All Episodes
Paper Talk — 957 episodes
970-Spatial 5mC-seq Profiling of Embryos and Decidua
969-Plastic Architecture of Brain-Wide Astrocyte Networks
968-White Matter Lesions Drive Grey Matter Inflammation
967-Early Fibrotic Niches Establish Tumour-Permissive TME
966-QuadPE: Platform for Large Genomic Insertions
965-SIDISH: In Silico Perturbation for Precision Medicine
964-Genetic and Somatic Trade-offs in Ageing and Mortality
963-RAS-GTP Inhibition in KRAS Mutant Cholangiocarcinoma
962-Engineered Metabolic Modulation of Gut-Liver-Brain Axis
961-Global Genetic Interaction Network of the Human Cell
960-Spatiotemporal Maps of Whole Mouse Embryos
959-The Dynamic Architecture of Meningeal Immunity
958-Single-Cell Spatial Atlas of Human Skin Anatomy
957-Mapping Plastic Astrocyte Networks Across the Brain
956-scAgeClock: Model for Single-Cell Human Aging
955-ProAPOBEC: Enhanced in vivo RNA Base Editing
954-How autopolyploid genomes return to a diploid state
953-Early Fibrotic Niches in Lung Tumour Initiation
952-Deconstructing the Memory Engram
951-Precision Neuroimaging of Human Circuit Responses
950-UBQLN2 Links Proteostasis in Neurodegeneration
949-Restoring Bimanual QWERTY Typing with Neuroprosthesis
948-Epigenetic Memory of Developmental Programs in Adult CNS
947-Competitive Interactions Shape Mammalian Brain Network
946-Spatiotemporal in developing postnatal prefrontal cortex
945-Decoding CNS Injury-Responsive Enhancers
944-Lecanemab attenuates Alzheimer’sAβ pathology
943-The Mouse Brain Atlas of Dendritic Microenvironments
942-Oxidized Phospholipids in Chronic Neurodegeneration
941-Mapping the Human Allostatic–Interoceptive System
940-Spatial Organization of Striatal Neuron Morphology
939-Hypothalamic Leptin Receptors Counteract Anxiety
938-C9orf72 Repeat Expansions Impair Microglial in ALS
937-Region-Specific Drivers of Human CSF Mobility
936-Psychedelics Dissociate brain function
935-Muscle EVs and miR-126 Regulate TDP-43 and NMJ Integrity
934-Plaque-Associated Microglia in Alzheimer’s Disease
933-Deep Drainage and White Matter Decline in Aging Brain
932-Thalamocortical Connectivity of Cortical Plasticity
931-Gyrencephalic Niche for Postnatal Interneuron Migration
930-Spatial Landscapes of Human Glioblastoma
929-Mapping Neuronal Fate in Drosophila Optic Lobe
928-Neural Circuits and the Encoding of Temporal Statistics
927-Human Blood-Brain Barrier Spatiotemporal Development
926-CellFluxRL: Virtual Cell Modeling
925-Mitochondrial Metabolism Fuels Anti-cancer cDCs
924-Cycling Treg & cDC2 for Breast Cancer Immune Escape
923-A Tumor-Driven Collapse of Systemic Homeostasis
922-Context-Aware Precision Oncology
921-Early Malignant Transition of Hepatocellular Carcinoma
920-Nociceptor Subsets Regulate Skin Inflammation and Itch
919-SMG1 Inhibition and Expansion of Cancer Immunopeptidome
918-Winner-Take-All Network Dynamics
917-Glial Circuit Governs Balanced Brain Injury Responses
916-Astrocyte Cell Volume Dynamics Across Cortical States
915-Sleep Interpreter: for Real-Time Memory Decoding
914-Bidirectional Brain-Fat Body Axis for Pathogen Avoidance
913-Brainstem Circuits Driving Opioid Placebo Analgesia
912-Infant Memory Schemas
911-B Cells Regulate Exercise Capacity
910-The MIND Framework for Targeted Microbiome Alteration
909-Progenitor Niche in Benign-to-Malignant Transition
908-Gene Switch for Precise Spatiotemporal Control
907-Spatiotemporal of Postnatal Brain Vascularization
906-Dual-Engram Control of Alcohol Relapse in dMSNs
905-The Core Neural Signature of Psychedelic Drug Action
904-Prefrontal TMS Therapy for Depression
903-Spatial Atlas of Healthy Human Liver from Live Donors
902-The Neural Circuitry of Maternal Aggression
901-Oncofetal Plasticity in Early Colorectal Cancer
900-Orthrus: Evolutionary Functional RNA Foundation Models
899-Cerebellar Development & Medulloblastoma Spatial
898-Remodeling of Neuronal Membrane Periodic Skeleton
897-3D Genome Organization and Regulation in Brain
896-Spatial Map of Metastatic Breast Cancer Biopsies
895-The Neural Hub of Sickness Behavior
894-Mapping Neuronal Periodic Membrane Skeleton Interactome
893-Molecular and Spatial Signatures of Mouse Brain Aging
892-RoboChem-Flex: A Democratized Self-Driving Laboratory
891-CellAtria: Agentic AI for Single-Cell RNA-seq Analysis
890-Mitochondrial Morphology and Positioning in Connectome
889-MitoCatch: Mitochondrial Transplantation therapy
888-Proteome of Brain Vasculature across the Lifespan
887-Spatial Atlas of the Healthy Human Liver
886-PerturbFate: Mapping Melanoma Drug Resistance Regulation
885-Neural Mechanisms of Maternal Aggression Plasticity
884-Two Neurons Drive Brainwide Blood Volume Changes
883-Oncofetal Plasticity in Early Colorectal Cancer
882-Map of Human Hematopoietic Stem Cell Differentiation
881-FrontierScience: Benchmarking Expert AI in Science
880-Survey of Pathway Analysis Approaches
879-How Metastatic Tumors Hijack Hematopoietic Macrophages
878-DeSCOPE: for Genetic Perturbations
877-Neuronal Tuning Manifolds Across the Visual Hierarchy
876-NeMO: Compendium for Neocortical Development Exploration
875-Midbrain Dopaminergic Neuron Development
874-Neuroanatomical and Behavioral Mapping of Alzheimer
873-Multimodal Mapping of Neocortical Lineage Specification
872-Spatiotemporal Atlas of Human Maternal-Fetal Interface
871-scFOCAL: Drug Sensitivity Across tumor Cell States
870-Personalized Brain Decoding of Spontaneous Chronic Pain
869-The Human-Centric Evolution of Drug Discovery NAMs
868-pH-Dependent Condensates Calibrate Inflammatory Response
867-Keplerizing the Cell
866-Coralysis: Multi-Level Integration
865-Protenix-v2: Biomolecular Structure Prediction
864-CompBioBench: Agentic Systems in Computational Biology
863-The Human Developmental Cell Atlas
862-Spatial VDJ: Mapping Lymphocyte Clonal Dynamics
861-ROCKET: Experimental Structure Determination
860-Quantifying Uncertainty in Protein Sequence Embeddings
859-Integrated Analysis of Noncoding CRISPRi Screens
858-Engineered Dendritic Cells for Cardiac Remodelling
857-Decoding ReNU Syndrome
856-CARE: for Whole Slide Image Analysis
855-Human Development Multiomic Atlas
854-The Human Neural Organoid Cell Atlas
853-Architectural Secrets of the Mouse Cytoplasmic Lattice
