All Episodes

Ep.136 – Convenience vs. Care: Rethinking IV Push Cefepime in Critically Ill Pseudomonas Patients

Ep.135 – Bugging Out: Antimicrobial Updates in Sepsis Care

Ep.134 – When Antibiotics Get Lost in Transition: Errors Moving from Hospital to Skilled Nursing Facility

Ep.133 – Beyond the Cardinal Symptoms: Evaluating the Latest Antibiotic COPDE Treatment Criteria

Ep.132 – The Science of Antibiotic Decisions: Physician Antibiotic Choices for Community Infections

Ep.131 – When a UTI Isn't Just a UTI: Why the Right Diagnosis Changes Everything

Ep.130 – Bugs in the Belly: Optimization, Dosing, and Better Outcomes

Improving Antibiotic Prescribing for Acute Bacterial Sinusitis in 7 Seconds

Navigating Vaccine Changes: Insights and Updates from the Vaccine Integrity Project

Ep.127 – Narrowing the Spectrum: De-Escalation Without Compromise

Three Stewardship Interventions Hospitals Can Steal for 2026

Ep.125 – Stewardship in Action: Short Courses and Oral Transitions

Ep.124 – Words Matter: Tackling Fluconazole Overuse

Down with Cefdinir! Cefdinir versus Cephalexin for uncomplicated UTIs

A Global Perspective on Antimicrobial Resistance

Ep.121 – PEP Talk: Navigating the New HIV Occupational Guideline

Antibiotic Dosing in Obesity: What the Largest PK Review Reveals

Ep.119 – New Rules for Old Infections: What the DOTS Trial Tells Us

Ep.118 – Combatting unnecessary ASB treatment through diagnostic stewardship – which approach works?

Ep.117 – Nurse-Driven PEN-FAST Allergy De-labeling

Ep.116 – Cascade Reporting Under the Microscope: Two Sides, One Debate

Ep.115 – Septic Shock and AKI: Do we still need to worry about piperacillin-tazobactam?

Ep.114 – Procalcitonin in Practice: Evaluating Its Impact on CAP Management

Ep.113 – Are You Ready for It? Assessing Cephalosporin Allergies with the CEPH-FAST Score

Ep.112 – (Re)moving the needle: implementation of an institutional IV to PO treatment guidance for bone and joint infections

Ep.111 – Sole Support: Using Clinical Decision Support Solutions to Improve Care for Patients Inpatients with Diabetic Foot Infections

SBP Prophylaxis: What We’re Doing, Why We’re Doing It… and Should We Keep Doing It?

Short and Sweet: Is short course appropriate for uncomplicated Streptococcal bacteremia?

Ep.108 – Guideline-Driven Success: Standardizing Care for Gram-Negative Bloodstream Infections

Ep.107 – Blood Culture Stewardship: Post Shortage Lessons

Ep.106 – Less is More-Dazole? Metronidazole twice daily versus three times daily for B. fragilis bacteremia

Ep.105 – Antibiotic De-escalation in Sepsis Patients

Ep.104 – Testing Troubles: Navigating C. difficile confusion

The BALANCE Trial: 7 vs 14 Days for Bloodstream Infection

Ep.102 – Bug in a Mug: Should we be worried about hospital coffee machines?

Ep.101 – Decoding DxEx: the CDC Core Elements of Hospital Diagnostic Excellence

Ep.100 – Episode 100: A Celebration of Stewardship

Ep.99 – Unexpected Findings: Ertapenem in Surgical Prophylaxis

Ep.98 – Choosing Wisely: Antibiotic Decisions in Outpatient Community-Acquired Pneumonia

Ep.97 – A Multicenter Retrospective Study Evaluating Intravenous to Oral Antibiotic Stepdown for Uncomplicated Streptococcal Bacteremia

Ep.96 – Update Alert! IDSA Resistant Gram-negative Guidance Version 4.0

Waiting on a Culture: Impact of pharmacist-led microresult follow-up post-discharge

Ep.94 – Rethinking Daptomycin Dosing: New data on fixed dose daptomycin

Ep.93 – Return of the Penicillin Allergy Label

Ep.92 – Is One Better Than the Other? Analyzing surrogates for oral cephalosporin susceptibilities

Is ID the Consult of Fear?

