The Science of Saving Millions | Mikael Dolsten, Fmr. CSO of Pfizer

EPISODE · Nov 6, 2025 · 1H 29M

The Science of Saving Millions | Mikael Dolsten, Fmr. CSO of Pfizer

from Nucleate Podcast · host Nucleate

Time Stamps[00:44] — Introduction to the Nucleate podcast and Mikael Dolsten.[02:42] — Mikael shares his upbringing and academic journey at Lund University, highlighting the influence of mentors.[05:46] — Transitioning from academia to the pharmaceutical industry, driven by curiosity and patient needs.[19:18] — Reflecting on the pressures and leadership style of managing thousands of scientists at Pfizer.[39:56] — Highlights of vaccine development, particularly Pfizer’s role in COVID-19 vaccines and global impact.[51:09] — Behind the scenes of developing Paxlovid during COVID-19 and Mikael’s personal connection to the pandemic.[1:05:15] — Traits Mikael looks for in founders: the value of humility, talent, and collaborative culture.[1:12:05] — How to support early-stage biotech companies while maintaining entrepreneurial spirit and adaptability.[1:13:41] — Mikael’s insights into the evolving role of AI in drug discovery and precision medicine.[1:23:32] — Rapid-fire Q&A: personal reflections, career advice, and influences outside of science.

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The Science of Saving Millions | Mikael Dolsten, Fmr. CSO of Pfizer

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