All Episodes
The a16z Show — 1,000 episodes · page 1 of 10
The Missing Infrastructure for AI Agents: Documents | Reducto’s Adit Abraham
What Happens When Everyone Has a Health Expert in Their Pocket? | OpenAI’s Karan Singhal
What Happens When Al Agents Can Spend Your Money?
Why Real-World AI Is Harder Than the Benchmark | EliseAI’s Mario Martone
Why AI Could Finally Fix Healthcare Access | Zocdoc CEO Oliver Kharraz
AI Can Write the Code. Can It Run the System? | Grepr CEO Jad Naous
When AI Agents Start Spending Your Money | Alex Rampell & Terry Angelos
Can Open Models Keep Up With the AI Frontier? | Nathan Lambert
Can AI Break Cryptography? What the Experts Actually Think
The Race to Recursive Self-Improving AI
Nick Bostrom: How Should We Navigate Superintelligence?
What Makes a Great Entrepreneur? | Ben Horowitz on Vintage x Vintage
Chips, Memory, and Power | Pat Gelsinger
Building the Cloud for an Agentic World | AWS CEO Matt Garman
How Valon Rebuilt a $13 Trillion Industry From Scratch
Building Defense for the Agentic Era: Kevin Mandia
The Top 100 Consumer AI Apps: Who’s Actually Paying?
David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion
Beyond the God Model | Alex Atallah & Amjad Masad
Why AI Agents Can Beat the Incumbents
Rebuilding the Internet for Privacy | Barrett Lyon on DoxxNet
The $1 Trillion AI Buildout | State of Markets
The Personal Agent Race Is Here | Anish Acharya & David Pawlan
AI Can Write Code. Why Isn’t Software Better?
Building a Team at AI Speed | Harvey’s Maggie Landers
Aaron Levie, Steven Sinofsky & Martin Casado: How Do You Secure a World of AI Agents?
The Reputation Graph of Silicon Valley | Introducing Cosign
The Case Against an AI Pause | Eddy Lazzarin
Amjad Masad on Rethinking College for the AI Era
Why a16z is Building a New School for the AI Era | Ben Horowitz
AI Safety Language Is Destroying the Debate | Steven Sinofsky
Nas, Grandmaster Caz, Steve Stoute & Ben Horowitz on Paying Hip-Hop’s Pioneers Their Due
What Makes a Consumer AI Product Stick? | Josh Elman
Databricks CEO on AI Pacing, Cyber Risk, and the Enterprise
The Next Frontier of AI Video Is Control
The AI-Native CRM
The Age of Body Futurism | Ruby Justice Thelot
Greg Brockman on Why OpenAI Says We’re Entering the AGI Era
World Models, Robotics, and the Future of 3D AI
Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast
What It Takes to Build a Startup | Andrew Chen & Matt Perault
How AI Is Rewriting the Power Law of Venture Capital
Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan
OpenAI Researchers on the Future of Mathematical Reasoning
Can Open Source Keep AI Power From Concentrating?
Your AI Doctor Is Coming | Julie Yoo
Aaron Levie on Why Open AI Wins
Fei Fei Li: The Race to Build World Models For AI
The $100B Niches Hiding Inside Payments
Inside Moderna’s Personalized Cancer Vaccine
Daniel Litt: The Mathematician's Guide to AI
Gavin Baker: Why AI Demand Is Outrunning Compute Supply
Why a16z Launched the Machine Age Fund | Jen Kha
Why 1,200 AI Agents Started Working Together | Ryan Greenblatt
The Infrastructure Behind the Machine Age
Inside Cursor: The Anatomy of a Generational Startup
The State of AI: Macro, Apps, and Consumer
The New Economics of AI | Martin Casado & Steven Sinofsky
Why Medical AI Needs a Referee | Protege's Engy Ziedan
Martin Casado on Where the Value Is Going in AI
Microsoft's Deputy CISO on Securing AI Agents
How Global Networks Are Reshaping Startup Success
How Whatnot Built a Global Marketplace
How Do You Defend Against AI That Can Hack?
Stripe’s AI Strategy: Build More, Not Less
Ben Horowitz and Travis Kalanick on Building Again
The Two Ways to Sell AI: Lighthouse or Landgrab?
Garry Tan on Taste, Agents and Founder Ambition
The CISO Playbook for AI Agents | Datadog
The Self-Improving Company | Kavak's AI Playbook
The Reality of AI-Powered Cyberattacks | Truffle Security & Socket
The Engine Powering Open-Source AI
Three Startups Reinventing Critical Infrastructure
OpenAI's Joshua Achiam: Did We Already Reach AGI?
Ruby Thelot on Internet Culture, AI, and the Future of Taste
Marc Andreessen and Chris Dixon: What’s at Stake in Crypto Regulation
How Enterprise AI Really Gets Deployed
AI for America's Small Businesses | Lassie
AI Micro Dramas, Generative Media, and the Future of Creativity
Fei-Fei Li on Spatial Intelligence and Robotics
Steven Sinofsky: AI Doesn't Need New Rules Yet
Ben Horowitz: The Fight Over Open Source AI
Sriram Krishnan on Open Source AI's Biggest Week Yet
Building the Physical AI Stack | Travis Kalanick on TBPN
Travis Kalanick Is Back | Building the Future of Industrial AI
Why Physical AI Is the Next Frontier | Applied Intuition
Hugging Face's CEO on Open Source AI, Model Routing, and the Future of Competition
Amjad Masad on Going Direct, Building Replit, and the Future of Software
Replay 2025: David Sacks on AI, Crypto, and America's Technology Future
From the Archive: Can Anyone Catch NVIDIA? | The Future of Chips and Infrastructure
Is AI a Bubble? | Gavin Baker on Data Centers, GPUs, and the AI Economy
Before Blockchains, There Was State Machine Replication
How Bitcoin Rewired a Classic Computer Science Problem
Mark Zuckerberg & Priscilla Chan: How AI Will Help Cure Disease
Adam Neumann: This Is How You Build Iconic Companies
Is Software Losing Its Head?
Don’t Follow Your Passion | Ben Horowitz’s Advice for New Graduates
a16z Goes Global: Why American Tech Must Lead the World
Outsmarting Uber: Why Bolt Wins in Europe
Rick Rubin on AI, Creativity, and The Way of Code