IMNano

Picture this: Shas started with a master's in water purification, dove into the world of engineering as a lab manager, flirted with the idea of becoming a medical scientist, and finally found his calling in the cutting-edge field of direct laser writing. Along the way, he has developed a passion for sharing these experiences and the incredible science behind them. In this nanolife episode, we'll explore the twists and turns of Shas' scientific careers, demystify complex concepts, and chat with him on his take of the road less traveled.  Shas's socials: https://www.linkedin.com/in/shasvat-rathod/ https://scholar.google.ca/citations?user=I70vO7cAAAAJ&hl=en

Check out are awesome nanolife interview with Prof Esmail Doustkhah from İstinye Üniversitesi in Turkey! He is organizing the amazing Nanotech Eurasia conference, and it is open for all to attend! Check it out here: https://eurasia-nanotech.istinye.edu.tr/en Stay curious!

Delve into the fascinating journey of Marina, exploring her experiences, challenges, and triumphs on her way to becoming a Professor in Mechanical Engineering at York University, Canada. She does many projects in water and air purification as well as energy and her lab is growing! Contact Prof Marina here : Marina Freire-Gormaly, PhD, EIT, LEED GAAssistant ProfessorDepartment of Mechanical EngineeringFaculty of EngineeringYork [email protected] https://freire-gormaly.lab.yorku.ca/people/

Menstrual blood is usually discarded but it actually contains a plethora of biomolecules that can tell us information about your health! CELLECT, a start-up founded by CT Murphy from the University of Waterloo, aims to use menstrual blood and nanotechnology solutions to diagnose HPV and cervical cancer. Tune in to this episode to learn more! About CT Murphy: CEO and Founder of CELLECT. She was awarded the Waterloo Institute for Nanotechnology (WIN)- Velocity scholarship, Velocity's Up Start Program, and Cornerstone Program. Her company was also recently covered by the Canadian Broadcasting Corporation (CBC). You can follow her LinkedIn here! Intro/Outro music: Music by ⁠minwbu⁠ from ⁠Pixabay

Super amazing chemistry References: Ruizhe Chen et al.,Alcohol-alcohol cross-coupling enabled by SH2 radical sorting.Science383,1350-1357(2024).DOI:10.1126/science.adl5890 https://chemistry.princeton.edu/news/macmillan-lab-scores-alcohol-alcohol-cross-coupling-method-after-long-effort/#:~:text=The%20method%3A%20achieving%20alcohol%2Dalcohol,by%20powerful%20SH2%20radical%20sorting.&text=The%20alcohol%2Dalcohol%20paper%E2%80%94the,salt%20to%20form%20activated%20adducts.

The Nobel Prize winning scientists, Frances Arnold, has done it again! Her team have use directed evolution to engineer enzymes that can break down the strong carbon-silicon bonds found in many products we use everyday! Reference: Nicholas S. Sarai et al. ,Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes.Science383,438-443(2024). DOI:10.1126/science.adi5554 Intro/Outro music: Music by ⁠minwbu⁠ from ⁠Pixabay

Time for a nanolife interview with the one and only Dr Thomas Mortelmans who delves deep into his medical biosensor and how he came out his various inventions! Check out his main biosensor work that we talk about here: ACS Appl. Nano Mater. 2022, 5, 1, 517–526 doi.org/10.1021/acsanm.1c03309 And you can follow and connect with Tom here: https://www.linkedin.com/in/thomas-mortelmans-ph-d-066a9a83/ https://orcid.org/0000-0002-0677-5857 ,

In this lit update we talk about a carbon nanotube sensor discovery that shows the current in a carbon nanotube device can pass parallel or perpendicular to the tubes and the results will be different! Reference: https://pubs.acs.org/doi/10.1021/acs.nanolett.3c02555  Nano Lett. 2023, 23, 21, 9817–9824

Let's review what we have accomplished, some of the missed research we didn't get to cover, and our favorite research in 2023! Intro/Outro music: Music by ⁠⁠⁠minwbu⁠⁠⁠ from ⁠⁠⁠Pixabay

