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All Episodes

The Bio Report — 630 episodes

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Title
1

Innovating ADCs with Dual Targeting and Smarter Delivery

2

Targeting the Brain’s Immune System in Alzheimer’s Disease

3

How Gilead Is Building Durable Oncology and Immunology Franchises

4

Protecting the Brain After Stroke

5

Turning the Thymus into an Engine of Immune Tolerance in T1D and Beyond

6

Unlocking Major Targets with Mini Proteins

7

Addressing a Data Problem to Enable AI-Drug Discovery

8

Turning Multi Specific Antibody Design into an Engineering Discipline with AI

9

Addressing the Treatment Gap in Ischemic Stroke

10

A Pipeline in a Product that Reimagines Control of Inflammation

11

Building a Genetics Engine to Crack the Target Bottleneck

12

Stopping Shape-Shifting Tumors with a First-in-Class Epigenetic Drug

13

Rewriting the Rules of Antibody Drug Design

14

Mapping Cellular Stress Biology to Tackle Undruggable Targets

15

Turning Abandoned Drugs into Breakthroughs

16

Targeting Cancer Survival Genes in Solid Tumors

17

Addressing Treatment Gaps in Gout

18

An Off-the-Shelf Cell Therapy to Calm Cytokine Storms

19

Slowing Disability in MS

20

Tuning, Rather than Blocking, Immunity in IBD

21

Intercepting Cancer When DNA Surveillance Fails

22

Targeting Psychosis in Alzheimer’s Disease

23

A Class Action Suits Moves RICO from Mobsters to Medicine

24

Outsmarting Resistance with Rhythm

25

Editing Away Autoimmunity at the HLA Source

26

Why Asia is the Emerging Epicenter for Global Biopharmaceutical Progress

27

Reprogramming Cancer from Within

28

A Strategic Turn from Obesity to Cancer

29

A One Two Gene Therapy Punch to Non-Muscle Invasive Bladder Cancer

30

Reprogramming T Cells to Cross the Brain’s Border

31

A Billion-Dollar Bet on AI-First Drug Development

32

Finding New Targets on the Surface of Misfolded Proteins

33

Targeting Tumors from the Inside Out

34

An Effort to Detect and Treat Alzheimer’s at Its Earliest Stages

35

The Year in Biotech and What’s Ahead for 2026

36

Developing an Alternative to Opioids for Post-Surgical Pain

37

Leveraging the Power of Vocal Biomarkers

38

Determining the Cause and Severity of Sepsis with a Point-of-Care Test

39

Separating Signal from Noise in Regenerative Therapies

40

Rewriting Drug Discovery with an AI-Multi-Omics Approach

41

Overcoming Chemoresistance and Activating the Immune System in Difficult-to-Treat Cancers

42

A Hub-and-Spoke Ophthalmology Company with an Eye for Innovation

43

An AI Collaborative that Welcomes All into the Fold

44

Hitting the Reset Button on Cellular Aging

45

Changing the Ovarian Cancer Treatment Landscape with a DNA-Mediated Immunotherapy

46

Why the United States Must Fall in Love with Biotechnology, or Take a Back Seat to China

