The Murmur Pod

PODCAST · health

The Murmur Pod

The Murmur Pod is hosted by Dr. Aidan Raney III and Dr. Joe Walsh. Specializing in interventional cardiology, they explore happenings in the cardiology and medical communities, discuss interesting cases, review new technology, and more.This podcast is presented first in the MurmurMD App! Work in the cath lab? Reach out to join the private community there!

  1. 46

    When PCI Gets Dangerous: How LV Support Changes High-Risk Cases

    High-risk PCI isn’t just about technique — it’s about protecting the patient while you fix the artery.In this MurmurMD discussion, Dr. Chris Brown and Dr. Yousif Ahmad walk through the role of left ventricular (LV) support in complex PCI, focusing on when to escalate, how to think about hemodynamics, and why support can change the entire strategy.Key insights from the discussion include:• Identifying patients who qualify as high-risk PCI• Recognizing when hemodynamics may deteriorate during intervention• Deciding when to use LV support devices• How support changes procedural planning and execution• Balancing complete revascularization with patient stability• Real-time decision-making during complex cases• Lessons learned from managing high-risk coronary interventionsThis discussion highlights a critical shift in mindset:in high-risk PCI, success depends as much on support strategy as it does on technical skill.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – What defines high-risk PCI 01:00 – Hemodynamic risk and patient selection 02:30 – When to escalate to LV support 04:00 – How support changes PCI strategy 06:00 – Procedural decision-making under support 07:30 – Outcomes and key takeaways#HighRiskPCI #LVSupport #ComplexPCI #MechanicalCirculatorySupport #InterventionalCardiology #CathLab #MurmurMD

  2. 45

    Champion AF Explained: Can LAA Closure Beat DOACs? Ft. Dr. Saibal Kar and Dr. Tom Waggoner

    The Champion AF trial is one of the most important studies in structural heart — directly comparing left atrial appendage closure (LAAC) to DOAC therapy in patients with atrial fibrillation.In this MurmurMD discussion, Dr. Saibal Kar and Dr. Thomas Waggoner break down the Champion AF data, focusing on what the results actually mean for clinical practice and how they may shift long-term management strategies.Key themes from the transcript include:• The rationale behind comparing LAAC to DOAC therapy• Trial design and patient population• Key outcomes and how to interpret them• Safety and efficacy considerations• Where LAAC fits in the treatment algorithm today• How these results may impact future guidelines and patient selectionThis discussion offers a practical, real-world interpretation of a pivotal trial — and what it means for stroke prevention in atrial fibrillation moving forward.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Overview of Champion AF and why it matters 01:00 – Trial design and patient selection 03:00 – Key outcomes and results interpretation 05:30 – Safety and procedural considerations 07:00 – LAAC vs DOAC: how to think about it clinically 08:30 – What this means for practice and future direction#ChampionAF #LAAClosure #AtrialFibrillation #StrokePrevention #StructuralHeart #Watchman #InterventionalCardiology #MurmurMD

  3. 44

    Stent Thrombosis Management: IVUS-Guided Strategy and When to Use DCB

    Stent thrombosis is one of the most high-stakes complications in PCI — and getting the mechanism right is everything.In this MurmurMD case discussion, Dr. Nyal Borges and Dr. Joe Walsh walk through a real-world case of stent thrombosis, focusing on how intravascular imaging (IVUS) guides diagnosis and how drug-coated balloons (DCB) fit into the treatment strategy.Key discussion points from the transcript include:• Identifying the underlying cause of stent thrombosis• Why angiography alone is insufficient in these cases• Using IVUS to detect under-expansion, malapposition, or mechanical issues• Stepwise management of thrombus and lesion preparation• When additional stenting may worsen outcomes• The role of DCB in avoiding further metal layers• Optimizing vessel expansion before definitive therapy• Real-time decision making during a complex thrombotic caseThis discussion highlights a critical principle:stent thrombosis is not just treated — it is diagnosed and corrected with imaging.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Case introduction: stent thrombosis presentation 00:40 – Initial angiographic findings 01:20 – Why imaging is critical in stent thrombosis 02:10 – IVUS assessment and identifying the mechanism 03:10 – Lesion preparation and thrombus management 04:10 – Deciding against additional stenting 05:00 – Role of DCB in treatment strategy 05:50 – Final optimization and imaging confirmation 06:30 – Key lessons for managing stent thrombosis#StentThrombosis #IVUS #DCB #ComplexPCI #InterventionalCardiology #CathLab #CoronaryIntervention #MurmurMD

  4. 43

    Case Discussion- TAVR Valve Implantation Techniques: Positioning, Deployment and Procedural Strategy

    Successful TAVR depends on precise positioning, controlled deployment, and a clear procedural strategy.In this MurmurMD discussion, Dr. Nathan Frogge and Dr. Matthew Summers review key TAVR valve implantation techniques (highlighting Cusp Overlap), focusing on how to optimize positioning, manage deployment, and improve procedural outcomes.Key discussion points from the transcript include:• Planning valve positioning before deployment• Understanding anatomy and fluoroscopic views• Controlling implant depth during deployment• Techniques for stable and controlled valve release• Adjusting positioning during the procedure• Managing procedural challenges during implantation• Optimizing final valve position and function• Lessons learned from real-world TAVR experienceThis discussion provides practical insights into how experienced operators approach valve implantation to achieve consistent and safe outcomes.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Introduction to TAVR implantation techniques 00:40 – Pre-procedural planning and anatomy 01:30 – Fluoroscopic views and positioning 02:20 – Valve deployment strategy 03:10 – Controlling implant depth 04:00 – Managing positioning adjustments 04:50 – Handling procedural challenges 05:40 – Final valve position and optimization 06:30 – Key takeaways from implantation techniques#TAVR #StructuralHeart #ValveImplantation #AorticStenosis #HeartTeam #InterventionalCardiology #CathLab #MurmurMD

  5. 42

    Two Layers of Stent in the Ostial RCA: Strategy, Imaging, and PCI Decision Making

    Ostial RCA disease can be one of the most unforgiving lesions in coronary intervention — especially when multiple layers of stent are already present.In this MurmurMD case discussion, Dr. Nyal Borges and Dr. Joe Walsh review a challenging PCI involving two layers of stent at the ostial right coronary artery, focusing on how imaging and careful technique guide treatment decisions.The discussion walks through the key procedural considerations in managing complex ostial stent anatomy, including:• Evaluating restenosis and mechanical issues in previously stented segments• Understanding the challenges of ostial RCA stent positioning• Using intravascular imaging to assess stent expansion and vessel anatomy• Managing overlapping or layered stent architecture• Planning intervention when additional metal may worsen long-term outcomes• Balancing lesion preparation with procedural risk• Recognizing technical pitfalls unique to ostial coronary diseaseThis case provides practical insights into how experienced operators approach complex ostial PCI with prior stent layers.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Case introduction: ostial RCA with prior stents 00:40 – Angiographic review and lesion assessment 01:30 – Understanding the challenge of two stent layers 02:20 – Imaging evaluation and vessel sizing 03:20 – Strategy discussion for treating ostial restenosis 04:20 – Device and technique considerations 05:10 – Procedural outcome and imaging review 06:00 – Lessons from managing layered ostial stents#OstialRCA #ComplexPCI #IVUS #InStentRestenosis #InterventionalCardiology #CathLab #MurmurMD

  6. 41

    Cusp Overlap Technique for SEV: Deep Dive on Controlling Implant Depth and Conduction Risk with Dr. Frogge and Dr. Summers

    The cusp overlap technique has become an important strategy during TAVR with self-expanding valves to improve implant depth control and reduce conduction disturbances.In this MurmurMD discussion, Dr. Nathan Frogge and Dr. Matthew Summers walk through how and why they use the cusp overlap technique, focusing on fluoroscopic positioning, implant depth control, and procedural workflow adjustments.Key discussion points from the transcript include:• Why implant depth is critical in self-expanding TAVR valves• The relationship between implant depth and conduction system injury• How the cusp overlap view improves visualization of the non-coronary cusp• Fluoroscopic projection setup and imaging angles• Deployment technique and depth control strategies• Procedural workflow when using cusp overlap routinely• Lessons learned from operators using cusp overlap in practiceThis discussion provides practical insight into how cusp overlap helps operators control valve implantation and reduce conduction complications during TAVR.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Introduction to cusp overlap technique in TAVR 00:40 – Why implant depth matters for self-expanding valves 01:30 – Conduction disturbances and valve depth 02:20 – Setting up the cusp overlap fluoroscopic view 03:10 – Deployment technique and depth control 04:00 – Workflow adjustments using cusp overlap 05:00 – Imaging and positioning tips 06:00 – Lessons learned and key takeaways#TAVR #StructuralHeart #CuspOverlap #SelfExpandingValve #ConductionSystem #InterventionalCardiology #CathLab #MurmurMD

  7. 40

    TAVR Valve Durability: Long-Term Outcomes, Unknowns, and Clinical Decision Making with Dr. Curtiss Stinis and Dr. Andrei Pop

    As TAVR expands into younger and lower-risk populations, valve durability has become a central question in structural heart care.In this MurmurMD discussion, Dr. Curtiss Stinis and Dr. Andrei Pop review current understanding of TAVR valve durability, focusing on how clinicians interpret available data and apply it to real-world patient decisions.The conversation highlights key themes from the transcript, including:• How durability data for TAVR has evolved over time• The challenges of comparing surgical and transcatheter valve longevity• Structural valve degeneration and how it is defined and measured• The role of patient age and lifetime management strategy• Imaging and follow-up approaches to monitor valve performance• Valve-in-valve considerations as transcatheter valves age• The importance of long-term data as TAVR indications expandThis discussion provides a practical perspective on how clinicians are thinking about durability today while planning for the future of valve therapy.Chapters:00:00 – Introduction to TAVR durability discussion 00:40 – Why durability matters more in lower-risk patients 01:30 – Current data on TAVR valve performance 02:30 – Defining structural valve degeneration 03:20 – Surgical vs transcatheter durability considerations 04:10 – Imaging and long-term follow-up 05:10 – Valve-in-valve strategy and future planning 06:00 – Patient selection and lifetime valve management 07:00 – Key takeaways from the discussion🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#TAVR #StructuralHeart #ValveDurability #AorticStenosis #HeartTeam #InterventionalCardiology #MurmurMD