Lit-Update Meet the Expert! where we get to dig deep into papers with the scientist themselves! Have you ever wondered how changes to your normal schedule affects your health? Tune in to learn more about circadian disruption and health from Stéphanie Abo based on her paper "Can the Clocks Tick Together Despite the Noise? Stochastic Simulations and Analysis" published in SIAM Journal on Applied Dynamical Systems. Stéphanie is a PhD Candidate in mathematical and computational biology at the University of Waterloo. Her academic research primarily explores the interaction between the circadian clock and metabolism in healthy and disease states (e.g., diabetes, bacterial infections). I use both data-driven and mechanistic modelling technique (PDEs, ODEs, stochastic DEs, kinetic theory and mean-field limits, agent-based modelling, and statistical methods). References: Abo, S. M. C.; Carrillo, J. A.; Layton, A. T. Can the Clocks Tick Together Despite the Noise? Stochastic Simulations and Analysis. SIAM J. Appl. Dyn. Syst. 2023, 22, 850-877 DOI:10.1137/22M147788X. Intro/Outro music: Music by ⁠⁠minwbu⁠⁠ from ⁠⁠Pixabay

Talking about the 2023 Nobel prize in physics used in this recent paper "Functional Group Modulation in Carbon Quantum Dots for Accelerating Photocatalytic CO2 Reduction" Zhikang Liu, Weidong Hou, Huazhang Guo, Zeming Wang, Liang Wang, and Minghong WuACS Applied Materials & Interfaces 2023 15 (28), 33868-33877

Failed experiments are usually hidden in our notebooks and computer, not shared in the literature, but they're important for the scientific process! In this podcast, we'll discuss how it's also important for machine learning assisted chemical experiments. Reference: F. Strieth-Kalthoff, F. Sandfort, M. Kühnemund, F. R. Schäfer, H. Kuchen, F. Glorius, Angew. Chem. Int. Ed. 2022, 61, e202204647; Angew. Chem. 2022, 134, e202204647. Intro/Outro music: Music by minwbu from Pixabay

In this lit update we discuss some super cool new research that uses aerosol jet printing to apply a solution of COF/carbon nanotubes to make nanocomposites. Tune in the for breakdown! References: Bradshaw, Nathan P., Zoheb Hirani, Lidia Kuo, Siyang Li, Nicholas X. Williams, Vinod K. Sangwan, Lindsay E. Chaney, Austin M. Evans, William R. Dichtel, and Mark C. Hersam. "Aerosol‐Jet‐Printable Covalent Organic Framework Colloidal Inks and Temperature‐Sensitive Nanocomposite Films." Advanced Materials (2023): 2303673. Intro/Outro music: Music by minwbu from Pixabay

Strong heat-activated artificial muscle to move artificial hands and robotic worms?! Tune in to learn more how scientists from Korea and France used graphene and liquid crystal elastomer to develop this human-muscle inspired technology! Reference: Kim, I.H., Choi, S., Lee, J. et al. Human-muscle-inspired single fibre actuator with reversible percolation. Nat. Nanotechnol. 17, 1198–1205 (2022). https://doi.org/10.1038/s41565-022-01220-2 Intro/Outro music: Music by minwbu from Pixabay

Biotechnology startup research vs. quality control, how are the two different? Which one is more suitable for you? How do you get started in both? Tune in to learn more from Darren! Intro/Outro music: Music by minwbu from Pixabay

New series: Lit-Update Meet the Expert! where we get to dig deep into papers with the scientist themselves! Our first special guest is Brittany Smith, a PhD Candidate from Duke University, engineer, and marine life expert who is working towards developing technology to benefit marine life and the environment. She will be discussing her latest paper "All-Carbon Thin-Film Transistors Using Water-Only Printing" published in Nano Letters! All-Carbon Thin-Film Transistors Using Water-Only Printing Shiheng Lu, Brittany N. Smith, Hope Meikle, Michael J. Therien, and Aaron D. FranklinNano Letters 2023 23 (6), 2100-2106DOI: 10.1021/acs.nanolett.2c04196 Intro/Outro music: Music by ⁠minwbu⁠ from ⁠Pixabay

Plastics plastics plastics...when they break down into nanoplastics in the ocean, can they transport cancerous polycyclic hydrocarbons to our body? Reference: Erik B. Schiferle, Wenxu Ge, and Björn M. ReinhardACS Nano 2023 17 (6), 5773-5784DOI: 10.1021/acsnano.2c12224 Intro/Outro music: Music by minwbu from Pixabay

We are talking about the weird and wonderful water today and it's amazing new property involving water vapours at ice cold temperatures!! References:  https://www.nature.com/articles/s41586-023-05749-7  https://www.sun.ac.za/english/Lists/news/DispForm.aspx?ID=9860 

