All Episodes

Liraglutide for heart failure, vasopressin for septic shock, President Barack Obama on US health care reform, and more

Radiotherapy for brain metastases, trends in C-sections and preterm birth, screening for skin cancer, and more

Burphenorphine for prevention of opioid relapse, gun law reform in Australia, cellulitis review, and more

HIV/AIDS Theme Issue

Who's practicing euthanasia and physician-assisted suicide?, clopidogrel for secondary prevention of stroke, a new treatment for Huntington disease, and more

SPRINT trial in older adults, escitalopram for depression in heart failure, post-critical care rehabilitation, diagnosis and management of diarrhea

A protein-based CVD risk score, trends in diet among US adults, herbal therapies for menopause, USPSTF colon cancer screening recommendations, and more

Aspirin for ARDS, comparative efficacy of weight loss drugs, review of temporal arteritis and polymyalgia rheumatica, and more

Trends in US adult and child obesity, selecting smokers to screen for lung cancer, screening for syphilis, and more

Endobronchial coils for COPD, timing of dialysis for AKI in the ICU, sodium excretion and CVD, neighborhood walkability, and more

Early EPO in preterm infants, esophageal changes with GERD, which oral anticoagulant for afib?, and more

Mammography reading order and breast cancer detection, treatment of adolescent ADHD, trial of macitentan for systemic sclerosis digital ulcers, and more

XRT for pancreatic cancer, web-based depression prevention, management of pancreatic cysts, and more

Sublingual immunotherapy for asthma, shift work and CVD, review of tick-borne illness, and more

PCSK9 inhibitors and statin intolerance, pembrolizumab for melanoma, CDC opioid prescribing guideline, and more

Managing agitation and infection in the ICU, does your patient have infectious mononucleosis?, and more

Noninvasive ventilation in the ICU, screening for COPD, Era3 for medicine and health care, and more

Non-drug treatment for back pain, child antibiotics and weight gain, requests for data sharing, and more

Inhaled xenon for neuroprotection after cardiac arrest, association between vaccine refusal and vaccine-preventable diseases, and more

Effects of naltrexone-buproprion on CV events in obese people, vitamin D for arthritis, predicting postconcussion syndrome in kids, and more

Perioperative statins for AKI, insulin glargine vs degludec/liraglutide for T2DM, visual acuity screening, and more

Evolving issues in Critical Care and Sepsis Theme Issue

Screening for autism, outcomes after hospital readmission, interstitial lung abnormalities and mortality, and more

Reducing inappropriate antibiotic prescribing in primary care, stroke rehabilitation, review of community-acquired pneumonia treatment, and more.

Dupilumab for chronic sinusitis, effects of acetazolamide on COPD ventilation duration, seafood intake and dementia, and more.

Trial of prenatal vitamin D for child asthma, welcoming the US Preventive Services Task Force to JAMA, screening for depression, and more.

Theme Issue: Death, Dying, and End of Life

Fecal transplant for C difficile infection, lung volume reduction coil treatment for severe emphysema, review of constipation, and more.

Lifestyle interventions for heart failure with preserved ejection fraction, safety of fluconazole during pregnency, new Innovations in Health Care Delivery series, and more.

Ovarian suppression during breast cancer chemotherapy, pain control for pleurodesis, neuroimaging for TBI, and more.

RBC storage duration, stem cell transplantation for Crohn disease, management of Graves disease, and more.

Theme Issue: Medical Education

Metformin for type 1 diabetes in obese adolescents, c-section deliveries and maternal-child outcomes, effect of OSA treatments on blood pressure, and more.

Photocoagulation vs VEGF inhibitor for diabetic retinopathy, ultrasound-guided PCI, global prevalence of low BMI in women, review of polyneuropathy, and more.

Prophylactic azithromycin for pediatric LRTI, PSA screening before and after USPSTF guideline recommendations, comparative risk of anaphylaxis with IV iron, and more.

