.AUG.22. Authentic Biochemistry
Membrane Biochemistry XXXI. Corticotropin Releasing Factor and "Fear" Neurobiochemical Correlates in the CNS. Dr Daniel J. Guerra. 9Aug2022. Authentic Biochemistry Podcast
Membrane Biochemistry XXX. Nociception as component of Subcortical-Limbic Involvement of the Conditioned Fear Response in Mammals. DJGPhD. 8Aug22. Authentic Biochemistry
Membrane Biochemistry XXIX. Final discussions on serum albumin and membrane disruption mediated inflammatory modulation. Dr. Daniel J. Guerra. 7bAug22.Authentic Biochemistry.
Membrane Biochemistry XXVIII. Serum Albumin as an arbiter of neuronal inflammation or peripheral removal of circulating endogenous Danger/Damage-Associated Molecular Patterns. 7Aug22. DJGPhD.
Membrane Biochemistry XXVII. Traumatic Brain Injury and Ischaemic Stroke associated neuroinflammation is mediated through membrane caveolae. Dr Daniel J. Guerra.3Aug22. Authentic Biochemistry.
Membrane Biochemistry XXVI. Lipid molecular structures and membrane morphology impacting biological activity. Dr Daniel J. Guerra. 01August2022. Authentic Biochemistry Podcast Productions.
Membrane Biochemistry XXV. From Plotinus through Kant to Membrane lipids: an a priori synthesis of research scientific event concepts. DJGPhD.Authentic Biochemistry.31.7.22
Membrane Biochemistry XXIV. Legionella- assocated TLR mediated LPS containing sialic acid interactions and the Caveolar Involvement in Pathobiochemistry.DJGPhD. 29.7.22.Authentic Biochemistry.
Membrane Biochemistry XXIII. DNA recombination and methylation associated autoimmune and cancer pathology via TLR4 and membrane lipid rafts. DJGPhD.28.7.22. Authentic Biochemistry
Membrane Biochemistry XXII*. The dialectical event ontology of caveolae-associated disease is florid with no absolute relational, quantitative, qualitative or modal conformity.DJGPhD.27.7.22
Membrane Biochemistry XX. Loss of CNS CA1-Caveolae Formation in Obese Type-2 Diabetics is Linked to insulin Resistance and Alzheimer's Disease. DJGPhD24.7.22. Authentic Biochemistry.
Membrane Biochemistry XIX. Oxysterols and LDLR in atherosclerosis: transcriptional mediation of membrane control over cholesterol homeostasis. 21.7.22. DJGPhD.Authentic Biochemistry
Membrane Biochemistry XVIII> Valproic acid and Platelt Activating Factor:Membrane lipids in Alzheimer's DiseaseDJGPhD 18.7.22 Authentic Biochemistry
Membrane Biochemistry XVII. Epoigenetic changes in protein controlled membrane lipid transport in human disease. DJGPhD.14.7.22
Membrane Biochemistry XVI. The Acid Sphingomyelinase Deficiencies. Dr Dan Guerra. 13.7.22 Authentic Biochemistry
Membrane Biochemistry XV. REST mediated gene repression and membrane function and plaque formation in atherosclerosis. DJGPhD. 11JUly22. Authentic Biochemistry
Membrane Biochemistry XIV. Apoptosis and Necroptosis review. Dr. Daniel J. Guerra. 8 July 2022. Authentic Biochemistry Podcast
Membrane Biochemistry XIII.Fatty acid induced membrane protein phosphorylation can shift pro-oncogenic to apoptotic cell fate in human breast cancer cell lines. DJGPhD. 5July 2022 Authentic Biochem.
Membrane Biochemistry XII. The specificity of membrane lipid raft molecular species and the dialectics of protein sorting. DJGPhD.3 July 2022 Authentic Biochemistry.
Membrane Biochemistry XI. Inflammasomes and omega three fatty acid involvement in various pathogenic and human disease states. DJGPhD.02.July 2022.
Membrane Biochemistry X. Dialectical Event Ontologies and the Complexity of Biological Systems. Dr. Daniel; J.Guerra 2 July 2022 Authentic Biochemistry
Membrane Biochemistry IX. Omega Three fatty acid utilization via oxygenation to control inflammation. DJGPhD. 30.6.22 Authentic Biochemistry Podcast production
Membrane Biochemistry VIII. The basics of lipid membranes. Part 1. Dr Daniel J. Guerra. Authentic Biochemistry Podacst Production. 28.6.22
Membrane Biochemistry VII. DNA methylation and histone acetylation may be at the core of memory and learning via LTP associated Integral Membrane Excitation. DJGPhD.24.6.22 Authentic Biochemistry.
Membrane Biochemistry VI. The involvement of membrane lipid omega 3 fatty acids in LTP and memory acquisition. Part 1. Dr Guerra. 23.6.22. Authentic Biochemistry
Membrane Biochemistry V. Epigenetic alteration of gene expression is predicated by free will induced synaptic plasticity as an event ontology. DJGPhD. 21.6.22 Authentic Biochemistry
Membrane Biochemistry IV. Synaptic Plasticity and Oncological Phenomena involving DNA Methylation. Dr. Daniel J. Guerra. 20.6.22 Authentic Biochemistry
CytoEpigenetics XIX. Some examples of epigenetic methylation and acetylation patterns in disease and the concept of maintenance methylation. Dr Daniel J. Guerra. 06June2022
CytoEpigenetics XVIII. Membrane lipid architectonics organized for cell cycle and both nuclear and mitochondrial biochemical mediation of gene expression. Dr. Dan Guerra. 05 June 2022
CytoEpigenetics XVII. The role of ceramide metabolism in epigenetic and bioenergetic cross talk among multiple subcellular compartments. Dr Dan Guerra. 03June2022 Authentic Biochemistry Podcast
CytoEpigenetics XVI. The Mt DNA replicase and helicase enzymes are epigenetically nuclear encoded and localize to the mitochondrial membrane into lipid rafts containing cholesterol. DJGPhD. 2June2022
CytoEpigenetics XV.An AMPK phosphorylation cascade promoting mTOR pro-translational induction of NFkappa-B SASP transcription is modulated by NAD+ Sirtuin and PARP during Chromatin retailoring.DJGPhD
CytoEpigenetics XIV. The details of AMPK mediated control over DNA methyl transferase thus coordinating bioenergetics with cell fate via the epitranscriptome. DJGPhD. 25.5.22
CytoEpigeneticsXIII. Epitranscriptomics of Fatty acid Utilization is a driver of Heart-Failure associated Cardiorenal disease. Dr daniel J. Guerra. Authentic Biochemistry.22.5.22
CytoEpigenetics XII. The central role of mitochondria in regulating cell fate and metabolic switching is necessary and universal in epigenetic modification of gene expression. DJGPhD.20.5.22
CytoEpigenetics XI. The interactive intermediary metabolic architectonic of methylation and acetylation in epigenetic mediation of gene expression between the mitochondria and nucleus. DJGPhD.17.5.22
CytoEpigenetics X. The IDH isofrom roles of mutant, hypoxic and constitutive activities mediate DNA, RNA and Histone3 Lys methylation patterns thus redirecting gene expression.DJGPhD.15.5.22
Cytoepigenetics IX. c-MYC controls transcription of two dehydrogenases that alter the ratio of 2-HG/alphaKG thus controling epigenetic signatures on DNA and RNA in a cancer mouse model.DJGPhD.11May22
CytoEpigenetics VIII. The epigenetic processors, TET and BRD4, mediate control over fatty acid oxidation, pyruvate metabolism, the electron tranport chain and OXPHOS. DJGPhD.8May22. Authentic Biochem
Cytoepigenetics VIIB. Warburg glycolysis explained from an epigenetic perspective plus some details of DNA methylation/demethylation. DJGPhD. Authentic Biochemistry Podcast 06May2022
Cytoepigenetics VIIa. Micro RNA control over the electron transport chain and oxidative phosphorylation via binding to nuclear and mitochondrial transcripts. DJGPhD03.may 2022. Authentic Biochemistry
CytoEpigenetics V!. The 'magmatic' alteration of nuclear and mitochondrial gene expression via microRNA processing and translocalization is under bioenergetic control. DJGPhD. 2 May 2022.
