12 9 2024

Hi, This Week in Medicine, we will be discussing

  New England Journal of Medicine

Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease

Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women

Xalnesiran with or without an Immunomodulator in Chronic Hepatitis B

Trastuzumab Deruxtecan after Endocrine Therapy in Metastatic Breast Cancer

Prenatal cfDNA Sequencing and Incidental Detection of Maternal Cancer

  Journal of  American Medical Association

HepB-CpG vs HepB-Alum Vaccine in People With HIV and Prior Vaccine NonresponseQuestion  Does vaccination with a hepatitis B vaccine with a cytosine phosphoguanine adjuvant (HepB-CpG vaccine) improve hepatitis B virus (HBV) seroprotection in people with HIV and nonresponse to prior hepatitis B vaccine?

Message Reminders to Improve Adherence to Chronic Cardiovascular Medications

 Annals of Internal Medicine

A Framework for Considering the Value of Race and Ethnicity in Estimating Disease Risk

  British Medical Journal

Chocolate intake and risk of type 2 diabetes: prospective cohort studies

 Lancet

Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial

 Journal of Clinical Oncology

Phase III KEYNOTE-789 Study of Pemetrexed and Platinum With or Without Pembrolizumab for Tyrosine Kinase Inhibitor‒Resistant, EGFR–Mutant, Metastatic Nonsquamous Non–Small Cell Lung Cancer

  journal of Hepatology

Differing genetic variants associated with liver fat and their contrasting relationships with cardiovascular diseases and cancer

  Gastroenterology

Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response

 Rheumatology 

 Axial Spondyloarthritis in Black Americans: An Observational Study From Five Centers in Shelby County, Tennessee

 Journal of Clinical Rheumatology 

Anticoagulant Treatment May Decrease the Relapse Rate of Pulmonary Arterial Involvement in Behçet’s Disease

  Circulation

 Restrictive Versus Liberal Transfusion in Patients With Type 1 or Type 2 Myocardial Infarction: A Prespecified Analysis of the MINT Trial

 Journals of the American College of Cardiology

Major Bleeding and Mortality After Revascularization of Left Main Disease

Diabetes care

Clinical Prediction Models Combining Routine Clinical Measures Have High Accuracy in Identifying Youth-Onset Type 2 Diabetes Defined by Maintained Endogenous Insulin Secretion: The SEARCH for Diabetes in Youth Study

 American Journal of Respiratory and Critical Care Medicine

Severity of Airflow Obstruction Based on FEV1/FVC Versus FEV1 Percent 

Kidney International reports

Prognosis for Type 1 Diabetes with Diabetic Nephropathy between 2000 and 2020 - Changes in Kidney Function Decline Over Time and Development of Cardiovascular Disease, Kidney Failure, and Mortality

Evaluation of Race-Neutral Glomerular Filtration Rate Estimating Equations in an Indian Population