Cardiovascular Disease Theme Issue

Endovascular thrombectomy for stroke, trends in prescription drug use in the US, HAART for HIV-infected children in South Africa, and more.

Tiotropium vs LABAs for asthma, comparison of IV fluids and noninvasive ventilation in the ICU, trends in US mortality, and more.

The American Cancer Society's 2015 Breast Cancer Screening guideline update, flexeril vs percocet for low back pain in the ED, safety of Tdap vaccination in pregnant women, and more.

RCT of physical therapy for low back pain, review of pericarditis, opioid use disorders in the US, and more.

Minimally invasive surgery for rectal cancer and diverticulitis, rehabilitation after immobilization for ankle fracture, long-term outcomes after carpal tunnel release, and more.

Treatment of agitation in Alzheimer disease, text messaging for CV risk modification, a newly approved PCSK9 inhibitor for dyslipidemia, and more.

Time Spent Outdoors and Development of Myopia in Children, Sex Differences in Academic Rank in US Medical Schools, Mortality After Hip Fracture vs Elective Hip Replacement, and more

Iron and malaria, advances in diabetes diagnosis and treatment, pushing the limits on neuroimaging, and more.

Aldosterone antagonism for diabetic nephropathy, genomic testing of children with autism and cancer, treatment of chronic sinusitis, and more.

Effects of exercise and supplements on cognition in older adults, mutation clearance and AML outcomes, and more.

LMWH for VTE in cancer, liraglutide for weight loss, e-cigarettes as a risk factor for smoking, advances in treating sepsis, and more!

Testosterone and subclinical atherosclerosis, CKD screening and definitions, postmarket surveillance of medical devices, and more.

Violence/Human Rights Theme Issue

Medicare and Medicaid 50th Anniversary Theme Issue

Avian flu vaccine adjuvants, bystander intervention for cardiac arrest, atrial fibrillation treatment, and more.

Guideline statin eligibility and coronary risk, cost-effectiveness of coronary risk thresholds, patiromer for hyperkalemia, managing polypharmacy, and more.

Diagnosis and treatment of venous thromboembolism, stroke and cognitive decline, mortality from combined CHD-stroke-diabetes, and more.

Cannabinoids for medical use, ICDs for patients with low ejection fraction after MI, PDE5 inhibitors and melanoma, early PDA screening and mortality in extremely preterm infants, and more.

Noninvasive ventilation for postoperative hypoxemia, antibiotics vs surgery for appendicitis, sources and areas of health development assistance, noninferiority trials, and more.

Americans With Disabilities Act 25th Anniversary Theme Issue

Preventing acute kidney injury with remote ischemic preconditioning, maternal antidepressant use and newborn pulmonary hypertension, a comparison of ACO and fee-for-service healthcare delivery models, and more.

Soy supplements for poorly controlled asthma, subclinical thyroid disease and fracture risk, copy number variations and cognitive phenotypes, and more.

Oral corticosteroids for disk herniation, amyloid in dementia, stroke prevention in atrial fibrillation, and more.

Medical Professionalism and Governance Theme Issue

Spores for prevention of recurrent C difficile infection; 2 studies of newer antivirals for HCV; and more.

Retrievable IVC filters for pulmonary embolism, ED-based suboxone for opioid dependence, genetic susceptibility to rheumatoid arthritis, and more.

Child Health Theme Issue: Autism, diabetes prevention, gene therapy, and more.

Maternal diabetes and autism, survival with bioprosthetic vs mechanical mitral valve replacement, dabigatran adherence, treatment of stroke, and more.

Folate for stroke prevention, bivalirudin during PCI for myocardial infarction, cancer risk by BRCA type and location, and more.

Oral antivirals for HCV/HIV coinfection, stent vs medical treatment for intracranial stenosis, a preliminary postexposure Ebola vaccine, and more.