Mimicking nanopore transport using nanopore quartz tube to understand protein-protein interactions! Reference: Nanopore Detection Using Supercharged Polypeptide Molecular Carriers Xiaoyi Wang, Tina-Marie Thomas, Ren Ren, Yu Zhou, Peng Zhang, Jingjing Li, Shenglin Cai, Kai Liu, Aleksandar P. Ivanov, Andreas Herrmann, and Joshua B. Edel Journal of the American Chemical Society 2023 145 (11), 6371-6382 DOI: 10.1021/jacs.2c13465 Intro/Outro music: Music by minwbu from Pixabay

It's like three nanotech things all in one! Fascinating research geared towards nano cancer therapeutics References:  Enhanced Nanobubble Formation: Gold Nanoparticle Conjugation to Qβ Virus-like Particles Perouza Parsamian, Yaning Liu, Chen Xie, Zhuo Chen, Peiyuan Kang, Yalini H. Wijesundara, Noora M. Al-Kharji, Ryanne Nicole Ehrman, Orikeda Trashi, Jaona Randrianalisoa, Xiangyu Zhu, Matthew D’Souza, Lucas Anderson Wilson, Moon J. Kim, Zhenpeng Qin, and Jeremiah J. Gassensmith ACS Nano Article ASAP

Amazing work where imine condensation reactions lead up to building molecular nanotube enantiomers using something known as Covalent Organic Pillars COP! References:  Tian, Y., Guo, Y., Dong, X. et al. Synthesis of covalent organic pillars as molecular nanotubes with precise length, diameter and chirality. Nat. Synth (2023). Making molecular nanotubes by cross-linking stackable rings. Nat. Synth (2023).

We previous learned about how nanotech can help advance AI. Now, let's learn about how AI helps scientists to discover new morphologies of directed self-assembled copolymers! References: G. S. Doerk et al., Autonomous discovery of emergent morphologies in directed self-assembly of block copolymer blends. Science Advances. 9, eadd3687 . Intro/Outro music: Music by minwbu from Pixabay

In this lit update we don't really talk about the paper in detail but we had a lot of fun discussing on how relevant or not nanotech is to the ai and language model space. Check it out! References:  Finocchio, Giovanni, et al. "Roadmap for Unconventional Computing with Nanotechnology." arXiv preprint arXiv:2301.06727 (2023). https://arxiv.org/abs/2301.06727 Gongora, Aldair E., et al. "Autonomous experimentation in nanotechnology." Intelligent Nanotechnology. Elsevier, 2023. 331-360.https://www.sciencedirect.com/science/article/pii/B9780323857963000123 Direct laser writing of copper and copper oxide structures on plastic substrates for memristor devices J Jones, MR Snowdon, S Rathod, P Peng - Flexible and Printed Electronics, 2023. https://iopscience.iop.org/article/10.1088/2058-8585/acb0df/meta Intro/Outro music: Music by minwbu from Pixabay

First episode of 2023! Let's start with reflecting on the funny mistakes we made in our early years and what we would like to improve on! Intro/Outro music: Music by minwbu from Pixabay

Last episode of 2022! We have come a long way since we first started and accomplished quite a bit this year. Tune in to the recap of 2022, what we wished we could have covered, and what we have coming up in 2023! Intro/Outro music: Music by minwbu from Pixabay

Interested in pursuing an academic career in North America? And simultaneously sharing all the fun of science online? Tune in to this nanolife interview with Prof. Ben Meekins, the mastermind behind OpenSciencePresentations! Intro/Outro music: Music by minwbu from Pixabay

Incoming lit update! Check out new research that shows nanocages made from DNA are able to capture a wide range of viruses! References:  Broad-Spectrum Virus Trapping with Heparan Sulfate-Modified DNA Origami Shells so fresh no official journal page, etc.  https://cen.acs.org/articles/100/i41/DNA-nanoshells-trap-broad-spectrum.html  Intro/Outro music: Music by minwbu from Pixabay

Atoms, they're everywhere! They're the building blocks of everything but you can't see them with your naked eye, now you can!  Sumaiya, S. A.; Liu, J.; Baykara, M. Z. True Atomic-Resolution Surface Imaging and Manipulation under Ambient Conditions via Conductive Atomic Force Microscopy. ACS Nano 2022. Intro/Outro music: Music by minwbu from Pixabay