  8. 39

    When a Patient is told they have no options: Complex Coronary Intervention Case with Dr. Brown and Dr. Rothstein

    Complex coronary PCI often requires careful planning, imaging, and stepwise escalation of technique to achieve a safe and durable result.In this MurmurMD case discussion, Dr. Chris Brown and Dr. Eric Rothstein review a challenging coronary intervention and walk through the decision-making process used throughout the procedure.The conversation highlights key aspects of managing difficult coronary anatomy, including:• Assessing lesion complexity and procedural risk• Planning the intervention strategy before device escalation• Using imaging and angiography to guide treatment decisions• Selecting appropriate wires, balloons, and stent strategy• Managing resistance during device delivery• Recognizing when to modify the approach mid-procedure• Achieving optimal stent expansion and final procedural resultThis case review provides practical insight into how experienced operators approach complex coronary interventions in the cath lab.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Introduction to the coronary intervention case 00:40 – Patient presentation and angiographic findings 01:30 – Assessing lesion complexity and procedural planning 02:20 – Initial device strategy and lesion preparation 03:20 – Device escalation and procedural adjustments 04:20 – Stent placement and expansion strategy 05:10 – Imaging review and final optimization 06:00 – Final result and procedural takeaways#ComplexPCI #CoronaryIntervention #InterventionalCardiology #CathLab #CoronaryDisease #PCI #MurmurMD

  9. 38

    LAVA ECMO in Structural Heart Procedures: Hemodynamic Support Strategy Explained with Dr. Giustino and Dr. Pop

    Structural heart interventions increasingly involve patients with severe ventricular dysfunction, valvular shock, or limited hemodynamic reserve. In these cases, maintaining stability throughout the procedure can be the biggest challenge.In this MurmurMD discussion and case review, Dr. Gennaro Giustino and Dr. Andrei Pop review how LAVA ECMO (Left Atrial Veno-Arterial ECMO) can be used to support patients undergoing complex structural heart interventions.The conversation walks through practical considerations around the use of LAVA ECMO, including:• Why traditional support strategies can be insufficient during certain structural interventions• How LAVA ECMO provides effective hemodynamic support in unstable patients• The physiologic advantages of left atrial drainage• Procedural setup and access considerations• How ECMO support can stabilize patients during high-risk valve procedures• Integrating mechanical circulatory support into structural heart workflows• Lessons learned from real-world cases using LAVA ECMOThis discussion highlights how advanced support strategies are becoming an important tool for managing high-risk structural heart patients.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Introduction to LAVA ECMO support 00:40 – Why hemodynamic support is needed in structural procedures 01:30 – Physiologic rationale for left atrial drainage 02:20 – How LAVA ECMO differs from traditional ECMO support 03:10 – Procedural setup and access strategy 04:10 – Use of ECMO during structural interventions 05:10 – Managing hemodynamics throughout the procedure 06:00 – Clinical outcomes and lessons learned 06:50 – Key takeaways for structural heart teams#ECMO #LAVAECMO #StructuralHeart #MechanicalCirculatorySupport #CardiogenicShock #InterventionalCardiology #CathLab #MurmurMD

  10. 37

    Cardiogenic Shock Case Discussion: Recognizing Shock Physiology and Escalating Support with Dr. Walsh and Dr. Mcneely

    Cardiogenic shock cases demand rapid recognition, structured thinking, and decisive escalation of support.In this MurmurMD case discussion, operators review a complex patient presentation with cardiogenic shock and walk through the clinical reasoning that guided management decisions.The conversation focuses on practical decision-making during shock physiology, including:• Recognizing early signs of cardiogenic shock• Interpreting hemodynamics and clinical presentation• Understanding when medical therapy is insufficient• Deciding when to escalate mechanical circulatory support• Balancing revascularization strategy with hemodynamic stability• Team communication during rapidly evolving cases• Learning from real-world shock managementThis case discussion provides a practical look at how experienced operators approach cardiogenic shock in the cath lab and critical care setting.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Case introduction and patient presentation 00:40 – Recognizing cardiogenic shock physiology 01:20 – Initial management and stabilization strategy 02:10 – Hemodynamic interpretation and decision points 03:10 – Escalating support and procedural considerations 04:00 – Revascularization strategy during shock 05:00 – Clinical course and procedural outcome 06:00 – Key lessons from the case discussion#CardiogenicShock #MechanicalCirculatorySupport #InterventionalCardiology #CriticalCareCardiology #CathLab #MurmurMD

  11. 36

    Iliac CTO Case Series: Radial R2P, Externalization, IVUS, and Covered Stent Strategy with Dr. Mohan and Dr. Sameh Sayfo

    Iliac CTO interventions follow patterns — but recognizing them in real time is what separates a difficult case from a controlled one.In this MurmurMD case discussion, Dr. Jay Mohan and Dr. Sameh Sayfo walk through two iliac CTO interventions, highlighting practical lessons in access strategy, crossing techniques, IVUS guidance, and covered stent deployment.Key concepts discussed directly from the transcript include:• Why ABI can appear normal despite severe inflow disease• Using waveform analysis and CTA to guide planning• When femoral access fails — and why radial R2P changes the game• Recognizing the true stump and avoiding false lumen escalation• Externalizing the wire and advancing destination-style sheaths• IVUS (014 vs 018) for accurate vessel sizing• Bilateral kissing covered stents in complex aorto-iliac anatomy• Managing aneurysmal segments and knowing when to consider EVAR• Using a misplaced wire as a roadmap instead of removing it too early• Covered stent strategy to manage large dissections safelyTwo real-world cases. One disciplined algorithm. A practical discussion for anyone treating complex iliac disease.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Introduction: Recognizing iliac CTO patterns 00:30 – Case 1 overview and waveform clues 01:10 – CTA review and identifying the true stump 01:40 – Femoral access failure → switching to radial R2P 02:20 – Crossing strategy and wire externalization 03:00 – IVUS sizing and covered stent selection 03:40 – Bilateral kissing stents and aneurysm considerations 04:20 – Case 2 overview: prior stent and new CTO 05:00 – False lumen wire as a landmark 05:40 – Radial crossing and externalization 06:10 – Managing dissection with covered stents 06:40 – Final results and key takeaways#PeripheralIntervention #IliacCTO #IVUS #CoveredStents #Endovascular #R2P #PeripheralArteryDisease #MurmurMD

  12. 35

    TAVR Explant: When, Why, and How to Safely Remove a Transcatheter Valve with Dr. Clinton Kemp and Dr. Matt Summers

    As TAVR expands into younger and lower-risk populations, TAVR explant is no longer a theoretical problem — it’s a real and growing clinical scenario.In this MurmurMD discussion, Dr. Clinton Kemp and Dr. Matt Summers walk through the indications, technical challenges, and operative considerations involved in TAVR explant, emphasizing why early planning and multidisciplinary alignment are critical for patient outcomes.Topics covered directly from the transcript include:• Common indications for TAVR explant, including endocarditis, valve failure, and patient–prosthesis mismatch• Why TAVR explant is fundamentally different from native SAVR• Timing considerations: early vs late explant• How valve type and frame design affect surgical strategy• Annular, coronary, and aortic root risks during explant• Managing adhesions and embolization• When partial explant or valve-in-valve may be preferable• The importance of preoperative imaging and surgical planning• Why TAVR explant requires true heart team collaboration• How explant considerations should influence initial TAVR valve selectionA must-watch discussion for structural heart teams navigating the long-term implications of TAVR therapy.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Why TAVR explant is becoming more common 01:00 – Indications that lead to explant consideration 02:00 – Early vs late TAVR explant: what changes technically 03:00 – Valve design and frame considerations 04:00 – Surgical risks to the annulus, coronaries, and root 05:00 – Managing endothelialization and adhesions 06:00 – When valve-in-valve is not the right answer 07:00 – Imaging and preoperative planning essentials 08:00 – Heart team decision-making for explant cases 09:00 – How explant risk should influence initial TAVR choice 10:00 – Key takeaways for structural programs#TAVR #StructuralHeart #ValveExplant #CardiacSurgery #HeartTeam #AorticValve #InterventionalCardiology #MurmurMD

  13. 34

    Iliac CTO Masterclass: Access, IVUS, Re-Entry, IVL, and Stent Strategy with Dr. Jay Mohan and Dr. Sameh Sayfo

    Iliac CTOs are among the highest-risk, highest-reward procedures in peripheral intervention. In this MurmurMD session, Dr. Jay Mohan joins Dr. Sameh Sayfo to break down their full approach — from diagnosis and CTA planning to crossing strategies, re-entry methods, IVUS, vessel prep, and stent selection.This case-driven conversation is packed with pearls on how to handle complex iliac occlusions safely and predictably.What you’ll learn from this transcript-based discussion:• Why PVR and waveform analysis matter more than ABI alone• CTA essentials: calcium burden, aorto-iliac disease, access planning• Jay’s preferred dual-access setup (radial + ipsilateral femoral)• When to start anti-grade vs retrograde — and how to choose the correct cap• Safe knuckling with microcatheter support through the CTO• How to externalize the wire and complete the case through femoral access• Why “every iliac should be IVUS”• IVL in the iliac system: M5+, L6, Javelin, and how vessel size determines device choice• Covered vs uncovered stents (VBX, ICAST, Lifestream, Visi-Pro)• Why balloon-expandable covered stents dominate TASC C/D and CTO lesions• When to use kissing stents and when to avoid self-expanding at the common iliac ostium• Rescue toolkit: covered stents, bright-tip sheaths, alternative access, balloon tamponade• Why Pioneer re-entry is less common now — and how R2P changed the gameA must-watch for operators who want to sharpen their iliac CTO algorithm and device selection.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Why iliac CTOs are high-risk, high-reward lesions 01:00 – Symptoms, ABI/PVR, waveform interpretation 02:00 – CTA planning: calcium, inflow disease, access strategy 03:00 – Choosing access: radial + ipsilateral femoral 04:00 – Anti-grade vs retrograde crossing strategy 05:00 – Knuckling technique and microcatheter support 06:00 – Re-entry options: R2P vs Pioneer 07:00 – IVUS: why “every iliac should be IVUS” 08:00 – Vessel prep: M5+, L6, Javelin, and when each matters 09:00 – Stent selection: covered vs uncovered, ostial precision 10:00 – Kissing stents and hybrid approaches 11:00 – Rescue toolkit: perforation, sheath size, balloon tamponade 12:00 – Final pearls for early operators#PeripheralIntervention #IliacCTO #IVL #IVUS #Endovascular #ComplexPCI #PeripheralArteryDisease #MurmurMD #VBX #ICAST #R2P #CoveredStents