852-Overcoming T Cell Tolerance
851-Human Endoderm-Derived Organoid Cell Atlas
850-Sparcl1 I Mitigates Abdominal Aortic Aneurysm
849-Neuroimmunometabolic in Tumor Micro- & Macroenvironments
848-GASTON: Mapping Tissue Topography
847-Epigenomic Profiling of Human Central Nervous System
846-scHiCAR: Trimodal Profiling of Gene Regulatory Landscape
845- Engineered Autologous Esophageal Conduits
844-Spatial ATAC: Epigenomic Profiling in Tissue Sections
843-Fatigue-Resistant Myoneural Actuators
842-The Architecture of Intracellular Bacteriophage Assembly
841-The Extreme Environment Microbiome Catalog
840-MYC-USP10-SOX4 Axis in Thymocyte Development
839-Perinatal Pig Brain Multi-Omics
838-Isoform-Resolved Transcriptomic of Human Placenta
837-Immune-Deficient Bacterial Gateways to Genetic Evolution
836-Genetic Architecture of an Allosteric Hormone Receptor
835-Eco-evolutionary of cross-ecosystem colonization
834-BioSeq2Seq to analyze transcriptional regulation
833-Blood Extracellular MicroRNAs Modulate Social Behavior
832-Corticostriatal Neurons in Monkeys
831-Spatial Tumor Evolution Panorama of Ovarian Cancer
830-Spatial Atlas of Small Cell Lung Cancer Metastasis
829-SMART: Spatial Multi-omic Aggregation
828-PocketXMol: Unified modeling of 3D molecular generation
827-GYDE: AI Platform for Protein Design and Engineering
826-Fibroblast NF-κB Activation Drives Lung Inflammaging
825-3D Morphogenetic Blueprint of Breast Cancer Metastasis
824-SPTEdU-seq: Spatiotemporal Newborn Cell Tracking
823-Hydrogen improves Osteoarthritic Cartilage Repair
822-Pathological Barriers to In Vivo Cardiac Reprogramming
821-Preventing Transgene Silencing During Differentiation
820-Tuft Cell Paracrine Drives Gut–Brain Parasite Defense
819-Epigenetic Memory of Colitis Promotes Tumour Growth
818-Neuron GLR-9 Receptor Regulates Salt Stress Resistance
817-AhR: Brake on Stress Adaptation and Axon Regeneration
816-Spino-Brain-Spinal Cord Loop of Chronic Mechanical Pain
815-Epigenomic Hijack Developmental Lineages in Ependymoma
814-Cancer Immunity and the Origins of NMDAR Autoimmunity
813-Functional Hierarchy of Neocortex Across the Lifespan
812-Androgen Activity and Male Bias in PFA Ependymoma
811-ATF4 Regulates DNA Repair in CUX2 Neuron Expansion
810-DNA Damage and CUX2 Neuron Loss in Neuroinflammation
809-CHARM: 4-Omics of Mammalian Gene Regulatory Landscape
808-Single-Cell Spatial Atlas of Human Skin Anatomy
807-Multitissue Epigenomic Variation of Human Disease
806-Converting Tregs into Type 1 Tumor Effectors
805-Microglia-Glioblastoma Crosstalk Mediating Invasion
804-Fates and Trajectories of Human Memory CD4+T Cells
803-Determinants of B Cell Phenotype and Antibody Breadth
802-Memory T Cell Aging and Rejuvenation
801-Landscape of Structural Variation in Pediatric Cancer
800-High-Fat Diet and Lipotoxic Mitochondrial Stress
799-ICRAFT: for Dual-Action Cancer Targets
798-CREsted: Designing Cell-Type-Specific Enhancers
797-Quantifying Uncertainty in Protein Representations
796-DIAMOND DeepClust for Protein Clustering
795-LazySlide: for Whole-Slide Image Analysis
794-LongcallR: SNP Calling of Long-read RNA-seq
793-Hypoxia-TAM Dynamics in Glioblastoma
792-Spatiotemporal Modeling of Molecular Holograms
791-Targeting uPAR-Positive Tumor with CAR T Cell Therapy
790-Whole-Body Cellular Mapping of Laboratory Mouse
789-Hyperinnervation Inhibits Regeneration in Mammalian Skin
788-The MSK-50K Pan-Cancer Resource of Driver Alterations
787-Radiotherapy Synergizes with Inducible AAV
786-Genetic Drivers of Hepatocellular Carcinoma Initiation
785-Myofibroblast Barriers to TLS Formation in PDAC
784-Spatially Anatomical Niches of Human Glioblastoma
783-Active Learning for Transcriptomic Drug Discovery
782-So3D: A Comprehensive Resource for 3D Spatial Omics
781-Functional Dissection of Human Complex Trait Variants
780-The AI Scientist
779-Microbio-Nicotinic Acid Regulate Colon Regional Identity
778-CellHermes: for Multimodal Omics Integration
777-Precision Health in Diverse UCLA ATLAS Biobank
776-A Deep RNA Sequencing Atlas of Human Sensory Neurons
775-Rewiring STAT Signaling with Trikine Immunotherapeutics
774-DNA Repair in R2 Retrotransposon Transgene Insertion
773-Cytoskeletal Instability of Cytoplasmic Partitioning
772-3d-OT: Geometry-Aware Framework for Spatial Alignment
771-A Pan-Cancer Atlas of Double-Negative T Cells
770-Genes2Genes: for Single-Cell Trajectory Alignment
769-Benchmarking Tumor Subclonal Reconstruction Algorithms
768-OmicClaw: Language Framework for Multi-Omics Analysis
767-Defining a Cancer Dependency Map
766-Functional Mapping Mammalian Whole Brain via Perturb-seq
765-Celcomen: Spatial Causal Perturbation Modeling
764-X-Cell: Scaling Causal Perturbation Prediction
763-Maf and Jun Regulate Zeb2 to Drive Microglia Development
762-Regulatory Networks Governing Human Cortical Cell Fate
761-Spatial Tumor Evolution Panorama of Ovarian Cancer
760-Mapping Gene Cascades from Regulators to Traits
759-Logic-Gated Engagers Enhance Macrophage Killing
758-DNA Synthesis via Manufacturing-Aware Generative AI
757-scHiCAR: Trimodal Single-Cell Profiling
756-Microalgal Factories for Molecular Crystals Biosynthesis
755-PlasMAAG: Reconstructing Plasmids Using AI
754-Ovrlpy: Identifying 3D Signal Overlaps in Spatial Data
753-Customizing CRISPR PAM Specificity with Language Models
752-Engineered Living Glues for Inflammatory Bowel Disease
751-SPLISOSM: Mapping Spatial Isoform Patterns
750-CONCORD for Single-Cell Representation Learning
749-DECODE: A Universal Multiomics Deconvolution Framework
748-Pandemic-Scale Phylogenetics: Modeling Mutation Rates
747-Benchmarking Xenium In Situ Data Analysis Workflows
746-INSTALL: Immune Evasive Kilobase Scale Genome Writing
745-Ageing Promotes Lung Cancer Metastasis
744-PerturbDiff: for Single-Cell Perturbation Modeling
743-Mechanotransduction in the Nucleus
742-AlphaCell: for Simulating Cellular Perturbation Dynamics
741-EdgeMap: for Intercellular Communication Components
740-B Cell Imprinting in Children
739-Dynamic Basis of G-Protein Recognition and Activation
738-Multidimensional Profiling of Supratentorial Ependymomas
737-The Interoceptive of Age-Associated Cognitive Decline
736-Predicting Insulin Resistance Using Wearables