Cytoepigenetics V. Small interfering and micro RNA mediate mitochondrial and nuclear transcripts thus rendering cell fate, bioenergetics, and immunogenicity. DJGPhD.29.4.22. Authentic Biochemsitry
Cytoepigenetics IV. Using Raman and IR spectroscopy to analyze the physical chemistry of pyrimidine nucleotide methylation. Dr. Daniel J. Guerra. 26.4.22. Authentic Biochemistry Podcast Productions
Cytoepigenetics IIIB. The Geometrical constraints decribed by the valence shell electron pair repulsion in biochemical reactivity. DJGPhD.25.4.22
Cytoepigenetics IIIA. Dissection of the PPAR-gamma epigenetic retailoring. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 25.4.2022
Cytoepigenetics II. The First Principle of Biochemical Epigenetics and the dialectic of methylated promoter region PPAR-gamma and peroxisomal mitigation between rodent and human. DJGPhD.24.4.22
CytoEpigenetics I. Introduction. Dr. Daniel J. Guerra . 22.4.22. Authentic Biochemistry Podcast Productions
Authentic Biochemistry is moving to a remote geographical region but will do so seamlessly and with full dedication. Please SUBSCRIBE and take notice of the discussion I have recorded here. DJGPhD
Diabetes XXXVI. Coda. Final lecture in diabetic dyslipidaemia.
Diabetes XXXV. Rodent model adipose mitochondrial respiratory contribution to obesity control involves a selenium protein and UCP1 sulfenylation. Dr Daniel J. Guerra. Authentic Biochemistry.18.4.22
Diabetes XXXIV. White vs brown adipocytes and the role of transcription factors and metabolic enzyme expression to mediate bioenergetics vs.lipogenesis in store depot fat.DJGPhD.17.4.22. Authentic B.
Diabetes XXXIII. Synthesis of lecture arc Part 2. Dr Daniel J. Guerra. Authentic Biochemistry Podcast Studios. 16.4.22
Diabetes XXXII. Fatty acid oxygenation and use of eicosanoid molecular species to regulate T2D-linked inflammation via the agonization of the nuclear receptor transcription factor PPAR.DJGPhD 15.4.22
Diabetes XXXI. REDOX biochemistry mini-review and the roles of essential fatty acid elongation/desaturation metabolism and COX/LOX oxygenation as ligands for PPAR isoforms in T2D pharmacotherapy.
Diabetes XXX. The pleitropic roles of free fatty acids and PPAR's as mediating insulin sensitivity, intermediary metabolism and the inflammatory response in T2D.Dr Daniel J. Guerra 13.4.22. Authentic
DiabetesXXIX. THe CNS axis of Obesity-linked T2D via alterations in PPAR transcription factor mediated expression of ameliorative hippocampal AMPAR and LTP neural transmission in Alzheimer's Discsease
Diabetes XXVIII. Diabetic nephropathy is a consequence of non-esterified free fatty acid associated ceramide induction of the IRS-1 phosphorylation in glomerular podocytes inducing inflammation
Diabetes XXVII. Dyslipidaemia and the Insulin Resistance Axis. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast 7April2022.
Diabetes XXVI. Adipogenic and hypertrophic adiposity differentially control dyslipidaemia and Insulin resistance in association with pro-inflammatory cytokine induced T2D and breast cancer.DJGPhD.
Diabetes XXIV. Sphingosine 1-phosphate targeting and the abalation of primary breast cancer metastasis: IL6 mediated tumorigenesis blockade? Dr Daniel J. Guerra 01April2022. Authentic Bbiochemistry
Diabetes XXIII. Obesity-associated IL6 and sphingosine 1-phosphate are linked to breast cancer.Dr. Daniel J. Guerra. 31 March 2022. Authentic Biochemstry
Diabetes XXII. Obesity and cancer are linked by inflammation and dyslipidaemia. Dr Daniel J. Guerra. 30.3.22 Authentic Biochemistry
Diabetes XXI. TAG accumulation in skeletal muscle of diabetics vs athletes and suggested role of Intramuscular TAG in Insulin Resistance due to subcelluar localization of lipid droplets. DJGPhD.27.3
Diabetes XX. Intermediary metabolic allosteric regulation in the Myocardial Infarcted heart reveals HF aetiology from obesity-linked Type 2 Diabetes. DJGPhD.25.3.22. Authentic Biochemistry Production
Diabetes XIX. THe ketogenesis bioenergetic system can be corrupted via DAG-kinase mediated pyroptosis in the obese/T2D CNS. Dr. Dan Guerra. 22.3.22. Authentic Biochemistry Podcast
Diabetes XVIII. Myokine mediated muscle mass signaling is corrupted by obesity linked Type 2 diabetes via massive inflammation and dyslipidaemia.DJGPhD. 21.3.22. Authentic Biochemistry
Diabetes XVII. Short and medium chain fatty acid derived ketones and skeletal muscle Myokines to improve cognitive and homeostatic well-being in humans. DJGPhD. 20.3.22 Authentic Biochemistry.