  14. 33

    BiPella in Acute MI Shock: When Biventricular Unloading Beats Inotropes

    Not all cardiogenic shock after acute MI is left-sided — and treating it like it is can be fatal.In this MurmurMD case discussion, Dr. Chris Brown walks through a young patient with acute MI, progressive shock, and severe right ventricular failure, highlighting how early recognition and biventricular mechanical support (Bipella physiology) stabilized the patient when inotropes and balloon support failed.This transcript-based conversation focuses on real-time decision-making, including:• Differentiating acute occlusion from chronic disease in an MI presentation• Why rising troponins without washout suggested ongoing ischemia• Recognizing RV failure as the primary shock driver• Why balloon pump and escalating inotropes worsened physiology• Early RV unloading with RP support as the first step toward BiPella• Hemodynamic clues that mandated adding LV unloading• Why RV support should precede LV support in evolving BiPella shock• PCI strategy once full biventricular support is established• Renal recovery after unloading both ventricles• Using BiPella as a bridge to recovery, LVAD, or transplant decision-making• Why unloading injured myocardium outperforms pharmacologic stimulationA clear, real-world example of BiPella physiology saving a failing heart when revascularization alone isn’t enough.Chapters:00:00 – Acute MI with shock: LV vs RV failure dilemma 01:00 – Troponin trends and evidence of ongoing ischemia 02:00 – Recognizing RV failure as the dominant problem 03:00 – Why balloon pump and inotropes failed 04:00 – Decision to unload the RV first 05:00 – Transitioning toward BiPella physiology 06:00 – Hemodynamics that triggered LV unloading 07:00 – PCI strategy under biventricular support 08:00 – Renal recovery and early organ response 09:00 – Weaning strategy and support sequencing 10:00 – BiPella as bridge to recovery vs advanced therapies 11:00 – Final lessons: unload, don’t overstimulate🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#BiPella #BiventricularSupport #CardiogenicShock #AcuteMI #MechanicalCirculatorySupport #Impella #CriticalCareCardiology #InterventionalCardiology #MurmurMD

  15. 32

    How to Build a High-Functioning Valve Clinic: Structure, Workflow, and Real-World Lessons

    A successful valve program isn’t built in the cath lab alone — it’s built in the clinic, the workflow, and the team structure behind the scenes.In this MurmurMD discussion, Dr. Andrei Pop and Caitlin O'Callaghan Reen, CNP, FACC walk through how they’ve structured and scaled a high-functioning valve clinic, covering everything from referrals and imaging to staffing models and follow-up.The conversation breaks down what actually works in day-to-day practice, including:• Why valve clinics must be process-driven, not physician-dependent• How referral pathways determine procedural volume and case quality• Organizing clinic flow around echo, CT, and multidisciplinary review• The role of APPs, nurses, coordinators, and administrators• Avoiding bottlenecks between clinic, imaging, and procedure scheduling• Managing TAVR, TEER, and surgical referrals in a single ecosystem• Pre-visit planning to reduce wasted clinic visits• Post-procedure follow-up models that prevent patients from being lost• How data tracking and communication improve outcomes and efficiency• Common mistakes programs make when scaling too quicklyA practical guide for anyone building, optimizing, or expanding a structural heart valve clinic.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-stor...📺 Follow us on YouTube: / @murmurmd Chapters:00:00 – Why valve clinic structure matters 01:00 – Referral pathways and patient intake 02:00 – Clinic workflow and visit organization 03:00 – Imaging coordination: echo, CT, and review 04:00 – Multidisciplinary decision-making 05:00 – Staffing models and role definitions 06:00 – APPs and coordinators as the backbone of the clinic 07:00 – Scheduling procedures without bottlenecks 08:00 – Managing multiple valve therapies in one clinic 09:00 – Pre-visit planning to improve efficiency 10:00 – Post-procedure follow-up and continuity of care 11:00 – Tracking outcomes and operational metrics 12:00 – Common pitfalls when scaling a valve program 13:00 – Final lessons for sustainable growth#StructuralHeart #ValveClinic #TAVR #TEER #HeartTeam #HealthcareOperations #Cardiology #ProgramBuilding #MurmurMD

  16. 31

    Watchman TruSteer deep dive & Cases Steering, Coaxiality, and Deployment Efficiency in LAAC

    In this MurmurMD discussion, Dr. Raghava Gollapudi and Dr. Arvin Narula break down how the Watchman TruSteer sheath changes left atrial appendage occlusion (LAAO) workflows — from transeptal access to final device deployment.The conversation focuses on real-world use, and highlights when TruSteer adds value, how it improves coaxiality, and why many operators are moving toward using it routinely.Topics covered in this transcript-based discussion include:• Why earlier Watchman sheaths limited depth and stability• How TruSteer allows four-directional control (superior, inferior, anterior, posterior)• Using the device body and sheath as complementary anchoring mechanisms• Improving coaxial alignment without repeating transeptal puncture• Why TruSteer reduces redeployments and manipulation• Large anterior chicken-wing, flat, and posterior appendage anatomy• Efficiency gains vs cost considerations• Why some operators now use TruSteer in nearly every case• Safety pearls: avoiding steering with the dilator in place• Minimizing air and bubble risk by reducing sheath exchanges• Achieving zero-leak goals in the Watchman FLX eraA practical discussion for operators looking to improve precision, safety, and efficiency in LAAO.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-stor...📺 Follow us on YouTube: / @murmurmd Chapters:00:00 – Introduction to Watchman TruSteer 00:40 – Limitations of earlier Watchman sheaths 01:40 – Four-directional steering and coaxial control 03:00 – Using the sheath vs the device body for positioning 04:10 – Challenging appendage anatomy: chicken-wing and posterior LAA 05:30 – Improving depth without repeating transeptal 06:40 – Efficiency, safety, and air management 08:00 – Cost vs value: when TruSteer adds benefit 09:20 – Zero-leak mindset in the FLX era 10:40 – Safety tips and final takeaways#LAAO #LAAC #Watchman #TruSteer #StructuralHeart #InterventionalCardiology #CathLab #MurmurMD #WatchmanFLX #LeftAtrialAppendage

  17. 30

    Common Femoral Disease Without Surgery? Two High-Risk Cases and Modern Endovascular Strategy with Dr. Sayfo and Dr. Mouawad

    Redo groins, radiation injury, prior infection, and failed bypasses make common femoral artery disease some of the most difficult decisions in vascular care.In this case-based discussion, Dr. Nick Mouawad and Dr. Sameh Sayfo walk through two challenging common femoral artery cases where traditional open surgery carried high risk.Topics covered include:• Managing CFA bifurcation disease after prior radiation and surgical complications• Why the profunda femoris artery must always be protected• Radial-to-peripheral access to avoid hostile groins• Intravascular imaging to guide vessel sizing and therapy• When to use IVL, atherectomy, serration balloons, and DCB• Avoiding stents in the common femoral whenever possible• Multidisciplinary decision-making for durable outcomesA practical, honest discussion focused on patient selection, technique, and long-term durability in modern peripheral intervention.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters: 00:00 – Case setup and goals of discussion00:45 – Prior pelvic radiation and failed CFA surgery02:05 – Risks of redo open CFA endarterectomy03:10 – Why the profunda femoris must be protected04:20 – Radial access strategy to avoid hostile groins05:05 – IVUS-guided sizing and IVL preparation06:00 – Serration balloons and DCB for CFA disease07:15 – Avoiding stents in the common femoral artery07:55 – Second case: prior fem-fem bypass and claudication09:10 – Crossing strategy and imaging uncertainty10:05 – Orbital atherectomy near bypass anastomosis11:45 – IVUS, gradients, and confirming success12:45 – Durability vs redo surgery discussion14:00 – Multidisciplinary collaboration and MurmurMD#CommonFemoralArtery #PeripheralArteryDisease #IVL #IVUS #Endovascular #VascularSurgery #RedoGroin #RadialToPeripheral #MurmurMD #MultidisciplinaryCare

  18. 29

    Leaflet Modification: Basilica, Shortcut, and the Future of Coronary Protection with Dr. Toby Rogers and Dr. Andrei Pop

    Leaflet modification has rapidly evolved from niche innovation to a cornerstone of lifetime TAVR management.In this discussion, Dr. Toby Rogers joins Dr. Andrei Pop to explore the latest data, device advances, and clinical decision-making behind Basilica, Shortcut, and emerging techniques like Telltale, Unicorn, and leaflet excision.Key topics covered:History of leaflet modification — from LAMPOON to BASILICA and now device-guided proceduresHow Shortcut and Telltale are changing training and accessWhy leaflet modification is still primarily for TAV-in-SAV but expanding to redo-TAVRBalancing risk, complexity, and informed consent for lower-risk patientsRole of CT simulation, FEops, and DASI modeling for lifetime valve planningWhen to err on the side of leaflet modification vs risking coronary obstructionCoronary height and valve-to-coronary distance — why those 2–4mm cutoffs aren’t gospelFuture directions: routine modification, improved washout, and potential HALT reductionAccess routes (carotid, transcaval, axillary) and practical tips for operatorsComparing BASILICA, Shortcut, Unicorn, and Telltale—safety, mechanism, and learning curveWhy new devices need structured trials before widespread useThis is essential viewing for structural heart operators refining TAVR-in-TAVR safety, coronary access strategies, and the future of leaflet modification.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Introduction: The evolution of leaflet modification 00:40 – From LAMPoon to BASILICA: history of electrosurgery 02:00 – Off-label origins and why it mattered 03:00 – Shortcut and Telltale: first commercial systems 05:00 – Who qualifies? High-risk vs lower-risk considerations 06:30 – Lifetime management and early valve planning 08:00 – Simulation tools (3Mensio, FEops, DASI) in valve strategy 09:30 – Challenges in coronary height and valve-to-coronary measurement 12:00 – Surgical perspective: root enlargement and small annuli 13:00 – Rethinking the “risk-based” TAVR vs SAVR decision 15:00 – When to err toward leaflet modification 17:00 – New benefits beyond obstruction: access & flow dynamics 19:00 – Routine modification in the future? 20:00 – Cerebral protection data and operator practices 23:00 – Access routes: transfemoral vs transcarotid approaches 25:00 – Comparing BASILICA, Shortcut, Unicorn & Telltale 28:00 – Risks of balloon-tear methods and lack of validation 30:00 – Data-driven advancement vs anecdotal adoption 31:00 – Future of device design and mitral implications 33:00 – Closing remarks and next frontier: mitral leaflet work#LeafletModification #BASILICA #Shortcut #Telltale #TAVRinTAVR #ValveinValve #StructuralHeart #CoronaryProtection #AorticValve #MurmurMD

