076 - Endometriosis / COVID Vaccine in Children / Aspirin a Day

What does the body of evidence have to say on the topic of endometriosis? Plus: Pfizer’s COVID-19 vaccine is authorized for children ages 5-11, and we go over why an aspirin a day is no longer suggested for many older adults.   Block 1: Endometriosis: what it is and what might be causing it (2:59)   Block 2: Endometriosis: risk factors, how common it is, diagnosis, treatments (8:37)   Block 3: FDA approves Pfizer’s COVID vaccine for children 5-11 years old (26:18)   Block 4: An aspirin a day to prevent cardiovascular disease? (40:19)     * Jingle by Joseph Hackl * Theme music: “Fall of the Ocean Queen“ by Joseph Hackl. * Assistant researcher: Nicholas Koziris   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   To make a one-time donation to our show, you can now use PayPal! https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Patrons get a bonus show on Patreon called “Digressions”! Check it out!     References:   1) Flow diagram of treatment of endometriosis from the Society of Obstetricians and Gynaecologists of Canada: https://sogc.org/common/Uploaded%20files/SOGC%20Endometriosis%20COVID19%20Update-%20Endo%20Group%20Edits%20April%2018%202020.pdf   2) Use of CA-125 to diagnosis endometriosis: https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1111/1471-0528.14055   3) Cochrane review of blood tests to diagnose endometriosis: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012281/full   4) Cochrane review of laparoscopic surgery to treat infertility associated with endometriosis: https://www.cochrane.org/CD011031/MENSTR_laparoscopic-surgery-pain-and-infertility-associated-endometriosis   5) Endometriosis time to diagnosis: https://academic.oup.com/humrep/article/18/4/756/596537 https://www.ajog.org/article/S0002-9378(19)30002-X/fulltext   6) FDA news release on authorization of Pfizer’s vaccine: https://www.fda.gov/news-events/press-announcements/fda-authorizes-pfizer-biontech-covid-19-vaccine-emergency-use-children-5-through-11-years-age   7) Pfizer’s press release on its trial of its COVID-19 vaccine in children: https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-announce-positive-topline-results   8) United States Preventive Services Task Force updated recommendation on aspirin for primary prevention: https://www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/aspirin-use-to-prevent-cardiovascular-disease-preventive-medication     Music Credits:   Dreams Of Success (loopable) by chilledmusic Link: https://filmmusic.io/song/8459-dreams-of-success-loopable- License: https://filmmusic.io/standard-license