47

Transforming Drug Discovery and Disease Research—One Cell at a Time

48

Scratching the Surface with a Novel Approach to Treating an Orphan Lung Disease

49

A Dual Action Approach to Treating MASH

50

Extending the Life of Transplanted Kidneys

51

Overcoming Antimicrobial Resistance

52

Using Targeted Radiotherapies to Treat Challenging CNS Cancers

53

Hitting Previously Undruggable Targets with Oral Therapies

54

Building Better Models of Human Diseases to Speed Drug Development

55

Preventing Opioids from Countering the Benefits of Cancer Immunotherapies

56

Better Living through Computational Chemistry

57

Outsmarting a Clever One

58

The Search for a New Approach to Male Contraception

59

Crafting a One-and-Done Epigenetic Editor to Tackle Hepatitis B

60

Fueling AI Drug Development with Patient Biology

61

The Search for Better Obesity Treatments

62

A Novel Approach to Treating Chronic Low Back Pain

63

A Biologic Designed to Treat Acute Exacerbations of Asthma and COPD

64

Turbocharging Drug Discovery with Health Data

65

Revolutionizing the Production of Biologics with Algae

66

Making Medicines for a World of People with Cancer

67

Harnessing Myeloid Cells to Attack Cancer

68

Drawing Lessons from the COVID Pandemic

69

A Bet that Myostatins Can Muscle Out Obesity

70

Making Whole-Eye Transplantation a Reality

71

Synbio Companies Come to Grips with the One “Omic” that Matters

72

Searching for Safer Pain Medications

73

Bridging the Translational Divide in Healthcare AI

74

Seeking Long-Term Pain Relief from a Drug-Free Injection

75

Engaging Hard-to-Target Receptors with Antibodies that Activate

76

An Insider’s View of the Patent Fights that Shaped the Biotech Industry

77

Restoring Balance to the Immune System in Allergic Diseases

78

Turning Natural Killers into Off-the-Shelf Therapies for Autoimmune Disease

79

Combining an Antibody and siRNA to Treat Hepatitis B

80

Looking at the Promise of GLP-1 Agonists Beyond Obesity

81

An Off-the-Shelf Cancer Vaccine Faces a Final Clinical Hurdle in NSCLC

82

A Nose for Attacking Brain Cancer

83

An Unnatural Approach to Undruggable Targets

84

Expanding the Drug Developer’s Chemical Universe

85

Take 100 Megabytes a Day and Call Me in the Morning

86

Extracting the Benefits of Psychedelics

87

A Magellan that Circumnavigates Active Binding Sites

88

A Very Meh-Ry Biotech Year and What’s Ahead in 2025

89

Using Light to Biomanufacture a Steak

90

Sit, Stay, and Heal: Bringing Precision Medicine to Dogs, then Humans

91

Targeting the Undruggable Proteome

92

Preventing a Deadly Disease by Detecting It Before It Becomes Cancer

93

Getting Tumors to Say “Eat Me”

94

Targeting the Dark Matter of the Genome to Treat Diseases

95

Using AI to Discover Small Molecule Alternatives to Biologics

96

A BET on a Novel Approach to Treat Autoimmune Conditions

97

Cell Therapies that Can Do a Solid for People with Cancer

98

Going to Extremes to Discover New Drugs

99

Targeting Senescent Cells to Treat Aging-Related Diseases

100

Bringing Cellular Diversity into Sharper Focus

101

Developing Cancer Therapies for When Damage Control Goes Awry

102

Delivering the Goods

103

Swimming in the New Oil

104

Does This Drug Represent “A Paradigm Shift for Small Molecule Drug Development?”

105

Exploring the Promise and Peril of CRISPR

106

Transforming Protein Engineering with Generative AI

107

Delivering Peptide Therapies Orally

108

Creating A Drug Delivery ARMMs Race

109

A Seek and Destroy Approach to Disease-Causing Proteins

110

Teaching Tolerance to Address Autoimmune Diseases

111

A Bet That the Next Blockbuster May Already Be Inside You

112

A Big Mac Attack to Fight Cancer

113

Getting Animated about Bioliteracy

114

Reshaping Clinical Trial Designs with Real-World Data

115

Using Generative AI to Produce Precise Gene Editors

116

Enabling the Nervous System to Repair Itself

117

Overcoming Barriers to Delivering Large Molecules to the Brain

118

Developing Complex Therapies to Tackle Complex Diseases

119

How Solving a Problem with Genetic Medicines May Solve Another with Infectious Diseases

120

Boosting the Power of Dendritic Cancer Vaccines

121

Overcoming Resistance in Cancer with Chemistry

122

Teaching an Old Drug a New Trick to Prevent Lyme Disease

123

A New Class of Cell Therapies to Target Solid Tumors

124

Targeting the Tumor Microenvironment with Lipid-Based Immunotherapies

125

A Company Born from a Father Who Wore His Heart on His Sleeve

126

Using AI to Improve Burn Care

127

A Home for Biotech in the City that Never Sleeps

128

Biopharma R&D Growing Stronger

129

The Benefits of Having a Multitude of Cins

130

Making ADCs Smarter and Safer with a Simple Twist of Fate

131

Targeting a Natural Repair System to Restore Brain Health

132

Programing Cells in a Predictable and Scalable Way

133

Why DNA May Be the Data Storage Medium of the Future

134

Scouring Genetic Variation within Our Cells for Drug Targets

135

Correcting Gene Dysregulation to Treat Diseases

136

Using Technology to Regain Abilities after Spinal Cord Injury

137

Why Drug Developers Have a Growing Interest in Targeting Mitochondria

138

Beefing Up Computational Muscle to Understand Molecular Activity of Drug Candidates

139

Targeting a Multitude of CIN in Cancer Cells

140

The Year in Biotech and What’s Ahead in 2024

141

Transforming Healthcare with Data

142

Realizing the Promise of IL-2 Therapies with AI

143

Unlocking Real-World Data to Improve Outcomes

144

A Silicon Valley Entrepreneur Investing at the Intersection of Tech and Biotech

145

A Company Betting Its Physics-Based AI Will Fuel a Quantum Leap in Drug Discovery

146

Detecting Alzheimer’s Disease Early through a Blood Test

147

Addressing Supply-Chain Challenges Underlying Drug Shortages with Synthetic Biology

148

Building Better and More Affordable Vaccines

149

Overcoming Resistance to Targeted Therapies

150

Using Tumor Gene Therapy to Overcome Barriers to Immunotherapies

151

Using AI to Generate Mini-Protein Therapeutics

152

Inhibiting Cell Death to Preserve Vision in Retinal Diseases

153

Leveraging Generative AI to Design Therapeutic Antibodies

154

Managing Pain without Addiction

155

Using AI to Match Cancer Patients to their Best Treatment Options

156

A Venture Capitalist’s View of the Current Biotech Landscape

157

Realizing the Therapeutic Potential of Cytokines by Making them Context Dependent

