3 3 2025

Hi, This Week in Medicine, we will be discussing

 New England Journal of Medicine

Highly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans

Embolization of the Middle Meningeal Artery for Chronic Subdural Hematoma

Oral Infigratinib Therapy in Children with Achondroplasia

 Journal of  American Medical Association

First-Line Sugemalimab Plus Chemotherapy for Advanced Gastric Cancer: The GEMSTONE-303 Randomized Clinical Trial

Medicaid Spending and Health-Related Social Needs in the North Carolina Healthy Opportunities Pilots Program

 Annals of Internal Medicine

Glucagon-Like Peptide-1 Receptor Agonists and Risk for Depression in Older Adults With Type 2 Diabetes: A Target Trial Emulation Study

  British Medical Journal

Glucagon-like peptide-1 receptor agonists and risk of suicidality among patients with type 2 diabetes: active comparator, new user cohort study

  Lancet

Endoscopic, ultrasound-guided, radiofrequency ablation of aldosterone-producing adenomas (FABULAS): a UK, multicentre, prospective, proof-of-concept trial

  Journal of Clinical Oncology

Nodal Burden and Oncologic Outcomes in Patients With Residual Isolated Tumor Cells After Neoadjuvant Chemotherapy

 journal of Hepatology

Variation in intention-to-treat survival by MELD subtypes: All models created for end-stage liver disease are not equal

 Clinical Gastroenterology

Meta-Analysis of Endoscopic Full-Thickness Resection Versus Endoscopic Submucosal Dissection for Complex Colorectal Lesions

  Rheumatology 

A Randomized Controlled Trial of Efficacy and Safety of Fecal Microbiota Transplant for Preventing Recurrent Clostridioides difficileInfection

 Journal of Clinical Rheumatology 

Circulation

Arterial-Lymphatic-Like Endothelial Cells Appear in Hereditary Hemorrhagic Telangiectasia 2 and Contribute to Vascular Leakage and Arteriovenous Malformations

 Journals of the American College of Cardiology

Intensive Lifestyle Intervention, Cardiac Biomarkers, and Cardiovascular Outcomes in Diabetes: Look AHEAD Cardiac Biomarker Ancillary Study

  JAMA Cardiology

Interpreting Population Mean Treatment Effects in the Kansas City Cardiomyopathy QuestionnaireA Patient-Level Meta-Analysis

  Journal of Clinical Endocrinology & Metabolism

Clinical and Biochemical Data for the Diagnosis of Endogenous Hypercortisolism: The “Cushingomic” Approach

 Neurology

Utility of Progression Independent of Relapse Activity as a Trial Outcome in Relapsing-Remitting Multiple Sclerosis

  Chest

The Responsiveness of Exercise Tests in COPD

A Randomized Controlled Trial

 The American Journal of Respiratory and Critical Care Medicine

Humidified Noninvasive Ventilation versus High-Flow Therapy to Prevent Reintubation in Patients with Obesity: A Randomized Clinical Trial

 Clinical Journal of American Society of Nephrology

Efficacy and Safety of Admilparant, an LPA1 Antagonist, in Pulmonary Fibrosis: A Phase 2 Randomized Clinical Trial

  Kidney International reports

Impact of Different CKD Definitions on Long-Term Renal Function and Mortality in a Population-Based Cohort Study