Diabetes XVI. Fornix white matter fascicular region of the hippocampus nuclei is spared from neurodegeneration by dietary medium chain saturated fatty acid. DJGPhD.Authentic Biochemistry19.3.22
Diabetes XIV. The Neuropsychiatric/Neurodegeneration axis from Sphingomyelin Degeneration to Increased Inflammation. Dr. Daniel J. Guerra. 17.3.22. Authentic Biochemistry Productions
Diabetes XII. Free fatty acid dyslipidaemia associated dysregulation of hepatic and skeletal muscle Insulin Receptor Substrate (IRS)1/2 axis. Dr. Daniel J. Guerra15.3.22. Authentic Biochemistry .
Diabetes XI. Biometrics in research interpretation. Dr Dan Guerra 14.3.22 Authentic Biochemistry.
Diabetes IX. The role of peroxisomes in ether-linked lipid biosynthesis. Dr.Daniel J. Guerra. 07March2022. Authentic Biochemistry Podcast production
DiabetesVIII. Subcellular organization and the role of lipid metabolism in mitochondria and peroxisomes. Dr Daniel J. Guerra. 05March22. Authentic Biochemistry
Diabetes VII. Cholangiocarcinomas and the corruption of the biliary system as sequalae of obesity and associated pancreatic exocrine insufficiency of diabetes. Dr Dan Guerra. 3.March.2022. A.B.
Diabetes V . PEI and Diabetic Dyslipidaemia with Primary Cholagiocarcinoma. Primer on lipid digestion and Lipoprotein Trafficking. Dr. Dan Guerra. Authentic Biochemistry 01.March.2022
Diabetes IV. Pancreatic Exocrine Insufficiency in Types I, II, and III Diabetes Mellitus. Dr DAniel J. Guerra. 28.2.22. Authentic Biochemistry
Diabetes III. Sphingosine 1-Phosphate in glioblastoma and prostagladin E2/EP4 in diabetic nephropathy-an axis of angiogenesis. Dr. Daniel J. Guerra. 25.2.22 Authentic Biochemistry
Diabetes II. The Insulin resistance factor and glucose intoxication associated dyslipidaemia and introduction to diabetic nephropathy. DJGPhD. 23.2.22. Authentic Biochemistry Podcast.
Type 2 Diabetes I. Initial lecture describing insulin resistance and dyslipidaemia. Dr Daniel J. Guerra 22.2.22 Authentic Biochemistry Podcast.
Fatty Acids IX. The Monounsaturated fatty acid inhibition of ferroptosis and apoptosis leads to cancer progression. Pharmacotherapeutic Considerations. Dr Daniel J. Guerra. 17.2.22 Authentic Biochem.
Fatty Acids VIII. The Potential for Ferroptosis enhancement via inhibition of Stearoyl CoA Desaturase as pharmacotherapy in Pancreatic Ductal Carcinoma.DJGPhD.16.2.22. Authentic Biochemistry.
Fatty Acids VII. Stearoyl CoA Desaturase biochemistry and assocation with immune and metabolic disease. Dr Dan Guerra
Fatty Acids VI. The Inflammasome paradigm and transcription factor-mediated cytokine production as result of high carbohydrate diet and obesity. Dr. Daniel J. Guerra. 10.Feb 2022. Authentic Bichem.
Fatty Acids V. Ketogenesis as a therapeutic to redistribute preserved Heart Failure cardiac ejection fraction via blockage of mitochondrial protein hyperactylation. DJGPhD.9FEB22. Authentic Biochem.
Fatty Acids IV. Adipocyte lipases and the Diacylglycerol PKC/PKD circuit of cellular degeneration leading to chronic inflammation-associated obesity. DJGPhD.07.Feb.22. Authentic Biochemistry
Fatty Acids III. The inflammatory diseases and the correlation to dyslipidaemia. Dr Dan Guerra. 05 February 2022. Authentic Biochemistry Studios.
Fatty Acids II. Obesity and lipotoxicity. Dr Daniel J. Guerra. Authentic Biochemistry 04. February 2022
Fatty Acids I. Dr. Daniel J. Guerra. 03.02.22. Authentic Biochemistry Podcast
Anabolism VII. The allosteric control of purine biosynthesis involves complementarity and recipricol maintenance of steady state ADP/GDP ratios. DJGPhD. 31.01.22. Authentic Biochemistry.
Anabolism VI. de novo Purine Nucleotide Biosynthesis. Dr. Dan Guerra. 30.01.22. Authentic Biochemistry
Anabolism V. The nucleic acids. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast.28.01.22
Anabolism IV. Cholesterologenesis. Dr Daniel J. Guerra. 26 January 2022. Authentic Biochemistry Podcast
Anabolism III. Fatty acid synthesis de novo . Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Productions. 25.01.22
Anabolism II. The role of Acetyl CoA Carboxylase isoform expression and discrete allosteric regulation in controlling hepatic fatty acid metabolism. Dr Dan Guerra. 23.01.22. Authentic Biochemistry.
Anabolism I. Dr Daniel J. Guerra Authentic Biochemistry Podcast Production 22.01.22
Membrane lipid provide the architectonic signatures for cellular interactions including avirulence and either systemic and systematic-inflammatory disease. DJGPhD. 17.1.22. AuthenticBiochemistry
Porphyria gingivalis derived dihydroceramides and serine dipeptide lipids secretion induce periodontitis and systemic hyperinflammation as associated with obesity and high sucrose diet. DJGPhD.16.1.22
Dihydroceramides as virulence factors in periodontal disease. Dr. Daniel J. Guerra Authentic Biochemistry. 15 January 2022
Pathogenesis and Virulence are Linked to Alterations in the Infection Court via Secretion of Bacteriocins in Dental Plaque-producing Caries and S. pneumoniae Migration to the Lower Respiratory Tract.
Acquired Molecular Evolution of Antibacterial Resistance Unintentionally Selected via Pharmacotherapy to Counteract Natural Avirulence. DJGPhD. Authentic Biochemistry. 12.Jan2022
Avirulence protein factor heterogeneity in multiple mammalian host/pathogen interactions. Dr. Dan Guerra. Authentic Biochemistry Production.11.Jan.2022
Avirulence in the Streptococci and the Two-Component System of Histidine Kinase and Response Regulator. II. DJGPhD. Authentic Biochemistry 09Jan2022
Avirulence and the mechanisms of pathobiochemistry I. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production. 08.Jan 2022
The neuronal porosomal and synaptosomal structural anatomy as a product of membrane lipid vesicular trafficking, Dr. Daniel J. Guerra Authentic Biochemistry. 05 January 2022
The bioenergetic glucose sensing network of the appetitive reward pathway is linked to the periphery via the neuroendocrine system. DJGPhD. Authentic Biochemistry. 04.Jan.2022
The Motor Neuron Association to Reward Pathway: Motor Neuron Disease , an Introduction. Dr. Daniel J. Guerra. 03 January 2022. Authentic Biochemistry Productions.
