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All Episodes

The Top Line — 128 episodes

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Title
1

What did we learn from Big Pharma’s Q2 results?

2

How consumerization is reshaping pharma marketing (Sponsored)

3

A genomics library for the AI era

4

The next frontier in patient support: Connected data, AI and personalized engagement (Sponsored)

5

Novo Nordisk’s CFO on the oral Wegovy rollout and beyond

6

Inside Noble’s connected approach to patient support (Sponsored)

7

Psychedelics, peptides and GLP-1s

8

GSK’s first lung cancer approval, a new IPO path and more

9

Why modern clinical trials need a finance-first strategy (Sponsored)

10

5 emerging biotech hubs

11

Operating at the speed of science: The new medical affairs playbook (Sponsored)

12

Decision readiness is the next AI advantage (Sponsored)

13

A $10B deal, China trial scrutiny and highlights from ADA 2026

14

The deal before the deal

15

FDA Breakthrough Therapy and RMAT: Strategic Decisions That Can Accelerate Oncology Development (Sponsored)

16

Ipsen R&D chief on pipeline discipline, partnerships and 2026 milestones

17

Why MRD is becoming central to oncology drug development (Sponsored)

18

Behind the headlines of ASCO 2026

19

Mesutoclax points to possible shift in high-risk MDS and AML (Sponsored)

20

Boston, China and the future of biotech

21

Why direct-to-patient is the future of pharma access (Sponsored)

22

BioAge CEO talks NLRP3 and ‘pipeline in a pill’ ambitions

23

Designing an agentic, future‑ready tech roadmap for emerging pharma (Sponsored)

24

Health execs persevere in new policy landscape

25

Revisiting Pharma’s tariff reality

26

Setting a new standard in prefillable syringe systems (Sponsored)

27

Scaling theranostics through access, safety and trust (Sponsored)

28

A pivotal time for an RNA pioneer

29

Accelerating clinical trials with precision logistics (Sponsored)

30

Can Trump’s deal with the UK become a model for similar drug price agreements?

31

Biomarkers are reshaping oncology trial design (Sponsored)

32

Fixing failed spray-dried formulations faster (Sponsored)

33

AI brings precision to pharma content decisions (Sponsored)

34

Roivant’s CEO thinks China is a ‘red herring’

35

The top 10 pharma R&D budgets of 2025

36

An update on the pharma industry’s reshoring effort

37

Pulse check on Lilly's GLP-1 fortunes

38

Avoiding 11th hour surprises in clinical trials (Sponsored)

39

What Xaira is building after its $1B fundraise

40

Patent expirations push biopharma industry toward a tougher 2026

41

As AI evolves, the modern R&D lab is changing

42

How physiology powers biotech innovation (Sponsored)

43

Autoimmune CAR-T: Navigating the FDA’s new regulatory playbook

44

Inside the sterile fill capacity crunch (Sponsored)

45

Trump's tariff threats, measured by manufacturing

46

Why patient access must keep pace with drug innovation (Sponsored)

47

What were the biggest clinical trial flops of 2025?

48

Community oncology’s growing role in the future of cancer care (Sponsored)

49

The biggest potential drug launches of 2026

50

How Mirum is Advancing Rare Disease Care Through Strategic M&A (Sponsored)

51

Why human expertise still matters in AI-driven med comms (Sponsored)

52

Biopharma's rebound keeping pace so far

53

JPM26: Sunshine, AI and the deals that weren't

54

From approval to value: Why evidence storytelling now matters (Sponsored)

55

Drug approvals went from crawl to sprint in 2025

56

Putting patients first: from buzzword to business imperative (Sponsored)

57

Beyond the AI hype: How life sciences can turn agents into a competitive advantage (Sponsored)

58

China’s biotech moment goes global, Zai Lab exec says (Sponsored)

59

Biopharma CEOs assess the road ahead in 2026

60

A year in review and what 2026 holds for biopharma and healthcare

61

From data to decisions: how Walgreens is powering smarter pharma strategies (Sponsored)

62

The biopharma dealmaking landscape and what to expect in 2026

63

Advocacy, access and the future of cancer care take center stage in new Health Matters episode (Sponsored)

64

2025’s Fiercest Women in Life Sciences are changing the game

65

Bayer’s collaborative model: Breaking silos to accelerate impact (Sponsored)

66

Inside Foresight’s mission to redefine cancer monitoring (Sponsored)

67

Biopharma industry gathers momentum in Q3

68

PreCheck pulse check: What the industry is saying about FDA’s production initiative

69

How Pharma Can Build Trust and Reach Patients in Health Marketplaces (Sponsored)

70

Biotech Graveyard

71

Fierce 15: Where are they now?