158

Targeting Cancer and Autoimmune Conditions with Donor-Derived EBV T Cells

159

Reprogramming the Tumor Microenviroment to Activate an Immune Response

160

Making Safer and More Effective Vaccines with Targeted mRNA

161

Addressing a Global Need with RNA Vaccines and Immunotherapies

162

Targeting Bacteria in Chronic Diseases

163

Targeting Solid Tumors with Off-The-Shelf CAR T Therapies

164

Reimagining the Development of Immunotherapies with a Venture Studio

165

Repairing the Body with Advanced Cell Therapies

166

Achieving Precision with AI Pathology

167

Inducing Potent and Durable T Cell Responses to Fight Disease

168

Developing Immunotherapies that Target the Drivers of Cancer

169

Using Phase 0 Trials to Bring Precision Medicine to Treating Brain Tumors

170

Restoring Feeling and Function to Damaged Nerves

171

Enlisting Vaccines in the Fight Against Chronic Diseases

172

Extending the Reach of Protein Degradation Therapies

173

Growing the Bioeconomy

174

Developing Targeted Therapies to Address Resistance in Cancer

175

It Takes a Village

176

Bringing Stick-to-itiveness to Regenerative Medicine

177

A Biopharma Downturn or Return to Trend

178

Treating Aging-Related Disease by Targeting Molecular Drivers of Aging

179

Engineering Better Cell Therapies for Cancers

180

Targeting a Regulator of Inflammation to Treat Alzheimer’s Disease

181

Enabling Regenerative Therapies without Immunosuppression

182

Making Vaccine and Biotherapeutic Production Fast and Affordable

183

Forcing Cancers to Reveal Themselves

184

Making Clinical Trials Diverse and Accessible

185

Mining Bugs for Drugs

186

A Company That Bets Its Therapies Will Click with Patients

187

A Company Where It takes Guts and Brains to Develop Drugs

188

Changing Outcomes with Data

189

Treating Psychiatric Conditions with Tripless Psychedelics

190

How AI Is Finding Its Way into Unexpected Places in Biopharma Companies

191

Searching the Dark Matter of the Proteome to Develop New Therapies

192

The Year in Biotech and What’s Ahead in 2023

193

Targeting a Novel Checkpoint to Treat Cancer and Autoimmune Conditions

194

The Growing Need for Biosecurity Vigilance

195

Enlisting Next-Generation Cytokine Immunotherapies in the Fight Against Cancer

196

Engineering Safer and More Effective Cell Therapies

197

Changing Drug Discovery for Neuropsychiatric Disorders with Phenotypic Screens

198

Using Virtual Reality-Guided Mindfulness to Treat Chronic Pain in Cancer Patients

199

Activating the Adaptive and Innate Immune Systems to Fight Cancer

200

A Longevity Fund Focused on Young Companies

201

Learning from “Elite” Responders to Develop Better Immunotherapies

202

Bringing Precision Medicine to the Treatment of Obesity

203

Expanding the Promise of RNA Therapies

204

Triggering a Systemic Immune Response Against Cancer

205

Targeting RNA Dysregulation in Cancer

206

Building a Pipeline of Next-Generation Kinase Inhibitors

207

Rethinking How Cell and Gene Therapies Are Made to Improve Accessibility

208

Developing Next-Generation Radiopharmaceuticals

209

Why Great Science and Data Aren’t Enough

210

Targeting Sugars that Let Cancers Evade the Immune System

211

Engineering Stem Cells to Withstand Targeted Therapies

212

Targeting a Convergence of Signaling Pathways that Drive the Growth and Spread of Cancer

213

Moving from Preservation to Restoration with Off-the-Shelf Cell Therapies

214

Using Gene Therapies to Treat Chronic, Inflammatory Conditions

215

Unlocking the Full Potential of Antibody Therapies

216

Combatting Superbugs and Emerging Viruses

217

How a Plant-Derived Gel Halts Bleeding in Seconds

218

Exploiting a Vulnerability in Cancers

219

Democratizing AI

220

A Rapid Onset Nasal Spray to Treat Mental Health Conditions

221

A Regenerative Medicine Company Puts Its Off-the-Shelf Vessel Replacements to the Test in Ukraine