Ep.90 – It Goes On and On and On: Reviewing the new RCT for Continuous infusion vs. Intermittent infusion Beta-lactams

Ep.89 – Infectious Disease Consultations: Can AI Really Replace Human Experts?

Ep.88 – Is the debate back?: A retrospective study in patients with sepsis who received piperacillin-tazobactam vs. cefepime

Ep.87 – BCI(De-escalation): The Impact of Rapid Diagnostics and Stewardship Intervention on Treatment of Contaminated Blood Cultures

Ep.86 – PEN-FAST and Furious: The efficacy of the PEN-FAST tool in de-labeling previously reported penicillin allergies

Ep.85 – The devil's in the defaults: the impact of eliminating default durations of therapy

Ep.84 – Navigating the LAByrinth: Updates in Antibacterial Susceptibility Testing

Ep.83 – Incorporating Adverse Event Feedback Into Antibiotic Stewardship

Ep.82 – Optimizing the use of the GI Panel and strategies to improve appropriate testing

Ep.81 – Which of Active vs Passive Response to Rapid Diagnostic Blood Culture Results

Ep.80 – Exploring the Microbiome: Pertinent details from a phase 1 study exploring omadacycline in healthy guts

Ep.79 – It’s All in the Dose: High-dose oral beta-lactams for bacteremic UTIs due to Enterobacterales

Ep.78 – Source Specific Sepsis Order Sets Lead to Improved Empiric Therapy in the ED

Ep.77 – Optimizing Outpatient Ordering

Ep.76 – Ending VAP: is vaporizing antibiotics the answer?

Ep.75 – Febrile Podcast: Being a Stewie

Ep.74 – Neurotoxicity vs Nephrotoxicity: A Look at the Comparative Safety of Cefepime and Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection

Ep.73 – Analyzing Antibiograms: Reassessing a major tool

Ep.72 – Hit me with your best shot! Tools to select the best empiric therapy in complicated UTIs

Ep.71 – Emphasizing Health Equity

Ep.70 – Can we FINALLY stop antibiotics in culture negative serious infections?

Ep.69 – Creating Impactful, Feasible, Actionable, and Measurable Stewardship Interventions

Ep.68 – Don’t be so Negative! A Look at GN-BSI in the US

Ep.67 – Rx for Success: Tackling Penicillin Allergy De-Labelling in our Hospitals

Ep.66 – The Necrotizing Soft Tissue Infection Conundrum: Vancomycin Plus Clindamycin vs. Linezolid

Ep.65 – Plagued by Probiotics?

Ep.64 – SSI Compendium Update

Ep.63 – Antibiotic Spectrum Scores

Ep.62 – Pip-Tazo: A Pancreatic Panacea?

Ep.61 – Antimicrobial susceptibility testing: An updated primer for clinicians in the era of antimicrobial resistance: Insights from the Society of Infectious Diseases Pharmacists

Ep.60 – Hydrocortisone in Severe Community-Acquired Pneumonia

Ep.59 – Prophylaxis Progress Report

Ep.58 – RSV vaccines coming: Its ok to be excited

Ep.57 – A Guide to Diagnostic Stewardship

Ep.56 – Let's take a mindful pause before treating bacteriuria in older adults

Ep.55 – Discordant C. diff testing results - to treat or not to treat?

Ep.54 – Stewardship Secrets: Optimizing carbapenem use in our facilities

Ep.53 – Spellcheck Stewardship: A Happy Holidays from DASON

Ep.52 – A Decade of Fluoroquinolone Stewardship

Review of the CDC's Antibiotic Use Report - 2022

Streptococcal Bacteremia and the Risk of Infective Endocarditis

Stewardship Practices at US Hospitals

The DETOURS Study - A Chat with the Author

Ep.47 – A Novel Metric to Measure Antibiotic Use and Spectrum of Activity

Ep.46 – SSI Rates Among Patients Receiving Elective Colorectal Surgery with Beta-Lactam vs. Non-Beta-Lactam-Based Antimicrobial Prophylaxis

