103: Resistance Training Decelerates Brain Aging in Older Adults

This episode does a deep dive into an article from the journal GeroScience that details a randomized controlled trial investigating how resistance training impacts the biological aging of the brain in older adults. Researchers utilized resting-state fMRI and machine learning to develop brain clock models, which estimate an individual's "brain age" based on neural connectivity patterns. Gonzalez-Gomez R, Demnitz N, Coronel C, et al. Randomized controlled trial of resistance exercise and brain aging clocks. GeroScience. Published online February 10, 2026. doi:10.1007/s11357-026-02141-xFollow Dr. Anthony Novello, PT, DPT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@anthonynovello.dpt⁠⁠