222

Battling Resistance in Tumors with “Pan-Variant” Kinase Inhibitors

223

Treating Disease by Editing Genes in the Microbiome

224

Embracing the Promise of Natural Killer Cells in the Fight Against Cancer

225

Addressing Neurodegenerative Disease by Suppressing a Hyper Immune Response

226

Bringing Precision Medicine to Psychiatry

227

Attacking Neurodegenerative Diseases with Protein Degraders

228

Restoring Immune Activity While Suppressing Cancer Proliferation

229

A New Model for Preventing Life-Threatening Blood Clots

230

The Race to Live Forever

231

A Model for Moving from Breakthrough to Blockbuster

232

Building the Next-Generation of Cell and Gene Therapies

233

Building Small Molecule Drugs that Are Superior to Biologics

234

A New Class of Cancer Therapies Targets Solid Tumors with a Dual Action

235

A Pursuit of Off-The-Shelf CAR-T Therapies

236

Mapping the Human Proteome

237

Gene Therapy Provides Hope to Hemophilia B Patients

238

Making Data-Driven Medicine a Reality

239

A Neuroscientist Turned Venture Investor Discusses TechBio Investing

240

A Nonprofit Seeks to Make Cell and Gene Therapies Affordable Worldwide

241

Disposing Toxic Proteins to Treat Neurodegenerative Diseases

242

Repurposing a Drug for Parasitic Infections as a Targeted GI Therapy

243

Targeting Chronic, Low-Grade Inflammation to Address Diseases of Aging

244

The Year in Biotech and What’s Ahead in 2022

245

Restoring the Guardian of the Genome to Fight Tumors

246

Advancing a Cell Therapy with the Potential to Cure HIV

247

Harnessing More Efficient Organisms to Reshore BioManufacutring

248

Using Digital Health Technology to Bring the Trial to the Patient

249

Using the Body’s Housecleaning Mechanism to Target Undruggable Proteins

250

Advocating for the Extension of Healthy Life

251

Using Donated Living Skin as an Alternative to Animal Testing

252

A Platform to Scale the Production of Personalized Cell Therapies

253

Developing Small Molecule Therapies to Target Proteins Only Biologics Have Been Able to Hit

254

Targeting Solid Tumors with Oncolytic Viruses

255

Reinventing the Discovery and Cell Line Development of Biotherapeutics

256

Engineering Off-the-Shelf Cell Therapies to Target Solid Tumors

257

Democratizing Drug Discovery

258

Scaling Genetic Counseling Services with AI

259

Programming Cell Therapies to Overcome Solid Tumor Defense Systems

260

Using Liquid Biopsies to Diagnose Infectious Diseases

261

Striking Hepatitis B at Its Core

262

Modulating Serotonin with Psychedelics to Treat Neuropsychiatric Conditions

263

A Procedural Therapy Seeks to Address Type 2 Diabetes at Its Root Cause

264

Building a Better Path to Neurotherapeutics

265

Taking a Portfolio Approach to Immuno-Oncology

266

Engineering Life to Reach New Worlds

267

Targeting Cancer Drug Side Effects at Their Source

268

Mapping the Universe of Human Proteins

269

Fighting Disease by Modulating the Translation of Proteins

270

Fixing Biopharma’s R&D Productivity by Taking a Cue from the Tech Industry

271

An Affordable and Widely Available Drug Offers Global Hope against COVID

272

A Gene Therapy to Program the Body to Produce a Treatment for Osteoarthritis

273

A Test for Data-Driven Drug Development

274

Bridging the Gulf Between the Promise and Reality of Precision Health

275

Using Synthetic Biology to Craft One-Time, Programmable mRNA Therapeutics

276

Using a Digital Cognitive Behavior Therapy to Treat Diabetes and Heart Disease

277

Disrupting Pain Signals with Precision

278

A Diagnostics Company Moves to Developing Precision Cancer Therapies

279

Characterizing the Immunome at Scale

280

Delivering Oxygen to Tissue in Need

281

Using Gene Therapy to Create a Drug Biofactory within a Patient

282

Finding New Uses for TNF Inhibitors

283

Using AI to Map the Undiscovered World of Bioactive Compounds in Plants

284

Improving the Delivery of Drugs through Thin Film Freezing

285

Using CRISPR to Target RNA Instead of DNA

286

An Antisense Pioneer Brings Custom Treatments to Patients with Ultra-Rare Conditions

287

Managing Neurodegenerative Diseases with Better Data to Improve Outcomes

288

A Small Molecule Cancer Drug That Promotes an Adaptive Immune Response

289

Sloan-Kettering Spin-Out Harnesses AI to Diagnose Cancer

290

Bringing Innovation to Cell and Gene Therapy Manufacturing

291

Tapping Psychedelics for their Anti-Inflammatory Powers

292

Advancing Cell Therapies Beyond Cancer

293

How the Pandemic Transformed a Small Diagnostics Company

294

Eliminating Security, Privacy, and Regulatory Burdens with Synthetic Data

295

Using Computational Discovery to Build Better Immunotherapies

296

The Year in Biotech and What’s Ahead in 2021

297

Bringing Precision Cancer Care to Dogs

298

As COVID-19 Vaccines Ship, One Company Brings Innovation to the Vials

299

Advancing an Antibody to Prevent and Treat Cytokine Storms in COVID-19

300

Using AI Created Digital Twins to Accelerate Clinical Trials

301

Modulating RNA to Quell Disease

302

A Quest to Extend Life through Early Disease Detection

303

Modulating a Gatekeeper of Cellular Metabolism to Treat a Range of Diseases

304

Finding the Best Cell for the Job

305

Transforming Clinical Trials with Digital Technology

306

Designing Immunotherapies that Can Overcome Recurrence and Resistance

307

Extending Precision Medicine Beyond Cancer

308

Growing Biologics

309

An Experimental COVID-19 Vaccine Begins Human Clinical Trials

310

Speeding the Delivery of CAR-T Therapies While Cutting the Cost

311

Transforming Infused Biologics into Injectables

312

A Novel Approach to NASH That May Have Benefits for COVID 19 As Well

313

Will a Focus on Protein Dysregulation Help Prothena Break from the Fold

314

After FDA Set Back, AI Driven Drug Company Advances with New CEO

315

A Gamified Therapy System Helps People with Brain Injury Recover

316

Genentech Drug Offers Oral, at-Home Option for SMA Patients

317

Enabling Precision Medicine through Proteomics

318

Battling Drug-Resistant Fungal Infections

319

Making Colorectal Cancer Screening Less of a Pain in the Ass

320

Targeting Diseases of Aging at a Cellular Level

321

Cracking the Immune System with AI

322

Using AI to Improve Drug Companies’ Regulatory Performance

323

Delivering Biologics Orally

324

Turning Proteins into Device Coatings that Provide Therapeutic Benefits

325

Testing if an Approved Antiviral May Prevent COVID-19 Outbreaks

326

Using AI to Crack COVID-19

327

Why An Experimental Therapy for Inflammatory Disorders Could Help the Fight Against COVID-19