  19. 28

    Fixing a Calcified LIMA: Rota, Shockwave, and DCB in a Tortuous Distal LAD with Dr. Arvin Narula and Dr. Joe Walsh

    LIMA interventions are rare, high-risk, and technically unforgiving. In this MurmurMD case session, Dr. Arvin Narula and Dr. Joe Walsh walk through an extremely challenging LIMA-to-LAD lesion involving heavy calcification, tortuosity, failed prior PCI, device entrapment, rotational atherectomy, Shockwave IVL, and management of unexpected graft thrombus.This discussion delivers real-world strategy, troubleshooting, and device thinking you won’t find in textbooks.Key insights from the case:• Why left distal transradial can provide safer LIMA engagement• The moment a Corsair microcatheter is “chewed up” — and why that signals severe calcium• How to decide between more support, downsizing, or plaque modification• When rotational atherectomy is safe in a LIMA graft — and when it’s not• Why starting the burr in the native LAD, not the graft, may reduce risk• How dual preparation (Rota + Shockwave) improves expansion• DCB strategy for distal LAD disease• Managing LIMA thrombus: ACT troubleshooting, lytics, aspiration, and stent “tattooing”• Tricks for keeping thrombus from embolizing distally• How to avoid dissecting the LIMA ostium during exchanges• What to do if ACT remains subtherapeutic despite multiple bolusesThis is an advanced case with invaluable pearls for anyone treating heavily calcified coronaries, bypass graft disease, or LIMA interventions.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Why LIMA interventions are challenging 00:40 – Patient background and LIMA access strategy 01:20 – Tortuosity, calcium, and microcatheter difficulty 02:00 – Deciding to escalate to rotational atherectomy 02:40 – Rota technique and safety considerations in LIMA 03:30 – Adding Shockwave for dual preparation 04:10 – DCB strategy for distal LAD disease 04:50 – Managing sudden LIMA thrombus and low ACT 05:40 – Final result and key takeaways#ComplexPCI #LIMAIntervention #RotationalAtherectomy #ShockwaveIVL #DCB #Atherectomy #CoronaryCalcium #InterventionalCardiology #BypassGraftPCI #CathLab #MurmurMD

  20. 27

    Mastering PASCAL in Complex Mitral Anatomy: Strategy, Technique, and Real-World Lessons: SWAC Nov 25

    Complex mitral valve anatomy continues to challenge even the most experienced TEER operators. In this month's SWAC conference, Dr. Sergio Garcia, Dr. Tom Waggoner, Dr. Mark Bieniarz, and Dr. Aidan Raney walk through how to approach PASCAL therapy in anatomies where leaflet length, clefts, stenosis, and calcification make decision-making difficult.Using multiple real patient examples, they break down:• How PASCAL’s separatable clasps change strategy in short posterior leaflets• When to choose PASCAL vs Pascal Ace based on anatomy• Managing posterior leaflet restriction, clefts, and deep scallop gaps• How clasping technique differs from MitraClip• Imaging keys for procedural success on transesophageal echo• When to attempt independent clasping—and when not to• Avoiding iatrogenic mitral stenosis• What to do when coaptation depth is low or leaflet mobility is asymmetric• Real-world case outcomes, lessons, and clinical pearls from each scenarioA must-watch for operators training in PASCAL or managing anatomies that push TEER beyond standard degenerative or functional mitral regurgitation.Chapters:00:00 – Introduction: Why complex mitral anatomy requires a different strategy 01:00 – Case review overview and PASCAL system fundamentals 01:40 – Leaflet length, calcium, clefts: deciding if TEER is feasible 02:20 – When to choose PASCAL vs Pascal Ace 03:00 – Understanding PASCAL’s independent clasping advantage 03:40 – Case 1: Short posterior leaflet and how to secure a durable grasp 04:20 – Using TEE to confirm leaflet insertion and avoid chordal entanglement 04:50 – Maneuvering around a cleft and choosing the correct landing zone 05:20 – Case 2: Posterior leaflet restriction and reduced mobility 05:50 – Why independent clasping helps unequal coaptation 06:20 – Residual MR strategies: reposition, reclasp, or add a second device 06:50 – Case 3: When coaptation depth is too shallow for a central grasp 07:20 – Recognizing when stenosis risk outweighs TEER benefit 07:45 – Procedural adjustments when leaflet tissue is limited 08:10 – Case 4: Complex functional MR with tenting and asymmetric jets 08:45 – TEE markers for good versus poor grasping zones 09:10 – Post-grasp evaluation: gradients, residual jets, and stability 09:40 – Final thoughts: how PASCAL expands TEER into anatomies once avoided🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#Mitr alValve #TEER #PASCAL #StructuralHeart #TAVR #HeartTeam #EchoGuidedProcedures #InterventionalCardiology #MitralRegurgitation #MurmurMD #SWAC

  21. 26

    Common Femoral Artery Intervention: Surgery vs IVL – Dr. Mouawad & Dr. Sayfo

    The common femoral artery has always been considered a surgical zone—but with today’s endovascular technology, should that dogma be challenged?In this MurmurMD session, vascular surgeon Dr. Nick Mouawad joins Dr. Sameh Sayfo for a deep dive into how modern tools (IVUS, intravascular lithotripsy, advanced classification systems, and hybrid-OR workflow) are reshaping the way we evaluate and treat common femoral artery disease.Using real-world experience and early data from investigative studies, the conversation covers:• When to intervene on common femoral disease• CTA vs duplex for pre-op planning• How hybrid ORs change strategy and bailout options• Key differences between acute limb ischemia vs chronic CLTI femoral exposure• Why wound complications and groin integrity matter• Which patients surgeons worry about most• The rise of IVUS for sizing and anatomical confirmation• How IVL (M5+, L6) is changing luminal gain and safety• Why common femoral arteries are far larger than traditionally assumed• Challenges: lack of large-bore DCBs, bifurcation disease, proximal spillover• What future device platforms are still missing• Early trial design lessons comparing IVL + DCB vs endarterectomyA must-watch for anyone treating inflow disease, CLTI, or evaluating whether femoral interventions can be safely expanded beyond surgery alone.Chapters:00:00 – Introduction and setting the stage 01:00 – Why common femoral disease is a “sacred surgical zone” 02:00 – Indications for treating common femoral artery lesions 03:00 – Imaging workup: ultrasound vs CT 04:00 – When hybrid ORs become essential 05:00 – Acute limb vs chronic femoral disease: what changes surgically 06:30 – Groin complications and what surgeons fear most 08:00 – Patient types that raise surgical risk 09:00 – The durability of endarterectomy vs risks in fragile patients 10:00 – Why endovascular solutions matter for modern PAD demographics 11:00 – The biggest danger of early endovascular CFA therapy: dissection 12:00 – What technologies surgeons want when considering endovascular CFA work 13:00 – Calcification patterns and why IVL changed the game 14:00 – IVUS for femoral sizing: why CFA vessels are bigger than we thought 15:00 – Limitations: maximum DCB sizes and when they fall short 16:00 – L6 vs M5+: how the devices differ and when to use each 17:00 – European data on CFA stenting and bifurcation techniques 18:00 – Trial design: how to avoid bias when comparing endo vs open 19:00 – Classification systems (Ozema, Rapolino) and choosing appropriate patients 20:00 – Early lessons from IVL + DCB vs surgery investigation 21:00 – Future technologies needed for CFA therapy 22:00 – Closing thoughts: hybrid strategies and patient selection🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#PeripheralArteryDisease #CommonFemoralArtery #IVL #IVUS #VascularSurgery #Endovascular #CLTI #PAD #HybridOR #MurmurMD #L6 #M5Plus #DCB #CalciumModification

  22. 25

    CTO PCI Simplified: Dr. Robert Riley’s Step-by-Step IVUS Sighted ADR Technique with Dr. Chris Brown

    ADR (Antegrade Dissection and Re-Entry) has historically been viewed as unpredictable — but with a structured, IVUS-sighted approach, it becomes one of the most consistent and controllable CTO PCI techniques.In this detailed case walkthrough, Dr. Robert Riley demonstrates how he performs an IVUS-Sighted ADR workflow during a complex RCA CTO. He explains how to select landing zones, create a controlled knuckle, prevent hematoma formation, orient the Stingray system correctly, and re-enter the true lumen with precision.Topics you’ll learn:When ADR is the correct strategy for a long CTOIdentifying a clean distal landing zone using IVUSHow to form a stable knuckle with the Pilot 200The purpose of de-escalating to Mongo for safer advancementHematoma prevention with guide extension supportHow retrograde angiography guides Stingray orientationVacuum decompression (“straw technique”) for clearing the subintimal spaceStick-and-drive vs stick-and-swap re-entry patternsUsing IVUS to confirm true lumen passage and guide stent sizeAvoiding the most common ADR failure modesThis is a foundational training for operators refining modern ADR technique with IVUS guidance.Chapters:00:00 – Why ADR still matters in modern CTO PCI 01:00 – When ADR is favored over wire escalation 02:00 – Identifying the distal landing zone with IVUS 03:30 – RCA CTO setup and planning 05:30 – Bifemoral access and guide selection 06:30 – Creating a knuckle with the Pilot 200 08:30 – De-escalating the knuckle and reducing subintimal trauma 10:30 – Guide extension support and pressure control 11:30 – Stingray preparation and system orientation 12:30 – Selecting the correct projection angle 14:00 – Retrograde angiography for confirmation 15:00 – Vacuum decompression (“straw technique”) 17:00 – Stick-and-swap method to regain the true lumen 19:00 – IVUS confirmation and how to size stents correctly 21:00 – Final angiographic review and procedural takeaways🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#CTO #ADR #IVUS #InterventionalCardiology #ComplexPCI #Stingray #Pilot200 #MongoWire #CathLab #MurmurMD