The CNS and Pandemic Obesity: The Appetitive Reward Pathway, Energy Expenditure, and Neuroendocrine Signaling. DJGPhD. 02.Jan.2022 Authentic Biochemistry Productions.
A short Pharmacology lecture on New Year's Day 2022. Dr Daniel J. Guerra. Authentic Biochemistry
Appetitive Reward Pathway III.-Neurobiochemistry and Epigenetics of Addiction. DJGPhD. 31.12.21 Authentic Biochemistry
Anhedonic and MDD- Associated Appetitive Reward Pathway Biochemistry and Pathophysiology II. DJGPhD. Authentic Biochemistry.30..12.21.
Appetitive Reward Pathway Biochemistry and Neural Circuitry Regulation I. Dr. Daniel J. Guerra. 29.12.21. An Authentic Biochemistry Production.
AMPK and Immuno-Epigenetic Biochemistry Part 2/2/ DJGPhD. Authentic Biochemistry 27.12.21
AMPK and Immuno-Epigenetic Biochemistry Part 1. Dr. Daniel J. Guerra. 27.12.21. Authentic Biochemistry
AMPK negatively regulates lipogenesis by phosphorylating ACCase 1&2 plus HMGCoA reductase thus supporting beta oxidation of fatty acids . Dr. Daniel J. Guerra. 22.12.21. Authentic Biochemistry
AMPK is associated with the POMC vs, NPY neuronal axis under Leptin Control. DJGPhD. 20.12.21 Authentic Biochemistry
AMPK Allosteric Regulation and Interaction with the Opposing mTORC Network. Part 2. Dr. Daniel J. Guerra. Authentic Biochemistry 19.12.21
Bio-Molecular Regulator Series . AMPK. Part One. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production.19.12.21.
T-lymphocyte and macrophage membrane CD38 ecto-enzyme mediated NAD catabolism is associated with ageing and the decline in Sirtuin-mediated deacylase activity. DJGPhD.11.Dec.21' Authentic Biochemistry
Aposteriori synthesis of neuroendocrine linked clock chronicity and the Senescent associated Secretory Phenotype through the synthetic apriori lens of NAD+. DJGPhD.10Dec21. Authentic Biochemistry
How testosterone-aromatase derived estradiol transformation to 2-methoxy-17beta-estradiol can mitigate cell proliferation by promoting a senescent phenotype.DJGPhD. Authentic Biochemistry.8.DEC.21
Blocking cellular senescence may suppress autoimmune diseases and reactive oxygen mediated cell death but non-ironically promote oncogenesis and tumor development during ageing. DJGPhD. 06.DEC.21
Ageing and Asymmetric Dimethylarginine (ADMA)in Endothelial Nitric Oxide Synthase inhibition-associated decrease in respiratory vasodilation. Dr Dan Guerra 24.11.21 Authentic Biochemistry
Closing the window and drawing the curtain: cancer phenotypes are resolute signatures of Immunosenescence and inflammaging induced epigenetic collapse of vital biochemical homeostasis. DJGPhD.20/11/21
Sealing Fate: Immunosenescent and inflammatory mechanisms combine the ineffectual with the increscent pathophysiology of sickness unto death. DJGPhD. 17.11.21
The interplay between Immunosenescence and inflammaging conduct the innate and acquired immune response toward functional cellular rigidity and incompetence obtaining morbidity and mortality. DJGPhD.
Fine detail of Treg cell control over inflammation suppression via FoxP3 transcriptional modulation. Aging and Obesity will limit this control leading to hyperinflammation. DJGPhD. 08Nov2021
T cell receptor signaling kinase dynamics after APC activation. Co-activating CD28 becomes deficient via immunosenescence thus corrupting T cell efficiency in the elderly. 26.10.2021 DJGPhD.
Indeed oxysterol LDL , circulating hepatic-derived convertase, T lymphocyte differentiation and macrophage to foam cell degeneration obtain the aging cardiovascular/pulmonary pathophysiological state.
How Oxysterol LDL associates with macrophage and T lymphocyte infiltration during aging to generate the hyperinflammatory atherosclerotic plaque. DJGPhD. 19.10.21. Authentic Biochemistry.
Aging results in corruption of T lymphocyte differentiation associated with chromatin instability and epithelial to mesenchymal transitions leading to the pre-cancerous state. DJGPhD 16.10.21
Lymphocyte maturation and the special Innate like Lymphocyte Subclass including Natural Killer and other ILC lineages. DJGPhD.14.10.21. Authentic Biochemistry
Immunosenescence and Inflammaging via thymic Involution and comorbid pathophysiology of obesity and aging present a chronic inflammatory phenotype prone to morbidity. DJGPhD. Oct.04,2021. Authentic BC
Natural cytotoxicity receptors (NCR's) within group 3 innate lymphoid cells (ILC3): an association of transcription factors in IBD's and aging. DJGPhD. 03.10.21 Authentic Biochemistry.
Omega three fatty acids and PE N-methyl transferase are associated with methylation and acetylation patterning in NK cells via AMPK and stress.DJGPhD. 29 September 2021.
Natural Killer Cell switching via demethylation of Histone 3 LYS may correlate with the human aging phenotypic hyper-inflammatory state. DJGPhD. 28.9.21
The Genome and the Immunoepigenome interact across a three-way trigonal planar field with the Environment to Obtain the Aging Phenomena. DJGPhD.27.9.21
Natural Killer cells and the epigenomics of gene expression: implications for the aging -senescent human. DJGPhD. 26 .9.21. Authentic Biochemistry
REDOX Biochemistry Primer . DJGPhD Authentic Biochemistry . 24.9.21
Video Lecture Announcement. Please Listen to this audio! Grazie, Dr. Daniel J. Guerra 22.9.21
The Interferon I role in autoimmune disease and the corruption of mechanisms that lead to age-related morbidity and mortality.DJGPhD. 22.9.21
The Aging Immune Response and Cellular Differentiation are characterized by Apoptosis vs. Necroptosis Mechanisms. DJGPhD. 20.9.21.Authentic Biochemistry Productions.
Semaphorin works through mToR and thus the abl and AKT kinases in Macrophage reverse switching from lipogenesis to fatty acid oxidation. DJGPhD 18.9.21.