735-Phage–Pathogen Coevolution by Clinical Surveillance
734-The Tumor Microbiota
733-Tumor-restraining Fibroblasts Emerge to Chemotherapy
732-A Closed Tumor-Immune-Brain Circuit in Cancer Cachexia
731-SLC25A35: for Glycerolipid Synthesis
730-GPS: Deep Learning for De Novo Drug Discovery
729-An Epigenetic Atlas of the Aging Mouse Brain
728-The Evolution of Human Cerebellar Synaptogenesis
727-4D Simulations of the Genetically Minimal Cell Cycle
726-ChatSpatial: Agentic for Spatial Transcriptomics
725-Viral Evolution Preceding Zoonotic Outbreaks
724-Ferritin Aggregation Cell Engagers for CAR T Avidity
723-BHB Enhances CAR T Cell Antitumor Function
722-Immune-Microbiome Coordination in Healthy Humans
721-Optovolution: Directed Evolution of Multi-State Proteins
720-ROCK2 Inhibition for Treatment of Liver Fibrosis
719-OXGR1: A Therapeutic Switch for Rosacea Erythema
718-SelO Regulates Mitochondrial Homeostasis
717-Sildenafil as a Repurposable Therapy for Leigh Syndrome
716-stVCR: Spatiotemporal Single-Cell Dynamics
715-Connectome-seq: Neuron Mapping at Single-Synapse
714-CellVoyager: Autonomous AI Agent for ScRNA-seq Analysis
713-Parkinson’s Disease as a Somato-Cognitive Disorder
712-The Gut Microbiome and Cognitive Decline in Ageing Mice
711-Atlas-Guided Genetic Switches for T Cell Programming
710-Engineering Lipid Nanoparticles for Drug Delivery
709-Repression of a Cell-Cycle Protein Hinders Malaria
708-Fecal Exfoliome Sequencing for Noninvasive Profiling
707-Viral Evasion of Host Codon Usage
706-Biomolecular Profiling for Noninvasive Health Monitoring
705-Targeting Amyloid-β Pathology with CAR-Astrocyte Therapy
704-STING–NF-κB builds an influenza spillover barrier
703-A Negative Loop in Plant Inflorescence Indeterminacy
702-Structural Basis for mTORC2 & Akt Phosphorylation
701-Redefining Targetable CD70 Expression with HIT T Cells
700-Termination of the Integrated Stress Response
699-Organism-Wide Cellular Dynamics in Mammalian Aging
698-Learning Neural Redundancy in Macaque Visual Cortex
697-Whole-Brain Cell Atlas of Circadian Neural Activity
696-Tumor-Immune-Neural Circuit in Cancer Cachexia
695-Ecological Balance Index of Gut Microbiome Health
694-Cellular Basis for Mammalian Nocturnal-Diurnal Switch
693-Structure-Guided Discovery of Viral Sponges
692-In Vitro Reconstitution of Testicular Niche
691-FlashS: Detection for Scalable Spatial Transcriptomics
690-Thermal Limits & Genomic Signatures of Tropical Insects
689-Evo 2: A Foundation Model for All Domains of Life
688-Microbial Drivers of Colorectal Peritoneal Metastasis
687-Photoreceptor Signature in Pediatric Brain Tumors
686-TGFβ-Induced Atypical EMT and Immune Mechanosurveillance
685-Brainstem Organoid Models of DMG and GD2 CAR T Therapy
684-Microbial Signatures of Glioblastoma Metastases
683-Targeting TRBC2 for the Treatment of T Cell Cancers
682-SMARCA5 Control: Decoupling Pancreatic Malignancy
681-A Multiomic Atlas of Treatment Resistance in T-ALL
680-SMMILe: Spatial Quantification in Digital Pathology
679-TP53-Associated Spatial Atlas of Lung Adenocarcinoma
678-Developmental Cell Atlas of the Human Cerebellum
677-TabulaTIME: Pan-Cancer Landscape of Profibrotic Ecotypes
676-Single-Cell Profiling of Multiple Myeloma Tumor Cells
675-Miro2-Driven Mitochondrial Transfer
674-NF-κB Control Prostate Stem Cell Plasticity
673-Endothelial Dysfunction as a Driver of Cancer Cachexia
672-Plexin-B2-Mediated Glioblastoma Invasion Tracks
671-Neutrophil-Tumor Interactions in Breast Cancer
670-Evolution of IDH-Mutant Glioma Progression
669-Single-Cell Landscapes of Olfactory Neuroblastoma
668-Spatial Stem-Like Evasion in Residual Liver Cancer
667-A Pan-Cancer Resource of 1,294 Plasma cfDNA Methylomes
666-Epitranscriptomic Screens for m6A Sites in Cancer
665-CRTAM as a T Cell Checkpoint for Immunotherapy Toxicity
664-GENEVA: Modeling KRAS Inhibitor Responses
663-Predictors of Response to Immune therapy in TNBC
662-Hypoimmune CD19 CAR T Cells Evade Allorejection
661-Pancreatic Cancer Organoid Biobank
660-Stem Cell Engineering of A10 Dopamine Neurons
659-Reconstructing Endocrine-Complete Stem Cell Islets
658-Calcium Imaging in CA1 Dendrites
657-Neural Manifolds and the Structure of Recurrent Networks
656-Cellular Architecture in the Spinal Cord
655-Spatial Atlas of the Human Suprachiasmatic Nucleus
654-mFISH3D: AI-Driven Whole-Organ Spatial Mapping
653-Converging Dopamine Encode Exploration Decisions
652-Postsynaptic AMPAR Regulate Short-Term Plasticity
651-S100A8/A9 and Hypothalamic Regulation of Cancer Cachexia
650-Vascular STING Activation for NK Cell Immunity in SCLC
649-SPYTAC: Peptide Platform for Amyloid-β Degradation
648-FAScore: Model for Functional Alternative Splicing
647-Monod: Biophysical Modeling of Transcriptional Dynamics
646-Steering and Monitoring AI Models
645-Spatiotemporal Progenitor Zones in the Human Cerebellum
644-Cerebellar Tumour Origins in Fetal Programs
643-EMT and Cancer Stem Cells
642-Tumor Cell Differentiation in Medulloblastoma
641-A Brain–Gut Circuit Hijacked by Colorectal Cancer cells
640-Stalled Differentiation of Human Rhombic Lip in MB
639-Rhombic Lip Origins of Group 3 and 4 Medulloblastoma
638-The Evolution of Stem Cell Models in Medulloblastoma
637-Epigenetic Reprogramming of Medulloblastoma Metastasis
636-Evolution and Development of the Mammalian Cerebellum
635-The Medulloblastoma Metastatic Niche
634-The GPX1-OSBPL8 Axis: Pathway for In Vivo Ferroptosis
633-Resolving Medulloblastoma Cellular Architecture
632-Pyruvate is a natural suppressor of interferon signaling
631-Chemotherapy-Induced Tumor Immune Evasion
630-CAF Lipid Reprogramming Enhances T Cell Cytotoxicity
629-Architecture of Hantavirus Glycoprotein Tetramers
628-The Cellular Orchestra of CAR T Success in Myeloma
627-Macrophages: Next-Generation Cancer Immunotherapy
626-Advancing Cellular Immunotherapies for Solid Tumors
625-The CUBIC Organ and Body Atlas
624-MicrobeAtlas: Database of Earth's Microbial Ecosystems
623-HoloTea: 3D Flow Matching for Volumetric Transcriptomics
622-Functional Connectivity Gradients Across the Human Brain
621-Tracking Innate Immune Activation in Multiple Sclerosis
620-Multimodal MRI Atlas of the Human Cerebellum
619-Landscape of Human Fetal Cerebellar Development
