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Longevity Lecture series Introduction and Lecture 1

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CABINET - trial - Cabozantinib for NET

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RFK Jr takes office/ CDC layoffs/ Varmus criticizes Jay's proposal for Academic Freedom

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Trump is breaking media brains / NIH cuts indirect payments and scientists freak out

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Elon's 6 Engineers/ Unelected/ RFK Jr/ MMR vaccines/ DEI/ USAID and NIH funding complaints

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Why the NIH is a broken funding system

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CIA says lab leak, Fauci's pardon, NIH's meetings, RFK Jr's hearing & more!

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Trump's Big Health Care Changes: NIH study sections, MMWR gag order, WHO withdrawal & more!

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The ENTIRE healthcare system is broken, not just health insurance companies

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Alcohol - Is it healthy? Everything you need to know about Beer, Wine and Spirits

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2 HOUR ASH Presentation with AARON GOODMAN & MANNI & More

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Systematic Reviews - An Introduction⧸ How to do them⧸ Search Strategies⧸ Common Errors

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Special post-ESMO 2024 edition !

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Artificial Intelligence in Medicine - My Keynote

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Masking Mistakes - my panel discussion at the Emory Center for Ethics

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How We Can Do Better As A County Hospital

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Driver mutation lung cancer - My lecture

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Post ASCO wrap up with Timothee Olivier

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Critical Appraisal - My 2 hour ASCO lecture - Day 2 version

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Asco Prequel - We talk about what to look for

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A SM crossover - Cifu, Prasad, Mandrola

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When Evidence EXPIRES - My Grand Rounds Today at Mt Sinai

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Cifu, Mandrola, Prasad - SM crossover

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Patient advocates funded by Pharma

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FDA makes MRD the basis for AA

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Beta Blockers After Heart Attacks Don't Work

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Blood based and Stool DNA colon cancer screening - Two NEJM papers

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Keynote 564 - a flawed study

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CONTACT-01 Cabo/ Atezo in Prostate Cancer - An Unethical trial

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CAR T causes MDS??? Manni, Goodman, Raj, Prasad

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Timothee and Prasad talk 2023 cancer trials

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Aaron Goodman Prasad ASH UPDATES

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Mandrola and Prasad

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COVID19 Policy: What the US Got Wrong

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Lecture 1 of 4 Curacao - How to Keep Up with Literature

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Advice Pre-Med Students | Lecture at UC Berkeley

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Radiation oncology in GI malignancy - Nina Sanford and Bill Hall

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Hawai Keynote - Coffee and colon cancer & Censoring & More

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Ethics: How IRBs Can Do Better | My Denmark Lectures (Sept 2023) 3 Of 3

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Prasad's lecture gets cancelled/ Cifu Gets COVID a SM crossover

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The State Of Immunotherapy In Oncology | My Denmark Lectures (Sept 2023) 2 Of 3

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Do We Have Good Evidence For New Drugs? My Denmark Lectures (Sept 2023) 1 Of 3

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Great And Crazy Things We Do In Medicine

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Fixing Cancer Medicine w/ Timothee Olivier

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Coumadin, ECMO, RCTs and more

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Prasad and Mandrola discuss recent journal articles/ Republicans/ Stenting

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Placebo/ Journal Errors/ Cancer Screening w/ Mandrola - SM crossover

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Testosterone/ Should Scientists Debate/ Mike Joyner

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Post Protocol Therapy - QOL - Adjuvant - Olivier Joins VP

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ADAURA OS RESULTS - THE TRIAL WAS UNETHICAL

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OBS studies vs RCTs - Trial Emulation - RCT Duplicate - We debate recent JAMA Paper

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Myeloma Roundtable - Manni M. Raj C. VP discuss controversies

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Mammographic Screening : A complete review of the evidence

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The Crushing, Cruel Cost of Cancer Drugs - My Lecture

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Sensible Med Crossover - Cifu/ Mandrola/ Prasad & Wallensky

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Cochrane Mask Debates - Jefferson/ Heneghan/ Prasad

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Zeb Jamrozik - Vaccine errors/ Sweden/ Equipoise & Science itself

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Harvard-MIT Center for Reg. Science Lecture (4-4-23) - Dubious FDA drug Approvals

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5.47 - Real World Evidence - Keynote Lecture in Denmark

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5.46 - What is Science: reflections on the field

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5.45 - Bar Karmma - Karmma 3 | Idacel vs 'standard care

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More basics on randomized controlled trials - Part 2

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RCT 101 And Papa Heme

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Tom Newman And VP Discuss Public Health

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5.41 - Michael Putman MCW debates me on recent policy Qs

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Sensible Med Superbowl Plenary Session Crossover

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5.39 - Sotorasib and Codebreak 200

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Myeloma Twitter Just Makes Things Up - Lessons for All Oncologists & Expertise

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5.37 - Keynote Lecture on Physician Burnout

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5.36 - ASH UPDATE #4 - GEM CESAR

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5.35 - ASH Update #3 - the Ascent Trial

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5.34 - ASH Update #2 - ALPINE - Zanibrutinib vs Ibrutinib - Deconstructed

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5.33 USC Grand Rounds Hematology

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5.32 - ASH Update #1 - Talquetamab NEJM

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5.31 - MUST LISTEN Grand Rounds - COVID19 Updates

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5.30 Rajkumar vs Goodman; Long COVID vs Long URI

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5.29 Smart Start is a useless Lymphoma study

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5.28 - Pandemic Amnesty or Accountability with Paul Fenyves

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5.27 - Multiple Myeloma - Do Our Trials Help Patients?

