170: Maternal Age, Meiotic Recombination Failure, and Triploidy in Humans

Picchetta L et al., The American Journal of Human Genetics - Maternal Age, Meiotic Recombination Failure, and Triploidy in Humans Music:Enjoy the music based on this article at the end of the episode. Article title:Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans First author:Picchetta L Journal:The American Journal of Human Genetics DOI:10.1016/j.ajhg.2025.09.014 Reference:Picchetta L., Ottolini C.S., Tao X., Zhan Y., Jobanputra V., Vallejo C.M., et al.. Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans. The American Journal of Human Genetics, 112, 2665-2678. (2025). https://doi.org/10.1016/j.ajhg.2025.09.014 Support:Base by Base – Stripe donations: https://donate.stripe.com/7sY4gz71B2sN3RWac5gEg00 Official website https://basebybase.com On PaperCast Base by Base you'll discover the latest in genomics, functional genomics, structural genomics, and proteomics. Episode link: https://basebybase.com/episodes/maternal-age-meiotic-recombination-failure-and-triploidy-in-humans