618-Single-Cell Nuclear Compartments in Mouse Cerebellum
617-The Origins of Medulloblastoma
616-Gradients of Structural Human Cerebellar Development
615-Functional Mapping of the Human Cerebellum
614-Development of the Human Cerebellum from Birth to Five
613-Functional connectivity of the cerebellum
612-A Spatial Atlas of the Mouse Brain Complement System
611-Methodological Limitations in Lesion Network Mapping
610-Spatial Tri-omics Mapping of Brain Development
609-Dendritic Microenvironments for Mouse Brain Parcellation
608-HoloBrain and HoloGraph: Oscillatory Synchronization
607-Multiscale Morphometry of the Whole Mouse Brain Database
606-Determinants of Tissue-Specific KRAS Cancer Evolution
605-D-LMBmap: Automated Pipeline for Whole-Brain Mapping
604-Dynamic Dural Sinuses: Gatekeepers of Meningeal Immunity
603-Causal Regulatory Variants in Human Disease
602-Whole-Brain Connectivity Predicts Psychosis Risk
601-Stimulation mapping and whole-brain modeling
600-The Human Brain Metabolic Connectome
599-Foxf2 Maintains Brain Endothelial Function
598-Brain Propagations from Childhood to Adulthood
597-CATS Net: Modeling Human Concept Formation
596-Whole-brain Annotation of Drosophila
595-Celluar Atlas of the Entire Mouse Brain
594-Neural Transformations of the Second Pregnancy
593-VCWorld: A Biological World Model for Virtual Cells
592-LUMI-lab:AI-Guided Discovery Platform
591-The Skull Bone Marrow and Brain Tumor
590-PHNToM: Inference of Oncogene Mutation Function
589-Environment Shape the Human Immune Cell Epigenome
588-Human Retina Cell Atlas
587-The Cellular Landscape and Heterogeneity of COPD
586-IgG1 Plasma Cell Responses to Immune Checkpoint Blockade
585-Drivers of Gastric Cancer Response to Immunochemotherapy
584-GPLD1 and TNAP Regulation of Cognitive Function in Aging
583-Y Chromosome Variation and Type 2 Diabetes Regulation
582-The Hallmarks of Cancer
581-Histidine Scanning for Engineering TCR Sensitivity
580-Planetary Microbiome and Generalist-Driven Gene Flow
579-Oncolytic Virus Triggers Persistent T Cell Immunity
578-A Single-Cell Atlas of Embryonic Endothelial Development
577-PocketXMol: Unified modeling of 3D molecular generation
576-Global Genomic Atlas of Infant Bifidobacterium infantis
575-Brain-Wide Atlas of Oligodendrocyte and Myelin Dynamics
574-OmicVerse: Bridging Bulk and Single-Cell Transcriptomics
573-PIVOT for Multi-omic Spatial Data Integration
572-The Tumor-Immune-Neural Circuit Driving Cancer Cachexia
571-PaperBanana: Automating Academic Illustration
570-BayesPrism: Cell Type and Gene Expression Deconvolution
569-SpaceTracer: High-Resolution Spatial Lineage Tracing
568-Seq-Scope-X: Submicrometer Spatial Multi-omics
567-HistoSweep for Digital Pathology and Omics
566-The Landscape of HumanTuberculosis Granulomas
565-Planetary Microbiome Structure and Global Gene Flow
564-Sensory Neurons Drive Immune Exclusion in Breast Cancer
563-Intracellular Bacteria Promote Breast Cancer Metastasis
562-Meningeal Vessel Blockage Enhances Anti-GBM Immunity
561-Evolutionary of Mammalian Rete Ridge Formation
560-Parkinson’s disease as a somato-cognitive disorder
559-Tumour–Brain Crosstalk Restrains Cancer Immunity
558-ATF6α: A Driver of Liver Cancer
557-Decoupling T Cell Exhaustion from Protective Memory
556-Scissor: Linking Bulk Phenotypes to Single-Cell
555-SpaLP: Ultrafast for Large-Scale Spatial Omics Analysis
554-SpatialAgent: Autonomous AI Discovery in Spatial Biology
553-PRISM: Precise Microbial Identification in Human
552-Armored Anti-TREM2 CAR T Cells for Solid Tumor
551-IGSF11-VISTA: A Targetable Immune Axis
550-CAR-T Reprogram Macrophage Tumor Microenvironment
549-IFNγ-Metabolic Control of Lymphatic Metastasis
548-CCL3-Expressing Aged Neutrophils Drive Tumor Progression
547-HIC1 defines Mesenchymal Progenitor Quiescence
546-Male-Biased Yap1-CD276 Axis in Medulloblastoma
545-AI for Cancer Treatment: Navigating the Chain of Trust
544-Spatial Metastatic Tolerance in Lymph Node Niches
543-The Landscape of KRAS Inhibitors in Cancer Treatment
542-To Minimize Skin Fibrosis and Scarring
541-Cancer-Derived Cystatin-C Attenuates Alzheimer’s Disease
540-POCKET: Conformal Bioelectronics for Whole-Organ Therapy
539-CRISPR Screens Reveal Neuronal Tau Proteostasis
538-Sympathetic Nerve Regulation of Memory T Cell Immunity
537-Neural Pathways of Cardiac Remodeling
536-Atazanavir Mediates Sustained GPCR Signaling
535-Neural Dynamics in compulsive behavioral
534-An mobile peptide sparks systemic stomatal immunity
533-SLC45A1 Loss and the Neural Lysosomal Proteome Landscape
532-Urine Liquid Biopsy for Bladder Cancer Monitoring
531-Tau's Chemical Fingerprints Distinguish Dementias
530-SpatialToolDB: A Global Guide to ST Analysis
529-Spatial Mapping in the Embryonic Brain
528-Human-scATAC-Corpus
527-CMAP: Spatial Mapping of Single-Cell Transcriptomes
526-HistoCell: Cell Spatial Profiling from Histology Images
525-River: Prioritizing Differential Spatial Gene Patterns
524-PAF15 Regulation of DNA Replication Dynamics
523-Rhesus Macaque and Human Placental Organoids
522-African Plasma Proteomics in Type 2 Diabetes
521-The unique architecture of umbrella toxins
520-MultiCell: Geometric Learning in cellular Development
519-A Single-Cell Map of the Pan-Tumour Vascular Landscape
518-Gaia: Context-Aware AI for Protein Sequence Annotation
517-NLRP3 inflammasome hyperactivation in obesity
516-Macrophage MR1 antigen presentation promotes immunity
515-Human MGE Development and Inhibitory Neurogenesis
514-CaMVIA-3D for 3D Volumetric Analysis of Cardiomyocyte
513-Beige Fat Identity of Blood Pressure
512-Blood vessels under pressure
511-Evolutionary Origins of Human Brain Complexity
510-Spatial Map of Esophageal Carcinogenesis
509-Gene Expression Noise in Development
508-Multi-omic Regulation in the Aging Kidney
507-TEDD 2.0: Database for Temporal Gene Expression Dynamics
506-scRank: Inferring Drug-Responsive Cell Types
505-Bispecific Peptide-Nanozyme Conjugates for Immunotherapy
504-Pan-cancer Spatial Atlas
503-FOCUS: Mastering Research with AI-Assisted Workflows
502-Benchmarking Single-Cell Perturbation Response Models
501-DrugCLIP: Virtual Screening via Contrastive Learning
500-AlphaGenome
499-Redox and Ferroptosis Resistance in Airway Inflammation
