#157 Adrian Ferrero: Reading the Microbes in Our Soil to Transform Global Agriculture episode artwork

EPISODE · Jul 10, 2026 · 48 MIN

#157 Adrian Ferrero: Reading the Microbes in Our Soil to Transform Global Agriculture

from PreVetted Podcast · host Federico Ramallo

Adrian Ferrero is the Co-Founder and CEO of Biome Makers, where for eleven years he has used DNA sequencing to read the communities of microbes living in soil and turn them into a functional picture of soil health. An economist by training who calls himself an innovator, Adrian sold an earlier DNA diagnostics company with his childhood friend Alberto Acedo, then reinvested everything to bring the personalized medicine concept into agriculture.In this episode, Adrian explains how Biome Makers profiles the bacteria and fungi in soil samples, why organic and conventional apples carry very different microbial loads, and how thinking about soil at a functional level rather than a taxonomic one let the company compare farms across 56 countries. He breaks down nutrient use efficiency, why nitrous oxide is hundreds of times more potent than carbon dioxide, and how better soil data helps farmers use less fertilizer while polluting less.The conversation also goes deep on the human side of building a company. Adrian shares why growing the team from two people to 55 was his hardest challenge, how he leads a remote and multicultural company across the US, Europe, Asia, and Latin America, and why he tries to keep business fun even in serious negotiations. He closes with a reminder not to underestimate our impact on the soil, and advice to build your own expectations and be brave enough to try.Chapters:00:00 Introduction to Biome Makers and Adrian Ferrero03:21 The Role of Microbes in Agriculture11:11 Understanding Soil Health and Nutrient Efficiency16:22 Clients and Services of Biome Makers21:05 Establishing Standards in Soil Health Technology25:29 Functional Diversity of Soil Microbes28:35 Understanding Soil Microbial Communities30:44 Challenges of Team Building in Startups35:47 Cultural Dynamics in Global Business46:10 The Importance of Soil and EntrepreneurshipLinkedIn · WebsiteEpisode 157 of the PreVetted Podcast.

Adrian Ferrero is the Co-Founder and CEO of Biome Makers, where for eleven years he has used DNA sequencing to read the communities of microbes living in soil and turn them into a functional picture of soil health. An economist by training who calls himself an innovator, Adrian sold an earlier DNA diagnostics company with his childhood friend Alberto Acedo, then reinvested everything to bring the personalized medicine concept into agriculture.In this episode, Adrian explains how Biome Makers profiles the bacteria and fungi in soil samples, why organic and conventional apples carry very different microbial loads, and how thinking about soil at a functional level rather than a taxonomic one let the company compare farms across 56 countries. He breaks down nutrient use efficiency, why nitrous oxide is hundreds of times more potent than carbon dioxide, and how better soil data helps farmers use less fertilizer while polluting less.The conversation also goes deep on the human side of building a company. Adrian shares why growing the team from two people to 55 was his hardest challenge, how he leads a remote and multicultural company across the US, Europe, Asia, and Latin America, and why he tries to keep business fun even in serious negotiations. He closes with a reminder not to underestimate our impact on the soil, and advice to build your own expectations and be brave enough to try.Chapters:00:00 Introduction to Biome Makers and Adrian Ferrero03:21 The Role of Microbes in Agriculture11:11 Understanding Soil Health and Nutrient Efficiency16:22 Clients and Services of Biome Makers21:05 Establishing Standards in Soil Health Technology25:29 Functional Diversity of Soil Microbes28:35 Understanding Soil Microbial Communities30:44 Challenges of Team Building in Startups35:47 Cultural Dynamics in Global Business46:10 The Importance of Soil and EntrepreneurshipLinkedIn · WebsiteEpisode 157 of the PreVetted Podcast.

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#157 Adrian Ferrero: Reading the Microbes in Our Soil to Transform Global Agriculture

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Adrian Ferrero is the Co-Founder and CEO of Biome Makers, where for eleven years he has used DNA sequencing to read the communities of microbes living in soil and turn them into a functional picture of soil health. An economist by training who calls...

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