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5.26 - Hawaii Oncology Association Keynote Lecture

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5.25 - Neurosurgery Grand Rounds by Vinay Prasad

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5.24 Vlad Kogan is back to discuss Kids Test Scores

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5.24 - Gerald Hsu MD PhD UCSF Heme Onc Program Director

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5.23 - Subclinical Myocarditis

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5.23 - ID Ethicist joins me for a 6th discussion of COVID19 policy

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5.22 NordICC trial interview with PI Michael Bretthauer - Offer but don't Nudge

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5.21 Science Mag Editor Condemns Ladapo But Silent About Jha

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5.20 The Great Colonoscopy Debate

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5.19 - NEJM's first ever RCT of Colonoscopy-- Explained

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5.18 Lecture to Heme Onc Fellows - POLO; Javelin 100 bladder

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5.17 - The State Of Precision Oncology

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5.16 - Aaron Goodman UCSD

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5.15 - How To Apply For And Get Your Perfect First Job

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Unspoken Rules of Oncology - Malignant BC Part 6

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Malignant Book Club - Episode 7 - famous trials

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5.12 - Academics Vs Industry - A.Goodman S.Loghavi D.Steensma V.P.

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5.11 - Malignant Book Club - Part 5

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5.10 - Adam Cifu on clinical excellence

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5.09 - Malignant Book Club Part 4

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5.08 - LaceWing RCT Phase 3 Blood - Spin Cycle

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5.07 - Plenary Session Alps Edition

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5.06 - POLO trial now has OS results - OMG

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5.05 - Citations, Metrics, Rankings in Oncology & Medicine

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5.04 - Echelon 1 reports OS benefit - But does it add up?

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5.03 - VPs Grand Rounds Lecture - Evidence Based Medicine - Will it Survive?

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5.02 - Listener Questions - Cancer & Evidence Philosophy - What this Pod Offers

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5.01 - How To Read Randomized Trials In Cancer

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108

Lies and Exaggerations about Kids Vaccines < 5 years Old is Bad Public Health

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Enact Trial - Enza vs Active Surveillance in Localized Prostate Cancer

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Kids Vaccine For Under 5 years Old

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H. Jack West; Lung Cancer; Podcasting; TeleHealth: PACIFIC; ADAURA;CM816: KN189

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QuANTUM - Quizartinib Front Line - Ethics of Global Trials

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4.67 Teclistimab for R/R Multiple Myeloma

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4.66 PD1 Ab for MSI H Stage II/ III Rectal Cancer; A 100% CR rate??

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4.65 DESTINY BREAST 04 - A complex trial to deconstruct

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4.64 - DETERMINATION - Should we still use transplant Myeloma?

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4.63 - ASCO22 - DYNAMIC - Can CT DNA Allow us to Give Less Chemo in Stage II Colon Cancer

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4.62 - SHINE - Ibrutinib BR vs BR; Limitations to the trial

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4.61 - How CDC's Vaccine Safety Missed Cases Of Myocarditis

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4.60 - NEW JCO paper - AML, EFS, CR, CRi, and Surrogate validation - FDA & Methods

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4.59 - How to be a better reader of case control studies

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4.58 - Myeloma is a broken field - New BLOOD Paper!

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4.57 - COVID19 and the Failures of Public Health w/ Leslie Bienen

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4.56 - Fifth Installment of the brilliant Zeb Jamrozik

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4.55 - Compilation Of Recent Covid Monologues

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4.54 - Eric Collisson Professor, GI Oncologist, Physician Scientist

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4.53 John Ioannidis lectures the VKPrasad Lab about COVID19

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4.52 Vinay Prasad Gives a Lecture on COVID19 to a General Audience

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4.51 - Vinay Prasad is Interviewed by Kristina Jenei About Academic Medicine

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4.50 - Ivosidenib & Aza vs Aza, the AGILE, 6 huge problems; Journal club

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4.49 - Malignant Book Club Part 3 Audio

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4.48 - The Truth About RCTs In Cancer Medicine

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4.47 Malignant Book Club w/ Dr. Olivier Part 2 of 9

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4.46 - Cancer Monologue and Lecture #5 from VP's Class on How to Appraise Medical Literature

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4.45 - Malignant Book Club w/ Dr. Olivier Part 1 of 9