498-Enhancer Landscapes of Microglial Plasticity
497-hPSC-Derived Immune Cells for Cancer Immunotherapy
496-Vascularized Human Retinal Organoids
495-Vitamin B6 Enhances Antitumor Immunity
494-Cell Atlas of Human Gonadal Lineage Specification
493-Commensal TMCM Lipids Protect the Ocular Surface
492-ECS-dependent polytubey block in Arabidopsis
491-Enhanced Stem Cell Differentiation
490-Peroxisome-Mediated Intestinal Repair in Long COVID
489-MYRF: Regulator of Lung Mesothelium Fate and Plasticity
488-Neddylation: Link Between Neuronal Aging and Alzheimer's
487-Peripheral Glia Orchestrate Early Immune Responses
486-3D Nichoids Enhance Gene Therapy
485-Clinical Translation of Fertilo for In Vitro Maturation
484-Metabolic Restoration of Stem Cell Fitness
483-Screening Organoids for Pancreas Acinar Specification
482-Mapping Brain Connectivity Changes
481-Microbiota-Driven TH17 Trans-differentiation
480-DeepMet: Language Models for Human Metabolite Discovery
479-Genetic Architecture of Aortic Valve Function
478-popEVE: A Proteome-Wide Model for Human Disease Genetics
477-Spatial Multi-omics Atlas of Human Liver Disease
476-Hypermutation Patterns in Glioma Tumorigenesis
475-DNA-Diffusion:Design Cell-Specific Regulatory Elements
474-p53 Inactivation in Breast Cancer Metastasis
473-Correcting Segmentation Errors in Spatial omics
472-Clinical Genetic Variation in the Mexican Biobank
471-MedHELM: for Real-World Medical Tasks
470-Integrated Multimodal Spatial Omics Mapping via DBiTplus
469-MYC-Driven Lipid Dependency in Medulloblastoma
468-ADAPT: Real-Time Tumor Evolution Analysis
467-Proteogenomic Landscape of Gallbladder Cancer
466-Axes of Biological Variation in DLBC Lymphoma
465-ASCEND-CRC: Intercepting Cancer Evolution
464-ADAM12: A new Checkpoint impeding Anti-Tumor Immunity
463-Spatial Predictors of Immunotherapy Response
462-Architecture dynamics of vesicle tethering in exocytosis
461-SupTAC: for Spatiotemporally Protein Degradation
460-Hijacking Calvarial Immune Cells for Stroke Therapy
459-Discovery of CARD9 Inhibitors for Anti-Inflammatory
458-Olfr110 Signaling and Hepatic Glucose Homeostasis
457-Myelin-Reactive B Cells to Drive Demyelination
456-EBV Cross-Reactivity of Multiple Sclerosis
455-EBV and HLA-DR15 Synergism in Sclerosis Pathogenesis
454-Scouter: Predicting Gene Perturbation Outcomes
453-Fatty Acid Recognition by Olfactory Receptors
452-Distinct of glia in the enteric nervous system
451-Landscapes of Viral Encephalitis and Synaptopathy
450-VCP Drive Pathogenic Nuclear Pore Complex Degradation
449-TMEM63A regulates myelin sheath geometry
448-Prying Off The Brain's Molecular Bouncer
447-Neural Rhythms and Breast Cancer
446-Killing superbugs with lemons and ghost bacteria
445-The Human Skin Microbiome: Metagenomes to Therapeutics
444-The Mouth Bacterium Fueling Colorectal Cancer
443-The Gut Microbiome and Social Behaviour
442-Ancient Pathogen Genomics
441-The Gut Microbiome for Transplantation Success
440-Harnessing the Microbiome for Cancer Therapy
439-The Oral–Gut Microbiome Axis in Health and Disease
438-Global Microbial Signatures of Health and Disease
437-HELIOS: Precision Medicine for Asian Populations
436-Acute Exercise and the Human Immune Cell Proteome
435-To tackle antimicrobial resistance
434-Stress-Trained Microalgae Robots
433-Closed-Loop Wearable Neurostimulation System
432-Multisynaptic Spiking Neurons
431-CellRank: Directed Single-Cell Fate Mapping
430-Cas12a3 cleaves tRNA tails to execute bacterial immunity
429-Securin-Independent Regulation of Separase by SGO2
428-Cellular Dynamics in Developing Mouse Brains
427-TFAP2β Condensation Suppresses ESCC Progression
426-Dendritic Cells Orchestrate Innate-Adaptive Trade-offs
425-Extracellular GPX4 impairs antitumor immunity
424-3D In Vitro Model for Human Implantation
423-CyCLoPs: Monitoring In Vivo Cytokine Activity
422-Profile Neural Organoid Response to Morphogens
421-Apoptotic Cell Identity Shapes Macrophage
420-Stack: A Context-Aware Model for Single-Cell Analysis
419-ClockBase Agent: AI Discovery of Aging Interventions
418-CIMA: A Multi-Omics Atlas of the Chinese Immune System
417-Pan-Cancer Single-Cell Atlas
416-ChatNT: A Conversational Agent for DNA, RNA and Proteins
415-Modeling Human Embryo Implantation In Vitro
414-IGLL5+ B Cells Disrupt TLS Homeostasis and Response
413-DNA Degradation by Ubiquitination Regulates cGAS–STING
412-CLINK: Bioprinting of Ultrahigh Density Tissues
411-Treg Therapy: The Dawn of Precision Immune Tolerance
410-Mitochondrial Transfer from Glia to Neurons
409-A mechanical ratchet drives unilateral cytokinesis
408-An expanded registry of cis-regulatory elements
407-SpaceBar: Clone Tracing via Spatial Transcriptomics
406-Targeting and Tracking mRNA Lipid Nanoparticles
405-UNAGI: AI for Disease Progression and Drug Discovery
404-MISO for Integrated Protein Purification and Cryo-EM
403-EcDNA Variants Drive Oncogenic Transcript Amplification
402-Logic of Localized Mitochondrial Translation
401-Epigenetic Plasticity in Germinal Centre B Cells
400-A clinical road map for single-cell omics
399-SPLISOSM: Mapping Spatial Isoform Diversity in Brain
398-AI Virtual Spatial Proteomics from Histopathology
397-Spatial Mapping of Human and Mouse Pulmonary Fibrosis
396-scPEFT: Fine-Tuning for Single-Cell Foundation Models
395-ImmunoStruct: Multimodal for Immunogenicity Prediction
394-MetaAI: Physics-Aware for Metasurface Discovery
393-GITIII: Inferring Single-Cell Interactions
392-scDiffEq: Learning Cell Dynamics
391-Modeling Brain Dysconnectivity in Rodents
390-CellOT: Learning Single-Cell Perturbation Responses
389-TransBrain: Mapping Whole-Brain Between Humans and Mice
388-cellSTAAR: Boosting Rare Variant Association Testing
387-Pertpy: Framework for Single-Cell Perturbation Analysis
386-SpatialZ: Reconstructing 3D Cell Atlases
385-IRIS: Reference-Informed Segmentation for Spatial data
384-FX-Cell: ScRNA Sequencing for Challenging Plant Samples
383-FlashDeconv: Atlas-Scale Spatial Deconvolution
382-3D Spatial in Thick Tissue Blocks
381-Multiplexed ultrasound imaging of gene expression
380-HR-IMC: Submicrometer Resolution Imaging Mass Cytometry
379-Spotiphy: Single-Cell Spatial Across Entire Sections