Macrophage and T lymphocyte Inclusion to the Aging Human Pathobiochemical Phenotype. DJGPhD.Authentic Biochemistry 18.9.21
Invitation to Watch my Youtube lecture I on the Aging Human Dialectic. Link found in the show notes. DJGPhD 16.9.21
Membrane Biochemistry Primer and Introduction to Aging. Dr. Daniel J. Guerra. Authentic Biochemistry Productions. 13.9.21
Summer Fades and Aging Advances through non-coding RNA's and the Immunological Axes. Dr Daniel J. Guerra. 9.9.2021 Authentic Biochemistry Productions.
Hepatic Gluconeogenesis and Glycogen Metabolism: Canonical Allostery. Dr Dan Guerra. Authentic Biochemistry 07 Sept. 2021
The hormonal and allosteric control over hepatic PFK2/FBPase2 via adenylate cyclase and Fructose 2,6 bis phosphate. DJGPhD.5Sept.2021. Authentic Biochemistry Productions.
Glycerol 3-phosphate dehydrogenase mechanism and the finale of glycolysis. Authentic Biochemistry. Dr. Daniel J. Guerra 27.8.21
Haemoglobin: Molecular Oxygen Binding Cooperativity and the role of 2,3 bis phosphoglyceric acid. DJGPhD 19.8.21
A Necessary Interruption in Amino Acid Catabolism: Haemoglobin and Oxygen Transport Lecture I. DJGPhD. 11 August 2021
Amino Acid Catabolism (Continued): Neurotransmitter and S-adenosyl MET interconversions. DJGPhD 09 Aug 2021
Main Frame Amino Acid Degradation Pathways and Skeletal Muscle Performance and Ammonia Toxicity.02.Aug.2021. DJGPhD. Authentic Biochemistry
The Urea Cycle and the endothelial ARGININE-Nitric Oxide Connection. DJGPhD 27.7.21.Authentic Biochemistry Podcast
The Glutamate Dehydrogenase Axis Further Reveals the Role of Ischaemic Oxygen Availability for Neural Transmission in the Aging Brain. DJGPhD 20.7.21.
The Glutamate Axis of Bioenergetics, Neurotransmission and Potential Contribution to the Aging Senescent Phenotype. DJGPhD 20.7.21
Amino acid metabolism I: An initial primer for subsequent discussions in Aging. Dr Guerra. 07July2021. Authentic Biochemistry.
Mesenchymal stem cell fate and the mediation of age-associated senescence or plasticity in the elderly via immune response valency. DJGPhD 03 July 2021
Detailing the Senescent to Mesenchymal Transition in Aging : Links to Cancer vs. Apoptosis. DJGPhD 28 June 2021.
Genomic damage, DDR, and the roles of inflammation and DNA epigenetic retailoring in the senescent phenotype. DJGPhD 24.6.21
Pharmacodynamics: General Considerations and Clinical Trials. Dr. Dan Guerra. Authentic Biochemistry 12 June 2021
Pharmacokinetics Synoptic with an Introduction to Aging Phenomena. Dr Daniel J. Guerra. 09June2021 authentic Biochemistry.
Cardiovascular disease risk and malnutrition are associated with aging morbidity and obesity. Dr. Guerra. 8 June 2021. Authentic Biochemistry
Ceramide mediated pathophysiology of aging-associated neurodegeneration. Dr. Dan Guerra. Authentic Biochemistry.05 June 2021.
Immuno Endocrine Regulation of Metabolism May-June 2021. Dr. Dan Guerra Authentic Biochemistry.
Aging and Cancer Via Immunosenescence and Pro-inflammatory Cytokines: Relative loss of Naive T cell Populations in the Elderly. DJGPhD. 26 March 2021
Pathobiochemical linkages between Alzheimer's Disease and Autism Spectrum Disorders: Associative Molecular Patterns with Diverse Pathologies. DJGPhD. 18 May 2021
Immunomodulatory effects on neuropsychiatric states: classic rodent model studies. Dr. Guerra. 17.5.21 Authentic Biochemistry
Linking TLR's with the VTA and NE circuitry: Immune mediated neurodegeneration and neuroprotection in the balance. DJGPhD 16 May 2021
Microglial TLR activation mediates Aging-Associated CNS Neurodegeneration. Dr. Daniel Guerra. Authentic Biochemistry Podcast. 13 May 2021.
The Innate Immune Response Instantiates the Pattern for future Inflammatory Prodromal Neurodegeneration. DJGPhD. 08May 2021
Pattern Recognition Receptors: Some molecular detail. DJGPhD Authentic Biochemistry. 07 May 2021
Ischemic Infarct as a model for immune mediated CNS regeneration or degeneration via microglial stimulation. Dr. Daniel J Guerra. Authentic Biochemistry . 06May2021
Lymphocyte and Resident Microglia participate in CNS formation, Epigenetic Modifications and Neurodegeneration via RAG-Recombinase. Authentic Biochemistry Podcast by DJGPhD. 27 April 2021
The RAG Recombinase Interacts with T lymphocyte Programmed Cell Death Loci. Dr Dan Guerra Authentic Biochemistry Podcast 26 April 2021
Dr. Guerra presents: The CNS and the Immune System are linked to Recombination and the Epigenome. Lecture IV. 24.4.21 Authentic Biochemistry
Authentic Biochemistry Neuroimmune and Epigenetic Interactions in Aging III. DJGPhD 21.4.21
The immune system is both genetically programmed and environmentally adaptable to epigenetic states. Lecture II DJGPhD 19 April 2021
The Immuno-Epigenome Contribution to Aging Foundation Lecture I. DJGPhD 18.4.21
T lymphocyte caveolae and the efficiency of effector cell differentiation. DJGPhD 4.4.21 Authentic Biochemistry
Involving Instanence. A Philosophical Episode on Authentic Biochemistry. DJGPhD 31 March 2021
Caveolae and Alzheimer's Disease. The Micro-vasculature Paradigm: Endothelial Cell Corruption in the CNS Authentic Biochemistry . Dr Guerra. 26 March 2021
Lipoprotein synthesis, turnover and trafficking in concert with caveolae-mediated lipid transport. Dr Dan Guerra Authentic Biochemnistry. 25.3.21.
Condensed Bioenergetics : Dr Guerra Drives the Electron Transport Chain via Standard Oxidation Reduction Potentials. 21.3.21
Landing on epithelial-mesenchymal transition and T lymphocyte selection to explore Senescence-Associated Cancer-like Stem Cells. DJGPhD 20.3.21
ADP- Glucokinase is essential for T lymphocyte activation and pro-inflammatory cytokine synthesis and secretion. DJGPhD. 19.3.21
The control of C flux in the liver, pancreas and CNS are coordinated: Potential Axis for Immuno Senescence X Intermediary Metabolic Regulation.Authentic Biochemistry . 15 March 2021. DJG PhD.