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4.44 - Cost Of Cancer Drugs - Basics In Cancer Drug Policy

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4.43 - VKPrasad Lab Update Part 2 With Timothee Olivier

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4.42 - Timothee Olivier, Geneva in the first Installment of VKPrasad Lab updates

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4.41 The Mask Debacle with Jacob Hale Russell

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4.40 H Gilbert Welch - Melanoma Screening; Blood Based Cancer testing; Lung CA screening

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4.39 Dr Zeb Jamrozik, ID ethicist, practicing doctor, great thinker

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4.38 COVID-19: Boosters for Adults and Teens, Paul Offitt, Testing, Myocarditis, Campus Restrictions

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4.37 MEMOIR & The Emperor Has No Clothes (a Critique of Cancer Care) with Dr. Christopher Booth

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4.36 Where Are We Now with COVID-19? with Dr. John Ioannidis

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4.35 Omicron, Travel Bans, Masks, Vaccine Mandates with Dr. Zeb Jamrozik

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4.34 ASH Lymphoma Updates: POLARIX, ZUMA 7, BELINDA w/ Papa Heme and DRG

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4.33 Melanoma: Tebentafusp, Stage Migration, Adjuvant Therapy, Training with Dr. Adil Daud

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4.32 Oral Azacitidine for AML and Nelarabine for T-ALL with Dr. Bernard Marini

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4.31 Neoadjuvant Radiation Therapy in Pancreatic Adenocarcinoma with Dr. William Hall

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4.30 COVID in Children and the US FDA Vaccine Advisory Committee with Dr. Cody Meissner

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4.29 Scientific and Ethical Failures of COVID-19 with Dr. Zeb Jamrozik

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4.28 Calling Out Unethical Clinical Trials, Melflufen, and Academic Oncology with Dr. Aaron Goodman

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4.27 Economics and Medicine with the Host of Freakonomics, M.D., Dr. Anupam Bapu Jena

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4.26 Recent Kidney Cancer Trials, Unethical Cancer Clinical Trial, & CASSIOPEIA

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4.25 A Critique of COVID-19 Health Policy with Infectious Disease Ethicist Dr. Zeb Jamrozik

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4.24 COVID-19: Moderna booster, Myocarditis, Progressivism, Social Media, Masks, Tests, J&J booster

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4.23 Access to Cancer Medicines, Standard of Care in Oncology, and the Oncology Value Paradigm

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4.22 Honoring Dr. Elilhu Estey and His Decades-Long Oncology Career

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4.21 Cognitive Errors in Medical Decision-Making with Dr. Daniel Morgan & COVID-19 Policy

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4.20 Vaccinating Kids and College Students, Boosters, Outdoor Masking, Bangladesh RCT, & more!

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4.19 Censoring: Not on Facebook, but in Kaplan-Meier Curves

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4.18 Dementia Interventions, Skills for Epidemiologists, & Aducanumab with Dr. Maria Glymour

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4.17 RCTs for Cancer Drug Approval with Dr. Saroj Niraula & Myeloma Studies with Dr. Manni Mohyuddin

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4.16 Treating Lymphoma, Histiocytic Disorders, Learning by Teaching, & More! with Dr. Bita Fakhri

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4.15 #AllCOVID-19: the Tough Questions About Policies Concerning the Delta Variant of COVID-19

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4.14 Evolution of GI Cancer Therapy, Editing JCO, Advice for Clinical Trialists with Dr. Alan Venook

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4.13 Lessons from Publishing 300 Peer-Reviewed Papers & What Telemedicine Will Do to Cancer Care

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4.12 Real-World Survival Outcomes for Pertuzumab and T-DM1 with Dr. Josee-Lyne Ethier

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4.11 CheckMate 274, PARADIGM-HF/Ernesto, POLO, & an AI Approach to Reducing Knee Pain

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4.10 A Deep Dive into CheckMate 649 with Dr. Jeffrey Bien

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4.09 Problems with the VISION Trial & Stool Transplant Plus Nivo for Metastatic Melanoma

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4.08 Implications for the Fate of Accelerated Approval from the ODAC Votes of April 2021

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4.07 Questions from a Medical Student with Emma Greenstreet and Dr. Vinay Prasad

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4.06 CAR-T, Oncology RCTs, Social Media, Myeloma, and Career Decisions with Dr. Rahul Banerjee

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4.05 Exodus from Academia and the Regretful FDA Approval of Aducanumab with Dr. Ameet Sarpatwari

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4.04 Treatment Algorithm for Follicular Lymphoma & Assessing RCTs

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4.03 Multiple Myeloma, Productivity Metrics, and Field Changes in Oncology with Dr. Nina Shah

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4.02 The History of Breast Cancer Research and Treatment with Dr. George Sledge

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4.01 Highlights from the 2021 ASCO Annual Meeting

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3.90 Redesigning Health Care, Overuse, Burnout, and COVID-19 Groupthink with Dr. Marty Makary

