All Episodes

Ep. 113. Reason on Clinical Trials, Medical Tourism, and the Data the FDA Won’t See

Ep. 112: Tim Urban on Startup Cities, AI Safety, Longevity, and Building Better Societies

Ep. 111: Antonio García Martínez on Crypto, Network States, and Building New Cities

Ep. 110: Tomas Pueyo & Trey Goff On The Next Silicon Valley Might Be A New Country

Ep. 109: Jonathan Anomaly on The Future of Human Enhancement, Genetic Selection & Startup Societies

Ep. 108: The Buck Inst. President, Eric Verdin, on Pathways to Life Extension Acceleration: Alternative Pathways and Radical Hopium vs. Scientific Realism

Ep. 107: Sid Sijbrandij On Beating Cancer with First Principles, n = 1 Personalized Treatments and Special Access Regulatory Pathways

Ep. 106: Yaron Brook: Capitalism, Ayn Rand, and the Moral Case for Freedom

Ep. 105: Andrew Hessel: Programming DNA and Engineering the Future of Life

Ep. 104: Ruxandra Teslo: Clinical Trials, Drug Innovation, and the Bottleneck to Biotech Abundance

Ep. 103: Ian Huyett on Right to Try, Christian Techno Optimism, and Biotech Federalism

Ep. 102: Arjun Khemani: Zcash, Radical Privacy, and the New Renaissance

Ep. 101: Bryan Caplan: Pro Market & Pro Business, the Real Ethics of Entrepreneurship

Ep. 100: A Conversation with Dr. Mary Ruwart: The Lost Innovation Cost of the FDA, and How Founders Can Reclaim the Right to Build

Ep. 99: A Conversation with Cremieux - How to Tell Good Science from Junk, and What’s Next in US Biotech & Deregulation

Ep. 98: A Conversation with Adam Thierer: The War on Computation - Why AI Must Stay Permissionless

Ep. 97: Dr. Michael Levin on Bioelectricity, Anthrobots, and the Software of Life

Ep. 96: Digital Nomads’ Individual Sovereignty and Regulatory Hacking in International Insurance Markets - A Conversation with SafetyWing CEO Sondre Rasch

Ep. 95: The Philosophical Implications of Radical Life Extension - A Conversation with John Martin Fischer

Ep. 94: Jose Luis “Nintil” Ricón on Metascience, Longevity Biotech Pathways and Parallel Institutions

Ep. 93: Cush on Latin American Dynamism, Crypto Adoption, and Building Subcultures of Relentless Ambition

Ep. 92: Jack Scannell On Eroom’s Law In Drug Development

Ep. 91: JP Vergne on the Pirate Organization as the Innovators of Capitalism and Governance

Ep. 90: Unlimited Bio’s Journey to Launch a Prospera Biotech Company - with Ivan Morgunov & Dr. Anna Vakhrusheva

Ep. 89: Nathan Cheng On His Journey To Radical Life Extension, The LBF Roadmap To Solve Aging, and The Role Of Ideology

Ep. 88: Samo Burja on Great Founders, Institutional Change and the Fragility of Technological Progress

Ep. 87: Terence Kealey - Decentralized Science, Neo-Medieval Universities & Longevity Moonshots

Ep. 86: Anders Sandberg on Meta-Innovation, Governance Futurism and Approaches to Existential Risk

Ep. 85: Brian Armstrong On Accelerating Civilizational Progress Through Crypto And Longevity

Ep. 84: Joe Lonsdale On How To Fix Broken Institutions

Ep. 83: Bradley Tusk – The Uber Story, Applying Political Leverage, and Practical Advice For Entrepreneurs On How To Overcome Regulatory Roadblocks

Ep. 82: Alex Tabarrok Interviews Próspera CEO, Erick Brimen, on Crafting A Regulatory Platform to Unlock Entrepreneurship

Ep. 81: Vitalik Buterin on the Crypto-Longevity Nexus, Network States & Pop-Up Cities

Ep. 80: Naval Ravikant On Why The Future Is Brighter

Ep. 79: Fireside Chat with Bryan Johnson and Aubrey De Grey – Challenges In The Longevity Movement

Ep. 78: Fireside Chat with Balaji Srinivasan & Niklas Anzinger – Longevity As The Ultimate Technology