  23. 24

    TAVR Valve Choice, Coronary Access, and the Lifetime Valve Mindset: Case discussion with Dr. Matt Summers and Dr. Aidan Raney

    TAVR isn’t just a procedure anymore — it’s a lifetime management decision.In this in-depth case discussion, Dr. Matt Summers and Dr. Aiden Raney dive into how hemodynamics, modeling tools, and device design are reshaping how operators approach valve selection, coronary access, and reintervention planning.Key insights include:Real-world cases showing how valve selection has evolved since 2018Using DASI modeling to predict sinus sequestration and coronary riskHow Shortcut has simplified bilateral leaflet modification and reduced procedure timesLessons learned from redo-TAVR failures, pannus formation, and HALTWhy younger and bicuspid patients still favor surgical approachesHow commissural alignment and annular eccentricity guide modern valve choiceWhen and how to tackle coronary intervention through TAVR framesThe importance of hemodynamics over “comfort” in valve selectionThis is a must-watch for interventional cardiologists aiming to merge clinical intuition with device innovation and predictive modeling for long-term outcomes.Chapters:00:00 – Revisiting early valve-in-valve planning 01:00 – How modeling (DOSI) predicts coronary occlusion risk 02:20 – Shortcut vs. Basilica: evolution in leaflet modification 04:00 – Purpose-built devices reducing case time and risk 05:00 – When Shortcut changes your threshold for leaflet splitting 07:00 – Lessons from redo-TAVR and pannus formation 10:00 – Why bicuspid and young patients often need surgery 13:00 – The coronary access problem that taught a hard lesson 16:00 – Commissural alignment as the key to reintervention success 18:00 – Doing left main PCI through a fresh TAVR 20:00 – Horizontal aortas and catheter flexibility 22:00 – Hemodynamics as the foundation of valve choice 24:00 – Building a lifetime valve strategy for every patient🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#TAVR #StructuralHeart #ValveInValve #LeafletModification #PredictiveModeling #CommissuralAlignment #InterventionalCardiology #DOSI #CoronaryAccess #MurmurMD

  24. 23

    How AI and Predictive Modeling Are Changing TAVR Valve Selection with Dr. Matthew Summers and Dr. Aidan Raney

    TAVR has come a long way—from a high-risk bailout procedure to a precision-driven, patient-specific therapy.In this MurmurMD case discussion, Dr. Matt Summers (Sentara Heart Valve Center) joins Dr. Aiden Raney to explore how new data, AI modeling, and simulation tools like DASI are transforming how interventionalists choose between self-expanding and balloon-expandable valves. A real look into contemporary approaches to valve therapy decisions.Key insights covered:The evolution from procedural survival to lifetime valve strategyHow hemodynamics and durability data are reshaping valve selectionUsing predictive modeling (DASI) to prevent annular rupture and coronary occlusionReal-world lessons from redo TAVR and valve-in-valve proceduresWhy commissural alignment and cusp overlap have changed the gameWhat next-generation AI tools mean for precision TAVR planningHow large-volume centers are integrating data, imaging, and simulation into every caseThis conversation bridges clinical intuition with digital precision, offering a glimpse into how the next era of TAVR will be designed—patient by patient, model by model.Chapters:00:00 – Introduction and evolution of TAVR therapy 01:00 – From high-risk to precision: how TAVR decision-making has evolved 02:30 – Valve selection: BEV vs SEV and the 16 decision factors 04:00 – Durability, hemodynamics, and small annulus data 06:00 – What the SMART and Notion trials revealed about performance 08:00 – Coronary access, explant, and the penalty of being wrong 10:00 – AI modeling and pre-procedural simulation (DASI) 12:00 – Predicting rupture, occlusion, and leaflet modification needs 14:00 – Impact of modeling on procedural planning and outcomes 16:00 – Planning for the second valve: true lifetime management 18:00 – Future vision: Precision TAVR through AI-guided design🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#TAVR #StructuralHeart #InterventionalCardiology #MurmurMD #PredictiveModeling #DASI #ValveSelection #HeartValve #CathLabInnovation

  25. 22

    From Idea to Market: How to build a medical device company for physicians featuring Dr. David Daniels and Dr. Joe Walsh

    Physicians Building Devices: Powering the Next Wave of Cardiovascular InnovationNot in boardrooms—but in cath labs, by operators sharing cases, data, and ideas in real time.In this episode, Dr. David Daniels and Dr. Joe Walsh dive into how platforms like MurmurMD are connecting physicians, engineers, and startups to accelerate device innovation from the front lines of interventional cardiology.Key themes and insights:Why innovation starts with operators identifying real problems in the labHow peer-to-peer case sharing is shortening the feedback loop between users and buildersTurning complication management into product-development insightThe role of data transparency and outcomes sharing in improving next-gen designsCollaborating across teams—engineers, industry, and interventionalists—without silosWhy speed, iteration, and feedback now define modern cardiovascular innovationA preview on physician-built ecosystem for device advancementThis is essential viewing for clinicians, startups, and innovators who believe the future of medtech is built inside the cath lab, not outside it.00:00 – Intro: Building devices from inside the cath lab 01:00 – Why innovation begins with frustration in the lab 02:15 – From case sharing to concept generation 03:30 – Turning complications into design opportunities 05:00 – The value of rapid feedback between operators and engineers 07:00 – Data as fuel: how shared outcomes guide better devices 09:00 – Creating a two-way bridge between clinicians and companies 11:00 – Vision: crowdsourced device evolution 12:30 – Real-time learning → real-time innovation 14:00 – How open conversation accelerates safe experimentation 15:30 – Next steps: empowering physician-engineer collaboration🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#MedTech #DeviceInnovation #MurmurMD #InterventionalCardiology #StructuralHeart #CathLab #ClinicalInnovation #PhysicianEntrepreneur #MedicalDevices #MurmurMDLive

  26. 21

    ALT-FLOW II Trial: Shunting Innovation for HFpEF and Beyond with Dr. Firas Zahr and Dr. Andrei Pop

    Can creating a shunt between the left atrium and the coronary sinus improve symptoms for patients with heart failure with preserved ejection fraction (HFpEF)?In this in-depth discussion, Dr. Andrei Pop and Dr. Firas Zahr, PI of the ALT-FLOW II Trial, explore the science, physiology, and patient selection behind one of the most intriguing new frontiers in interventional heart failure.Key takeaways:What makes ALT-FLOW different from previous intra-atrial shunt devicesHow shunt location, size, and flow patterns affect outcomesWhich heart failure patients respond best — HFpEF, HFrEF, or mixed phenotypesWhy resting wedge pressures don’t predict exercise hemodynamicsThe importance of exercise right heart catheterization and PCWL measurementInsights on stroke risk and why preserving the atrial septum may matter for lifetime proceduresHow ALT-FLOW maintains procedural simplicity and safety through the coronary sinus approachExpanding the field of interventional heart failure and device-based diastolic therapiesThis conversation is essential for structural heart and heart failure specialists exploring new options for symptomatic HFpEF patients in the modern era of shunt-based therapy.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Intro: The rise of interventional heart failure 00:45 – What makes the ALT-FLOW device unique 01:20 – Lessons learned from prior shunt trials 02:30 – Which patients may benefit most 04:00 – Persistent symptoms after valve repair and TAVR 05:00 – Stroke risk and shunt design safety 06:30 – Importance of preserving the interatrial septum 07:00 – Exercise right heart catheterization and PCWL 08:30 – What exercise reveals about true physiology 10:30 – When wedge pressures tell the real story 12:00 – Expanding tools for diastolic dysfunction 13:30 – Sham control and endpoint selection in ALT-FLOW II 15:30 – Heart failure specialists re-engaging with HFpEF 17:00 – Pacemaker leads and coronary sinus access 18:00 – Future of interventional heart failure 19:30 – Industry, innovation, and economics of device therapy 21:00 – Safety data and operator experience so far 23:00 – Future: Finding the right HFpEF subsets 24:30 – Closing reflections and next steps in research#ALTFlow #HFpEF #HeartFailure #StructuralHeart #InterventionalCardiology #CoronarySinusShunt #HeartFailureDevice #CathLab #MurmurMD

  27. 20

    Impella 5.5 for AVR: Surgical Strategy, Weaning, & Patient Mobilization with Dr. Roland Hernandez and Dr. Chris Brown

    How do surgeons decide when to place an Impella 5.5 before valve surgery?In this discussion, Dr. Roland Hernandez walks through his operative approach with Dr. Chris Brown, covering:Patient selection: when balloon pump isn’t enough supportStep-by-step technique for direct aortic Impella 5.5 insertionHow to tunnel and remove the graft safelyTechnical pearls for cross-clamp position and avoiding floodingStrategies for weaning from bypass to ImpellaCommon hazards: wire and catheter challenges for surgeonsWhy mobilization is critical and when Impella CP isn’t enoughThis case-based conversation offers a rare surgeon-to-interventionalist perspective on advanced mechanical circulatory support.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Intro & guest background 00:45 – Patient case: severe LV dysfunction, AI + MR 02:10 – Why Impella 5.5 over balloon pump 03:20 – Preemptive strategy & surgical planning 03:40 – Direct aortic Impella 5.5 implantation technique 04:45 – Graft tunneling, closure, and removal details 06:20 – Operative sequence & bypass setup 08:10 – Positioning, cross-clamp, and cannulation pearls 09:00 – Valve replacement + Impella insertion steps 10:20 – Weaning from bypass to Impella support 12:00 – Technical challenges: wires & catheters 13:20 – Axillary vs supraclavicular approach considerations 14:30 – Hazards of clamp position & LV flooding 15:45 – Manipulating the device intra-op 16:10 – Deciding level of support: index, EF, gestalt 17:20 – Post-op outcomes, shock scenarios, and red flags 18:40 – Mobilization benefits: why 5.5 beats CP 20:00 – Closing thoughts & key lessons#Impella #MechanicalSupport #CardiacSurgery #AVR #InterventionalCardiology #TAVR #HeartFailure #MCS #Impella55 #MurmurMD

  28. 19

    TAVR-in-TAVR Gradients Explained: Flow, Expansion & Patient Outcomes with Dr. Amr Abbas and Dr. Andrei Pop