Have you heard of CRISPR, the ground breaking gene editing technology? The one that got Emmanuelle Charpentier and Jennifer A. Doudna the Nobel Prize in Chemistry in 2020? This technology was repurposed by researchers from Fudan University to detect cell free DNA! Tune in to learn more! References: Yang, B.; Kong, J.; Fang, X. Programmable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA. Nat Commun 2022, 13, 1-16. Xue, C.; Greene, E. C. DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing. Trends in Genetics 2021, 37, 639-656. Young, L. S.; Yap, L. F.; Murray, P. G. Epstein-Barr virus: more than 50 years old and still providing surprises. Nat Rev Cancer 2016, 16, 789-802. Intro/Outro music: Music by minwbu from Pixabay

Have you heard of CRISPR, the ground breaking gene editing technology? The one that got Emmanuelle Charpentier and Jennifer A. Doudna the Nobel Prize in Chemistry in 2020? This technology was repurposed by researchers from Fudan University to detect cell free DNA! Tune in to learn more!

Fun lit update on Monika's favorite topic haha!! References https://www.nature.com/articles/s41928-022-00798-8#Sec5 https://www.nist.gov/news-events/news/2022/07/leading-experts-suggest-guidelines-assessing-emerging-transistor

Breast and ovarian cancer are some of the most common cancer for females worldwide. As cancer treatment technology continue to advance, scientists in Israel learned that the physiological processes during the different menstruation phases can affect the efficiency of breast and ovarian cancer treatment!  Reference: Poley, M.; Mora-Raimundo, P.; Shammai, Y.; Kaduri, M.; Koren, L.; Adir, O.; Shklover, J.; Shainsky-Roitman, J.; Ramishetti, S.; Man, F.; de Rosales, Rafael T. M.; Zinger, A.; Peer, D.; Ben-Aharon, I.; Schroeder, A. Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility. ACS Nano 2022, 16, 5246-5257. Intro/Outro music: Music by minwbu from Pixabay

Did you know that the physiological processes during the different menstruation phases can affect the efficiency of breast and ovarian cancer treatment? Tune in to learn how scientist in Israel learned about this!

Today we will be talking about safety in nanoscience and technology labs!!!  Reference: https://www.nature.com/articles/s41557-019-0375-x https://www.labsafety.org/lab-safety-terrifying-statistics https://cen.acs.org/safety/lab-safety/10-years-Sheri-Sangjis-death/97/i1 https://www.chemistryworld.com/podcasts/tert-butyl-lithium-or-t-buli/3007986.article

We conclude the end of Season 1 with a special interview episode with soon-to-be Dr. Simone Pengue, who is pursuing his PhD in biophysics and an avid science communicator. This passion led him to be the Grand Prize winner of the Prix Media Newcomer 2021 for the FORGOTTEN DATA: the Leftovers of Science documentary. He will share his experiences as a science journalist while being a PhD candidate at the University of Basel as well as decoding scientific phenomenon in literary arts.  Below are the links to some of his work! Forgotten Data Documentary: trailer and full movie Dante’s Divine Comedy and quantum mechanics (main manuscript in Italian and abstract in English) Background of his PhD Project: A comprehensive review on the physics of nuclear pore complex   Fluorescence Correlation Spectroscopy  Music by: Intro/Outro - minwbu from Pixabay Background - JuliusH from Pixabay

In his spare time, Simone enjoys finding parallels between literary arts work and scientific phenomenon. It's a real life scientific mystery adventure! 

Data classification, organization, and utilization is a pretty dry topic but Simone successfully made an engaging documentary about it! What made him explore this topic in the first place?

Today we will be discussing superhydrophobics coatings using nanofluids, and what is special about this research is that that is comes from easily accessible materials such as silica! References: https://www.azonano.com/news.aspx?newsID=39211 Esmaeilzadeh, P. et al. (2022). Tuning the Wetting Properties of SiO2-Based Nanofluids to Create Durable Surfaces with Special Wettability for Self-Cleaning, Anti-Fouling, and Oil–Water Separation. Industrial & Engineering Chemistry Research. 

Many researchers now are working on miniaturizing and simplifying laboratory processes so that they can be easily used in places such as bed-side hospitals, pharmacies, and ambulances. In this lit update, researchers from UC Davis developed a sensitive nanofiber based immunoassay patch! Tune in to learn more! Reference: Cunyi Zhao, Bofeng Pan, Minyuan Wang, Yang Si, Ameer Y Taha, Gangyu Liu, Tingrui Pan, and Gang Sun. ACS Sensors 2022 7 (5), 1458-1466. DOI: 10.1021/acssensors.2c00208 Intro/Outro music: Music by minwbu from Pixabay

Tune in to this episode to learn more about how researchers simplify and miniaturize laboratory techniques to be used outside the lab!

