All Episodes
The Hilarious World of Depression — 98 episodes
Welcome Back to The Hilarious World of Depression. Yes, It's a New Episode. In 2026.
Introducing Depresh Mode with John Moe: Joel Kim Booster Is In A Pit
Movies That Get Depression Right
Steven Page Camouflages Songs About Depression
Mike Birbiglia Faces His Darkest Fears and Puts Them On Stage
Free Chapters of The Hilarious World of Depression: The Book: The Audiobook
Emmy Blotnick Once Ate a Whole Head of Cabbage. Alone. In Silence.
Lulu Miller Treats Her Depression With Fish Research, Finds Fish Don’t Exist
Dave Holmes Puts the ADHD in Dave Holmes
Call A Friend, Find Out How They’re Doing
Lori Gottlieb Has Seen All Possible Sides of Therapy
Jameela Jamil Has an Ambitious Goal: To Feel Things
A Message From Inside John’s Closet. I Mean Office.
Theo Fleury: Trauma, stardom, and a downward spiral on the latest Tremendous Upside
THWoD Special: Tremendous Upside with Chamique Holdsclaw and Metta World Peace
Introducing Tremendous Upside
Depression’s Eleven Big Lies EXPOSED!
Darryl ”DMC” McDaniels Finds Therapy More Helpful Than Olde English 800
Mark Duplass Has Two Speeds: Go and Crash
Angelina Spicer Wants to Say Things Out Loud About Postpartum Depression
Miz Cracker Looks in the Mirror
Charlene deGuzman Has Unsexy Stories About Sex
Anil Dash Loves Social Media and Wants It To Change
Ryan Bingham Finds a Home and Settles Down
Heather B. Armstrong Nearly Dies Ten Times and It Works Out Great
Mara Wilson Had Great Opportunities and Difficult Challenges
Whitney Cummings Puts It Together and Stops Falling Apart
Pete Holmes Looks for Meaning and Membership
Jenny Lawson and Books That Get Depression Right
The Perils and Rewards of Travel
Just the Funny Parts
Solomon Georgio Is Doing Better
Jonny Sun Ended Up Here Somehow
Naomi Ekperigin Brings In Her Baggage, Unpacks It
Check-Ups on Gary Gulman, Linda Holmes, Janelle James, and “Steve.” Plus, Sock Opportunities
Aparna Nancherla Is Having a Harder Time Doing Something She’s Great At
John Ross Bowie and Jamie Denbo Don’t Need Your Suggestions For Their Life Improv
Adventures in Therapy
Guy Branum Goes to Minnesota, Gets Good Internet, Finds Self
The Hilarious NIGHT of Depression
Words: Am We Uses Them Good At Mental Health?
Scott Thompson Keeps Getting Back Up Again
Chris Gethard Does Not Avoid the Collision
Figuring Out Regular Adolescent Behavior vs. Alarming Disorder with Jen Kirkman
Neko Case Leaves Bad Places, Goes to Better Places
Your Amazing Therapeutic Jukebox
Mortified’s Dave Nadelberg Presents Your Shame Live On Stage
Open Mike Eagle Goes Outside And Meets People
Impostor Syndrome: True Tales, Tricks, and Tactics for When You’re Feeling Fraudulent
Thom Tran Is a Regular Standup Comic Except for the Part About Being Shot in the Head in Iraq
Andrew Zimmern Wrecks His Life, Rebuilds His Life, and Eats Weird Food
Special Episode: Mental Health First Aid and Lady Gaga’s Mom
How to Get Help
Highlights From A Hilarious Night of Depression
Hannah Hart Gets Drunk, Tries To Make Grilled Cheese, Gets Famous, Tries To Enjoy It
Ted Leo Stops Beating Up File Cabinets, Songs, Self
Rachel Bloom Finds Her Voice, Then Uses It To Sing About Stealing Pets and Moving to West Covina, California
Reggie Osse Puts It Together
Linda Holmes Leaves Law to Concentrate On Watching TV and It Works Out Great
Rhett Miller Really Hates That Brass Cat
Mike Brown Trains as an Engineer to Prepare for Comedy
Janelle James Discovers She’s a Comedian and Not a Gardener
Jenny Lawson is Very Fond of Creepy Smiling Dead Animals and Worries Quite a Bit
The Holiday Coping Mechanism Spectacular
Ana Marie Cox Is Not Really Edited Much At All
Julie Klausner Builds a More Confident and Dumber Version of Herself For Our Amusement
Jeff Tweedy Didn’t Want to Take His Doctor On Tour Because the Doctor Was Terrible
Patti Harrison Figures Out Who She Is and She’s a Woman Who Likes Gross Jokes
Gary Gulman Is a Brilliant Comedian and an Ineffective Offensive Lineman
Aimee Mann Discovers That Having Feelings About Terrible Things Is Perfectly Fine
John Green Falls Victim to Some Bad Fiction While Writing His New Book
Neal Brennan Gives Ketamine and Magnetic Impulses a Try
Margaret Cho Works Out A Lot And Makes People Upset In New Jersey
Wil Wheaton Is Really Hoping It’s All Worth It
Episode #PREVIEW: Season 2 starts Sept. 25!
Episode #PLACEBO: Imagine Depression as a Person and Describe Them
Episode #PLACEBO: How to Get Help
Episode #PLACEBO: Hitting the Nail on the Head
Episode #PLACEBO: John Darnielle of The Mountain Goats on where all that coping music comes from
Episode #PLACEBO: The Things We Tell Ourselves That Help
Episode #PLACEBO: Vol. 2 of Listeners’ Favorite Coping Songs
Episode #PLACEBO: Listeners’ Favorite Coping Songs
Episode #PLACEBO: Coping Ideas From a Real Live Sad Clown
Episode #PLACEBO: A Conversation with Ana Marie Cox
Episode #PLACEBO: Therapeutic Ukuleles, Therapeutic Penguins, Therapeutic Yarn
Episode #PLACEBO: The Return of Peter Sagal
Episode #PLACEBO: Bonus Episode of Terrible, Thanks for Asking to Celebrate #trypod
Episode #PLACEBO: Billy Joel, Intrusive Thoughts Named Steve, and Nocturnal Carpentry
Episode #9: Paul F. Tompkins Sees Dead Grass and Has Screwed Up Relationships
Episode #8: Baron Vaughn and His Inadvisable All-Cheerio Diet
Episode #7: Jen Kirkman, Bad Therapy, Good Therapy, and Nuclear Invasion
Episode #6: Supershow! Eight Comedians! One Chronic Mental Illness!
Episode #5: Andy Richter on Youthful Melancholy and Twisted Entertainers
Episode #4: Dick Cavett Tells Tales of Hollywood’s Secret Shame
Episode #3: Sam Grittner Finds a Funny Thing Happened On the Way to Suicide
Episode #2: Maria Bamford Talks Bipolar II While Her Pugs Eat Nilla Wafers
Episode #1: Peter Sagal Opens Up
Episode #0: The Hilarious World of Depression — coming soon!