The pyridoxal phosphate contribution to amino acid metabolism and neurotransmitter turnover Dr Guerra Authentic Biochemistry 10 March 2021
Reactive Oxygen and the gamma-glutamyl cycle for GSH redox biochemistry and the prolegomena of neurodegeneration. DJGPhD 09March21'
Deacylation regulation of amino acid catabolism as a source of multiple bioenergetic and discrete excitotoxicity phenomena. DJGPhD . 03March2021
Amino Acid Catabolism via Sirtuins Modulation and the Redirecting of Hepatic and Intestinal Intermediary Metabolism. Dr Guerra Authentic Biochemistry. 02 March 2021
Sirtuins obtain a significant role in mitochondrial metabolism linked to caloric restriction and cancer. Dr Guerra. Authentic Biochemistry.26.02.21
Thermodynamics and regulation involving lipoic acid biochemistry of the classical 2-oxo acid dehydrogenase complexes. Dr Guerra 23.02.2021
Physical Biochemistry of Free Energy Transfer for Membrane Transport of Molecules and Ions.Dr Dan Guerra 19 Feb 2021
Membrane Proteins 1 Mini Lecture Dr Guerra 19 Feb 2021
Application of the Principle of Sufficient Reason to Biochemical Thermodynamics. Dr Dan Guerra 13 February 2021
Cell Cycle kinase inhibition may improve healthy cardiac aging while promoting global tumorigenesis. Authentic Biochemistry 10Feb2021 by Dr Guerra.
Adipokine Update Lecture 2. Authentic Biochemistry Podcast. Dr. Dan Guerra Published 06 Feb 2021
Adipokine Mini Review I Daniel J. Guerra, PhD. 03 Feb 2021 Authentic Biochemistry Podcast Publications.
Neuropeptide Y and the POMC neuronal antagonism in feeding behaviour maps onto fear conditioning. Dr. Dan Guerra 28 January 2021
Neuropeptide Y and the fear conditioning response: are aging and obesity prodromal to anxiety and cognitive decline? Daniel J. Guerra PhD. Published 25 January 2021
Corticotropin Releasing Factor and the Monoamine Fear Response in Aging. Sequence II. The reverse learning scenario as cognitive redistribution of neural transmission valency. DJGPhD.21.01.2021.
The Corticotropin Releasing Factor and the Somatosensory Catecholamine Circuit in ExtraDimensional (attentional) Shifting. Dr Guerra 20 Jan 2021.AB.
Aging-associated SASP vs. MiDAS is a contrarion trade-off that may lead to neurodegeneration and autoinflammation vs tumorigenesis and heart disease respectively. Dr. Dan Guerra.17 Jan 2021. AB
An Immunological Distinction between Senescence linked Secretory Phenotypes: SASP vs. Midas. Dr. Dan Guerra. Authentic Biochemistry 16 Jan 2021
The stress-induced Neural Network tracks Kantian Epistemology through characteristic action potential and neuromodulator/neurotransmitter phenomenology. Dr Guerra 13 JAN 2021.
Fear and Aging associated with neuronal conditioning and synaptogenesis via corticotropin releasing hormone. Dr. Dan Guerra; Authentic Biochemistry 13 JAN 2021
Fear associated Corticotropin Releasing Factor and the Immune response are linked to CNS neutral Sphingomyelinase I. Dr Dan Guerra 09 January 2021
Glycolysis is inhibited in T cells when Glucose 6 P non-competitively inhibits hexokinase after GLUT1 uptake of serum glucose:Setting the stage for lipogenesis.
The Porosomal complex and complex lipid interconversions organizing the transport and secretion of cytokines after T cell Receptor Activation by APC's
Inhibitory PFK1 palmitoylation is facillitated by Acid Sphingomyelinase. Daniel J. Guerra, PhD. Authentic Biochemistry Podcast 02 January 2021
T lymphocyte maturation and memory cell accumulation are differentially mediated by sphingomyelinase and protein palmitoylation. Dr Dan Guerra. 01 Jan 2021
Tumor cells and T lymphocytes carry forward initially similar and subsequently distinct bioenergetic regulation through AMPK. Dr Guerra Authentic Biochemistry 30 Dec. 2020
T cell metabolic Dialectics : deriving bioenergetic supremecy from glycolysis through fatty acid and lipid synthesis to ultimate fatty acid oxidation and ATP generation. Dr Daniel J. Guerra
On the Concept of Neuro-Correlation: A Theoretical Essay. Dr. Daniel J. Guerra . Authentic Biochemistry. 25 December 2020
T Cell signal transduction involves kinase and transcription factor mediated expression of bioenergetic ensemble gene products. Dr DJ Guerra 23 December 2020
From Glucose to Triacylglycerol in the developing T lymphocyte. Dr Daniel J. Guerra. Authentic Biochemistry 21 December 2020
The Misguided Linkage of Potentially Ablating Aging -Associated Metabolic Syndrome by tracking NAD+ serum levels. Dr. Daniel Guerra. 17 December 2020.
Intermediary metabolism plays an essential role in immune cell activation that may lead to tissue degeneration, lipid accumulation and oncogenesis in the aging human. Dr. Guerra. 14 December 2020.
Further Inquiries into The Immune System and The Aging Central Nervous System: The PDH/LDH/PDHK1 Axis. Dr. Dan Guerra 13 December 2020.
What T -cell Acute Lymphoblastic Leukaemia and Senescing microglial CNS disease have in common relate to Notch and Glucocorticoid signaling. DJGPhD 07 December 2020
Dr. Guerra interrogates Notch signalling in T lymphocte early development as prolegomena to immunodystrophy obtained with aging. 05 Decemeber 2020
From Bioenergetics to Cardiac Function and Thymocyte differentiation in the Aging Population. Dr. Daniel J. Guerra 02 December 2020.
Dr. Guerra herds the Hippo Pathway into T lymphocyte mediated autoimmune disease and cancer in the aging human Authentic Biochemistry 16 November 2020
T cell receptor excision circles (TRECs) are generated in the thymus and are potential indicators of acquired immune disorders in neuropsychiatry and senescence.
Dr. Guerra explains the ID2 HLH pseudo transcriptional corridor in leukemia and aging. 11 November 2020
Multiple Transcription Factor functional integration from immune cell lineages coordinate gene expression that maintains responses to intestinal infection during aging
Transcription Factor NFil3 tracks the circadian clock to microbiome linked immune cascade in the gut. Dr. Daniel J. Guerra 09 Nov. 2020
Dr Guerra illustrates that NFIL3 represses genes by recruiting Sirtuin 2 and G9a histone methyltransferase eo ipso regulating diverse biological processes,
The Circadian clock and the Acquired Immune Response coordinate at the event of transcription factor mediated aging phenotype. Dr Daniel J. Guerra
Animals have adapted behavioral responses corresponding with light and temperature events to respond to and anticipate basic bioenergetics due of heterotrophy. Authentic Biochemistry . 28/10/2020
While Melatonin binding to the MT1 and MT2 receptors may benefit aging via suppression of oncogenic gene expression and enhancement of the SCN sleep wake cycle, receptor loss occurs with senescence.