378-Light-induced extracellular vesicle/particle adsorption
377-Jaxley: Simulation for Biophysical Neural Models
376-Novae: A Foundation Model for Spatial Data
375-Bin Chicken: for Novel Genome Recovery
374-STAIR: 3D Reconstruction and Integration of ST Data
373-MetroSCREEN: Mapping Pan-Cancer Metabolic Subtypes
372-Roadmap for Modelling Brain Development with Organoids
371-TNBC Response Trajectories
370-Metabolic Stress Priming in Hepatocarcinogenesis
369-An Integrated Atlas of the Human Vascular System
368-scTenifoldKnk: Virtual Gene Knockouts
367-Mutations in FDX2 Suppress Frataxin Deficiency
366-CellSAM: A Foundation Model for Cell Segmentation
365-MisTIC: Correcting Transcript Misassignment in ST Data
364-RADIANT: Highly Multiplexed Volumetric Mapping
363-PASTA: Accurate PAthway-oriented Spatial gene imputation
362-FastGlioma: AI for Rapid Tumor Infiltration Detection
361-Combocat: for Discovery of Synergistic Drug Combinations
360-GigaTIME: AI for Virtual Tumor Microenvironment
359-PLATO: High-Resolution Spatial Proteomics
358-CNS Tumor Classification by DNA Methylation Profiling
357-SOX2-Driven Niche Sculpts Neutrophil Immunosuppression
356-The LINUXtrial: AI Enhances Precision Treatment
355-Paneth-like Transition Drives Cancer Resistance
354-Medulloblastoma Stem Cell Programs and Progression
353-IL-36γ Armored CAR T Cells Reprogram Neutrophils
352-Multi-omic Landscape of Human Gliomas
351-RHOA Regulates Mitochondria-ER Contact Sites
350-PhenoProfiler: Image-Based Drug Discovery Learning
349-Spatial organization of mitochondria in neurons
348-mTORC2 Recognizes AGC Kinases by Long-Range Docking
347-Plasmid Population Dynamics
346-Microbial Signals in Primary and Metastatic Brain Tumors
345-Histamine Signaling Gates Fat Preference in the PVT
344-ApoE Variants Protect Neurons by Oxidized Lipid Efflux
343-Sympathetic functional units encoding
342-Brain Fluid Dynamics
341-Cystine and GPX4 Drive ILC2 Pathogenicity
340-Hepcidin-Iron Axis Impairs Antiviral Immunity
339-Persistent Tfh Cells Drive HIV Vaccine Responses
338-NFATc1 Constrains Bystander Activation of CD8+ T Cells
337-Rod-shaped microglia in Neurodegeneration
336-Eukaryote Assembly Timeline from Dated Gene Duplications
335-TSC tunes Cortical Progenitor Balance and Neurogenesis
334-Modelling late gastrulation in monkey embryo models
333-Genomic Landscape of Breast Cancer Subtypes
332-Cell State Plasticity Drives Olaparib Resistance
331-Architecture of the Neutrophil Compartment
330-COAST: Image-Guided Multi-Modal Spatial Tissue Alignment
329-StaVia: Temporal Spatially Aware Cell Atlas Cartography
328-A Whole-Brain Circadian Atlas of Neural Activity
327-Paneth Plasticity in KRAS Colorectal Cancer
326-mTOR Regulation of Cytoskeleton Drives Mitoxyperilysis
325-Structural Basis of Toxin Targeting by UmbA Lectins
324-Sympathetic Stress Links Hair Loss to Autoimmunity
323-Gq-Biased CCKBR Agonism for Alzheimer's Therapy
322-Sensing of Mechanical Stress Governs Tissue Growth
321-Hepatic Zonation Dictates Cancer Initiation
320-Validated Single-Neuron Connectome of the Mouse Brain
319-Spacedust: Discovery of Conserved Gene Clusters
318-Whole-brain reconstruction of fiber tracts
317-X-ray Nanotomography of Intact Neural Tissue
316-TIRTL-seq: Deep Paired TCR Repertoire Sequencing
315-Unified Benchmark of TCR–Epitope Prediction Models
314-DeepCor: Contrastive Autoencoders for fMRI Denoising
313-Whole Genome Doubling Remodels Ovarian Cancer Evolution
312-Hypoxia Shifts Melanoma Ferroptosis Reliance to FSP1
311-Multitask Evaluation of Single-Cell Integration Methods
310-PD-1 Sustains High-Affinity T Stem Cells
309-Amazonia's Wild Meat: Nutritional Lifeline and Decline
308-Neural Coding of Universal Phonetics and Word Structure
307-Spatial fibroblast niches define Crohn’s fistulae
306-NSD2 targeting reverses plasticity in prostate cancer
305-Topographic Body Maps Tiling Human Visual Cortex
304-Neuronal Glutamate Signaling Hijacks Pancreatic Cancer
303-TITAN: Multimodal Whole-Slide Pathology Foundation Model
302-Senescence: Double-Edged Sword in Precancer Interception
301-apCAF Spatial Niches Define SPP1-Driven Tumor Virulence
300-Selection Gene Drives Combat Tumor Drug Resistance
299-Limitations and Augmentation of Cell Embedding Metrics
298-scPRS: Risk Scores Dissect Complex Disease Heterogeneity
297-cSplotch: Inferring Cell-Type-Specific Spatial profile
296-PRISM: Single-Round High-Multiplex Spatial RNA Imaging
295-BRAIN-MAGNET Atlas of Non-Coding Regulatory Elements
294-Systema: Evaluating Genetic Perturbation Prediction
293-3D Deep-STARmap and Deep-RIBOmap in Thick Tissues
292-PERT for Disease-Agnostic Nonsense Mutation Readthrough
291-Prognostic ctDNA Monitoring in Resectable NSCLC
290-Perturb-Seq: Single-Cell Profiling of Genetic Screens
289-The TIG1 Primes Cells for SARS-CoV-2 Infection
288-Motor Cortex Connectivity and Goal-Directed Reaching
287-scArches: Reference Mapping for Single-Cell Atlases
286-Myeloid-Targeted Immunocytokines
285-Convergence in Human Neuroscience
284-The Human Cell Atlas: From Census to Foundation Model
283-Translational Control of Cellular Stress and Aging
282-CellNavi: Predicts Cellular Transition Driver Genes
281-Perturb-seq Maps Genotype-Phenotype Landscapes
280-SpatialZoomer: Multi-Scale Spatial Transcriptomics
279-X-Atlas/Orion: Genome-Scale Causal Biology
278-Immune Architecture in the Second-Trimester Fetus
277-Squidiff: Predicting Cellular Responses
276-Compressed Perturb-seq for Genetic Screens
275-Developmental Trajectories of Mouse Visual Cortex
274-AGE-Induced Viscoelasticity Drives HCC via TNS1
273-u-Segment3D: Universal 2D-to-3D Cell Segmentation
272-OTX2 Governs Human Early Embryonic Genome Activation
271-ELLA: Subcellular Spatial Localization Analysis
270-Iron Recycling Macrophages Drive Bone Metastasis Anemia
269-MAGE: Generative AI for De Novo Antibody Design
268-PROGENy: Pathway Activity Inference from Gene Expression
267-CellWhisperer: Chat-Based Single-Cell RNA-Seq Analysis
266-SGS: Visualizing Single-Cell and Spatial Multiomics Data
265-High-Resolution Atlas of Hematopoietic Progenitors
264-snATAC-seq in the Adult Mouse Brain
263-Proinflammatory Niches Drive Lung cancer Initiation
262-Mammalian Brain Cell Atlases and Neurodevelopment
