All Episodes
The Bio Report — 636 episodes · page 1 of 7
A Gut-Level Pivot from Diabetes to a GLP-1 Off-Ramp
Targeting Residual Inflammation in Cardiovascular Disease
Neutralizing Tumor Acidity to Improve Cancer Immunotherapy
How a Breast-Milk-Derived Peptide Could Change Bladder Cancer Care
Targeting Visceral Fat with RNA Therapeutics
Engineering T-Cell Engagers for Solid Cancers
Resetting Severe Allergies at Their Cellular Source
Innovating ADCs with Dual Targeting and Smarter Delivery
Targeting the Brain’s Immune System in Alzheimer’s Disease
How Gilead Is Building Durable Oncology and Immunology Franchises
Protecting the Brain After Stroke
Turning the Thymus into an Engine of Immune Tolerance in T1D and Beyond
Unlocking Major Targets with Mini Proteins
Addressing a Data Problem to Enable AI-Drug Discovery
Turning Multi Specific Antibody Design into an Engineering Discipline with AI
Addressing the Treatment Gap in Ischemic Stroke
A Pipeline in a Product that Reimagines Control of Inflammation
Building a Genetics Engine to Crack the Target Bottleneck
Stopping Shape-Shifting Tumors with a First-in-Class Epigenetic Drug
Rewriting the Rules of Antibody Drug Design
Mapping Cellular Stress Biology to Tackle Undruggable Targets
Turning Abandoned Drugs into Breakthroughs
Targeting Cancer Survival Genes in Solid Tumors
Addressing Treatment Gaps in Gout
An Off-the-Shelf Cell Therapy to Calm Cytokine Storms
Slowing Disability in MS
Tuning, Rather than Blocking, Immunity in IBD
Intercepting Cancer When DNA Surveillance Fails
Targeting Psychosis in Alzheimer’s Disease
A Class Action Suits Moves RICO from Mobsters to Medicine
Outsmarting Resistance with Rhythm
Editing Away Autoimmunity at the HLA Source
Why Asia is the Emerging Epicenter for Global Biopharmaceutical Progress
Reprogramming Cancer from Within
A Strategic Turn from Obesity to Cancer
A One Two Gene Therapy Punch to Non-Muscle Invasive Bladder Cancer
Reprogramming T Cells to Cross the Brain’s Border
A Billion-Dollar Bet on AI-First Drug Development
Finding New Targets on the Surface of Misfolded Proteins
Targeting Tumors from the Inside Out
An Effort to Detect and Treat Alzheimer’s at Its Earliest Stages
The Year in Biotech and What’s Ahead for 2026
Developing an Alternative to Opioids for Post-Surgical Pain
Leveraging the Power of Vocal Biomarkers
Determining the Cause and Severity of Sepsis with a Point-of-Care Test
Separating Signal from Noise in Regenerative Therapies
Rewriting Drug Discovery with an AI-Multi-Omics Approach
Overcoming Chemoresistance and Activating the Immune System in Difficult-to-Treat Cancers
A Hub-and-Spoke Ophthalmology Company with an Eye for Innovation
An AI Collaborative that Welcomes All into the Fold
Hitting the Reset Button on Cellular Aging
Changing the Ovarian Cancer Treatment Landscape with a DNA-Mediated Immunotherapy
Why the United States Must Fall in Love with Biotechnology, or Take a Back Seat to China
Transforming Drug Discovery and Disease Research—One Cell at a Time
Scratching the Surface with a Novel Approach to Treating an Orphan Lung Disease
A Dual Action Approach to Treating MASH
Extending the Life of Transplanted Kidneys
Overcoming Antimicrobial Resistance
Using Targeted Radiotherapies to Treat Challenging CNS Cancers
Hitting Previously Undruggable Targets with Oral Therapies
Building Better Models of Human Diseases to Speed Drug Development
Preventing Opioids from Countering the Benefits of Cancer Immunotherapies
Better Living through Computational Chemistry
Outsmarting a Clever One
The Search for a New Approach to Male Contraception
Crafting a One-and-Done Epigenetic Editor to Tackle Hepatitis B
Fueling AI Drug Development with Patient Biology
The Search for Better Obesity Treatments
A Novel Approach to Treating Chronic Low Back Pain
A Biologic Designed to Treat Acute Exacerbations of Asthma and COPD
Turbocharging Drug Discovery with Health Data
Revolutionizing the Production of Biologics with Algae
Making Medicines for a World of People with Cancer
Harnessing Myeloid Cells to Attack Cancer
Drawing Lessons from the COVID Pandemic
A Bet that Myostatins Can Muscle Out Obesity
Making Whole-Eye Transplantation a Reality
Synbio Companies Come to Grips with the One “Omic” that Matters
Searching for Safer Pain Medications
Bridging the Translational Divide in Healthcare AI
Seeking Long-Term Pain Relief from a Drug-Free Injection
Engaging Hard-to-Target Receptors with Antibodies that Activate
An Insider’s View of the Patent Fights that Shaped the Biotech Industry
Restoring Balance to the Immune System in Allergic Diseases
Turning Natural Killers into Off-the-Shelf Therapies for Autoimmune Disease
Combining an Antibody and siRNA to Treat Hepatitis B
Looking at the Promise of GLP-1 Agonists Beyond Obesity
An Off-the-Shelf Cancer Vaccine Faces a Final Clinical Hurdle in NSCLC
A Nose for Attacking Brain Cancer
An Unnatural Approach to Undruggable Targets
Expanding the Drug Developer’s Chemical Universe
Take 100 Megabytes a Day and Call Me in the Morning
Extracting the Benefits of Psychedelics
A Magellan that Circumnavigates Active Binding Sites
A Very Meh-Ry Biotech Year and What’s Ahead in 2025
Using Light to Biomanufacture a Steak
Sit, Stay, and Heal: Bringing Precision Medicine to Dogs, then Humans
Targeting the Undruggable Proteome
Preventing a Deadly Disease by Detecting It Before It Becomes Cancer
Getting Tumors to Say “Eat Me”