In this week's lit update, we are discussing the recently discovered "Ferroelectric Nematic Liquid Crystals" and in this work, the researchers have uncovered ways for types of these chiral liquid crystals to change colors with the use of an electric field! Neat!

In today's lit update, we are discussing the recently discovered "Ferroelectric Nematic Liquid Crystals" and in this work, the researchers have uncovered ways for types of these chiral liquid crystals to change colors with the use of an electric field! Neat!  References:  Feng, C., Saha, R., Korblova, E.,  Walba, D., Sprunt, S. N., & Jákli, A. (2021). Electrically Tunable  Reflection Color of Chiral Ferroelectric Nematic Liquid Crystals. Advanced Optical Materials, 9(22), 2101230. Lavrentovich, O. D. (2020). Ferroelectric nematic liquid crystal, a century in waiting. Proceedings of the National Academy of Sciences, 117(26), 14629-14631. Intro/Outro music: Music by minwbu from Pixabay

Did you know that cooking with oil lead to thin oil film deposits on indoor surfaces? These oily deposits can attract water, which can cause bacterial growth and chemical reactions! Tune in to learn what scientists from University of San Diego and University of Texas learned about how the chemical composition of the oil deposits affect how water films form on glass! Reference: Victor W. Or, Michael R. Alves, Michael Wade, Sarah Schwab, Richard L. Corsi, and Vicki H. Grassian Environmental Science & Technology 2022 56 (3), 1594-1604 DOI: 10.1021/acs.est.1c06260 Intro/Outro music: Music by minwbu from Pixabay

Did you know that cooking with oil lead to thin oil film deposits on indoor surfaces? These oily deposits can attract water, which can cause bacterial growth and chemical reactions! Tune in to the upcoming episode to learn what scientists from University of San Diego and University of Texas learned about how the chemical composition of the oil deposits affect how water films form on glass!

Excessive bleeding during surgery or trauma must be stopped immediately before it becomes deadly. In this lit update, scientists from Nankai University developed a chitosan, derived from shrimp shells, microchannelled sponge-like hemostats using 3D printing that can stop bleeding within 2 minutes! Reference: Du, X., Wu, L., Yan, H. et al. Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing. Nat Commun 12, 4733 (2021).  Intro/Outro music: Music by minwbu from Pixabay

Tune in to the new episode to learn how shrimp shells can be used to prevent excessive bleeding!

In today's awesome lit update, we talk about lithium-air-breathing batteries! (LABs!) Wait, what?! Now these lithium air-breathing batteries, often known as LABs or LOBs as in Lithium-Oxygen Batteries don’t actually have lungs! Their operation is based on the metal-air interface to function. Tune in to learn more and check out the full research here: Kim, Hyun‐Soo, Boran Kim, Hyunyoung Park, Jongsoon Kim, and Won‐Hee Ryu. Auto‐Oxygenated Porphyrin‐Derived Redox Mediators for High‐Performance Lithium Air‐Breathing Batteries. Advanced Energy Materials (2022): 2103527.

Teaser for our upcoming episode discussing new research on lithium - air batteries! Kim, Hyun‐Soo, Boran Kim, Hyunyoung Park, Jongsoon Kim, and Won‐Hee Ryu. "Auto‐Oxygenated Porphyrin‐Derived Redox Mediators for High‐Performance Lithium Air‐Breathing Batteries." Advanced Energy Materials (2022): 2103527.

We constantly hear that personalized medicine is the medicine of the future but when will this become a reality? Researchers in this field are constantly making progress and one of the most recent developments is from researchers in Israel and China who made wearable microneedle sensors for continuous sodium monitoring!  Reference: Zheng, Y. et al. A Wearable Microneedle-Based Extended Gate Transistor for Real-Time Detection of Sodium in Interstitial Fluids. Advanced Materials 34, 2108607 (2022). Intro/Outro music: Music by minwbu from Pixabay

We constantly hear that personalized medicine is the medicine of the future but when will this become a reality? Researchers in this field are constantly making progress and one of the most recent developments is from researchers in Israel and China who made wearable microneedle sensors for continuous sodium monitoring!