328

Modernizing Phage Therapy to Kill Multidrug-Resistant Bacteria

329

A Rare Disease Drug Hunter Turns His Attention to COVID-19

330

What It Will Take to Move Beyond the Pandemic

331

Reading, Writing, and Erasing the Way to Epigenetic Cancer Therapies

332

Better Immunotherapies Through Chemistry

333

Bringing the Trial to the Patient

334

Controlling the Activity of Cell and Gene Therapies with Precision

335

Why Soon-Shiong Thinks His Triangle Offense for Cancer Can Be Applied to COVID-19

336

COVID-19, Vaccine Development, and Global Health Lessons from Ebola

337

Improving Cancer Outcomes with Early Diagnosis

338

Making A Social Contract That’s Enforceable

339

Treating Alzheimer’s Disease as an Autoimmune Condition

340

Fishing for New Drugs

341

Thoughts on the State of the Antimicrobial Arsenal

342

A MedTech Company That Thinks Like a Biopharma

343

Tapping the Potential of Psychedelics to Treat Psychiatric Conditions

344

Quantifying Neurodegeneration with Precision

345

Orasis Developing Eye Drops as Alternative to Reading Glasses

346

Reversing Disease Signals

347

Turning Cold Tumors Hot

348

Stabilizing Neuronal Connections to Treat Cognitive Impairment in Alzheimer’s

349

Our Annual Biotech Review/Preview with STAT’s Adam Feuerstein

350

An Effort to Eradicate Preventable Blindness

351

Seeking Success Where Others Have Failed

352

A New Antibiotic with a Unique Mechanism of Action Hits the Market

353

Improving Health with Better Data

354

An Effort to Bioprint a Transplantable Human Heart

355

How Doctors Are Cracking Difficult Cases with a Social Network

356

Cala Health Hopes to Win Over Payers and Providers with Its Bioelectric Medicine

357

Shaping the Emerging Bioeconomy

358

A Belief that Early Interventions Will Be the Key to Treating Alzheimer’s Disease

359

Transforming the Study of Microbes with High-Throughput Technology

360

Using RNA Diagnostics to Predict Patient Response to Immunotherapies

361

How a Clever Business Model May Accelerate the Use of Companion Diagnostics

362

Building Cell Therapies with Switches to Modulate Their Activity

363

Using Synthetic Biology to Build Intelligence into Cell and Gene Therapies

364

A Therapeutic Approach Built on Protein Degradation

365

Harnessing AI to Improve Sales and Marketing Decision-Making

366

A Doctor’s Quest to Cure His Own Rare Disease

367

Athersys Advances Off-the-Shelf Stem Cell Therapy for Stroke

368

Enlisting the Innate Immune System to Fight Cancer and other Diseases

369

Using AI to Improve Clinical Development

370

Addressing the Challenge of Making Antibody-Drug Conjugates

371

Targeting Regulators of Genes to Treat Cancer

372

Harnessing the Immune System to Diagnose and Treat Cancer

373

Using Synthetic Biology to Produce Cannabinoids

374

EpicentRx Hopes Rocket-Fuel-Derived Drug Will Propel It

375

Using Fruit Flies to Personalize Cancer Therapies

376

Bridging the Gap Between Data and Knowledge with AI

377

How Virtual Reality May Change the Way Researchers Discover and Develop Drugs

378

Addressing the Challenges of Drug Development with a New Market

379

Addressing the Challenge of Producing Stem Cell Therapies with Consistency at Scale

380

Ensuring a Placebo Response Doesn’t Derail a Clinical Trial

381

Using AI to Find New Uses for Validated Drugs

382

Using Digital Health to Change Our Understanding of What Drives Disease

383

Cidara Advances Antiviral Conjugate to Treat and Prevent Flu

384

Building a Drug Empire on Undervalued Assets

385

Bringing Precision Medicine to Autoimmune Disease

386

Fighting Drug-Resistant Fungal Infections

387

Accelerating Early-Stage Biotechs

388

Agenus Advances Broad Immuno-Oncology Pipeline

389

Targeting the Right Proteins to Treat Neurological Diseases

390

A Treat Locally, Act Globally Strategy for Treating Cancer

391

Squeezing New Possibilities into Cell Therapies

392

Industry Calls for New Incentives to Spur Development of New Antibiotics

393

Company Seeks to Prove Marine-Derived Alzheimer’s Drug Is No Fish Story

394

Targeting the Plasma Proteome to Address Diseases of Aging

395

Teaching Scientists to Be Effective Communicators

396

Designing Small-Molecule, Immuno-Oncology Drugs That Act Like Biologics

397

Biohacking for the Masses

398

A Hearts and Minds Strategy for Cardiovascular Disease

399

A Drug Hunter Finds Greater Freedom at a Nonprofit Institute

400

Attacking IBD Through a Novel Pathway

401

Writing the Future of Drug Research with Bioink

402

An Effort to Develop Safer and More Effective Immunotherapies

403

The Year in Biotech and What to Watch in 2019

404

Why One Investor Is Betting on Platform Technologies to Change the World

405

Price Transparency and a Healthcare Policy Analyst’s Brush with the Healthcare System