261-Spatial Atlas of Brain Development and Neuroinflammation
260-Taxonomy of Telencephalic GABAergic Neurons
259-STORIES: Spatial Trajectory Inference
258-NextBrain: Histological Atlas of the Whole Human Brain
257-Nicheformer: for Single-Cell and Spatial Omics
256-Benchmarking Spatial Transcriptomics Platforms
255-Spatial Mechano-Transcriptomics
254-Flexynesis: for Multi-Omics Data Integration
253-Rewiring of cortical glucose metabolism fuels GBM growth
252-Multiscale Integrated Cell Map of Protein Assemblies
251-CellNEST: Cell-Cell Networks in Spatial Transcriptomics
250-The Neuro-Immune Axis of Virtual Infection Threat
249-Aging Macrophages Drive Adipose Dysfunction
248-Reprogramming neuroblastoma by Diet Polyamine Depletion
247-Remodeling Cold Tumors for Immunotherapy
246-Tahoe-x1: Perturbation Single-Cell Foundation Models
245-A Neural Manifold View of the Brain
244-T-SenSERs: Design Synthetic Receptors for Enhanced CAR-T
243-AI-Driven Traditional Chinese Medicine
242-Spatiotemporal Atlas of Early Human Heart Development
241-Hypoxia Directs Human Lung Airway Differentiation
240-TLS Determine Glioma Immune Microenvironment
239-BST2 Astrocyte Drives Microglial Recruiting After Stroke
238-Vitamin C Decelerates Primate Ovarian Aging
237-A novel human heart-macrophage assembloid (hHMA)
236-SphereDiff for Parkinson's Cell Therapy
235-MrVI: AI Model for Single-Cell Heterogeneity
234-Spatial Niches in Diffuse Large B Cell Lymphoma
233-Ctyper: Genotyping CNV Using Pangenomes
232-GPR116+ Pericytes Drive Esophageal Cancer Metastasis
231-Rapid Epigenomic Classification of Acute Leukemia
230-Comprehensive genomic analysis of land plants
229-Comparing EHR and Polygenic Risk Scores
228-ERG-Driven Prostate Cancer Requires KMT2A and DOT1L
227-Engineering and Ecology of Human Gut Temperate Phages
226-Macrophage Loss Promotes Skin Capillary Ageing
225-Spatial Metabolic Gradients in Liver and Intestine
224-HippoMaps: Cartography of Human Hippocampal Organization
223-PrecisION: Native Top-Down Mass Spectrometry Software
222-InterPLM: Interpretable Protein Language Models
221-RNA-Stabilized Coat Proteins for Single mRNA Imaging
220-iSCALE: Spatial Transcriptomics for Large Tissues
219-GHIST: Spatial Gene Expression from Histology
218-Benchmarking Functional Connectivity Mapping Methods
217-HMGN1 Dosage Drives Down Syndrome Cardiac Defects
216-All-Optical In Situ Histology of Heterogeneous Tissue
215-CaCoFold-R3D for predicting RNA structure
214-META-SiM: Foundation Model for Single-Molecule Discovery
213-OrganoidTracker 2.0: Cell Tracking with Error Prediction
212-Neuroimmune Circuit Enables Cancer Immune Evasion
211-Benchmarking Multimodal Omics Integration Methods
210-CELLECT: Efficient Contrastive Cell Tracking
209-scooby: modeling multimodal profiles from DNA sequence
208-PHLOWER: Inferring Differentiation Trajectories
207-SpaceSequest: A Unified Spatial Data Analysis Pipeline
206-BioinfoMCP: Unifying Bioinformatics Tools with AI Agents
205-PhenoProfiler: Phenotypic Learning for Drug Discovery
204-How to develop good research questions
203-EpiAgent: Foundation Model for Single-Cell Epigenomics
202-sosta: Structure-Based Analysis of Spatial Omics Data
201-C2S-Scale: Scaling Single-Cell Analysis with LLM
200-The Neuroscience of Brain Cancers
199-Restraint of Cancer Plasticity by Spatial Clustering
198-T Cell Immunoediting Prevents Sarcoma Tumor Emergence
197-How Bacteria Modifies Cancer Cell Architecture
196-TET2-Mutant Hematopoiesis Enhances ICT Response
195-wellDR-seq Decodes Breast Cancer Genotype and Phenotype
194-THREADS: Foundational AI Model for Histopathology
193-IL-25 Programs ILC Memory for Mucosal Immunity
192-Creeping Fat Fibroblasts in Crohn's Stricture Fibrosis
191-Astrocyte Leaflet Domains Integrate Synaptic Signals
190-Spatial Proteomics Reveals Primary Cilia Heterogeneity
189-hESC Dopamine Progenitors for Parkinson's Disease
188-RNA Splicing Dysregulation and Cancer Hallmarks
187-Medulloblastoma Subgroups: Molecular Insights
186-Inducible Prophages in the Human Gut
185-OTX2 Regulation of Splicing in Medulloblastoma
170-CBFA Complex Mutations Drive Medulloblastoma
169-An OTX2-PAX3 signaling axis in Group 3 Medulloblastoma
168-Mapping the Plasma Metabolome to Human Health
167-Septal Macrophages Control Adipocyte Stem Cell Fate
166-Single-Cell Splicing Isoform Atlas of the Human Heart
164-Spatial Transcriptomics Dissecting Tumor-Associated TLS
165-CellPhenoX: Explainable for Single-Cell Multi-Omics
163-ROSIE: AI Multiplex Immunofluorescence from H&E Images
161-sRCC Immunobiology and Immunotherapy Prediction
162-T Cell Phenotype and Clonality in Human Tumors
160-Spatial Atlas of Developing Human Intestinal Fibroblasts
159-TopoLa: Topological Learning for ScRNA Data Analysis
158-Single-Cell Landscape of Pan-Cancer Brain Metastases
157-TPCPA: The Pan-Cancer Proteome Atlas
156-Engineering Myeloid Cells for Cancer Immunotherapy
155-AAnet Defines Triple-Negative Breast Cancer Archetypes
154-Spatial biomarkers of SHR-A1811 response
153-Cross-tissue multicellular coordination in cancer
152-IFNγ Orchestrates Leptomeningeal Anti-Tumor Response
151-Scriabin: analysis of cell–cell communication
150-Spatial transcriptomic plasticity in pancreatic cancer
149-Neuronal Communication and Alzheimer's Pathology
148-Glutamine leakage shapes root microbiota
147-Predicting the Human Protein-Protein Interactome
146-Spatial Determinants of NSCLC Immunotherapy Resistance
145-TORCH: AI Prediction of Cancer Origin from Cytology
144-ToolUniverse: Democratizing AI scientists
143-Empowering biomedical discovery with AI agents
142-Cytokines in cancer
141-CAR-T therapy in solid tumors
140-Artificial Intelligence in Drug Development
139-T Cell Exhaustion Driven by Proteostasis Stress
138-Clonal Evolution in Ovarian Cancer Drug Resistance
137-The Expanding Vistas of Spatial Transcriptomics
136-ETC Suppression Boosts Resilience to Excitotoxicity
135-PitNET Heterogeneity and Immune Remodeling
135-Proteomic Networks Drive AD's Pathogenesis
134-Giotto Suite: Spatial Multiomics Data Analysis
133-Highly Multiplexed 3D Tumor Profiling
132-OmiCLIP & Loki: Foundation Model for Spatial Analysis
131-DeepScientist: Autonomous Scientific Discovery
130-Topological Velocity Inference from ST