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3.89 How to Think About COVID-19 Policy with Rare Events and Declining Probabilities

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3.88 Behind the Scenes for the One-Year Anniversary of Malignant with Dr. Vinay Prasad

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3.87 Round Table on Multiple Myeloma Initial Therapy, High Risk, and Maintenance

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3.86 Lenvatinib plus Pembrolizumab or Everolimus for Advanced RCC with Dr. Karine Tawagi

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3.85 Med-Psych, Palliative Care, and Respect for Autonomy and Dignity with Dr. Joshua Briscoe

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3.84 DLBCL, Bad Cancer Drugs and Bad Twitter Users with Dr. Aaron Goodman

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3.83 MetaResearch, Reproducibility, Expertise, & Early Career Researchers with Dr. Ioana Cristea

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3.82 Classical Hematology Chat on CVT and VITT with Drs. Sven Olson and Joseph Shatzel

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3.81 Impact of COVID-19 on Sociology, Politics, and Democracy with Genève Campbell

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3.80 ESMO-Magnitude of Clinical Benefit Scale (ESMO-MCBS) with Drs. Bishal Gyawali and Nathan Cherny

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3.79 Sweden's Stance on COVID-19, Hydroxychloroquine, Schools, & Mask Data with Dr. Cathrine Axfors

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3.78 Astronomy, Being a Scientist, and the Culture of the Academy with Dr. Avi Loeb

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3.77 Reporting of Race in US FDA Registration Trials with Dr. Mark Lythgoe

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3.76 COVID-19 Transmission in Schools with Dr. Christopher Whaley and Dr. Neeraj Sood

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3.75 All Things COVID-19 with Infectious Disease Professor Dr. Paul Edward Sax

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3.74 Artificial Intelligence in Dermatology with Dr. Roxana Daneshjou

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3.73 CheckMate 577: Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer

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3.72 Industry Payments to US Physicians for Cancer Therapeutics with Dr. Daniel Meyers

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3.71 How Research Influences Policy with Dr. Kirsten Bibbins-Domingo

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3.70 The Motivation We Need to Reach the End of the COVID-19 Pandemic with Dr. Monica Gandhi

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3.69 Reporting of Postprotocol Therapies in Multiple Myeloma with Dr. Ghulam Rehman Mohyuddin

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3.68 A Career in Academic Medicine & Challenges of 2021 with Former Harvard Dean, Dr. Jeffrey Flier

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3.67 Thoughts on PhD Programs and Idecabtagene Vicleucel with Dr. David Russler-Germain

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3.66 COVID-19 Policies and Progressing Past Disagreement with Dr. Martin Kulldorff

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3.65 Banning Books, Social Media, & Medical Education with Dr. Adam Cifu

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3.64 A Legal and Philosophical View on COVID-19 with Samantha Godwin

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3.63 The Medical Scientist Training Program with Dr. David Russler-Germain

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3.62 COVID-19 Transmission, Vaccines, & Olaparib with Dr. Tom Beer

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3.61 The Neuroscience and Psychology of Recreational Drug Use in Adults with Dr. Carl Hart

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3.60 Drugs for Acute Lymphoblastic Leukemia with Dr. Bernard Marini

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3.59 Genetic Alterations Linked to SARS-CoV-2 Acquisition and Bad Outcomes with Dr. Nathan Pearson

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3.58 Expertise and Disinformation with Jacob Hale Russell

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3.57 Career Paths and Evolution of the Oncology Randomized Clinical Trial with Dr. Christopher Booth

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3.56 Quality of Control Groups in RCTs of Multiple Myeloma with Dr. Ghulam Rehman Mohyuddin

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3.55 Equity in Vaccine Distribution, Cancel Culture, and Zero COVID-19 with Dr. Matthew Smith

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3.54 The Passing of Dr. José Baselga

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3.53 Updates on COVID-19 and Looking Back Over the Last Year with Dr. Aaron Richterman

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3.52 Medicine, Leadership, SARS-CoV-2, and Social Media with Dr. Bob Wachter

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3.51 COVID-19 Modeling with Youyang Gu

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3.50 Evildoer Marty Makary [SHORT]

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3.49 The Role of Government in Public Health and in COVID-19 Policy with Dr. Robert Freudenthal

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3.48 The Predictive Value of High Tumor Mutational Burden with Dr. Luc Morris

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3.47 COVID-19 Vaccine Results, Messaging on a Patient Level, & Schools with Dr. Monica Gandhi

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3.46 COVID-19 Risk, Cases, and Transmission in K-12 Schools with Dr. Tracy Høeg

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3.45 USMLE Steps, Residency Match, & M.D. vs D.O. with Dr. Bryan Carmody

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3.44 The Role of Philosophy, COVID-19 Policy, and COVID-19 Exceptionalism with Dr. Alex John London

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3.43 Reviewing the Beat AML Master Trial