406

How a Leading Health Sciences University is Working to Address Homelessness

407

Gecko Looks to Broad Applications in Tissue Reconstruction

408

The Search for Mediators of Aging

409

Using Drug Delivery Technology to Improve ADHD Therapies

410

How One Company Is Targeting a Growing Opportunity in Women’s Reproductive Health

411

Why an HIV Drug in Development Could Change How Cancer Is Treated

412

How the Rise of the Patient-Consumer Is Changing Clinical Trials

413

Bringing Real-World Monitoring to Autoimmune Disease

414

Using Real-World Evidence to Improve Drug Development

415

Enlisting Immunotherapies in the Fight Against Infectious Diseases

416

Tackling the Problem of Resistance in Chemotherapy

417

Engineering Bacteria for Therapeutic Benefit

418

The Promise of Organ-on-a-Chip Technology to Improve Drug Development

419

Harnessing AI to Fight Diseases of Aging

420

Transforming Clinical Trials with Digital Health Technologies

421

Why Foresite Capital is Betting Big on the Convergence of AI and Biotech

422

Why Public Health Systems Need to Be Better Prepared for Extreme Weather Events

423

Predicting the Unpredictable Off-Target Activities of Drugs

424

Why Clinics Providing Stem Cell Therapies not Approved by the FDA Are Creating Growing Concern

425

Making Biomedical Discoveries Sooner

426

Reinventing Drug Discovery with AI

427

Carrying Therapeutic Payloads Across the Blood-Brain Barrier

428

Harnessing Bacteria to Improve Skin Health

429

How One Accelerator Tries to Give Early-Stage Drug Developers an Edge

430

Making Synthetic Biology a Commercial Reality

431

Why Behavioral Economics May Turn Irrational Patients Rational

432

Pushing the Frontiers of Longevity

433

Is Hearing Loss a Necessary Price for Children to Pay for Life-Saving Chemotherapies

434

Why Diagnostics May Be Critical to Reshaping Alzheimer’s Drug Development

435

Why the Diversity of Genomic Data Matters

436

Why Biomarkers May Be the Key to Immuno-Oncology Success

437

Seeing Virtue in Patients

438

When Science Becomes a Cause

439

The Pursuit of Healthier, Safer, and More Humane Meat

440

A Hidden Killer and Why Patients Face Barriers to Accessing Promising New Drugs for It

441

Targeting the Regulators of Genes to Treat Disease

442

Price-Fixing Case Against Generic Drugmakers Widens

443

Outcomes Erode for Newborns and Mothers in Rural America as Hospitals Lose Obstectric Services

444

Why Drug Companies May Soon Become Health Technology Companies

445

After Facing Death, Former HR Director Helps Others Get a New Perspective on Life

446

Putting Physics to Work in the Fight Against Cancer

447

Why Aging Might Best Be Thought of as a Disease

448

Looking for a Better Alternative to Chemotherapy for AL Amyloidosis

449

A University Spin-Out that Incubates University Spin Outs

450

Understanding the Challenges and Opportunities of Patient-Centric Outcomes

451

How CellMax Hopes to Change the Diagnosis Cancer with Inexpensive Liquid Biopsy

452

How Surveillance and Data Are Bringing Precision to the Treatment of Prostate Cancer

453

Why Life Sciences M&A Should Heat up This Year

454

The Outlook for Biotech in 2018

455

The Year in Biotech and What to Watch in 2018

456

The Year in Immuno-Oncology and What to Watch in 2018

457

What the Approval of the First Digital Pill Means for the Future of Healthcare

458

Why Public Health Systems Need to Be Better Prepared for Extreme Weather Events

459

Former CDC Director Takes on World’s Leading Cause of Death

460

How a Public-Private Consortium Is Revolutionizing Cancer Drug Discovery

461

How Faulty Thinking Can Derail Life Sciences M&A Deals

462

Targeting Drug-Resistant Bacteria with an Ancient Enemy

463

A Bioelectronic Approach to Treating Autoimmune Diseases

464

Harnessing Patient Data to Improve Drug Development Efficiency

465

How Colorifix Is Trying to Turn the Textile Industry Green

466

Targeting Patients as Sick as Dogs

467

A Strategic Investor’s View of the Biotech Investment Landscape

468

Bringing Gender Diversity into Biotech Boardrooms

469

Why the FDA May Need to Rethink Its Approach to Gene and Cell Therapy

470

VBL Targets Brain and other Cancers with Novel Immunotherapy

471

What Will It Take to Transform Healthcare to a System Focused on Prediction and Prevention

