EPISODE · Apr 28, 2026 · 43 MIN
#42 The Hormonal Orchestra: Why Willpower Isn't Enough to Manage Hunger
from Prevention is Cure · host PREKURE - Prof Grant Schofield
Prof. Grant Schofield and Kayla dive into the science and break down the five key hormones controlling appetite, insulin, leptin, ghrelin, the incretins (GIP & GLP-1), and cortisol and explain why willpower alone can never beat a dysregulated hormonal system. They explore metabolic flexibility, why cycling in and out of ketosis is normal human physiology (not a fad), and how exercise context should drive your fuelling strategy.
What this episode covers
Prof. Grant Schofield and Kayla dive into the science and break down the five key hormones controlling appetite, insulin, leptin, ghrelin, the incretins (GIP & GLP-1), and cortisol and explain why willpower alone can never beat a dysregulated hormonal system. They explore metabolic flexibility, why cycling in and out of ketosis is normal human physiology (not a fad), and how exercise context should drive your fuelling strategy.
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#42 The Hormonal Orchestra: Why Willpower Isn't Enough to Manage Hunger
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