148 – Transcranial Magnetic Stimulation

The opening of a new private clinic spurs Chris and Sophie to ask whether Transcranial Magnetic Stimulation (TMS) is real medicine or pseudoscience. How does a magnetic field stimulate the brain and how is this different from electric convulsive therapy (ECT)? Also, a brief digression on One Flew Over the Cuckoo’s Nest and other classic movies Sophie has never seen.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at [email protected].   Editor:    Robyn Flynn Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris’ book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: 1) A study on the efficacy of ECT  by Slade et al. http://jamanetwork.com/article.aspx?doi=10.1001/jamapsychiatry.2017.1378 2) The accompany editorial on modern ECT use: Modern Electroconvulsive Therapy Vastly Improved yet Greatly Underused https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2633172 3) A study on the safety of ECT: Lancet Psychiatry study 2021 https://doi.org/10.1016/s2215-0366(21)00168-1 4) Consensus statement on the use of Transcranial Magnetic stimulation (TMS)  https://doi.org/10.4088/jcp.16cs10905 5) Network meta-analysis comparing different TMS modalities https://doi.org/10.1001/jamapsychiatry.2016.3644 6) The durability of response after TMS treatment: https://doi.org/10.1016/j.brs.2018.10.001 7) RCT comparing ECT and TMS and showing ECT is more effective:  https://pubmed.ncbi.nlm.nih.gov/17202547/ 8) The older cochrane review from 2002 suggesting little benefit: https://doi.org/10.1002/14651858.CD003493