L-TRP is precursor to MEL and NAD ;Mel regulates Sirtuins which Perform DSB repair; NAD metabolism after SIRT activity yields PAR for SSB repair. DJGPhD 21 Oct 2020.
The Association of NAD+, Melatonin, &Sirtuins via DNA Damage Repair and Epigentic Chromatin Remodeling with Immunosenescence is evident
DDR and the roles of Sirtuins and the NAD metabolic paradigm in aging. Published by Authentic Biochemistry Dr. Daniel J. Guerra 19 Oct 2020
Dr Guerra presents :"Deacetylase Agency in NAD+ and ADP Ribose Metabolism as the Equipoise for Cell Fate In Aging and Disease" 14 Oct.2020
Dr Daniel J. Guerra of Authentic Biochemistry lectures on Senescence in Human Aging: The Sirtuin Intrusion
Dr. Guerra obtains a dialectical analysis of the pineal hormone melatonin in deacetylase-mediated Respiratory disease and aging
Dr. Daniel Guerra presents Immuno Diaeventontological Framing of the Aging Human IV: SASP to cGAS via Melatonin
Dr. Guerra finds that the tumor-promoting and suppressing biochemical phenotypes of senescence are phenomenologically contrarion and thus physiologically compatible
Is cancer. or survival-achieving chemotherapy to treat early-onset tumorigenesis, linked to late in life senescence and human aging? The CD8+ T lymphocyte link.
Dr Guerra suggests targeting senescence as a means to alter the rate of aging is contrarion to healthy outcome because of derepression of tumorigenesis.
Senescence and Aging Relative to T lymphocytes may be linked to chemotherapy of testicular cancer and underlying cell cycle-CD transcriptional mutations.
Thymic involution-associated naive cd4+/cd8+ Tcell differentiation as observed in care-giver neuropsychological conditioning toward non-chronological immunosenescence.
The teleology of Thymus mediated T regulatory cell clonal elimination and expansion via membrane associated receptor ligand interactions with innate and lymphocyte linneages. Dr Daniel J. GUERRA
Dr Guerra presents: The Agency of the Immune System Treg Lymphocytes in Senescence and Human Aging. Authentic Biochemistry Podcast.14 September 2020
Glucocorticoid Associated Naive Treg Differentiation and the Role of T Memory and Treg Sub-populations in Aging and End Stage Renal Disease
Innate Like Lymphocyte and T Regulatory Cell Modulation against a backdrop of Immunostimulatory Effectors 01 September 2020.
T lymphocyte and MVA pathway cross-talk in Breast Cancer, Lymphomas, Leukemias, CVD and aging. 24 August 2020
The Sterol Response Element Binding Protein expression, cellular translocation and transcription factor pathways in T cell activation. 18 August 2020. by Dr Dan Guerra
Dr Guerra lectures about Chronic Genomic Instability as a means to an end called senescence. Published 06 August 2020.
Dr Guerra discusses canonical Programmed Cell Death. Published 05 August 2020
The Aging biochemical landscape as associated with chromatin organization and the alteration of cell cycle dynamics leading to the Senescence Associated Secretory Phenotype
Dr Guerra discusses how Isoprenoid metabolism is linked to T cell activation via glycolysis and glutaminolysis. 02 August 2020
Dr Guerra discusses the mTORC -AMPK axis and the control of the rate of aging as central to the slow growth hypothesis to longevity. 01 August 2020
Dr Guerra discusses aging associated oxidative phosphorylation, gluconeogenesis, NAD+ sirtuin activity and telomerase. 30 July 2020
The Categorical Logic of Aging Systems as Influenced by Nutrition and the Introduction of Pharmacotherapeutics that Target Disease. Lecture VI. Published 27 July 2020.
The triad of biological auto-oxidation and the progress of aging as sine qua non to pathology. Published 26 July 2020.
Reactive oxygen is generated in biological systems leading to a physiological transit to senescence. Published 24 July 2020
The oncogenic intermediary metabolic corruption as contrarion ontology to aging. Published 24 July 2020.
Biochemical/Physiological Paradigms of Aging and Tumor Metabolism: the classical Warburg Aerobic Glycolysis and Krebs Cycle Corruption. 21 July 2020.
Dr Guerra starts a series on the biochemistry and physiology of human aging and the ontology of sequential phenomenon in living systems. 19 July 2020.
Neutrophil Elastase and the extracellular trap mediated hyperinflammatory response leading to pulmonary edema, Na+ hyperabsorption: linkage to coronavirus .
Neutrophil elastase-mediated pulmonary disease including Cystic Fibrosis, RDS, COPD and viral pneumonia 10 July 2020
A Narrative on the Nature of Belief as Universal within Knowledge yet Regularly Discounted in the Scientific World View. 09 July 2020
Serpins and the Neutrophil Extracellular Traps in Respiratory Distress and the Coronavirus. 08 July 2020
Dr Guerra examines proteases and protease inhibitors in ovarian and hepatocellular cancers and their pathobiochemical mechanisms. 03 July 2020.
The Role of Alpha anti-trypsin in the IL-1 pro-inflammatory cascade. 30 June 2020
SERPINs and the Acute Phase Response in the Pathophysiological State. Dr Dan Guerra, 29 June 2020
Dr Guerra Presents: Serine Protease Inhibitor Biochemistry in Human Health and Disease I. 25 June 2020
Dialectical Event Ontological Analysis of the Scientific Method as Prolegomena to a Recap of PEDF in Hepatocellular Carcinoma
Dr. Guerra presents: Contrarion opposition of PEDF in Tumor progression explained via dyslipidaemia and corruption of AMPK mediated control. 12 June 2020.
Dr Guerra's second lecture on T2D and its link to Obesity plus a bonus Clinical Misdiagnosis Study Question Review. 31 May 2020
Dr Guerra discusses Obesity-linked Type 2 Diabetes and clinical manifestation of the disease
Nutritional biochemistry and the obesogenic induction of insulin resistance and type-2 diabetes. Dr Daniel J. Guerra. 25 May 2020
Obesity and pathophysiological Implications including hyper-Immunity, increased susceptibility to serious infection and high-mortality disease.
Basic Endocrine Hormone Nomenclature and physiological biochemistry. Authentic Biochemistry 14 May 2020.