    What really drives gradients after TAVR-in-TAVR—and do they actually matter?In this conversation, Dr. Amr Abbas and Dr. Andrei Pop break down the nuances behind gradient measurements, patient-prosthesis mismatch (PPM), and valve expansion strategy in redo TAVR.Key takeaways include:Why echo gradients differ from invasive gradients even under identical hemodynamicsUnderstanding discordance between flow and pressure in post-TAVR assessmentWhy PPM is less concerning in normal-flow patients than previously believedHow flow state—not gradient—drives outcomes after TAVR or SAVRThe role of predicted vs measured PPM and valve-specific flow patternsInsights on undersizing vs overexpansion and how to optimize redo TAVR resultsWhy well-expanded valves may outperform “bigger” but underexpanded onesHow lifetime management means moving past numbers to patient-centered outcomesThis is a must-watch for interventional cardiologists and structural heart teams focused on redo TAVR planning, flow hemodynamics, and lifetime valve strategies.00:00 – Introduction: TAVR-in-TAVR and gradient anxiety 01:10 – Invasive vs echo gradients: why they don’t match 03:00 – Discordance and measurement error in post-TAVR gradients 04:25 – Understanding pre-discharge echo gradient increases 05:15 – When gradients are “nuisance” findings vs real issues 06:00 – PPM redefined: what echo really measures 07:30 – Flow-derived valve area and its pitfalls 09:00 – Flow vs gradient: the real driver of outcomes 10:00 – Lessons from the PARTNER and TVT data 12:30 – Predicted vs measured PPM in clinical context 14:00 – The role of ejection fraction and low-flow states 16:00 – Flow patterns: laminar vs turbulent impact on velocity 18:00 – Valve sizing: smaller expanded vs larger underexpanded 20:00 – Expansion optimization and stent analogy 22:00 – Valve labeling, true ID, and expansion limits 24:30 – Historical shift: from “biggest valve possible” to “best expansion possible” 26:30 – Oversizing risks, skirts, and modern generation valves 28:00 – The balance between PVL, pacemaker risk, and expansion 30:00 – Lifetime management: beyond numbers to patient outcomes 31:00 – Closing thoughts & takeaways#TAVR #ValveInValve #TAVinTAV #InterventionalCardiology #StructuralHeart #Echocardiography #AorticValve #PPM #Hemodynamics #MurmurMD

  29. 18

    DEFINE GPS Trial: Physiologic PCI Guidance, Co-Registration, & Surprising Case Lessons

    How often do patients leave the cath lab with residual ischemia—and can physiologic guidance change outcomes?In this discussion, Dr. Chris Brown and Dr. Christian McNeely review insights from the DEFINE GPS Trial, where PCI guided by pressure wire co-registration was compared with angiography alone.Key highlights:- Why 20% of patients left the lab with residual ischemia in DEFINE PCI- How FFR/iFR pullback and co-registration create a physiologic roadmap for stenting- Trial design, enrollment (2,100 patients), and endpoints: MACE at 1–2 years- Surprising cases where physiology overturned angiographic impressions- Calcium, long lesions, and the limits of angiography alone- When to trust physiology vs imaging—IVUS/IVL integration- The future role of co-registration software in routine PCIThis is a must-watch for interventional cardiologists looking to integrate objective physiologic data into daily practice.Like and subscribe to see more!Follow the MurmurMD Youtube for more tips: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvADownload the MurmurMD app here: https://apps.apple.com/app/apple-store/id1586692687?pt=123231498&ct=curtis&mt=800:00 – Intro & guest background 00:39 – Define GPS trial design & objectives 01:17 – Residual ischemia: lessons from Define PCI 02:23 – Co-registration system explained 03:09 – Inclusion criteria & patient population 03:53 – Endpoints: MACE at 1–2 years 04:07 – Enrollment: 2,100 patients, top enrolling sites 04:25 – Why angiography alone misses physiology 05:12 – Standard PCI workflow vs physiologic pullback 06:30 – Case 1: circumflex calcification & LAD ischemia 07:41 – Co-registration mechanics step-by-step 09:12 – Post-PCI IFR goals & physiologic success 11:31 – IVUS co-registration and stent sizing pearls 12:46 – Calcium, long lesions & turbulence effects 13:43 – Taking subjectivity out of angiography 15:22 – Physiology + imaging: additive or redundant? 16:43 – Aggressive stent sizing & perforation risk 17:28 – Case 2: non-STEMI with PDA & focal circ lesion 18:51 – Pullback showing ischemia dots at stenosis 20:10 – Why physiology prevented unnecessary stenting 21:49 – Which lesions should we defer vs treat? 22:17 – Looking ahead: Define GPS trial results (2026–27)#DefineGPS #PCI #InterventionalCardiology #FFR #iFR #CoRegistration #CathLab #StructuralHeart #StentOptimization #MurmurMD

  30. 17

    LAAC Imaging in 2025: 3D ICE vs TEE—Techniques, Safety & Workflow | SWAC Panel Sept. '25

    How is left atrial appendage closure (LAAC) evolving in 2025—and what’s the role of 3D ICE vs TEE?In this SWAC session, Dr. Matthew Price and panelists share their real-world experiences and expert pearls:Why 3D ICE is becoming the standard for Watchman and Amulet proceduresKey tips to avoid air embolism and manage sedation risksHow to safely perform ICE-guided transseptal puncture and LAA imagingWhen TEE or mini-TEE probes remain the better optionCost, staffing, and program scaling strategies for high-volume centersPractical steps for single-operator workflows and nursing team integrationWhether you’re a structural heart imager, interventional cardiologist, or part of a valve clinic team, this discussion highlights the future of LAAC imaging and what it takes to safely scale programs as patient volumes grow.00:00 – Welcome & panel introduction 00:18 – Why imaging is critical for LAAC in 2025 00:37 – Matthew Price: 3D ICE is the future for Watchman and Amulet 01:03 – Boston Scientific advisory on air emboli 01:50 – Why 3D ICE outperforms 2D ICE for moderate sedation 02:11 – NCDR registry data on ICE vs TEE outcomes 02:40 – Learning curve and case volume to master ICE 03:42 – Practical workflow: efficient 3D ICE case steps 05:42 – Pre-procedure CT planning and AI sizing tools (FEOPS, DASHI) 07:11 – Tips for safe transseptal puncture with ICE guidance 09:04 – Balloon dilation vs delivery sheath crossing strategies 13:14 – Using fluoro as a backup for ICE alignment 18:08 – Aligning the ICE view to the LAA axis for accurate deployment 28:12 – Preventing air embolism during sedation-only cases 31:18 – Hydration, LA pressure checks, and sheath management 35:17 – When to choose TEE: obesity, severe OSA, or complex mitral work 40:17 – Mini-TEE probes: workflow advantages under MAC 47:01 – Pre-procedural imaging vs on-table imaging debate 52:09 – High-volume GA workflows and 4-minute deployment case 53:08 – Panel takeaways: scaling LAAC imaging programs#LAAC #Watchman #3DICE #TEE #InterventionalCardiology#StructuralHeart #CathLab #LAAO #ModerateSedation #MurmurMD

  31. 16

    Conscious Sedation LAAO with ICE: Building a Solo-Operator WATCHMAN Program with Dr. Gollapudi

    Can you safely perform left atrial appendage occlusion (LAAO) without TEE, anesthesia, or an echo doc?In this episode, Dr. Raghava Gollapudi (San Diego Cardiac Center) and colleagues break down how they built a conscious sedation, ICE-only LAAO program in private practice. They cover:- Why traditional TEE + anesthesia models slow scheduling and add variability- Evidence from Europe showing ICE-only Watchman is safe- How to transition from TEE support to ICE-only workflow- Practical pearls for ICE catheter handling, transeptal crossing, and imaging- Patient selection: absolute and relative contraindications- The role of nursing staff and team buy-in- Why 3D/4D ICE makes device visualization easierThis is a must-watch for operators and program builders looking to simplify workflows and improve access to LAAO.⏱️ Chapters00:00 – Intro & program overview01:00 – Why conscious sedation for LAAO?02:00 – Limitations of TEE + anesthesia model02:45 – Evidence for ICE-only Watchman safety03:30 – Becoming a solo-operator with ICE04:45 – Transition: 20 cases with TEE + ICE06:00 – Patient selection: contraindications & risks08:00 – Screening tools & nursing involvement09:00 – Step-by-step ICE technique & home views10:30 – Transeptal crossing: tips, 3-minute rule12:00 – Biggest barrier: ICE-only septal crossing14:00 – Imaging the appendage: mid & low angle views15:45 – Benefits of 3D/4D ICE vs 2D ICE16:30 – Final pearls for solo-operator LAAO🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-stor...#LAAO #Watchman #ConsciousSedation #ICEImaging #InterventionalCardiology #StructuralHeart #CathLab #AtrialFibrillation #SoloOperator #murmurmd

  32. 15

    How to Build a World-Class Research Program: Lessons from Dr. Thomas Waggoner

    A look into how Dr. Waggoner took a new TAVR program and transformed it into a top-tier research hub from scratch! Dr. Tom Wagner, Director of Structural Heart at Tucson Medical Center, shares his journey in building a research-first culture from scratch. In this conversation, he discusses:Why research is a differentiator in regional cardiologyHow he grew from zero research to 70+ active clinical trialsThe inflection point when a program takes off (around year 5)The importance of volume, outcomes, and clean data for sponsor trustPractical insights on staffing: from one CRC to a full research hierarchyWhy perseverance, weekends, and attention to detail are the real “secret sauce”How research fuels both patient access to novel devices and institutional reputationWhether you’re a structural cardiologist, program director, or part of a valve team, this discussion offers a roadmap to building research infrastructure that benefits both patients and institutions.Chapters:00:00 – Intro & guest background 01:10 – Starting with zero research & 50 TAVRs/year 02:00 – Why research matters for program growth 03:30 – Research as a differentiator in regional markets 04:10 – Perseverance: the real “secret sauce” 05:30 – Balancing call, STEMI, and research demands 06:20 – The 5-year inflection point of growth 07:00 – From 2 trials to 70: scaling the research portfolio 07:45 – Importance of high volume and outcomes 08:15 – Why clean data builds sponsor trust 09:30 – Don’t overreach: starting with the right trial 10:20 – Building staff: from one CRC to a full hierarchy 12:00 – Lessons learned from early trial missteps 13:00 – Closing insights on building lasting programs#StructuralHeart #CardiologyResearch #TAVR #HighRiskPCI #InterventionalCardiology #ClinicalTrials #CathLab #ValveTeam #ResearchProgram #MurmurMD