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3.42 Overdiagnosis and Cutaneous Melanoma Diagnoses with Dr. Adewole Adamson and Dr. Benjamin Mazer

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3.41 Building a Meta-Research Career and Constructing COVID-19 Health Policy with Dr. John Ioannidis

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3.40 COVID-19 Vaccines, Origin of SARS-CoV-2, and Pandemic Mitigation with Prof Francois Balloux

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3.39 Public Health Messaging on COVID-19 with Drs. Julia Marcus and Stefan Baral

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3.38 Oncology During COVID-19 & RCTs from Low- vs High-Income Countries with Dr. Christopher Booth

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3.37 Skepticism, COVID-19, and Debating Science in the Era of Trade-Offs with Jacob Hale Russell

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3.36 Sustainable Ex-Vivo Seafood with Dr. Arye Elfenbein

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3.35 The Secrets of Vermont in Taming the COVID-19 Pandemic with Anne Sosin

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3.34 COVID-19 From a Philosopher's Point of View with Dr. Matthew Smith

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3.33 Hematologic Malignancies and Transplantation with Dr. Aaron Goodman

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3.32 Publishing Original Thought in Medical Journals with Dr. Stephen Bradley

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3.31 Random Thoughts on Visiting Hospital Patients During COVID-19 and Norman Wang's Lawsuit

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3.30 Benefit and Risk of SpaceOAR with Dr. William Hall

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3.29 Censorship in Medicine with Jonathan Darrow

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3.28 Exploring the History of Medicine with Dr. Adam Rodman, host of Bedside Rounds

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3.27 All Recent Acute Myeloid Leukemia Drugs with Dr. Bernard Marini

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3.26 The Importance of Debate and Dialogue with Dr. Saurabh Jha

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3.25 Public Health Policy on the Risk of COVID-19 in Children with Dr. Alasdair Munro

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3.24 KEYNOTE-177 & Mathematic Models for Fighting COVID-19 with Dr. Wesley Pegden

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3.23 Capturing Your Audience with Dr. Zubin "ZDoggMD" Damania & JAVELIN 100 with Dr. Karine Tawagi

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3.22 New Podcast, Opening Schools with Dr. Vladimir Kogan, Virtual Learning with Dr. Carycruz Bueno

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3.21 Affirmative Action with Leah Litman, Cost Implications with Dr. DeMartino, & Dr. John Mandrola

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3.20 Public Health Messaging, COVID-19 in the U.S. Northeast, Journal Club with a Fellow

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3.19 COVID-19 and the AIDS Pandemics with Dr. Monica Gandhi & Classical Hematology Chat

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3.18 Social Media and News with Dr. Benjamin Mazer & Caplacizumab for TTP with Dr. Tem Bendapudi

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3.17 COVID-19 and Schools in Norway with Dr. Atle Fretheim & Cancer Biology with Dr. Anthony Letai

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3.16 Non-Drug Interventions with Dr. Margaret McCartney & Cancer Biology with Dr. Jason Sheltzer

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3.15 COVID-19 in Children with Dr. Alasdair Munro & Pandemic Public Health with Dr. Stefan Baral

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3.14 COVID-19 with Dr. John Ioannidis & Trial Eligibility with Dr. Mary-Elizabeth Percival

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3.13 COVID-19 and Schools, COVID-19 and Scott Atlas, and COVID-19 Policy

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3.12 TMPRSS2, Cancer Imaging with Drs. Becker and Woo, Clinical Epidemiology with Dr. Thomas Newman

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3.11 Experts, Lockdown, Affirmative Action, & COVID-19 and Hearts with Professor Darrel Francis

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3.10 Colon Cancer Screening, Vascepa Patent with Jonathan Darrow, PREVENTT with Dr. Toby Richards

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3.09 COVID-19 Risk, Financial Toxicity, & HALT-IT for Journal Club with Fellow Dr. Justine Ryu

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3.08 Racial Concordance in Birthing Mortality & HERO for Journal Club with Fellow Dr. Michael Burns

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3.07 Lung Cancer Omics and Mortality, PPIs and COVID-19, & RECIST with Dr. Elizabeth Eisenhauer

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3.06 COVID-19 Vaccine Access, ADAURA, QOTW, & Journal Club with Fellow Dr. Karine Tawagi

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3.05 LIVE! A Midsummer Night's Stream

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3.04 Listener Questions & MedTwitter and Risk-Benefit Profile of Ramucirumab with Dr. Bishal Gyawali

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3.03 The National Lung Matrix Trial & the Major Flaw of the SPRINT Trial with Dr. Mark Friedberg

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3.02 BONUS! National Clinician Scholars Program with Dr. Hilary Seligman

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3.01 Risk of COVID-19 Among Users of PPIs, Time to Treatment Initiation, & Dr. Lynora Saxinger

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2.60 BONUS! Cancer Meta-Research 101: The Lay of the Land of Cancer Research

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2.59 The Best Doctor, Selinexor, & Annotation Services for NGS with Drs. Katsoulakis and Kelley

