“Down syndrome is the chromosomal abnormality that you can…” — Dwarkesh Podcast at 57:21
“Down syndrome is the chromosomal abnormality that you can survive. All the others just kill the embryo. And so we never see them. But Down syndrome occurs a lot. And there are many other lethal mutations. And as you go to less damaging ones, there are enormous numbers of less damaging mutations that are degrading…”
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