059 - Arthritis and Biosimilars

Arthritis: what it is; osteoarthritis vs. inflammatory arthritis; rheumatism; the risks and benefits of treatments // biosimilars, the “generic drugs” of biologics // Q&A: Chris’ qualms about omega-3 supplements for your heart // The Health Canada Ministry of Truth // Natural products claiming to cure cancer   * Jingle by Joseph Hackl * Additional original music by Seth Donnelly * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   Reference: 1) Cochrane review on exercise for arthritis: https://www.ncbi.nlm.nih.gov/pubmed/26405113   2) Aquatic exercise and arthritis: https://www.cochrane.org/CD005523/MUSKEL_aquatic-exercise-people-osteoarthritis-knee-or-hip   3) Weight loss and arthritis improvement: https://www.ncbi.nlm.nih.gov/pubmed/17204567   4) Tylenol meta-analyses: https://www.bmj.com/content/350/bmj.h1225 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31744-0/fulltext   5) Review on topical NSAIDs: https://www.cochrane.org/CD007402/SYMPT_topical-non-steroidal-anti-inflammatory-drugs-acute-musculoskeletal-pain-adults   6) Capsaicin as a treatment for chronic pain: https://www.cochrane.org/CD007393/SYMPT_capsaicin-applied-skin-chronic-neuropathic-pain-adults   7) Corticosteroids injections: https://www.ncbi.nlm.nih.gov/pubmed/26490760 https://www.ncbi.nlm.nih.gov/pubmed/28510679   8) Knee braces and orthotics: https://www.cochrane.org/CD004020/MUSKEL_braces-and-orthoses-for-osteoarthritis-of-the-knee   9) Duloxetien for knee pain: https://www.ncbi.nlm.nih.gov/pubmed/26176791   10) Glucosamine and chondroitin: https://www.nejm.org/doi/10.1056/NEJMoa052771?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dwww.ncbi.nlm.nih.gov   11) Trials fo knee surgery for arthritis: https://www.nejm.org/doi/full/10.1056/NEJMoa1505467   12) The omega-3 for cardiovascular disease meta-analysis: https://www.ncbi.nlm.nih.gov/pubmed/31567003?fbclid=IwAR31Z3qq07L9RULPuvFVyzTKavjgde3Mgl_A2LD7BTtw2u4ZZNvat8wAzEU   13) The CTV report on homeopathy: https://bit.ly/2IlNRSx   14) Bad Science Watch report on natural health products and cancer claims: https://badsciencewatch.ca/natural-health-product-retailers-sell-cancer-cures/     Music Credits:   Meanwhile in Bavaria by Kevin MacLeod Link: https://filmmusic.io/song/4028-meanwhile-in-bavaria License: http://creativecommons.org/licenses/by/4.0/   Countdown by Alexander Nakarada Link: https://filmmusic.io/song/4865-countdown License: http://creativecommons.org/licenses/by/4.0/   Imagefilm 036 by Sascha Ende Link: https://filmmusic.io/song/2941-imagefilm-036 License: http://creativecommons.org/licenses/by/4.0/