169: Deep mutational scanning of the insulin receptor guides precision therapy for insulin resistance

Aslanzadeh V et al., Nature Communications - Deep mutational scanning of the insulin receptor guides precision therapy for insulin resistance Music:Enjoy the music based on this article at the end of the episode. Article title:Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance First author:Aslanzadeh V Journal:Nature Communications DOI:10.1038/s41467-025-64178-4 Reference:Aslanzadeh V., Brierley G.V., Kumar R., Çubuk H., Vigouroux C., Matreyek K.A., et al.. Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance. Nature Communications, 16. (2025). https://doi.org/10.1038/s41467-025-64178-4 Support:Base by Base – Stripe donations: https://donate.stripe.com/7sY4gz71B2sN3RWac5gEg00 Official website https://basebybase.com On PaperCast Base by Base you'll discover the latest in genomics, functional genomics, structural genomics, and proteomics. Episode link: https://basebybase.com/episodes/deep-mutational-scanning-of-the-insulin-receptor-guides-precision-therapy-for-insulin-resistance