All Episodes

Integrating Cleavage, Deprotection, and TFF: How Asahi Kasei’s THESYS® Platform Is Reshaping Oligonucleotide Manufacturing

Advancing Closed-System Performance: How CPC’s MicroCNX® Connectors Enable Scalable Cell and Gene Therapy Manufacturing

Inside ATLAS – Transforming Surfactant Monitoring in Bioprocessing

From Storage Tanks to Smart Systems: The Evolution of Buffer Preparation

Unlocking the Potential of Induced Pluripotent Stem Cells: Innovations, Challenges, and Future Directions

Accelerating Bioprocess through Digital Transformation: A Strategic Path Forward

The Key to Biologics Success: Why Developability Assessments Matter in Antibody Discovery

New Cell Culture Select Tool Simplifies Cell Culture Selection for Researchers

Revolutionizing Cellular Therapies: How Automation is Transforming the Industry

Pioneering Access and Innovation: The Future of Cell and Gene Therapies

How AGC Biologics received approval from both US and European regulators for commercial manufacture of Lenmeldy – A cell-based gene therapy

How Real Time Titer Measurement And Monitoring Is Advancing Bioproduction Across Multiple Applications

Advancements in Buffer Management and Single Use Inline Buffer Formulation

Executing Efficient Scale-up and Large-Scale Viral Vector Manufacturing

Advancements in Cell and Gene Therapy Stirred-Tank Bioreactor Suspension Culture

Sangamo’s gene therapy product candidate for Fabry disease shows continued tolerability and promise as an alternative to Enzyme Replacement Therapy

Single-use Mixers – Ensuring the Customization, Scalability and Supply Required for Success

New online Gene Therapy Academy offers great resources to support scaling up from lab to production scale

Increasing Liquid Chromatography Efficiency with Fully-controlled Binary Blending

Biomanufacturing Quality Management Systems – A holistic approach

Flexible single-use mixers are key to achieving a next level mixing experience and reducing delivery lead times

Manufacturing high concentration mAbs challenges and solutions

A Guide for Navigating the Single Use Technology Supply Chain

Upstream and Downstream Processes – A Holistic View

Optimizing Process Development Early – A critical factor in successful viral vector scale up and large scale manufacture

Using End-to-End Integrated Solutions to meet the High Demand for Viral Vector GMP Manufacturing

Streamline the ADC Path to the Clinic with One-stop Drug Development and Critical Technology Advancements

The benefits of using a single-source for discovery, development and GMP manufacture of antibody drug conjugates and other novel bioconjugates

Increasing speed and efficiency of biotherapeutic drug development with stable pools

Addressing the increasing demand for single-use technologies and supply chain shortages with future proof systems

Implementing Adherent Cell Culture Technology for Cell Therapy Bioprocess

Evolving Beyond the Status Quo with Next Generation Buffer Prep Solutions

Integrated Freezing Solutions to Minimize Risk and Preserve Product Quality

Enabling process development for continuous bioprocessing: Answering the call for small scale tools that are fit for purpose

The CHO Cell Line – From Reliable Workhorse to State-of-the-art Protein Powerhouse

The Secret Ingredient in Your Gene Therapy Success Recipe

3D cell culture bioreactor system for growing and maintaining spheroids and organoids with the structure and function of in vivo cells

Optimizing Protein Expression and Purification using Mass Spectrometry Analysis

New Lab Set Up – Best Practices for a Successful Start

Demystifying the FBS Selection Process – A guide for evaluating product quality, origination and cost consideration

Reducing Fill Risk in Drug Product Manufacture Utilizing New State-of-the-Art Systems and Platforms

The Challenge of Staying Current with Regulatory Changes – How one company is providing a solution

Computer Aided Biology Platform Helps Companies Meet the Challenges of 21st Century Biomanufacturing

Balancing Risk, Cost and Speed During Clinical Development While Still Maintaining Quality

Solving the challenges of standardizing cell counting to ensure reproducibility in experiments, assays and manufacturing processes

A Look Towards the Future of 3D Cell Culture – A panel discussion

Multistem – A Stable, Off-the Shelf Regenerative Medicine Has Demonstrated Promise in Treating Patients with Acute Respiratory Distress Syndrome or ARDS

Bi-Specific Antibodies – The development, manufacture and promise of these cutting-edge therapeutics

Rapid At-line Media Analyzer Speeds Process Development by Eliminating Analytics Bottleneck

Non-Animal Origin cell culture supplements and manufacturing aids for biologics manufacturing

Mesenchymal Stem Cell Culture – Challenges and solutions for isolation, expansion and maintenance

CryoVault Freeze and Thaw Platform Provides a Scalable, Robust and Single-Use End-to-End Solution for Bulk Drug Substance

Generating actionable data and analysis in complex models using live-cell analysis

Improved gene therapy analytics permit monitoring of critical quality attributes and increased manufacturing efficiency

New Advancements in Cell and Gene Therapy Implementing Precision Medicine

Live Cell Analysis for Neuroscience Research

Using 3D cell-based human liver microtissue models in predicting adverse effects caused by chronic exposure to engineered nanomaterial

Raw Material Quality – Identifying and Mitigating Variation

Antibody Drug Conjugate (ADC) Development and Manufacturing Challenges and Solutions

Mustang Bio’s gene therapy has tremendous potential to cure XSCID or Bubble Boy Disease based on study results from St. Jude

Successful Methods for Perfusion Process Optimization

How Live Cell Analysis Technology is Meeting the Needs of Ever Evolving Advanced Cell Models

Innovative vaccine manufacturing enables the delivery of vaccines to the developing world

Optimizing Fed Batch Culture – Developing New Tools and Methods to Improve Production

Using cell culture models of endocrine resistance to improve triple positive breast cancer treatment options.

Integrating bioprocessing steps to improve efficiency and reduce cost

Expediting cell and gene therapy workflows

A Road Map for Efficient Fed-Batch Cell Culture Optimization

Viral Vector Manufacturing for Gene Therapy

Key Considerations in Gene Therapy Manufacturing for Commercialization – A panel discussion

Closed System Cell Therapy Manufacturing – Moving from the lab to clinical and commercial production

Successful Mesenchymal Stem Cell Manufacturing for Cell Therapy Applications

Bioprocessing Technologies for Stem Cell Therapy

Cell Therapy Manufacturing – Opportunities and Challenges

Novel Technology Enables Encapsulated Cell Therapies Without Triggering Fibrosis

FBS – It’s Not All Created Equal – What Consumers Need to Know

Do You Have to Sacrifice Antibody Titer for Quality? Employing cell biology to get the best of both worlds

Implementation of Single-use Bioreactors for Microbial Fermentation is Easier Than You Think

Single-use Bioreactors for Fermentation – It’s now a reality that deserves consideration

Bioengineered Organ Implants Poised to Change Treatment Paradigms in Esophageal Cancer

Improving lab productivity and reproducibility by taking a fresh look at existing workflows and protocols

Smart Cell Culture Monitoring – Transforming the way we look at cells in culture

Enabling Vaccine Manufacturing and Viral Vector Production using the iCELLis – a single-use, automated, and closed manufacturing platform