Efficacy of post-PCI dual antiplatelet therapy by stent type, concordance in breast biopsy readings, NSAIDs and colorectal cancer risk, early imaging for uncomplicated back pain, and more.

Spotlight on Cardiovascular Disease: Outcomes following TAVR, LDL receptor status and diabetes risk, statin intolerance, NOAC dosing, and more.

An intervention to improve housing stability for homeless adults with mental illness, lorazepam before general anesthesia, the natural history of benign thyroid nodules, review of irritable bowel syndrome, and more.

Risks of combination NSAIDs-antithrombotics in patients with MI, vincristine-related peripheral neuropathy in children with ALL, management of patients with anticoagulation-induced intracerebral hemorrhage, kidney disease staging, and more.

Corticosteroids for pneumonia, varenicline for smoking cessation, eliglustat for splenomegaly in Gaucher disease, and more.

Iron after blood donation, creatine for Parkinson disease, BP lowering in type 2 diabetes, screening for melanoma, and more.

Spotlight on Surgery: Transfusion ratios in severe trauma, reasons for and review of hospital readmissions, NSQIP participation and surgical outcomes, and more.

Chlorhexidine bathing in the ICU, protocolized sedation for children with respiratory failure, MRI for prostate biopsies, C difficile review, and more.

ICSI use and outcomes, HSCT for multiple sclerosis, surgery for drug-resistant epilepsy, and more.

New JAMA series: Scientific Discovery and the Future of Medicine, CVD prevention and outcomes in a rural setting, asthma and OSA, and more.

Life expectancy in type 1 diabetes, HPV vaccination and demyelinating diseases, a review of traveler's diarrhea, and more.

Hypothermia for neonates, the medical home for children with chronic disease, metformin for type 2 diabetes, and more.

Aspirin for primary CVD prevention, HBV reactivation prevention, management of cognitive impairment, and more.

Medical Education Theme Issue: Maintenance of certification, ACGME duty hour reform and patient outcomes, and more.

New treatment for hyperkalemia, CAD screening in patients with diabetes, preventing kidney injury after cardiac surgery, and more.

Levofloxacin after renal transplant, preschool interventions and school outcomes, medical liability reform, and more.

Cardiovascular Disease Theme Issue

Clinical exome sequencing, hospice and health services use, treatment of syphilis, and more.

Metastatic melanoma treatment, nonobstructive CAD, primary care treatment of obesity, and more

Price, Cost, and Competition in Health Care Theme Issue

Trial of vitamin D for critical illness, vancomycin MICs and mortality from S. aureus, review of climate change and health, and more.

2014 Infectious Disease Theme Issue

Postdischarge virtual wards for high-risk patients, acupuncture for knee pain, review of clinical management of staph bacteremia, and more.

Decision support for genetic testing, US diabetes epidemiology, e-med packaging devices and adherence, and more.

Antenatal magnesium and school-age outcomes for preterm infants, LABA-ICS vs LABA alone for COPD, treatment of VTE and high cholesterol, and more.

Effect of darapladib on post-ACS events, colchicine for postpericardiotomy afib, sickle cell disease management guidelines, and more.

2014 Weight Management Theme Issue

Self-titration of antihypertensives in high risk patients, collaborative primary care for depressed adolescents, pain management in older patients, and more.

Financial incentives for circumcision in Kenya, effects of oximetry on bronchiolitis hospitalization, newborn screening for SCID, and more.

Effect of flexible sigmoidoscopy on colorectal cancer incidence, periop afib and long-term risk of stroke, treatment of hepatitis C, and more.

Screening and interventions for problem drug use in primary care, nutrition in the ICU, diagnosis of bladder outlet obstruction, and more.

2014 HIV/AIDS Theme Issue

Telecare for chronic pain in primary care, hydroxychloroquine for Sjogren syndrome, stroke incidence and mortality in the US, and more.

Surgical approaches to gallstone migration, antibiotics after cholecystitis, varenicline with vs without NRT for smoking cessation, and more.