45. Case Study: SIBO, Histamine Intolerance & Hormonal Imbalance episode artwork

EPISODE · Apr 27, 2026 · 16 MIN

45. Case Study: SIBO, Histamine Intolerance & Hormonal Imbalance

from Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health · host Joanne Kennedy

In this episode of The Histamine Well, Joanne shares a powerful clinical case study exploring the connection between SIBO (Small Intestinal Bacterial Overgrowth), histamine intolerance, hormonal imbalance, estrogen dominance, gut health, bloating, acne, fatigue, and PMS symptoms.This episode follows the journey of a 37-year-old woman who experienced rapid body changes over two years — including unexplained weight gain, chronic bloating, severe PMS, hormonal acne, headaches, fluid retention, breast tenderness, digestive discomfort, and low energy. Through functional testing and a naturopathic treatment approach, Joanne uncovers how gut dysfunction, histamine overload, and hormone imbalance can work together to drive chronic symptoms.You’ll discover how SIBO contributes to nutrient malabsorption, inflammation, estrogen dominance, histamine intolerance, and digestive dysfunction, along with why symptoms such as bloating, fatigue, skin issues, and menstrual changes are often connected.In this episode, Joanne discusses:The link between SIBO, histamine intolerance, and hormonal imbalanceWhy bloating, PMS, headaches, and acne may stem from gut dysfunctionThe difference between hydrogen and methane SIBOHow nutrient deficiencies affect hormones, mood, and energyWhy is bowel motility essential for successful SIBO treatmentThe role of biofilms in persistent gut symptomsFunctional medicine strategies for improving gut and hormone healthWhether you are a practitioner, student, or someone navigating digestive and hormone-related symptoms, this episode offers practical insight into the deep connection between gut health, histamine, hormones, and systemic inflammation.✨ Want more? Follow on Instagram, Facebook, and YouTube for updates and tips.📘 New to this journey? Buy The Ultimate Bundle for Managing Histamine Intolerance—your step-by-step guide to manage your histamine intolerance effectively. 🧪 Curious about your methylation status? Try our at-home Methylation Test! In just 15 minutes, discover if you're over-methylating or under-methylating and receive targeted supplement recommendations to help rebalance. Use code HISTAMINEWELL10 for 10% off.🎓 Practitioner or student? Join the waitlist for the Histamine & Methylation Online Group Coaching Course starting early 2026!📆 Work with us 1:1! Book a consultation and take your first step to real healing.🎤 Have a topic suggestion? Submit it here!

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45. Case Study: SIBO, Histamine Intolerance & Hormonal Imbalance

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Frequently Asked Questions

How long is this episode of Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health?

This episode is 16 minutes long.

When was this Histamine Well Podcast: Exploring Histamine, Methylation & Holistic Health episode published?

This episode was published on April 27, 2026.

What is this episode about?

In this episode of The Histamine Well, Joanne shares a powerful clinical case study exploring the connection between SIBO (Small Intestinal Bacterial Overgrowth), histamine intolerance, hormonal imbalance, estrogen dominance, gut health, bloating,...

Is there a transcript available for this episode?

Yes, a full transcript is available for this episode. You can read the complete transcript on the episode page.

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