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2.58 RECOVERY & Twitter, Academic Debate, and Transitioning Your Career with Dr. Andrae Vandross

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273

2.57 RECOVERY, Clinical Trials in the US, EFS, Writing, Dr. Raj Chetty, & Dr. Ian Tannock

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274

2.56 HER2CLIMB & Misinformation and Disinformation with Dr. Cailin O'Connor

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275

2.55 Hydroxychloroquine for COVID-19, ASCO, QOTW, Private Equity in Medicine with Dr. Jane Zhu

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276

2.54 Classical Hematology Chat on Thrombosis in COVID-19 & Drugs for COVID-19 with Dr. Walid Gellad

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2.53 Why Agreeing 65% with Someone is Important & COVID-19 Health Policy with Dr. Daniel Morgan

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2.52 Malignant Audiobook, PROfound trial, & Literature and Medicine with Dr. Adam Cifu

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2.51 BONUS! Clinical Trials Part 3

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2.50 Neil Ferguson, Ending Lockdown, & Updates on COVID-19 Management with Dr. Benjamin Singer

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2.49 COVID-19 Contrarians, Remdesivir, & Book Club on "Malignant" with OHSU HemOnc Fellows

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2.48 BONUS! Introduction to Malignant: How Bad Policy and Bad Evidence Harm People with Cancer

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2.47 Remdesivir, Cloth Masks, & Incentives for COVID-19 Drug Development with Dr. Ameet Sarpatwari

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2.46 Psychology Unearthed by COVID-19 Precautions & Polygenic Risk Score with Dr. Venk Murthy

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285

2.45 Viral Spread of SARS-CoV-2, Rationing Resources, "Evidence Fiasco", & Classical Hematology Chat

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2.44 ICU Management of COVID-19 with Dr. Benjamin Singer

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2.43 BONUS! Novel Coronavirus and the COVID-19 Response in Oregon with Dr. John Townes

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2.42 Quality-of-Life Measurement in Oncology, KnowYourTumor, & Question of the Week

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2.41 BONUS! Clinical Trials Part 2: Crossover and Control Arms

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2.40 BEACON part 2, NALA, & Molecular Pathology and Next-Generation Sequencing with Dr. David Carr

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2.39 Effectiveness of Newer-Generation Antidepressants with Dr. Michael Hengartner

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2.38 KEYNOTE-048, Academic Currency, & Trials in Low/Mid-Income Countries with Dr. Bishal Gyawali

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2.37 Careerism, Presenting Abstracts, Twitter and the K-Index, & Classical Hematology Chat

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2.36 Thought Leaders, NELSON, & Reliance on P Values in Cancer Trials with Dr. Sam Rubinstein

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2.35 BONUS! How to Keep Up with the New Information in Medicine

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296

2.34 Red Light, Pola for DLBCL, Hem/Onc Question of the Week, & TAILORx with Dr. Ali Khaki

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297

2.33 Olaparib and POLO & the Classical Fallacies of Cancer Screening with Dr. H Gilbert Welch

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298

2.32 BONUS! Clinical Trials Part 1: Thinking Better About Cancer Medicine

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299

2.31 Listener Questions, Responsibility of Reviewers, & Duration of Response with Dr. Bishal Gyawali

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300

2.30 Questions from a Medical Student & Epidemiology with Dr. Ellie Murray

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301

2.29 Time from Diagnosis to Treatment in AML and Real-World Data with Dr. Sherrie Aspinall

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302

2.28 Trastuzumab in Later Lines of Therapy for HER2+ Breast Cancer, Kaplan-Meier Curves, & Patreon

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303

2.27 BONUS! Use of Bone-Modifying Agents Among Medicare Beneficiaries with MM with Dr. Arjun Gupta

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304

2.26 Questions of the Week: Hematology/Oncology, USMLE Step 2 CK, & a bonus Hematology/Oncology

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305

2.25 Questions of the Week: Hematology/Oncology, the USMLE Step 2 CK, & One From a Med Student

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306

2.24 Questions of the Week: the USMLE Step 2 CK, Hematology/Oncology, & One From a Med Student

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307

2.23 Question of the Week & Ethics and Inefficiencies of Clinical Trials with Dr. Jonathan Kimmelman

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308

2.22 Question of the Week & EMR, Talking to Patients, and Being a Doctor with Dr. Robert Hirschtick

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309

2.21 Aiming for the Hard Targets & Harm From Screening and Overdiagnosis with Dr. H Gilbert Welch

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310

2.20 "Courageous Skeptics", Lenalidomide, QOTW, and a Political Conversation with Dr. Andy Saultz