Ep. 77: Tyler Cowen – Unearthing the GOAT, Technological Progress in the Post-Great Stagnation Era and Special Economic Zones

Ep. 76: Iyinoluwa Aboyeji - Africa's Tech Mogul is a Policy Entrepreneur and City Builder

Ep. 75: Commons & Contracts, The Evolution of Peer-to-Peer and Community Governance w/ Michel Bauwens and Max Borders

Ep. 74: David Luftglass on the Promise of Uruguay SEZs for Export-Focused Industries, and Scaling A Global Cannabis Business

Ep. 73: Matthew Queen on Pillars of Modern Risk Management: Insurance, the Impact of Regulation and New Domiciles

Ep. 72: Magatte Wade on the Bureaucratic Obstacles for African Entrepreneurs, Misguided Development and Startup Cities as the Solution

Ep. 71: Richard Hanania on the Legal Origins of Woke, Nietzschean Liberalism and the Public Choice Approach to International Relations

Ep. 70: Energy from the Stars - Andrew Côté on Nuclear Fusion’s Path to Unleash Material Superabundance for Humanity

Ep. 69.2: Enter Vitalia - A Zuzalu-Inspired Network Society to Accelerate Longevity

Ep. 69.1: Janine Leger on Zuzalu's Future, Community Development & Overcoming the Loneliness Epidemic

Ep. 68: Jim Pethokoukis on How to Create the Sci-Fi World We Were Promised, Conservative Futurism and the Genesis Clock for Technological Progress

Ep. 67: Bob Haywood on 50+ Years of Creating Opportunity Zones in 174 Countries, Solution-Oriented Legal Engineering to Achieve China's Economic Miracle, Dubai's Rise & Fighting Poverty

Ep. 66: The World’s Greatest Living Regulatory Economist - Sam Peltzman’s Intellectual Legacy, Bill Gurley’s Tirade Against Washington and Regulatory Capture Revisited

Ep. 65: "Most Drugs Are Bad for You" - Robin Hanson & Sebastian Brunemeier Return, The Crisis of Health Outcomes, Sclerosis of Science and Special Jurisdictions as Solutions

Ep. 64: Olivier Roland on Escaping the Tyranny of Place, History Lessons About Technical Disruption for the Internet Age and the Staggering Ineffectiveness of AML-KYC

Ep. 63: David Friedman on his Intellectual Legacy - Search for Truth, the Economics of Different Legal Systems and Market-Driven Governance Innovation

Ep. 62.2: The Past, Present & Future of Living (2/2) - Jackson Steger on the Governance of Co-Living, and the Technology Shifts that Enable New Ways of Community

Ep. 62.1: The Past, Present & Future of Living (1/2) - "Mobility is Threatening to State Authority”: Thibault Serlet on Historical Patterns of Labor Mobility and the Genesis of Passports

Ep. 61: Dwarkesh Patel & Niklas Debate Existential Risk of AI, Technical Possibilities & Limitations and the Influence of Political Authority

Ep. 60: Adam Thierer on Evasive Entrepreneurship as Technology Liberation, Dystopian Misrepresentation by Popular Culture and the Dangers of Washington's Coming AI Regulation

Ep. 59: Simon Whitney on "From Oversight to Overkill", How an Obscure Bureaucracy Destroyed Medical Experimentation & Slowed Down the Engines of Scientific Innovation

Ep. 58: Malcolm Collins on Demographic Collapse, Reproductive Technologies Used Within the Pronatalist Movement and Why Charter Cities are Key to Build Technophilic Growth Cultures

Ep. 57: Primavera De Filippi on The Network State vs. Coordi-Nations, the Tragedy of the Commons as a Governance Challenge and New Institutional Structures for Global Cooperation

Ep. 56: Minicircle Chief Scientist on the Promise of Gene Therapy to Extend Life, Roatan's Potential as a Frontier Hub for Biotechnologists & Overcoming the FDA's Bureaucratic Obstacles

Ep. 55: Bryan Caplan on Breaking Bad Laws, Voters as Mad Scientists and the (Anti-)Politics of Overcoming Regulatory Gridlock

Ep. 53: Ex-FTC Regulator Neil Chilson on Applying Emergent Order In Technology Policy, Outcome-Based vs. Preventative Regulations & the Political Agenda to Capture The Internet