  33. 14

    The Ross Procedure: Modern Techniques, Durability, & Lifetime Valve Management with Dr. Malaisrie and Dr. Pop

    Once considered niche, the Ross procedure is making a strong comeback. With improved techniques and long-term outcomes, it’s becoming a first-line option for younger patients with aortic valve disease.In this episode, Dr. Chris Malaisrie (Northwestern Memorial, Chicago) joins Dr. Andrei Pop to discuss:Why the Ross procedure is resurging in high-volume centersTechniques to stabilize the autograft and prevent dilation (deep LVOT implant, Dacron grafts, wrapping with native root)Post-op strategies including strict blood pressure control for favorable remodelingDurability data: 85–90% freedom from reintervention at 10 yearsManaging failures: surgical re-repair, TAVR options, and future dedicated devicesPatient selection: under 50, women, and those with small aortic rootsThe role of root enlargement and replacement in lifetime managementMinimally invasive approaches: mini-thoracotomy vs sternotomyTAVR-first vs surgery-first strategies in younger patientsWhy the valve clinic model and shared decision-making matter in 2025This is a must-watch for surgeons, interventional cardiologists, and valve clinic teams navigating lifetime aortic valve management.Chapters:00:00 – Intro & guest background 01:00 – Why the Ross procedure is resurging 02:15 – Stabilizing the autograft: surgical techniques 04:00 – Blood pressure control & early remodeling 05:20 – Jacketed Ross and long-term durability 06:30 – Failure rates and freedom from reintervention 07:15 – Options for failing autografts & future TAVR devices 10:30 – Homografts vs autografts: differences in calcification 12:00 – Ross volumes, outcomes, and national trends 13:30 – Patient selection: under 50, women, and small roots 14:15 – Root enlargement and replacement strategies 20:00 – CT planning and AI modeling for AVR 21:15 – Minimally invasive AVR: mini-thoracotomy vs sternotomy 22:15 – TAVR first vs Ross first in younger patients 23:30 – Challenges with TAVR explant vs SAVR explant 26:00 – Techniques for safe TAVR explant 27:00 – TAV-in-TAV as a lifetime strategy 28:30 – Coronary protection & unicorn procedure 31:30 – Valve clinics & shared decision-making 33:15 – The debate over single-operator TAVR 35:00 – Closing thoughts & takeaways#RossProcedure #AorticValve #CardiacSurgery #ValveSurgery #StructuralHeart #TAVR #LifetimeManagement #ValveClinic #InterventionalCardiology #MurmurMD

  34. 13

    TAVR Explant: Why Mortality Is Dropping & How Surgeons Are Changing the Game featuring Dr. Kaneko and Dr. Pop

    TAVR explants were once considered high-risk, last-resort surgeries—with mortality rates as high as 18–20%. But recent data and surgical advances are changing the conversation.In this episode, Dr. Tsuyoshi Kaneko, Director of Cardiothoracic Surgery at Washington University in St. Louis, joins Dr. Andrei Pop to discuss:Why TAVR explant rates are rising and who needs themHow mortality has dropped to 5–6% in recent seriesThe impact of standardized techniques and better patient selectionStrategies for small root management and planning for future valve-in-valveWhen to choose TAVR explant vs. TAVR-in-TAVRThe role of early referrals and multidisciplinary valve teamsWhether you’re a cardiologist, surgeon, or part of a structural heart team, this conversation is packed with practical pearls for lifetime management of aortic valve disease.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Intro & why TAVR explant matters 01:20 – Early mortality data & fears in the field 03:50 – Why outcomes are improving 05:35 – Patient selection & referral timing 08:00 – Updated STS risk calculator for TAVR explant 10:25 – Centers of expertise & complex root work 13:15 – Techniques for small root management 15:45 – Explant after valve-in-valve TAVR 18:00 – Balloon vs. self-expanding valve challenges 20:20 – Snorkel stents and surgical headaches 22:00 – Implant strategy anticipating lifetime management 24:15 – TAVR first? The bicuspid debate 27:00 – Lifetime management beyond the first procedure 28:35 – Final thoughts on team approach#TAVR #CardiothoracicSurgery #AorticValve #ValveInValve #HeartTeam #StructuralHeart #TAVRExplant #AorticRoot #InterventionalCardiology #MurmurMD

  35. 12

    Changing the Paradigm of Aortic Stenosis Treatment featuring Dr. Philippe Genereaux

    PCI in Complex CAD: Imaging, Physiology & Patient-Centered Decision Making with Dr. Philippe Genereux, Dr. Joe Walsh, and Dr. Aidan RaneyWhat role should imaging and physiology play when tackling complex CAD?In this condensed discussion, Dr. Philippe Genereux (Morristown Medical Center) shares his approach to optimizing PCI and balancing data, experience, and patient outcomes. Key takeaways include:When to rely on FFR vs IVUS/OCT in PCI decision-makingCase selection pearls in left main and bifurcation diseaseInsights on DK crush, provisional stenting, and simplicity vs complexityWhy lifetime management matters more than short-term resultsHow patient values and comorbidities shape the best strategyThoughts on consensus vs operator judgment in modern PCIIf you’re a cardiologist working with complex coronary disease, this session delivers concise, practical wisdom from one of the field’s most respected interventionalists.Chapters:00:00 – Welcome & topic overview 00:50 – Imaging vs physiology: where to start 03:00 – FFR insights in complex PCI 05:15 – Role of IVUS/OCT in left main & bifurcation disease 08:00 – Stenting strategies: DK crush vs provisional 10:30 – Balancing simplicity, complexity, and long-term planning 13:15 – Patient-centered decision making & comorbidities 15:00 – Consensus guidelines vs operator judgment 16:30 – Key takeaways & closing remarks #PCI #InterventionalCardiology #IVUS #OCT #FFR #ComplexPCI #Bifurcation #LeftMain #CoronaryArteryDisease #MurmurMD #Cardiology #Medical #Education

  36. 11

    Building a High-Risk PCI & Shock Program Without Surgical Backup with Dr. Mahesh Anantha & Dr. Chris Brown

    Can you build a complex PCI and cardiogenic shock program in a community hospital without surgical backup?Dr. Mahesh Ananta shares his journey from type A/B PCI to performing Impella-, ECMO-, and CTO-supported interventions in a small hospital setting. Learn how he:Scaled a high-risk PCI program with minimal resourcesImplemented Impella and ECMO safely without in-house CT surgeryJoined a cardiogenic shock network to improve outcomesNavigated hospital culture and financial conversationsTrained staff and changed cath lab culture for long-term successIf you’re building a peripheral or coronary MCS program—or facing resource limitations—this discussion is packed with real-world pearls for program growth, safety, and sustainability.🔔 Subscribe for more insights from interventional experts and real-world program builders.📱 Download the app: https://apps.apple.com/app/apple-store/id1586692687📺 Follow us on YouTube: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvAChapters:00:00 – Intro: Building a program without surgical backup 01:00 – Starting with type A/B PCI and early limitations 02:00 – Adding atherectomy, Impella, and ECMO safely 03:30 – Joining the Arkansas Cardiogenic Shock Initiative 05:00 – Convincing admin: outcomes + financial conversations 07:30 – First mechanical support cases and stepwise strategy 09:30 – Maintaining skills while minimizing early complications 12:00 – Training cath lab staff and changing local culture 14:40 – Leveraging industry support for devices and education 18:00 – Building trust with ICU and small-community dynamics 20:45 – Lessons for physicians building new programs #HighRiskPCI #Impella #ECMO #CardiogenicShock #InterventionalCardiology #CathLabCulture #CTOIntervention #HospitalLeadership #MCS #MurmurMD

  37. 10

    Mastering Short-in-Tall TAVR: Valve-in-Valve Sizing, Anchoring, and Lifetime Management with Dr. Gilbert Tang

    Short-in-tall TAVR (Sapien-in-Evolut) presents unique challenges in valve sizing, anchoring, and long-term durability. In this in-depth discussion, Dr. Andrei Pop and Dr. Gilbert Tang (Mount Sinai, Structural Heart Program Director) break down their real-world approach to:Accurate CT-based sizing for valve-in-valve proceduresOversizing and volume strategies for AR vs ASAnchoring techniques to prevent delayed migrationNode 4, 5, and 6 implantation strategies and leaflet overhang concernsPre- and post-dilation pearls for safety and durabilityLifetime management, surgical considerations, and simulation insightsIf you perform valve-in-valve TAVR, this episode delivers practical pearls for safer and more durable outcomes.🔔 Subscribe for more advanced TAVR and structural heart discussions.Timestamps:00:00 – Welcome & Intro to Short-in-Tall TAVR 01:15 – Why Sapien-in-Evolut is Challenging 02:13 – CT Sizing & Oversizing for AR vs AS 06:30 – Anchoring, Gaps, and Delayed Migration Risk 09:00 – Node 4, 5, 6 Implant Strategies & Leaflet Overhang 14:45 – Predilation & Managing Hemodynamics 18:04 – Post-Dilation & Frame-to-Frame Optimization 23:15 – Bench vs In Vivo Behavior & Watermelon Seeding 30:21 – Valve Explant vs Second Valve: Lifetime Management 34:07 – Surgical Tips: Root Enlargement & Coronary Access 39:02 – DASI Simulations & Coronary Protection Pearls 40:47 – Closing Thoughts & Key Takeaways #TAVR #ValveInValve #ShortInTall #StructuralHeart #InterventionalCardiology #Sapien #Evolut #ValveDurability #CoronaryProtection #CardiologyEducation #HeartTeam #TAVRStrategy #MurmurMD

  38. 9

    Nurse-Led Sedation for TAVR: How Dr. Dahle Boosted Throughput and Cut Costs

    Can nurse-led sedation transform your TAVR program?Dr. Thom Dahle, Director of Valvular Heart Disease at CentraCare Heart & Vascular Center, shares how his team successfully transitioned from anesthesia-led to nurse-led sedation — and the results are eye-opening. From drastically improving throughput and consistency to dramatically reducing costs, Tom explains how this minimalist approach redefined workflows, improved patient recovery, and strengthened team dynamics.Key insights:Why they moved TAVR out of the OR and into the cath labHow they trained nurses to lead safe, effective sedationHow to handle anesthesia buy-in and manage rare complicationsWhat protocols and communication strategies made it all possibleCost savings and workflow improvements you can replicateTom also shares his entrepreneurial journey as the owner of the largest axe-throwing bar in the Southeast — and how those business lessons apply in medicine.📌 Whether you're planning to optimize your TAVR program or just want ideas to improve efficiency, this is a must-watch.#TAVR #StructuralHeart #CathLab #NurseLedSedation #InterventionalCardiology #MurmurMD