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311

2.19 Remembering Dr. Bernard Fisher & Self-Diagnosis with Dr. Mark Lewis

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312

2.18 Questions of the Week, Talking About Toxicity, ASCO Guidelines Authors' COI with Dr. Eitan Amir

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313

2.17 Questions of the Week, BEACON, & Use of Subacuate Rehab with Dr. Jonathan Yeh

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314

2.16 FLAURA & What Truly Matters in the Career of an Academic Physician with Dr. Vinay Prasad

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315

2.15 Bonus! The Value of Progression-Free Survival as a Treatment Endpoint with Dr. Michael Raphael

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316

2.14 Questions of the Week & Qualifications of a Fellowship Applicant with Dr. Jeremy Cetnar

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317

2.13 BONUS! RCTs Supporting Approvals of Cancer Drugs by EMA with Dr. Huseyin Naci

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318

2.12 Questions of the Week, Ethics of RCTs, & Transmission and Medical Overuse with Dr. Dan Morgan

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319

2.11 Questions of the Week, When RCTs are Necessary, & AYA Oncology with Dr. Adam Duvall

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320

2.10 Questions of the Week: the USMLE Step 2 CK, the MKSAP, & Hematology/Oncology

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321

2.09 Questions of the Week & Informed Consent in Clinical Trials with Dr. Lynn Jansen

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322

2.08 Questions of the Week: the MKSAP, the USMLE Step 2 CK, & From a Med Student

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323

2.07 Translational Research & Physical Examination Pet Peeves with Dr. Adam Cifu

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324

2.06 Heart Failure, Choosing a Specialty, & the Bayesian Approach with Dr. Frank Harrell

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325

2.05 Reup! Cancer Screening 101 with Dr. Adam Obley

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326

2.04 Reup! Tumor-Treating Fields for Glioblastoma with Dr. Michael Hayes

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327

2.03 Dr. Charles Moertel and the Modern Oncologist & Cancer Screening 101 with Dr. Adam Obley

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328

2.02 BONUS! Improving Access to Prescription Drugs through Policy Change with Dr. Stacie Dusetzina

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329

2.01 Selinexor, ECHELON-2, Parachutes, Tumor-Treating Fields, & MedTwitter

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330

1.68 Voxeletor with Dr. Olson & Humanizing Cancer, Defining Cancer, and more with Dr. David Steensma

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331

1.67 MONALEESA-7 and the Cost of Cancer Drugs with Dr. Stacie Dusetzina

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332

1.66 Employing Medical Writers & Frequentist vs Bayesian Methods with Dr. Allen Pannell

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333

1.65 BONUS! Focusing and Building Your Presence on Twitter

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334

1.64 Effectiveness of Cancer Screening with Dr. Joaquín Chapa and POLO with Dr. Emerson Chen

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335

1.63 POLO, TITAN, & from ASCO: FDA Approval, Surrogate Endpoints, and Patient Experience

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336

1.62 Rates of Cancer Screening, BILCAP Outcry, Waterfall Plots and Response Rate, & Dr. Jeff Sharman

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337

1.61 Postpublication Metrics of RCTs, PCP Appointment Time, Bortezomib, & Dr. Christopher Booth

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338

1.60 I-PREDICT, Flawed Phase I Trials, & the Cost of Drugs with Dr. Daniel Hartung

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339

1.59 BONUS! Should Evidence Come with an Expiration Date? with Palmer Greene

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340

1.58 Magic Mouthwash with Dr. Arjun Gupta & Precision Oncology with Dr. Talal Hilal

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341

1.57 BONUS! Control Arm Quality in RCTs Leading to Anticancer Drug FDA Approval with Dr. Talal Hilal

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342

1.56 BONUS! Real World Data & the Search for Meaningful Cancer Care with Dr. Christopher Booth

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343

1.55 Role of a Professional Society & More with Dr. Cliff Hudis of ASCO

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344

1.54 Association of Patient Characteristics and Tumor Genomics with Clinical Outcomes & SABR-COMET

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345

1.53 CALGB 50303, REMoDL-B, & REMS, Orphan Drug Act, and Role of the FDA with Dr. Ameet Sarpatwari

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346

1.52 BILCAP & DOACs for Thromboprophylaxis in Patients with Cancer with Dr. Sven Olson

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347

1.51 BONUS! Study Time Reduction Using Surrogate End Points with Dr. Emerson Chen

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348

1.50 Replacing RCTs, Physicians on Twitter, Open-Access, & Orthopedics with Dr. Kathryn Schabel

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349

1.49 Student Questions, Boeing 737 Max, Pancreatic Surveillance, Leukemia Drugs with Dr. Elihu Estey

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350

1.48 Falsified Data in Meta-Analyses and the Expert Halo Effect with Dr. Stephanie Halvorson

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351

1.47 BONUS! Medical Reversal: Class Lecture

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352

1.46 BONUS! Personal Finances with Dr. Tom Beer

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353

1.45 Real-World Data, Gottlieb, & Using the EHR for Meaningful Improvement with Dr. Deborah Cohen

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354