Ep. 52: Michael Huemer on Thinking Rationally, The Ethical Flaws of the Legal & Regulatory System and the Problem of State Authority

Ep. 51: Learnings from Zuzalu & the Ethereum Movement, Niklas' talk about New Cities & Network States x Technology and Upcoming Initiatives in Africa & Latam

Ep. 50: Cyber-Philosopher Alexander Bard on the Shamanoid Personalities at the Frontiers, The Religions of the Internet Age and the Coming Decentralized World Order(s)

Ep. 49: Brian J. Robertson on Holacracy, the Operating System for Antifragile Organizations & Society, Psychedelic Churches and the Path to Higher Order Consciousness

Ep. 48: Jonathan Hillis - Building a Network City from the American Wilderness, Combining Web3 & Real-World Development and Polycentric Community Governance

Ep. 47: Erik Voorhees on Separating State & Money, DAOs and Legal Engineering @ Decentralizing Finance 2023 - A Prospera Builders’ Summit

Ep. 46: John Cumbers on Synthetic Biology ("Synbio") - The Language of Life, Computational Biology & the Quest to Genetically Engineer the Organic World

Ep. 45: The Case Against Death - Philosopher Patrick Linden Is Arguing for Radical Life Extension

Ep. 44: Allison Duettman on The Foresight Institute's Mission To Charter the Frontiers of Technology (e.g. Nanotechnology, Longevity & AI) and Why Hope Should Guide Our Thinking

Ep. 43: Bootstrap City Rising - Ciudad Morazán, Providing Human Dignity Amidst Poverty and Honduras' Path to Massive Decentralization of State Power w/ Massimo Mazzone +4 More Guests

Ep. 42: Debating “The Network State” Part II, Balaji Srinivasan’s Bet, Education in a Free Society & More Riffs & Rambles with Trey Goff

Ep. 41: The Ultimate Guide to Próspera - Co-Founder & CDO Gabriel Delgado Ayau's Vision to Supercharge Human Flourishing Through Technology & Entrepreneurship

Ep. 40: Joey Krug - Investment Lessons from Traversing the Boundaries Between Traditional and Decentralized Finance

Ep. 39: Alex Tabarrok on the Dance between Centralization and Decentralization in City Governance, Baumol Effect vs. Regulation in Increasing Price Levels and Economic Insights for Entrepreneurs

Ep. 38: Human-Robotic Augmentation to Bridge Digital and Physical World, Reigniting Pride in Skilled Construction Work & Building A New City w/ The Circular Factory CEO Alicia Nahmad

Ep. 37: Solar Geoengineering with Stratospheric Clouds, the World's Thermostat to Master Climate and Why Science Needs A Bias to Action w/ Make Sunsets CEO Luke Iseman & Eli Dourado

Ep. 36: David A. Johnston on the Economic Foundations of Crypto & Web3, Decentralised Apps (dApps) and the Movement to Decentralize Everything that can be Decentralized

Ep. 35: Bret Kugelmass on Nuclear Power, Human Overreaction & Regulatory Capture and How A Nuclear Revival Can Launch Humanity to an Age of Superabundance

Ep. 34: Afropolitan Co-Founder Eche Emole on the Network State, Leapfrogging Technology and Nurturing a Builders' Culture To Create Superabundance for Africans

Ep. 33: Scott A. Beyer on Market Urbanism, The Magic of Latin American Green City Spaces & The First Report From Visiting 50 Private City Developments

Ep. 32: Patri Friedman On 1000x Growth From Cypherpunk Ideas Into Mainstream Tech Culture, Using Venture Capital to Build New Cities & The Ethics of Upgrading Governance

Ep. 31: Max Borders on Decentralization, Social Evolution and New Organisational Models for Firms, DAOs and Countries

Ep. 30: VC Lab's Adeo Ressi on Overcoming the Regulatory Barriers Set by the Dinosaurs & Creating Ethical VC Funds

Ep. 29: Dan Epstein on Regulatory Entrepreneurship, Redefining Industries and Globalising Innovation Through Venture Capital

Ep. 28: Thibault Serlet on Special Economic Zones - A Deep-Dive Into Their 1.000+ Year-Old History as Laboratories of Governance Innovation

Ep. 27: Eli Dourado on Supersonic Jet Flight, Energy & Climate Innovation and Regulatory Hacking