  39. 8

    All Leaks Matter? Re-Thinking Peri-Device Leak Significance in LAA Closure with Dr. Michael Rinaldi

    Do all leaks matter in Left Atrial Appendage Closure?Dr. Michael Rinaldi, Director of Structural Heart at Sanger Heart & Vascular Institute, offers a deep dive into the evolving science of peri-device leaks during LAAC. In this insightful discussion, he explores which leaks carry stroke risk, how device technology is changing the game, and what imaging and sizing strategies are most effective.Topics covered include:Stroke risk: how much do small leaks actually increase it?Why leaks over 3mm are the new threshold of concernKey differences between Watchman and Amulet devicesWatchman Flex and Flex Pro: reduced leak rates and improved safetyThe role of ICE vs TEE in modern workflowsTips on device sizing, oversizing, and how to avoid DRTWhen to intervene (and when to observe)Use of TrueSteer and the shift toward minimalist proceduresIf you’re a structural heart or interventional cardiologist, this is a must-watch to help guide your clinical decision-making and device selection.Follow the MurmurMD YouTube channel for more expert content: / @murmurmd Download the MurmurMD app here: https://apps.apple.com/app/apple-stor...#Cardiology #LAAC #Watchman #TEE #ICE #StructuralHeart #CathLab #strokeprevention 00:00 Introduction by Dr. Elliot Groves 00:18 Dr. Michael Rinaldi Joins the Discussion 00:50 Do All Leaks Really Matter? 01:36 Stroke Risk with Small Peri-Device Leaks 02:21 Understanding Leak Size and Stroke Magnitude 03:05 Types of Device Leaks Explained 04:03 Device Differences: Watchman vs Amulet 05:23 Confounders in Stroke Risk Assessment 06:09 Should We Intervene on Small Leaks? 06:43 Why 3mm Is the New Leak Cutoff 07:07 Clinical Significance of Small Crescentic Leaks 07:40 How Watchman Flex Changed Leak Rates 08:10 Data from PROTECT, OPTION, and CHAMPION Trials 08:39 The Future of Imaging: ICE vs TEE 09:32 Minimalist Workflow and Resource Constraints 10:19 Better Imaging, Better Devices: What’s Next? 10:36 Summary: Which Leaks Matter Most? 11:13 Deployment Tips to Minimize Leaks 12:10 When to Intervene and When to Observe 13:04 Caution Against Overusing Coils and Plugs 14:04 Debating Device Oversizing Strategies 15:05 Oversizing vs Stability: Finding the Sweet Spot 16:35 Compression, DRT, and the Ice Cream Cone Effect 17:11 Where TruSteer Makes a Difference 18:02 Why Watchman Flex Works for Most Appendages 20:08 Final Thoughts on Device Selection 21:30 Closing Remarks and Community Discussion

  40. 7

    How to Double Your WATCHMAN Volume: 5 Proven Strategies from Two High-Growth Programs

    Ready to take your LAAC program to the next level?Dr. Joe Walsh breaks down five actionable strategies that have helped dramatically grow WATCHMAN implant volumes — not in theory, but in real-world cath labs. Joined by Dr. Samuel Horr, the two discuss how their programs overcame common hurdles, scaled smartly, and drove sustained growth through simple yet strategic changes.Whether you’re building a program from scratch or optimizing an existing one, this video delivers practical, replicable insights from physicians in the field.➡️ Learn what’s actually working➡️ Hear how others implemented it successfully➡️ Get inspired to level up your structural heart program🔔 Subscribe for more cardiology insights👥 Join the conversation on MurmurMD📲 Download the MurmurMD App:https://apps.apple.com/app/apple-store/id1586692687?pt=123231498&ct=curtis&mt=8▶️ Follow MurmurMD on YouTube:https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA#WATCHMAN #LAAC #cardiology #structuralheart #cathlab #interventionalcardiology #MurmurMD #medicalinnovation

  41. 6

    The Sideclose Technique- a full guide from creator Dr. Jason Wollmuth

    Stopping Bleeding with Impella: Dr. Jason Wollmuth’s Sideclose TechniqueDr. Jason Wollmuth introduces a groundbreaking solution to a persistent challenge in Impella support — managing bleeding. In this episode, he walks through the Sideclose technique, a simple yet effective method now gaining traction in cath labs for improved hemostasis.✅ Full step-by-step guide✅ Practical tips from real-world cases✅ Why this matters for MCS management🎧 Want more insights like this? Join the conversation with leading interventionalists on MurmurMD.📲 Subscribe for more cath lab tips:YouTube: MurmurMD ChannelApp Store: Download the MurmurMD app#cardiology #Impella #Sideclose #cathlab #interventionalcardiology #MCS #hemostasis #TAVR #valve #surgery #Abiomed #cardiotips #medtech #shortsChapters:00:00 Intro and Managing Oozing02:00 The Side Closure Technique04:00 Managing Impella-related bleeding05:45 Managing Impella CP Bleeding08:00 Impella Removal and Hemostasis Technique10:25 Impella Repositioning and Potential Complications 12:35 Expanding Sideclose use and addressing potential complications

  42. 5

    Don't wait for cancer or a career ending injury- what you need to know!

    The Silent Epidemic in the Cath Lab: A Cardiologist’s Wake-Up Call What happens when saving lives starts to cost your own?Dr. Bob Foster, interventional cardiologist and co-founder of Rampart IC, opens up about the diagnosis that changed everything. What follows is a powerful and unfiltered conversation about radiation exposure, the outdated protection still used in cath labs, and the personal and professional toll it takes on frontline medical heroes.From ruptured discs to radiation-induced DNA damage, this episode dives deep into:The truth about radiation risk and cancer in healthcareWhy current lead aprons just aren’t enoughThe story behind Rampart: a breakthrough in radiation protectionThe future of safety in cardiology, EP, GI, and moreWhat it really takes to build a medtech startup from traumaWhether you're in medicine, innovation, or leadership—this episode is a wake-up call you can't ignore.Chapters: 00:00:00 Intro, Prostate cancer, and genetic expression00:03:30 Injuries and inadequate radiation protection in the cath lab00:05:45 Lack of formal radiation safety training and consequenses00:09:05 Overcoming challenges and expanding opportunities00:15:10 Risks and challenges in the cath lab00:21:15 Physician well-being and retention00:26:45 Addressing occupational hazards and radiation protection00:33:15 Abdominal shielding and radiation reduction techniques00:39:30 Radiation exposure and cancer prevention00:43:00 Intro to Rampart data and device considerations00:52:10 Radiation safety and protective measures01:04:30 Mitigating risks and impacts

  43. 4

    The Murmur Pod Featuring Dr. Tom Waggoner #1 WACTHMAN Implanter

    The #1 Watchman implanter in the world Tom Waggoner gives an overview of his experience with WATCHMAN FLX PRO as well as tips and tricks for growing your watchman program. Highlights: * Hemocoat technology designed to reduce DRT (70% reduction in thombus at 14 days, 50% increased endothelial coverage at 45 days) * Trial ongoing to investigate potential single anti-platelet therapy with new device *Reduce untreatable LAA's with 40 mm device (6% previously untreatable now treatable) * Fluoroscopic markers at shoulders to facilitate tug test and identify device position * Tom uses smaller TEE probe (57% smaller diameter) to do procedures with conscious sedation * Tom stops blood thinner at 90 days and images at 120 days to catch DRT (CHAMPION AF protocol) * Tom discusses his outreach strategy and how he uses patient-facing symposiums on the weekend to grow volume Like and subscribe to see more! Follow the MurmurMD Youtube for more tips: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA Download the MurmurMD app here: https://apps.apple.com/app/apple-store/id1586692687?pt=123231498&ct=curtis&mt=8 #cardiology #cardio #Surgery #cathlab #valve #TAVR #shorts #surgery #medical #medicalresearch #calcium #Boston #BostonScientific #Watchman #hearthealth #hearthealthawareness

  44. 3

    The Murmur Pod- Ep. 2 with Dr. David Daniels

    From discussing the adventures of innovating technology in the cardiology space, to breaking down why valve in valve is going to be an issue, this edition of The Murmur Podcast has it all! Special guest David Daniels, MD shares stories and insight from an extremely unique perspective in the interventional cardiology space! This is a must watch for learning about Solo Pace Inc, catching up on current innovations in cardiology, and discussing growth through mentorship. Like and subscribe to see more! Follow the MurmurMD Youtube for more tips: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA Download the MurmurMD app here: https://apps.apple.com/app/apple-store/id1586692687?pt=123231498&ct=curtis&mt=8 #cardiology #cardio #Surgery #cathlab #valve #TAVR #shorts #surgery #medical #medicalresearch #calcium #Edwards #EdwardsLifesciences #lifescience

  45. 2

    The Murmur Pod- Ep.1

    Dr. Aidan Raney and Dr. Joe Walsh introduce the MurmurMD podcast, talk updates about the app. They also recap TCT studies, talk about conferences, team morale, and discuss the case of the week! Intro and team morale- 0:35- 3:40 TCT Catchup- 3:40-6:45 Partner 3 vs. Evolut LR Apples to Apples- 6:45- 17:56 Case of the Week- 17:57- 34:54 Billing- 34:55- 37 Case recap- 37:01- 38:40 Murmur Updates- 38:41- end Like and subscribe to see more! Follow the MurmurMD Youtube for more tips: https://www.youtube.com/channel/UCfrLYhAhliQ2ZvXinkDCZvA Download the MurmurMD app here: https://apps.apple.com/app/apple-store/id1586692687?pt=123231498&ct=curtis&mt=8 #cardiology #cardio #Surgery #cathlab #valve #TAVR #shorts #surgery

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ABOUT THIS SHOW

The Murmur Pod is hosted by Dr. Aidan Raney III and Dr. Joe Walsh. Specializing in interventional cardiology, they explore happenings in the cardiology and medical communities, discuss interesting cases, review new technology, and more.This podcast is presented first in the MurmurMD App! Work in the cath lab? Reach out to join the private community there!

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