1.44 BONUS! Screen Time and Children's Performance

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355

1.43 Andexanet Alfa with Dr. Tom Deloughery & National Medicaid Policy with Dr. John McConnell

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356

1.42 Caplacizumab for TTP with Dr. Sven Olson & Economics of Drug Pricing with Dr. Inma Hernández

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357

1.41 Geneva Oath and Financial Relationships Among Guideline Authors with Dr. Joshua Niforatos

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358

1.40 The World of Hematology with Dr. Thomas Deloughery

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359

1.39 Looking Back On a Tenure in Medicine with Dr. Alex Denes

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360

1.38 Lartruvo, New Directions for Cancer Trials, Gene Expression Profiling, & Dr. Miriam Knoll

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361

1.37 BONUS! Medical Reversal for a General Audience

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362

1.36 Generic Price Competition & Military Surgical Advances with Dr. Martin Schreiber

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363

1.35 BONUS! Conflict of Interest in Oncology

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364

1.34 Endpoints in ECOG-ACRIN 2511, Update to KEYNOTE-024, & Mentorship with Dr. Joseph Shatzel

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365

1.33 Guarantee-Time Bias & Trials, Philanthropy, and Cancer Research with Dr. Tom Beer

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366

1.32.1 Radiation Oncology with Dr. Brian Kavanagh

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367

1.32 Rating Metrics, Conflict of Interest in the News, & Radiation Oncology with Dr. Brian Kavanagh

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368

1.31 Ketogenic Diet, COMET-1 and COMET-2, the Health Insurance Marketplace with Dr. Jane Zhu

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369

1.30 BONUS! Clinical Trial Endpoints, Drug Approval, Incentives in Oncology

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370

1.29 RCT of Parachutes and Frameworks for Internal Medicine with Dr. Andre Mansoor

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371

1.28 Questionable FDA Drug Approvals and Building a Career with Dr. Chadi Nabhan

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372

1.27 BONUS! Medical Reversal

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373

1.26 Lesson From an ASH Abstract, Behind the Scenes of a Residency Program with Dr. Sima Desai

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374

1.25 Welch's Legacy, Interpreting NGS, Uncertainty over Pregabalin, Beyond EBM with Dr. Sam Edwards

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375

1.24 Useless Medical Conferences and Dr. Adam Obley on Vascepa, Fish Oil, Vitamin D and Methotrexate

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376

1.23 BONUS! Developing Technology with Fewer Reversals: Maybe We Need More Translation Failure

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377

1.22 Elo-Pom-Dex, Immunotherapy Combos, Inherent Bias, and the FDA with Dr. Erick Turner

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378

1.21 Nab-Paclitaxel in CCA, OS of PALOMA-3, Transparency, and Dr. Talal Hilal's Advice for Trainees

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379

1.20 Precision Oncology: Some Benefit, Mostly Hype and Mentorship with Dr. Andrae Vandross

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380

1.19 BONUS! Introduction to Cancer Drug Policy

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381

1.18 IMpassion130 and Hot-Spotting with Dr. Brian Chan

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382

1.17 BONUS! Interpretation of Cancer Clinical Trials

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383

1.16 BONUS! Crowdsourcing Data Analysis and Medical Reversal: Why 40% of What We Do is Wrong

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384

1.15 Minimally Effective Treatments, CheckMate 331, and Dr. Adam Obley on Low-Value Healthcare

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385

1.14 BONUS! Immunotherapy in Desperation and the Pennington Lecture: Myths of Medicine and Marketing

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386

1.13 KEYNOTE-189, Dr. Talal Hilal on MRD, and Medical Education with Dr. Adam Cifu

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387

1.12 BONUS! Evidence-Based Medicine Has Been Hijacked in Oncology

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388

1.11 Peanut Gallery, Research Parasites, Appendectomies, HRQoL and PFS, Dr. Bishal Gyawali

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389

1.10 Criticism via Twitter, PACIFIC, PCI for CAD, and Dr. Rebecca Cooney of The Lancet

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390

1.09 Response Rate in Phase I trials, JACOB, and MI, Stroke, and Metastasis as Hard Endpoints

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391

1.08 Hyperprolific authors, NCCN with Jeff Wagner, and Dr. Renee Dversdal on Ultrasounds

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392

1.07 Adjuvant Sunitinib in RCC, future of EBM with Dr. John Mandrola

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393

1.06 RELEVANCE, Jenny Gill, and Dr. Catherine Livingston of the Oregon Health Authority

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394

1.05 Cost and Efficacy of Cancer Drugs, ECHELON-1, Dr. Derrick Tao, and EBM with Dr. Martha Gerrity

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395

1.04: Nutritional Epi, Lenvatinib, Nivo and Ipi for Melanoma, and Dr. Avi O'Glasser

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396

1.03: RWE, Right to Try, Talazoparib, Nivolumab, and Dr. Andrae Vandross

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397

1.02: HemOnc Fellowship and Hype in Cancer Medicine with Dr. Jeremy Cetnar

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398

1.01: Introduction and Dr. Adam Obley

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