472

Can a Direct Pitch to Patients Drive a Home Run for Obesity Drug

473

Why Companies Across Industries Need to Develop a Bio Strategy

474

Economist Argues Maximizing Shareholder Value Hurts Drug Innovation

475

Partnership Drives Development of Antibiotic to Combat Resistant Gonorrhea

476

CIRM-Funded Pipeline of Regenerative Therapies Advances

477

Technology Allows Drugmakers to Tag and Authenticate Individual Pills

478

Harnessing Mosquitoes to Fight the Spread of Infectious Disease

479

Biotech Industry Moves Towards a Patent Cliff

480

PvP Takes a Unique Approach to Treating an Autoimmune Disease

481

Uncertainty Hangs over the Biotech Sector

482

What Others Can Learn from COI’s Approach to Cost-Efficient Drug Development

483

Dyadic Seek to Bring Disruptive Technology to Biomanufacturing

484

Enlisting the Immune System in the Battle Against Alzheimer’s

485

Overcoming the Delivery Challenges of Gene Therapy

486

Brexit Sparks Battle to House the EMA

487

New Safety Concerns Identified After FDA Approval of One in Three Drugs

488

Why Climate Change Is a Public Health Concern

489

Reflections on the Progress and Promise of Personalzied Medicines

490

Curing Cancer with Math

491

How Healthcare Consumer Find and Use Price Information

492

Why Infectious Disease Represents a National Security Threat

493

Recent Mumps Outbreaks Raise Question If New Vaccine Is Needed

494

Proposed Legislation Would Weaken Genetic Privacy Protections

495

How Biomarkers Can Alter the View of and Approach to Alzheimer’s Disease

496

The Fight for Personalized Medicine Wages on Many Fronts

497

Big Pharma and the Growth and Outlook for Orphan Drugs

498

What the Recent Patent Ruling Means for the Future of Gene-Editing Technology

499

Weighing What Limits Should Be Put on Gene Editing

500

Enlisting the Immune System in the War on Cancer

501

Why Scientists Must Also Be Advocates

502

Sernova Eyes Range of Disease for Implantable Cell Technology

503

Stratus Wants to Demonstrate Its Telehealth Fluency

504

Regeneron Embraces Genetics as Fundamental to Drug Development

505

Despite FDA Setback, KemPharm Advancing Prodrug Pipeline

506

Using digital technologies to improve diagnosis and treatment of mental health patients

507

Biotech in 2016 and the Year Ahead with TheStreet’s Adam Feuerstein

508

Harnessing Gut Bacteria to Treat Disease

509

A Look at What’s Ahead for Biopharma in 2017

510

AMA Wants Docs to Have Seat at mHealth Table

511

Testing of New HIV Vaccine Carries Hopes of a Breakthrough

512

Centrexion Takes Aim at Pain with Growing Portfolio of Non-Opioid Therapeutics

513

Bringing Women into Biotech Boardrooms

514

Novartis Deal Validates Perlara’s Approach to Rare Disease Drug Discovery

515

Harvesting the Aquatic Microbiome for New Drugs

516

How TwoXAR Is Using Big Data to Accelerate Drug Discovery

517

Developer of innovative catheter for cancer drugs turns to crowdfunding

518

Harnessing Real World Samples and Data to Speed Biomedical Research

519

A Rich Pipeline Expected to Drive Industry’s Growth

520

Harnessing Biology to Transform the Economy

521

How a Predictive Diagnostic Can Reduce Preterm Births

522

Building Better Drugs for Psychiatric Disorders by Targeting the Causes

523

The Role of PBMs in the Controversy over Drug Pricing

524

Why a Rare Genetic Disease May Shed Light on Normal Aging

525

Battling Zika and Other Diseases Like It

526

Chronicling a Trailblazer of the Genomics Age

527

Great Progress, but Concerns Persist About Cancer Care in America

528

Improving Healthcare by Addressing the Most Challenging Patients

529

The Case for Chasing Unpopular Indications

530

Improving Drug Development through Better Use of Biomarkers

531

Measuring the Value of Incubators and Accelerators

532

Enlisting New and Old Tools to Combat Antibiotic Resistance

533

Advancing Cancer Care with New Diagnostic Tools

534

A Biotech Reinvents Itself and How to Price Drugs

535

Using Technology to Modernize Preclinical Development

536

Can the Biotech Industry Stay on Track through Innovative Pricing

537

Wall Street Turns Its Eyes to ASCO

538

Understanding the Disease It Never Was on House

539

Why the State of Innovation Is Encouraging

540

Can Market Forces Fix Drug Pricing

541

Digital Health Device Seeks to Push Beyond Cannabis to Test Food, Air, and Water

542

Why the Cancer Moonshot Offers a Chance to Rethink Funding Priorities

543

Medtronic Advances Toward an Artificial Pancreas

544

Using Real-Time Data to Detect HIV Outbreaks

545

Why Pharma Needs to Forge New Drug Pricing Models

546

Gensight Targets Gene Therapy on Diseases that Blind

547

A Vial Problem: How We Waste $3 Billion of Cancer Drugs a Year

548

The Havoc-Wreaking Zombies Lurking in Life Sciences Boardrooms

549

New FDA Chief Faces Challenges

550

Seeking a Best-in-Class Antibody at Bargain Basement Prices

551

Pharma Bro, Price Controls, and the Quest to Balance Innovation with Affordability