Ep. 26: Mark Lutter on How Charter Cities Can Propel Economic Growth and Technological Progress

Ep. 25: A First Synthesis - 10 Theses About Regulation's Impact on Innovation & Growth

Ep. 24: Autonomous Drone Delivery in Latam, International Aviation Regulation and Bold Emerging Market Governments Leading the Way Towards Innovation w/ ORKID CEO Santiago Pinzon

Ep. 23: DeFi Against the Machine - Learnings from the FTX Meltdown & Building a Decentralized Gold Standard for the 21st century w/ TheStandard.io CEO Joshua Scigala

Ep. 22: David K. Levine on Intellectual Monopoly, "Great Inventors" as Patent Trolls and the Lifecycle of Innovation

Ep. 21: Discovering the Secret of Ancient Nuclear Waste, a Forgotten Government Experiment Buried in Old Documents & the Quest to Produce Electricity Too Cheap to Meter w/ Oklo COO Caroline Cochran

Ep. 20: J. Storrs Hall - Bringing Back A Future Past With Flying Cars, Nano-Robots and Multi-Level Cities By Nurturing A Techno-Optimist Culture and a Unleashing Second Nuclear Age

Ep. 19: Accelerating Bitcoinization through Education - AmityAge Academy Founder Dusan Matuska on Moving to Prospera, Educating 100m People about Bitcoin and the Future of Money

Ep. 18: How IP-NFTs, Open Source Pharma & Decentralised Science (DeSci) Can Unleash the Power of Off-Patent Generic Drugs w/ Savva Kerdemelidis

Ep. 17: John Chisholm on the Decline of Entrepreneurship as a Stranded Technology and How to Unleash Your Inner Company

Ep. 16: Cancer - A Scientist Turned Entrepreneur Embarks On A Battle Against A Disease, and A Kafkaesque Medical System Holding Back Innovation w/ Yendou CEO Zina Sarif

Ep. 15: Sebastian A. Brunemeier on the LongBio Path to Immortality, Decentralised Science (De-Sci) Business Models to Supercharge Healthcare R&D and the Nexus Between Crypto and Longevity

Ep. 14.2: New Models in Higher Education (2/2) - How Financial Innovations Like Income Share Agreements Align Incentives and Unbundle the University w/ Quotanda CEO Grant Taylor

Ep. 14.1: New Models in Higher Education (1/2) - How Praxis is Beating College By Cutting Time to Enter the Labor Market by 80%+ and Costs by 90%+ w/ Praxis CEO Cameron Sorsby

Ep. 13: Michael Gibson on Learning from Peter Thiel, Backing 19-Year Old Vitalik Buterin and Self-Education as the Path to End the Great Stagnation

Ep. 12: Medical Cannabis, the Science Behind the Beautiful Plant and the Path to Regulatory Approval & Creating Patient Benefits for Millions in Latin America w/ Sandra Carillo

Ep. 11: The Catawba Digital Economic Zone - Tribal Governance to Build the Best Crypto/Web3 Jurisdiction in the World and Disrupt Delaware /w Joseph McKinney

Ep. 10: Economic Growth, Stranded Technologies & Creating A More Open World

Ep. 9: Debating "The Network State" by Balaji Srinivasan with Próspera CMO Trey Goff

Ep. 8: The Case Against the FDA

Ep. 7: Tom W. Bell on Law as the Software of Society, Open Source Legal Kernels and Competitive Governance

Ep. 6: Michael Strong on Exit Options from Public Education, the Failures of Schooling & the Purpose of Learning

Ep. 5: Bart de Witte on Open Innovation, Healthcare AI and the Narrative for the Future

Ep. 4: Jessica Flanigan on Patients’ Rights vs. Medical Paternalism, the Ethics of Human Challenge Trials and Accelerating Medical Innovation

Ep. 3: Robin Hanson on Decision-Prediction Markets in Firms, The Long Road to Innovation and the Future of Governance w/ Tom Bennett

Ep. 2: Medical Regulations and the Byzantine Journey for Patients to Access Life-Saving Drugs w/ Simone Azevedo & Henk Schuring

Ep. 1: Navigating the Regulatory Maze of International Finance, Banking in Emerging Markets and Crypto in Special Jurisdictions w/ Sean Pawley & Rasheed Griffith

Introduction to the Stranded Technologies Podcast