72

Salesforce’s Mark Sullivan: AI and agentic systems will redefine life sciences (Sponsored)

73

Unpacking the FDA transparency push on CRLs

74

How Boehringer Ingelheim is buttressing its US business

75

AI is changing drug safety, but governance sets the guardrails (Sponsored)

76

A whirlwind week for pharma

77

Fierce Biotech's Fierce 15

78

Rebuilding trust in pharma in the age of misinformation

79

Schrödinger taps AI to speed drug discovery (Sponsored)

80

Inside the commercial growing pains of hemophilia gene therapies

81

A rare kind of leadership, 30 years in the making

82

Former FDA Chief Scott Gottlieb talks drug pricing, access and innovation (Sponsored)

83

Big Pharma bounces back in Q2

84

The battle of the obesity drug heavyweights

85

Is Trump’s MFN pricing order more bark than bite?

86

Rebuilding trust: compassionate communication and public health (Sponsored)

87

Untangling Sarepta’s gene therapy fallout and a growing trust deficit

88

Making sense of China’s R&D ascent

89

AI, mentorship and finding your voice in pharma marketing

90

Biopharma layoffs aren't letting up

91

Peter Pitts talks FDA direction, industry communication (Sponsored)

92

Teva’s CEO shares ‘Pivot to Growth’ progress

93

AbbVie, ADCs and the future of cancer care

94

Inside Fierce Medtech's Fierce 15

95

Inside ASCO 2025: Big data drops and a towering campaign

96

Forging the future of cell therapy: Bayer and BlueRock’s unique journey (Sponsored)

97

Science-led storytelling takes center stage in pharma communications (Sponsored)

98

Biopharma briefing: Q1 trends, gene therapy updates and ASCO preview

99

A Fierce breakdown of the 'most favored nation' executive order

100

Angela Hwang on her pivot from Big Pharma to biotech

101

ElevAAte and the push for East Asian American leaders in biopharma

102

Angus on Angus: A Fierce oncology discussion

103

Navigating Trump’s tariffs for pharma

104

Q1 biopharma layoff trends, plus expectations for Q2

105

A closer look at pharma's top R&D budgets

106

What diversity means in medtech

107

5 Key Questions About Precision Patient Marketing—Answered (Sponsored)

108

A closer look at pharma’s top patent losses in 2025

109

Agenus CMO touts immunotherapy advances on The Top Line

110

Breaking down pharma’s fourth-quarter sales boom

111

Inside the Future of Aseptic Manufacturing with GRAM (Sponsored)

112

Bridging the gap from clinical trials to real-life HIV care (Sponsored)

113

A look at biotech's biggest money raisers of 2024

114

Research reveals ‘ticking DNA clock’ behind Huntington’s disease

115

What were the biggest clinical trial flops of 2024?

116

A heartwarming roundup of cardiovascular news and most-loved stories

117

Looking ahead at the most anticipated drug launches of 2025

118

What to expect from the biotech IPO market in 2025

119

Recapping the 2025 J.P. Morgan Healthcare Conference

120

Fierce's forecasts for the next year in biopharma

121

An additional treatment option with TAGRISSO® (osimertinib) (Sponsored)

122

Breaking down the 55 new drug approvals of 2024

123

Fierce 50 honorees look ahead: AI, rural health, antibiotic resistance, maternal care and more

124

Novo Nordisk’s chief scientific officer looks to the future of GLP-1s

125

What can we learn from 2024’s biotech IPOs?

126

Meet 2024’s fiercest women in life sciences

127

Misconduct and the future of neurodegenerative disease research

128

Dig into this year’s Fierce Biotech Graveyard, layoff numbers