552

California’s Stem Cell Agency Plots Its Future

553

ViaCyte Pursues ”Functional Cure” for Type 1 Diabetes

554

Building a Better Pain Pill

555

Project GENIE Hopes to Make Precision Medicine a Reality

556

FDA Wants Industry to Guard Against Cybersecurity Risks of Medical Devices

557

Pharma’s Leadership Vacuum and Its Price to the Industry

558

Permanent R&D Tax Credit a Boost to Life Sciences

559

Biotech in 2015 and the Year Ahead with TheStreet’s Adam Feuerstein

560

Trends Shaping the New Health Economy in 2016

561

Declining R&D Productivity Continues to Plague Big Pharma

562

Searching for Solutions to Rising Specialty Drug Prices

563

Biohackers Seek a Faster, Cheaper Path to Insulin

564

A Scorecard to Improve Drugmakers’ Transparency

565

Forget the Chemistry Set, Mom, I Want a Bioreactor

566

Ensuring Biological Tools Benefit the Environment

567

New SEC Rules Open Crowdfunding to the Masses

568

Harnessing Biology to Address Global Challenges

569

Immunotherapies ETF Lets Biotech Investors Bet on Emerging Sector

570

Biotech Investors Turn Their Eyes to Policy Matters

571

Why the MedTech Industry Should Worry About Future Innovation

572

Rare Disease Drug Developer Shows Speed of Business Model

573

Ensuring Value-Based Care Addresses What Matters to Patients

574

California, Aid-in-Dying, and What We’ve Learned from Oregon

575

FDA Guidance on Names for Biologics and Biosimilars and its Implications

576

Understanding the Cost and Value of Cancer Therapies

577

Jimmy Carter’s Final Wish: Eradicating Guinea Worm

578

The Quest for a Pink Viagra

579

Free Speech Ruling May Force FDA to Rethink Off-Label Marketing

580

Drugmakers Often Late to Report Serious Side Effects

581

When Hospital Cause, Rather than Cure, Deadly Infections

582

Rethinking the Value and Price of Drugs

583

Harnessing Stem Cells to Test Drug Safety

584

CrowdMed Enlists the Wisdom of Crowds to Solve Medical Mysteries

585

Biotech’s Record Performance and Looming Threats

586

What a Decade of Investment Tells Us about the Health of Biotech

587

What Activist Investors Can Teach Biotech Companies

588

ALS Fight Carries Muller from Patient to Biotech CEO

589

Examining the State of Sleep

590

TheStreet’s Adam Feuerstein Previews ASCO 2015

591

Home-Brew Morphine, Dual Use Technology, and the Biologist’s Repsonsibilities

592

Reinventing Tech Transfer

593

Thinking Narrowly About Antibiotics

594

Promise Shown in Different Approach to Alzheimer’s

595

Innovative Drugs Drive Big Increase in U.S. Spending

596

Ensuring Digital Health Technologies Benefit Older People

597

How the Sugar Industry Influenced Research to Protect Its Interests

598

Examining The White House’s Plan to Combat Drug-Resistant Bacteria

599

Weighing Adverse Events to Get at a Drug’s Real Costs

600

How One Company Is Reinventing Drug Development

601

Why Patent Trolling Threatens Biopharma

602

Shifting Venture Investment Raises Concerns

603

Will Policy Triumph Over Politics in 21st Century Cures Act

604

Democratizing the World of Healthcare Analytics

605

Will Funding for Obama’s Precision Medicine Initiative Match Its Ambition

606

Should Investors Temper Their Enthusiasm for CAR-T Therapies

607

What to Do About the United States’ Declining Investment in R&D

608

Why Big Pharma Hasn’t Been Able to Fix Its Revenue Gap with M&A

609

Remembering Industry Pioneer Ron Cape

610

Moving from Chronic Therapies to Cures

611

What’s in Store for the Biotech Industry in 2015

612

A Look at the Year That Was in Biotech

613

Why Privacy Concerns May Limit Big Data’s Payoff

614

Calculating the Cost of Drug Development and What it Means

615

How New Funding Models Are Accelerating Drug Development

616

Telemedicine Grows, but Reimbursement Remains an Obstacle

617

The Power of IBM’s Watson Is Coming to an App Near You

618

Brittany Maynard and the Debate over the Right to Die

619

What’s Driving the Booming Market for Orphan Drugs

620

Why Interoperability Is Much More than a Technology Problem

621

The Lean Startup Takes Hold in the Life Sciences

622

Enlisting Monoclonal Antibodies to Combat Bacterial Resistance

623

The Forces Bringing Disruptive Change to Healthcare

624

How One Foundation is Getting the Biggest Bang for Its R&D Bucks

625

International Collaboration Seeks to Drive Breakthroughs in Progressive MS

626

Will Increased FDA Regulation of Diagnostics Speed or Slow Development of Personalized Medicine

627

Using Human Biology to Improve R&D

628

Reengineering Drug Discovery and Development

629

The Year in Biotech So Far and What’s Ahead

630

Epirus Sees Opportunities for Biosimilars Outside U.S.