#124 -GLP-1s and alcohol - the medical perspective with Professor Ahswin Dhanda, Prof. of Liver Medicine at the University of Plymouth

In this episode, Tabbin welcomes Professor Ashwin Danda, a leading expert in liver medicine, to discuss the intriguing potential of GLP-1 receptor agonists in addressing alcohol use disorder. Originally developed for diabetes management, these medications have garnered attention for their appetite-suppressing properties, which may offer new avenues for those struggling with alcohol dependency. Professor Danda explains the mechanisms by which GLP-1s operate, including their effects on insulin release and appetite regulation through interactions with the brain's reward systems. He highlights how these drugs could help mitigate cravings for alcohol, providing a critical window for individuals to engage in psychological therapies and make lasting lifestyle changes. Throughout the conversation, Tabbin and Professor Danda explore the implications of using GLP-1s in individuals with alcohol use disorder, particularly focusing on those with existing liver damage. They discuss the ongoing clinical trials aimed at assessing the safety and efficacy of these treatments in a population that urgently needs effective interventions. This episode sheds light on the promising intersection of pharmacology and psychology, emphasising the need for comprehensive support systems alongside any medical treatment. Join Tabbin and Professor Danda as they navigate this complex topic, offering hope for a healthier future for those affected by alcohol use disorder. Highlights:     (02:00) Introduction to GLP-1 receptor agonists and their original purpose     (10:15) Mechanisms of appetite suppression and potential effects on alcohol cravings     (18:30) Current clinical trials and their implications for alcohol use disorder     (25:00) The importance of psychosocial support in conjunction with medication     (32:45) Risks and considerations for using GLP-1s in individuals with alcohol use disorder     (40:00) Future directions and what the trials aim to uncover     (48:00) Reflections on the potential impact of GLP-1s on liver health and addiction recovery Connect with Tabbin: https://www.winetowatercoaching.com If you're interested in learning more about the intersection of pharmacology and alcohol recovery, consider reaching out for a free discovery call with Tabbin.