General Hormone Lectures II. The Hypothalamic Pituitary Axis. Dr Daniel Guerra. 05 May 2020.
General Human Hormone Physiology and Biochemistry Lecture I. Published by Dr Daniel J. Guerra. 04 May 2020
From Hypothalamic POMC to Palmitate and back again: Lipid Metabolism needs to Be Authenticated. Dr Dan Guerra. 28 April 2020.
Chapter V Immuno Endocrinology of Disease Dr Dan Guerra Authentic Biochemistry Podcast 27 April 2020
Request to check out my video lectures and subscribe to my podcast and YouTube Channel; This will add tremendous excitement and freedom to your day!
ASM-generated Ceramide Lipid Rafts and the Fatty Acid Transport Protein in the Hyperimmune Disease Response.
How do Sphingolipids associate with SSRI's to offer advice to Pharmacologists working on Coronavirus?
Dr. Guerra uses Logical and Scientific Principles to Perform a Dialectic On the Validity of COVID 19 Corona virus Pandemic. 23 March 2020.
Dr Guerra's Epistemology and Metaphysics informing a Scientific World View III. Recorded 20 March 2020.
Dr. Guerra's Epistemology and Metaphysics of a Scientific World View. Part II. 15 March 2020.
Dr. Guerra Introduces his epistemology and metaphysics that ground his scientific world view. 11 March 2020
Dr. Dan Guerra further discusses Ceramide and Sphingosine Mediated cell fate in Pathobiochemistry IV. March 04, 2020.
Dr Guerra presents today's podcast: Lipid –Associated Pathobiochemistry III. March 3 2020
Dr.Guerra authenticates evidence in lung Inflammation and associated resident macrophages in disease. 01 March 2020
Sphingolipid linked Coronavirus, Neurodegenerative, Neuropsychiatric and Inflammatory disease.
Dr Guerra examines Sphingolipids as mediators of Inflammasome Formation and Potency in Coronavirus
Authentic Biochemistry examines the epidemiology of the Novel Coronavirus Infectious Pneumonia of 2020. Episode II.
Dr Guerra presents the molecular organization, pathology, and transmission of the Novel Coronavirus Infective Pneumonia (NCIP). I.
Lupus Autoimmune Disease involves a specialized set of plasma and T cell lineages: From Dr. Dan Guerra 28 January 2020.
Dr Guerra explains how folic acid, homocysteine, and ceramide apprehend the pro-inflammatory neurodegenerative paradigm
Part III. Autoimmune Disease : essential background and cellular dynamics. Dr Dan Guerra
Dr Guerra brings the autoimmune disease discussion into view. 31 December 2019
T lymphocyte mediated autoimmune diseases as arising from immunological networking Dr. Guerra . 18 December 2019
T lymphocyte mediated auto inflammation from Dr. Guerra's Authentic BIOCHEMISTRY
Episode 2 of Authentic Biochemistry Foray into Epigenetics. Dr Dan Guerra. 01 November 2019
Lecture 1 on General Epigenetics from Dr Guerra of Authentic Biochemistry on 29 October 2019
Dr Dan Guerra provides a Leptin Coda
The Adipokine Leptin in Lupus, Osteoporosis and Glioma
The Homeostatic Roles of Leptin in Obesity and Disease: the adaptive biochemical evolution and dysfunction of lipid homeostasis
Leptin Molecular Endocrinology #2 Dr Guerra further explores the adipokine-mediated CNS.
Leptin's critical role in the HPA hormonal axis: a saturating overview 22 Sept 2019 DJGPhD
Primer on Omega 6 and Omega 3 Long chain polyunsaturated fatty acid metabolism in humans with Clinical Event Ontology
Dr Guerra provides an in-depth interrogation of lipid metabolism of omega three fatty acids and their complex roles in controlling inflammation.
Do Omega three fatty acids ameliorate obese adipose derived inflammation via a T cell response?
Dr. Guerra finishes the Treg lectures by drawing upon on a transcription factor molecular thread of Ariadne to deliver T cell lineage architechtonics.
Dr Guerra reports on evidence that Treg cells are negatively controlled by Nfil3 via inhibition of FOXp3 transcription while activating Th1 and Th2
Dr Guerra moves onward through the T cell lineages to an event ontology for Treg Stimulation/Activation and Stabilization IV.
T-regulatory Transcription Factor modulation directs lineage adaptation and potency in a pro-inflammatory environment
Innate lymphoid cells and the frank T lymphocyte family as controlled by cytokinogenesis, co-stimulation, and Tregs. Part I.Dr Dan Guerra
Prolegomena to T regulatory cell transcriptional control mechanisms and a request to subscribe from Dr. Guerra
The fate of the mammalian CNS is a matter of lipid sponsored program cell death
Dr. Guerra provides a clinical discussion of HCC pathogenesis and treatment including the role of HCV. 03 July 2019
SERPIN mediates transcriptional control over pro-tumorigenic pathways including a phosphatidyl inositol 1,3 kinase delta mediated mechanism.
Dr Guerra admits Serpin mediated cancer ablation is multivalent and pharmaceutically treacherous
Introduction to Proteases and Protease Inhibitors as Prolegomena to Specific HCC pathophysiology
HCC Episode VII. Dr Guerra tackles the pathogenecity of the serine proteinase inhibitor paradigm . 08 JUne 2019
Hepatocellular Carcinoma Pathobiochemistry Chapter/Lecture V from Dr. Daniel J. Guerra. Authentic Biochemistry.28 May 2019.
Dr Guerra Characterizes How Glycolytic Enzymes Proxy Oncogenically in Prodromal Hepatocellular Carcinoma. 26 May 2019
Dr Guerra introduces the pseudo-paradoxical irony of Pyruvate kinase M2 expression toward the biochemical Aetiology of HCC
Authentic Biochemistry Podcast. Dr. Dan Guerra presents Heptaocellular Carcinoma Part II: Metabolic and Signal Transduction Cascades
Dr Guerra Starts his podcast lecture sequence on Obesity and Hepatocellular Carcinoma. Series session#1
HDAC 4 is a positive player in ALS muscle since it is not a functional histone deacetylase: The complexity of motor neuron disease reveals not-so-subtle differences in protein function
Dr Guerra continues : Glutamate induced ferroptosis involves lipid peroxidation and ceramide production leading to an inflammatory response in neurodegeneration
Dr Daniel Guerra introduces a novel PCD pathway- ferroptosis- that is linked to excitotoxicity and lipid peroxidation leading to neurodegeneration. Part I
Authentic Biochemistry #3. Dr Guerra verifies the evidence to a future biochemical prolegomena for Alzhiemer's Disease
The Diaeventontology of Biological Systems
Introduction to Authentic Biochemistry Podcast