Ep.45 – Let's Talk About Surgical Prophylaxis

Ep.44 – Antibiotic Effects on the Gut Microbiome & Resistome: It’s Worse than We Thought - An Interview with Dr. Jennie Kwon

Ep.43 – Less is More: Reducing Unnecessary Antibiotic Use for Asymptomatic Bacteriuria

Ep.42 – A Chat With the Author: Network- and Health System-guided Stewardship

Ep.41 – Antibiotic Overuse and Stewardship at Hospital Discharge

Ep.40 – Reducing Antibiotic Use for Upper Respiratory Infections in Outpatients

Ep.39 – Stewardship Opportunities Upon Hospital Discharge

Ep.38 – If you have to: Non-antibiotic prophylactic treatment for recurrent UTI

Ep.37 – Outpatient Stewardship for UTIs: Reducing Fluoroquinolone Use

Ep.36 – Antibiograms for Escalation: What’s the Application?

Ep.35 – The Waiting Game: Time Between Blood Culture Sets

Ep.34 – The Role of the Antimicrobial Stewardship Program in Pandemic Response

Ep.33 – Oral Cephalosporins vs First-line Agents for Outpatients with Pyelonephritis

Ep.32 – Vancomycin Monitoring: Are We Below the Curve? A Discussion with Experts

Ep.31 – Systems Say Go: Assessing Antibiotic Prescribing After Removal of a Penicillin Allergy Alert

Ep.30 – Engaging Nurse Stewards

Ep.29 – Simplifying the Management of Neurosyphilis

Ep.28 – COVID Vaccines - Let's Keep Myocarditis in Perspective

Ep.27 – Molnupiravir – Finally, an Oral Option for Outpatients with COVID-19

Ep.26 – The Status of Antimicrobial Stewardship in the US

Ep.25 – Race to Start: Beta-lactams or Vancomycin First for Bacteremia?

Ep.24 – MSSA Bacteremia: Cefazolin, Final Answer

Ep.23 – Just for Men: An Update on the Management of UTI

Ep.22 – 7 Day Treatment Over 14 Days for Enterobacterales Bacteremia, Not Just Non-inferior Anymore!

Ep.21 – From the Front Lines: Impact of Handshake Stewardship in the ICU

Ep.20 – Addition By Subtraction: Optimizing Antibiotic Durations at Hospital Discharge

Ep.19 – Real Talk with DASON: COVID-19 Vaccines

Ep.18 – Ideas for Antimicrobial Stewardship in the ED

Ep.17 – Duration of therapy for Prosthetic Joint Infections, review of a potential game changer study with Dr. Ted Hendershot

Ep.16 – Metronidazole-associated Neurologic Events

Ep.15 – Estimated Clinical and Economic Impact of Reducing Blood Culture Contamination

Ep.14 – Preoperative Beta-lactam Allergy Intervention

Ep.13 – Strategies to Optimize Outpatient Antibiotic Prescribing for UTIs

Ep.12 – De-Escalation of Broad-Spectrum Antibiotics After Negative Cultures in Patients Admitted with Pneumonia – We Have Work to Do

Ep.11 – Short-Course Antibiotics: Best Practice Advice from The American College of Physicians

Ep.10 – Community Acquired Pneumonia: It's All About the Numbers

Ep.9 – Vancomycin vs Daptomycin – An Old Rival – The Battle Continues

Ep.8 – The Nose Knows: Using Nasal MRSA PCR to De-Escalate Vancomycin

Ep.7 – Discussing the DRIP Score

Ep.6 – Cefiderocol: Seeking Another Option for Serious Gram-Negative Infections

Ep.5 – Antibiotics for Appendicitis: Ready for Prime Time?

Ep.4 – Antimicrobial Stewardship Guidance for COVID-19 Patients

Ep.3 – COVID-19 mRNA Vaccine: Myths and Common Questions

Ep.2 – A Preview of the Upcoming Changes to the IDSA C. difficile Treatment Guidelines

Ep.1 – Optimizing Treatment for ESBL-Producing Pathogens