129-Tryptophan Metabolism Restricts TLS Maturation
128-Cancer-induced nerve injury Drives Anti-PD-1 Resistance
127-MintFlow: AI rewrite Spatial Analysis
126-Macropinocytosis Maintains CAF Subtype
125-TriPath: The 3D Pathology Revolution
124-PathoPlex: Spatial Proteomics Mapping
123-Spatial Tumor Architecture in TNBC
122-Circulating tumor cells
121-Unlock Immunotherapy Resistance by CXCR4 partial agonist
120-Stereo-seq V2: Spatial mapping with high resolution
119-Towards Robust Foundation Models for Digital Pathology
118-Interferons in health and disease
117-Mitochondrial Endosymbiosis and Inflammatory Diseases
116-Natural killer cell therapies
115-Cell Marker Accordion: interpretable single-cell
114-The integrative biology of type 2 diabetes
113-A view on drug resistance in cancer
111-p53 Suppresses Chromatin Noise and Cellular Plasticity
112-AI-Driven Super Plants: the Next Agricultural Revolution
110-Tumor neutrophils rewired from birth
109-Mechanical confinement governs plasticity in melanoma
108-Immune Dictionary at single-cell resolution
107-Glioma-Neuron Interactions: Retrograde Tracing Study
106-STAMP: Decoding Patterns in Spatial Transcriptomics
105-Nerve-to-cancer transfer of mitochondria
104-Human grammar democratize virtual cell laboratories
103-Automated Cell Classification on H&E images
102-Cellular Mapping of Attributes with Position (CMAP)
101-Computational Design of Specific DNA-Binding Proteins
100-Unlocking the Blood-Brain Barrier
099-Unpacking Neurodegeneration with Blood Proteomics
098-The Global Neurodegeneration Proteomics Consortium
097-Immature Neutrophils in Bone Metastases
096-TrimNN: Analyzing Cellular Communities
095-OpenCell: Mapping Human Cell Organization
094-DOLPHIN: Using RNA splicing to enhance ScRNA analysis
093-How to Pick a Graduate Advisor
092-How to write a high-quality scientific manuscript
091-3D nuclear segmentation for digital pathology
090-A progenitor-orchestrated niche to early tumorigenesis
089-CellFM: Human Cell Transcriptomics Foundation Model
088-Asian diversity in human immune cells
087-Cellular biogeography of human bone marrow
086-GeneAgent for gene-set analysis
085-Spatial landscape of borderline ovarian tumors
084-CellForge: Agentic Design of Virtual Cell Models
083-Tumour angiogenesis and tumour immunity
082-Single-cell spatial atlas of the human cerebral cortex
081-Cholinergic neuronal promotes diffuse midline glioma
080-Glucose restriction promotes lung pre-metastatic
079-Quantifying Gut Microbiota Fermentation Products
078-Identifying gut microbial bile acid metabolic enzymes
077-Single-cell epigenomic rewiring in Alzheimer’s disease
076-Bone metastases diminish extraosseous response to ICB
075-Fibroblast atlas
074-Reconstructing Cell Lineage Trees
073-Reshaping transplantation with AI
072-Spatially resolved cell atlas of the whole mouse brain
071-A high-resolution Mouse Brain Cell Atlas
070-High-Resolution Mouse Brain Atlas
069-Amyloids Defend Against Predatory Bacteria
068-Metabolism's 400-Million-Year Impact on Enzyme Structure
067-Genome doubling shapes evolvability & immunity in HGSOC
066-World development pathways within planetary boundaries
065-Neutrophils drive tumour necrosis and metastasis
064-Gut Infections: medication–microbiome interactions
063-How stem cells respond to infection/inflammation/ageing
062-Tumour-intrinsic resistance to ICB
061-Hallmarks of response, resistance, and toxicity to ICB
060-Chemotherapy's role in cancer treatment
059-A novel immunotherapy target AOAH
058-Diet-microbiome interactions in cancer
057-The interface of AI and translational cancer research
056-Stem cells for reprogramming and repair
055-The brain-immune code
054-Myeloid cells in the central nervous system
053-Precision Immunotherapy for Early-Stage NSCLC
052-CAR T-Cell Therapy for Pediatric Central Nervous System
051-The hidden chemicals in food
050-Insulin resistance in early-onset colorectal cancer
049-Microglial and TREM2 dialogues in the developing brain
048-Border-associated macrophages as gatekeepers of brain
047-Alzheimer’s disease and age-related macular degeneration
046-Role of specialized sensory neuron
045-Cytotoxic IgG: Mechanisms, functions, and applications
044-Long-read genome sequencing for rare diseases
043-A Guide to Extrachromosomal DNA
042-How and when organisms edit their own genomes
041-Stem cell therapies for diabetes
040-The Future of Personalized Cancer Vaccines
039-Response and Resistance to RAS Inhibition in Cancer
038-Senescence in cancer
037-Resilience and brain health in global populations
036-Neuroinflammation and microglial activation in AD
035-Multimodal generative AI for medical image
034-Distinct cellular subtypes involved in neural invasion
033-The evolution of developmental biology
032-Foundation model of causal cell
031-Spatiotemporal omics for biology and medicine
030-A developmental constraint model of cancer cell states
029-Vascular endothelium in health and disease
028-Unraveling mechanisms of human brain evolution
027-Tumor ‘‘age’’ in early-onset colorectal cancer
026-Cellular responses to RNA damage
025-The Neuroimmune Connectome in Health and Disease
024-Dietary Cycles, Gut Biome, and Cardiovascular Health
023- Why Cancer Research Needs Neuroscience
022-Cancer Hallmarks and Neurobiology
021-Reinventing type 2 immunity in cancer
020-Stress and Cancer
019-Lung inflammation drives Long Covid
018-‘Killer’ cells show promise for autoimmune disease
017-Evo 2: A Unified Genome Language Model
016-Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas
015-Arc released first Virtual Cell Model: State
014-Can AI build a virtual cell?
013-Glioblastoma Ecosystems
012-Neurons Drive Cancer Spread Via Mitochondrial Transfer
011-AI in Medicine: A House of Cards
010-Top ten tips to kick-start Scientists career
009-Y Chromosome Loss in Cancer and T Cells
008-The Spatial Atlas of Human Anatomy (SAHA)
007-Precision Geromedicine
006-The Microbiome Bridging Research and Clinical Practice
005-The Generative Era of Medical AI
004-Neuroinflammation Across Neurological Diseases
003-Perturb-Multimodal Imaging and Sequencing
002-The Neuroimmune Connectome in Health and Disease
001-Diet, Gut Bacteria, and Cardiovascular Health